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The map label for this gene is yxnA [H]

Identifier: 78046762

GI number: 78046762

Start: 1351222

End: 1352202

Strand: Reverse

Name: yxnA [H]

Synonym: XCV1206

Alternate gene names: 78046762

Gene position: 1352202-1351222 (Counterclockwise)

Preceding gene: 78046766

Following gene: 78046761

Centisome position: 26.11

GC content: 65.44

Gene sequence:

>981_bases
ATGCATCGCACCCCTCCTGCCCACGTGGTGATTTCCGGCGCGTCCAGCGGCATCGGCCAAGCCACTGCAGAAGCATTCGC
CGAACAAGGCGCGCGCCTGGTGCTGGCTGCACGCGGCGAAGAAGCCCTCAATGCGGTTGCCGAACGCTGCCGTGCGCGCG
GTGCCGAAGTCTTGGTGGCGCCCACCGACGTCAAACAGGCCGAACAGGTCAAGGCACTGGCCACCAGCGCGCAGAGTTTT
CTGGGCCGCATCGACCTGTGGTTCGGCAATGTCGGGGTGGGCACGGTCGGCAAATTCCACGAGGTACCGATGGAAGCAAG
CGCGGCCGTCATCCACGCCAATCTGCTCGGTCGCATGCACGACGCCCATGCCGCCATCCCCATCTTCGTCGAACAAGGCC
ACGGCATCTTCGTCAACATGATCTCTTCGGGCGGCTTTGCATCCACGCCGTTTGCAGCGGCGTACGGCGCCAGCAAATTC
GGCCAGCGCGGCTTTTCCGAAGCGTTACGCGCCGAGCTGAGCGACTACCCGCATATCCACGTGTGCGATGTGTACCCGTA
CTTCGTCGACACGCCAGGCCTGACCCATGGCGCCAATTACGTGGGCCGCCGCATCAGCGGGCCGCCGTTGATGCTGGACA
CCCGCACCGTCGCGGCAGCTGTCGTGCGCCTGCTGGACCGGCCACGCAACACGGTAGTGTTGGGCACCGCTGTCCATGCG
ATGCGCCTGGGTCATGCGCTGGCACCGCAGACCCTGGCGCGCGCCATGTACCGTATCTTCAAGCAGTATCTTGCGCAGGC
ACCACAGGTGGCGCGATCCAGCGGCAATGTGTTCGCAGCGCCCGGCATTGCCGGCGGCATCGACGGTGGCTACCGGCGGC
GCCCCGCGTTGCGGGCACGCTCTGCGCACGACAAGATGTTGATCGGTGCGGCCGCTGCAGCAGTAACGGGTTTGGCAGTG
CTGGCTTTACGACGCAAGTGA

Upstream 100 bases:

>100_bases
CAGCCCGACAAGTTCAGCTTCACGCTACGGTACGCAAAGCGCCGCACCGTGTTCACGCACGACGATCAAGCATGCCTGCT
CGTTTTCGTGGAGACATCGC

Downstream 100 bases:

>100_bases
GTCGCTGAAGTCTGCAGTGCCGTGCCGACAGTTGCGCGTTTGCCAGCGATTTCCAAACGCTGCGGCAACGCGGGAAAGTA
GACCAGCCTCAATGCGACAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MHRTPPAHVVISGASSGIGQATAEAFAEQGARLVLAARGEEALNAVAERCRARGAEVLVAPTDVKQAEQVKALATSAQSF
LGRIDLWFGNVGVGTVGKFHEVPMEASAAVIHANLLGRMHDAHAAIPIFVEQGHGIFVNMISSGGFASTPFAAAYGASKF
GQRGFSEALRAELSDYPHIHVCDVYPYFVDTPGLTHGANYVGRRISGPPLMLDTRTVAAAVVRLLDRPRNTVVLGTAVHA
MRLGHALAPQTLARAMYRIFKQYLAQAPQVARSSGNVFAAPGIAGGIDGGYRRRPALRARSAHDKMLIGAAAAAVTGLAV
LALRRK

Sequences:

>Translated_326_residues
MHRTPPAHVVISGASSGIGQATAEAFAEQGARLVLAARGEEALNAVAERCRARGAEVLVAPTDVKQAEQVKALATSAQSF
LGRIDLWFGNVGVGTVGKFHEVPMEASAAVIHANLLGRMHDAHAAIPIFVEQGHGIFVNMISSGGFASTPFAAAYGASKF
GQRGFSEALRAELSDYPHIHVCDVYPYFVDTPGLTHGANYVGRRISGPPLMLDTRTVAAAVVRLLDRPRNTVVLGTAVHA
MRLGHALAPQTLARAMYRIFKQYLAQAPQVARSSGNVFAAPGIAGGIDGGYRRRPALRARSAHDKMLIGAAAAAVTGLAV
LALRRK
>Mature_326_residues
MHRTPPAHVVISGASSGIGQATAEAFAEQGARLVLAARGEEALNAVAERCRARGAEVLVAPTDVKQAEQVKALATSAQSF
LGRIDLWFGNVGVGTVGKFHEVPMEASAAVIHANLLGRMHDAHAAIPIFVEQGHGIFVNMISSGGFASTPFAAAYGASKF
GQRGFSEALRAELSDYPHIHVCDVYPYFVDTPGLTHGANYVGRRISGPPLMLDTRTVAAAVVRLLDRPRNTVVLGTAVHA
MRLGHALAPQTLARAMYRIFKQYLAQAPQVARSSGNVFAAPGIAGGIDGGYRRRPALRARSAHDKMLIGAAAAAVTGLAV
LALRRK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=182, Percent_Identity=32.4175824175824, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI4503817, Length=195, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI142976729, Length=185, Percent_Identity=28.6486486486486, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=29.3193717277487, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40254992, Length=222, Percent_Identity=32.4324324324324, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI40807363, Length=221, Percent_Identity=28.9592760180996, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI157739938, Length=190, Percent_Identity=30, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI22507405, Length=182, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI31543615, Length=231, Percent_Identity=27.7056277056277, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI210032110, Length=185, Percent_Identity=26.4864864864865, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI32455239, Length=171, Percent_Identity=32.7485380116959, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI5031765, Length=171, Percent_Identity=32.7485380116959, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI25282469, Length=307, Percent_Identity=26.7100977198697, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787820, Length=202, Percent_Identity=27.2277227722772, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87082100, Length=184, Percent_Identity=29.8913043478261, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787335, Length=183, Percent_Identity=27.3224043715847, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=235, Percent_Identity=24.2553191489362, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=181, Percent_Identity=27.6243093922652, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=181, Percent_Identity=27.6243093922652, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71997402, Length=187, Percent_Identity=26.7379679144385, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=25.6544502617801, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=171, Percent_Identity=29.2397660818713, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=251, Percent_Identity=30.6772908366534, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=27.8350515463918, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24580925, Length=173, Percent_Identity=31.7919075144509, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24644339, Length=168, Percent_Identity=33.9285714285714, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281364892, Length=221, Percent_Identity=28.0542986425339, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI23397609, Length=186, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357041, Length=167, Percent_Identity=28.7425149700599, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737361, Length=197, Percent_Identity=29.4416243654822, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007236, Length=239, Percent_Identity=25.1046025104602, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34325; Mature: 34325

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRTPPAHVVISGASSGIGQATAEAFAEQGARLVLAARGEEALNAVAERCRARGAEVLVA
CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEE
PTDVKQAEQVKALATSAQSFLGRIDLWFGNVGVGTVGKFHEVPMEASAAVIHANLLGRMH
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
DAHAAIPIFVEQGHGIFVNMISSGGFASTPFAAAYGASKFGQRGFSEALRAELSDYPHIH
HCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCEE
VCDVYPYFVDTPGLTHGANYVGRRISGPPLMLDTRTVAAAVVRLLDRPRNTVVLGTAVHA
EEECCCEEECCCCCCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEHHHHHH
MRLGHALAPQTLARAMYRIFKQYLAQAPQVARSSGNVFAAPGIAGGIDGGYRRRPALRAR
HHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHH
SAHDKMLIGAAAAAVTGLAVLALRRK
CCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHRTPPAHVVISGASSGIGQATAEAFAEQGARLVLAARGEEALNAVAERCRARGAEVLVA
CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEE
PTDVKQAEQVKALATSAQSFLGRIDLWFGNVGVGTVGKFHEVPMEASAAVIHANLLGRMH
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
DAHAAIPIFVEQGHGIFVNMISSGGFASTPFAAAYGASKFGQRGFSEALRAELSDYPHIH
HCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCEE
VCDVYPYFVDTPGLTHGANYVGRRISGPPLMLDTRTVAAAVVRLLDRPRNTVVLGTAVHA
EEECCCEEECCCCCCCCHHHHCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEHHHHHH
MRLGHALAPQTLARAMYRIFKQYLAQAPQVARSSGNVFAAPGIAGGIDGGYRRRPALRAR
HHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHH
SAHDKMLIGAAAAAVTGLAVLALRRK
CCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]