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The map label for this gene is gst2 [H]

Identifier: 78046591

GI number: 78046591

Start: 1162356

End: 1162970

Strand: Reverse

Name: gst2 [H]

Synonym: XCV1035

Alternate gene names: 78046591

Gene position: 1162970-1162356 (Counterclockwise)

Preceding gene: 78046592

Following gene: 78046588

Centisome position: 22.46

GC content: 60.98

Gene sequence:

>615_bases
ATGAAGCTGTATACCAAGCCCGGCGCTTGTTCGCTGGCAGATCACATCGTGTTGCGTTGGTCGGGGCTGCCGTTCGACCT
GAGTGTGGTCGATGCGGCAACGATGAAATCTCCCGAGTATCTGCGTCTGAATCCAGCAGGCTCGGTGCCATTGCTGATGG
TCGACGATTGGGCACTGACCCAGAATGCAGCCATTCTCAATTACATCGCCGACATCGCACCACTCACCGGCCTATCCGGC
GATGGCACCGCGCGCAGCCGTGCCGAGATCAATCGGTGGATCGCCTTCGTCAATGCCGACGTGCACCCCACCTTCAAGCC
GATCTTCGGCAGCACCGCGTATCTGCAGGACCCGGCGCTGATTGCGCGCAGCCAGGACGATGCGCGCAGCAAATTGCGCA
CGCTGTACGAGCGCGTCGATGCGCATCTGCAAGGTCGCACCTGGCTCGCCAGCGACAGCCACACCGGTGCCGATGCGTAT
TTGTTCGTCACCTTGCTGTGGGCGCAGAAAGTTGCGGTGAATCTGGATGGATTGAATGCGCTGCAGGCGTTCGTGCAACG
CATGCTGGCCGATGCCGATGTGCAGGCTGCACTCAAGGCCGAAGGCCTGGCCTGA

Upstream 100 bases:

>100_bases
CCAATGAGCGGCGCCCTGCTGAAGCCCAATTCCCGCTGCGCGCTTCACACGGCATCGTCTGCCCGCTAAGCTTGGGTCTT
CATTCCCGCGTAGATCGTCC

Downstream 100 bases:

>100_bases
CCGCGCAGTCTCTGCCACGCGAGGCGCAATAAAAAAAACGCCGGGCAATGCCCGGCGTTTTCATAACAGCAGTGACCGAA
TAACTCAGCCCAGCAGATGC

Product: glutathione transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKLYTKPGACSLADHIVLRWSGLPFDLSVVDAATMKSPEYLRLNPAGSVPLLMVDDWALTQNAAILNYIADIAPLTGLSG
DGTARSRAEINRWIAFVNADVHPTFKPIFGSTAYLQDPALIARSQDDARSKLRTLYERVDAHLQGRTWLASDSHTGADAY
LFVTLLWAQKVAVNLDGLNALQAFVQRMLADADVQAALKAEGLA

Sequences:

>Translated_204_residues
MKLYTKPGACSLADHIVLRWSGLPFDLSVVDAATMKSPEYLRLNPAGSVPLLMVDDWALTQNAAILNYIADIAPLTGLSG
DGTARSRAEINRWIAFVNADVHPTFKPIFGSTAYLQDPALIARSQDDARSKLRTLYERVDAHLQGRTWLASDSHTGADAY
LFVTLLWAQKVAVNLDGLNALQAFVQRMLADADVQAALKAEGLA
>Mature_204_residues
MKLYTKPGACSLADHIVLRWSGLPFDLSVVDAATMKSPEYLRLNPAGSVPLLMVDDWALTQNAAILNYIADIAPLTGLSG
DGTARSRAEINRWIAFVNADVHPTFKPIFGSTAYLQDPALIARSQDDARSKLRTLYERVDAHLQGRTWLASDSHTGADAY
LFVTLLWAQKVAVNLDGLNALQAFVQRMLADADVQAALKAEGLA

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=207, Percent_Identity=38.6473429951691, Blast_Score=124, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 22196; Mature: 22196

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYTKPGACSLADHIVLRWSGLPFDLSVVDAATMKSPEYLRLNPAGSVPLLMVDDWALT
CCCCCCCCCCCHHHEEEEEECCCCEEHHHHHHHHCCCCCEEEECCCCCCCEEEECCCHHC
QNAAILNYIADIAPLTGLSGDGTARSRAEINRWIAFVNADVHPTFKPIFGSTAYLQDPAL
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEEEECCCCCCCHHHCCCCCEECCCHH
IARSQDDARSKLRTLYERVDAHLQGRTWLASDSHTGADAYLFVTLLWAQKVAVNLDGLNA
EECCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHEEECCCHHH
LQAFVQRMLADADVQAALKAEGLA
HHHHHHHHHHCCHHHHHHHCCCCC
>Mature Secondary Structure
MKLYTKPGACSLADHIVLRWSGLPFDLSVVDAATMKSPEYLRLNPAGSVPLLMVDDWALT
CCCCCCCCCCCHHHEEEEEECCCCEEHHHHHHHHCCCCCEEEECCCCCCCEEEECCCHHC
QNAAILNYIADIAPLTGLSGDGTARSRAEINRWIAFVNADVHPTFKPIFGSTAYLQDPAL
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEEEECCCCCCCHHHCCCCCEECCCHH
IARSQDDARSKLRTLYERVDAHLQGRTWLASDSHTGADAYLFVTLLWAQKVAVNLDGLNA
EECCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHEEECCCHHH
LQAFVQRMLADADVQAALKAEGLA
HHHHHHHHHHCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217; 8342943 [H]