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The map label for this gene is prpR [H]

Identifier: 78046711

GI number: 78046711

Start: 1282984

End: 1284633

Strand: Reverse

Name: prpR [H]

Synonym: XCV1155

Alternate gene names: 78046711

Gene position: 1284633-1282984 (Counterclockwise)

Preceding gene: 78046725

Following gene: 78046696

Centisome position: 24.81

GC content: 66.42

Gene sequence:

>1650_bases
ATGCAACGGCTGATCCACTATGAAACATCATTGAAACGCGACACCGTCATGCGCCCCCCTGCCCCTCCGGAAACCGCAGA
CGCCTCCTTGCCCATCATCTGGACCGTCAGCGTCTCGCGCCTGACCGGCCTGCTGGCCGATGTCATCCCCGAGTTCGACC
AGCGCGCGCGCATCGAGCAGATCAACCTCGGCTTTGCCGAAGCGGTCGAGGTCATCGGCCAGCGCCTGCGCCGCGAGCGC
TGCGACGCGCTGGTGGCCGGCGGATCCAATGCGGCGTACCTGCGCAGCCGGCTCGCGCTGCCCTTGGCGCCCATCCAGGC
CACCGGGTTCGATCTGATGGAAGCGCTGGCGCGTGCGCGCCGCATTGCGCCACGCATCGGCGTGGTCACCCACGCCACCG
ATGTGCCGTCGTTCCGCGCGTTTCAGCACAGCTTCGATCTGGAGATCGAACACCGCCGTTTCGTCACCGCCGAAGACGCA
CGCGACTGCATTGCCGATCTGCGCGCCAGCGGCATCCAGGTCATTGTCGGCACCGGCATGGCGATCGATTTCGCCGAGCA
GGCCGGGCTGCCTGGCGTGCTGCTGTATTCGGCCGATTCGGTGCGTCATGCGCTGGAACAGGCCATCACGCTGGGCACCG
CTCCAAGCATCGATCGCGTCGCCGGCCGTGCCGCCCCGCGCCGCGCACGACGCGCCGACGCCCTGCTGGGCGAAGACGGC
GCAATGCGGCGCGTGCGCGAGCTGGTGCAGCTCTACGCACCGCATACCGGCACCGTGTTGATCAGCGGCGACACCGGCAC
CGGCAAGGAACTGGTCGCACGACAACTGCATGCCGGCAGTCGTCGCCGCGGCCGTTTCGTGGCGATCAACTGTGGCGCCA
TCAGCGAATCGTTGCTGGAGGCGGAACTGTTCGGCTACAGCGACGGCGCCTTCACCGGTGCACGTCGCGGCGGCCACACC
GGCCTGATCGAAGCCGCGCAGGACGGCACGCTGTTCCTCGACGAAATCGGCGAATTGCCCGTGCCGTTGCAGACTCGGCT
ACTGCGCGTCCTGGAAGAACGTGAAGTAGTGCGTGTCGGCGCAACGGTGCCCGTTGCGATCGACGTGCGCGTGGTCGCCG
CCAGCCTGCTGGACCTGCAGCAGTTGGTCGAACAAGGCCGCTTCCGCCGCGACCTGTTCTATCGCCTTGCCGCGCTGCGC
ATCGCACTGCCTCCGTTGCGCAATCGCCGCAACGACATTGCGTTGTTGCTTGCGCATTATTTCCAGCAACTCGGCAGCAT
CGCATCGCCGTTATCGCCAGCGGCATTGCAACGCCTGCAACAGCACACCTGGCCCGGCAACGTACGCGAACTGCGCAACC
TGGTCGAACGCCTGTGCATTCACTGGAAATCCCAACCGCACGACAGCCTCAGCCTAGAACAACTCGAACGCTGGGCGCCG
GAATTATTCGATACGCATTTCGGCAACCACGAAGCACCGCGTGAGCTTGCCGATTTGGCAACCTCTCGCCTGCAGCTCAC
TGCCACCGCAGTCCGCGCAGCGCTCGACCGCGCCAACGGCAACCGCGCCCTTGCCGCGCAAGCGCTCGGCGTCTCGCGCA
CCACGCTGTGGCGCTGGATGCAGGCGCAGGCGGTGGCATCGCGTGCATAA

Upstream 100 bases:

>100_bases
ATGGCGGTTCCTTGGATGGGATCCACCGTACAGGCGCAAGCACCATGCCAAGTACAAGTCGTTGATTTGATGACAATCCC
ACACGCCAATTGTTGCAAAA

Downstream 100 bases:

>100_bases
GGCAAGCGCGAACTCGCGCGGCTGACCAGGCCACACATAGAGGCGCGGCCTTCCACACTCAGGCGACAATGAATGGCATG
CACGCTCGGCGCATGAATGC

Product: propionate catabolism regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MQRLIHYETSLKRDTVMRPPAPPETADASLPIIWTVSVSRLTGLLADVIPEFDQRARIEQINLGFAEAVEVIGQRLRRER
CDALVAGGSNAAYLRSRLALPLAPIQATGFDLMEALARARRIAPRIGVVTHATDVPSFRAFQHSFDLEIEHRRFVTAEDA
RDCIADLRASGIQVIVGTGMAIDFAEQAGLPGVLLYSADSVRHALEQAITLGTAPSIDRVAGRAAPRRARRADALLGEDG
AMRRVRELVQLYAPHTGTVLISGDTGTGKELVARQLHAGSRRRGRFVAINCGAISESLLEAELFGYSDGAFTGARRGGHT
GLIEAAQDGTLFLDEIGELPVPLQTRLLRVLEEREVVRVGATVPVAIDVRVVAASLLDLQQLVEQGRFRRDLFYRLAALR
IALPPLRNRRNDIALLLAHYFQQLGSIASPLSPAALQRLQQHTWPGNVRELRNLVERLCIHWKSQPHDSLSLEQLERWAP
ELFDTHFGNHEAPRELADLATSRLQLTATAVRAALDRANGNRALAAQALGVSRTTLWRWMQAQAVASRA

Sequences:

>Translated_549_residues
MQRLIHYETSLKRDTVMRPPAPPETADASLPIIWTVSVSRLTGLLADVIPEFDQRARIEQINLGFAEAVEVIGQRLRRER
CDALVAGGSNAAYLRSRLALPLAPIQATGFDLMEALARARRIAPRIGVVTHATDVPSFRAFQHSFDLEIEHRRFVTAEDA
RDCIADLRASGIQVIVGTGMAIDFAEQAGLPGVLLYSADSVRHALEQAITLGTAPSIDRVAGRAAPRRARRADALLGEDG
AMRRVRELVQLYAPHTGTVLISGDTGTGKELVARQLHAGSRRRGRFVAINCGAISESLLEAELFGYSDGAFTGARRGGHT
GLIEAAQDGTLFLDEIGELPVPLQTRLLRVLEEREVVRVGATVPVAIDVRVVAASLLDLQQLVEQGRFRRDLFYRLAALR
IALPPLRNRRNDIALLLAHYFQQLGSIASPLSPAALQRLQQHTWPGNVRELRNLVERLCIHWKSQPHDSLSLEQLERWAP
ELFDTHFGNHEAPRELADLATSRLQLTATAVRAALDRANGNRALAAQALGVSRTTLWRWMQAQAVASRA
>Mature_549_residues
MQRLIHYETSLKRDTVMRPPAPPETADASLPIIWTVSVSRLTGLLADVIPEFDQRARIEQINLGFAEAVEVIGQRLRRER
CDALVAGGSNAAYLRSRLALPLAPIQATGFDLMEALARARRIAPRIGVVTHATDVPSFRAFQHSFDLEIEHRRFVTAEDA
RDCIADLRASGIQVIVGTGMAIDFAEQAGLPGVLLYSADSVRHALEQAITLGTAPSIDRVAGRAAPRRARRADALLGEDG
AMRRVRELVQLYAPHTGTVLISGDTGTGKELVARQLHAGSRRRGRFVAINCGAISESLLEAELFGYSDGAFTGARRGGHT
GLIEAAQDGTLFLDEIGELPVPLQTRLLRVLEEREVVRVGATVPVAIDVRVVAASLLDLQQLVEQGRFRRDLFYRLAALR
IALPPLRNRRNDIALLLAHYFQQLGSIASPLSPAALQRLQQHTWPGNVRELRNLVERLCIHWKSQPHDSLSLEQLERWAP
ELFDTHFGNHEAPRELADLATSRLQLTATAVRAALDRANGNRALAAQALGVSRTTLWRWMQAQAVASRA

Specific function: Involved in the transcriptional regulation of the propionate catabolism operon [H]

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1786524, Length=541, Percent_Identity=46.5804066543438, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=43.5736677115987, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1788550, Length=297, Percent_Identity=41.7508417508418, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1790437, Length=316, Percent_Identity=40.1898734177215, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1788905, Length=415, Percent_Identity=35.9036144578313, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI87082117, Length=228, Percent_Identity=49.1228070175439, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI87081872, Length=313, Percent_Identity=41.2140575079872, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=39.7590361445783, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI87082152, Length=273, Percent_Identity=41.025641025641, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1789087, Length=228, Percent_Identity=44.7368421052632, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1787583, Length=237, Percent_Identity=38.3966244725738, Blast_Score=152, Evalue=7e-38,
Organism=Escherichia coli, GI87081858, Length=312, Percent_Identity=32.0512820512821, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789828, Length=229, Percent_Identity=34.061135371179, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR012704
- InterPro:   IPR010524 [H]

Pfam domain/function: PF02954 HTH_8; PF06506 PrpR_N; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 60373; Mature: 60373

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLIHYETSLKRDTVMRPPAPPETADASLPIIWTVSVSRLTGLLADVIPEFDQRARIEQ
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
INLGFAEAVEVIGQRLRRERCDALVAGGSNAAYLRSRLALPLAPIQATGFDLMEALARAR
HCCCHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RIAPRIGVVTHATDVPSFRAFQHSFDLEIEHRRFVTAEDARDCIADLRASGIQVIVGTGM
HHCCCCCEEEECCCCCCHHHHHHCCCCEECCCEEECHHHHHHHHHHHHHCCEEEEEECCC
AIDFAEQAGLPGVLLYSADSVRHALEQAITLGTAPSIDRVAGRAAPRRARRADALLGEDG
EEEHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHCCCH
AMRRVRELVQLYAPHTGTVLISGDTGTGKELVARQLHAGSRRRGRFVAINCGAISESLLE
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHH
AELFGYSDGAFTGARRGGHTGLIEAAQDGTLFLDEIGELPVPLQTRLLRVLEEREVVRVG
HHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHEEEC
ATVPVAIDVRVVAASLLDLQQLVEQGRFRRDLFYRLAALRIALPPLRNRRNDIALLLAHY
CCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FQQLGSIASPLSPAALQRLQQHTWPGNVRELRNLVERLCIHWKSQPHDSLSLEQLERWAP
HHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ELFDTHFGNHEAPRELADLATSRLQLTATAVRAALDRANGNRALAAQALGVSRTTLWRWM
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHH
QAQAVASRA
HHHHHHHCC
>Mature Secondary Structure
MQRLIHYETSLKRDTVMRPPAPPETADASLPIIWTVSVSRLTGLLADVIPEFDQRARIEQ
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
INLGFAEAVEVIGQRLRRERCDALVAGGSNAAYLRSRLALPLAPIQATGFDLMEALARAR
HCCCHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RIAPRIGVVTHATDVPSFRAFQHSFDLEIEHRRFVTAEDARDCIADLRASGIQVIVGTGM
HHCCCCCEEEECCCCCCHHHHHHCCCCEECCCEEECHHHHHHHHHHHHHCCEEEEEECCC
AIDFAEQAGLPGVLLYSADSVRHALEQAITLGTAPSIDRVAGRAAPRRARRADALLGEDG
EEEHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHCCCH
AMRRVRELVQLYAPHTGTVLISGDTGTGKELVARQLHAGSRRRGRFVAINCGAISESLLE
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHH
AELFGYSDGAFTGARRGGHTGLIEAAQDGTLFLDEIGELPVPLQTRLLRVLEEREVVRVG
HHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHEEEC
ATVPVAIDVRVVAASLLDLQQLVEQGRFRRDLFYRLAALRIALPPLRNRRNDIALLLAHY
CCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
FQQLGSIASPLSPAALQRLQQHTWPGNVRELRNLVERLCIHWKSQPHDSLSLEQLERWAP
HHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ELFDTHFGNHEAPRELADLATSRLQLTATAVRAALDRANGNRALAAQALGVSRTTLWRWM
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHH
QAQAVASRA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]