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The map label for this gene is rlmM [H]

Identifier: 78046480

GI number: 78046480

Start: 1053868

End: 1054911

Strand: Reverse

Name: rlmM [H]

Synonym: XCV0924

Alternate gene names: 78046480

Gene position: 1054911-1053868 (Counterclockwise)

Preceding gene: 78046481

Following gene: 78046478

Centisome position: 20.37

GC content: 66.0

Gene sequence:

>1044_bases
ATGAGCGGCCTGGTGTGTTATTGCCGGCAGGGTTTCGAACCTGAGCTGGCCGCAGAACTGAGCGCGCGCGCTGCATTCGT
CGGTATCGCCGGGTATGCGCGCACCCAACGCAACGACGGCTATGTGCTGTTCGTCTGCGACGAGGCTGCGCAACTTGCAG
CAAAACTGCAGTGGCGCGAGTTGATCTTCGCCCGGCAAAAGCTGGTGGTGATTGCCGAGCTGAAAGGTATCGATCCCAAG
GACCGCATCACGCCGATCCTGGCCGCGTTGGACGGGCACCAGCGGTTTGGCGATCTGTGGGTGGAACACCCGGATTCGGA
CGCCGGCAAGCCGCTTGCAGGCCTGGCGCGCAGCTTCGGCAATGCACTGCGACCGGCCCTGCGTAAGGCCGGCCTGCTCA
CCGACAAGCCGCAGCTGCGCCAACCGCGGTTGCACGTCTGTTTTCTCGACGGCGACCACGCCGTGCTGGCGGTGGCCGAC
AACGCCGACAGCGCGCCGTGGCCGCTGGGCATTCCACGCCTGAAATTGCTGCCGGAAGCGCCTTCGCGCTCTGCCCTCAA
GCTCGACGAGGCCCTGCTGACGCTGCTCACGCCCGAAGAACGCGACGCACTGGTCAAGCCGGGCATGCGCGCGGCCGATC
TGGGCGCTGCGCCCGGCGGCTGGACCTGGGTACTGACGCGGCAGCACGTGCACGTCACCAGCGTGGACAACGGCCCGCTG
CGCGAGCATGTGCTGGAGACCGGGCTGGTGGAGCACCTGCGCGCCGACGGCTTCCACTGGAAGCCCGCGCAGCCGCTGGA
CTGGATGGTCTGCGACATGGTCGAGCAACCGCGCCGCGTGGCCGAACGCATGGCCACCTGGGTGCGCGAAGGCTGGTGCC
GCAACACCATCTTCAACCTCAAGCTGCCGATGAAAAAGCGCTGGGACGAGACCCGCCTGTGCCTGGACCTGTTCGAGCAA
CAGGCAGAAAAATCATTGATCGTGCGCGCCAAGCAGCTGTATCACGATCGCGAGGAGATCACGGTACTGGCGATGCGGGA
GTGA

Upstream 100 bases:

>100_bases
GCGCGACCAGGCGTGTGCAGTGCTGCGCAACTATGGCGAGGGCGGCGGTGACCATTACTGATGTCGCCGGCGCAGCGGGC
GCCCTCCTGCAGGTGCAGCG

Downstream 100 bases:

>100_bases
GGCTGGGATTCGGGATTTGGGATTCGGGAATCGGGAATCGGGAATCGTAAAAGCGGTTGGCCGGTTCGGCTGTATATGCT
GTCGTCGATTCCTTCGACCA

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSGLVCYCRQGFEPELAAELSARAAFVGIAGYARTQRNDGYVLFVCDEAAQLAAKLQWRELIFARQKLVVIAELKGIDPK
DRITPILAALDGHQRFGDLWVEHPDSDAGKPLAGLARSFGNALRPALRKAGLLTDKPQLRQPRLHVCFLDGDHAVLAVAD
NADSAPWPLGIPRLKLLPEAPSRSALKLDEALLTLLTPEERDALVKPGMRAADLGAAPGGWTWVLTRQHVHVTSVDNGPL
REHVLETGLVEHLRADGFHWKPAQPLDWMVCDMVEQPRRVAERMATWVREGWCRNTIFNLKLPMKKRWDETRLCLDLFEQ
QAEKSLIVRAKQLYHDREEITVLAMRE

Sequences:

>Translated_347_residues
MSGLVCYCRQGFEPELAAELSARAAFVGIAGYARTQRNDGYVLFVCDEAAQLAAKLQWRELIFARQKLVVIAELKGIDPK
DRITPILAALDGHQRFGDLWVEHPDSDAGKPLAGLARSFGNALRPALRKAGLLTDKPQLRQPRLHVCFLDGDHAVLAVAD
NADSAPWPLGIPRLKLLPEAPSRSALKLDEALLTLLTPEERDALVKPGMRAADLGAAPGGWTWVLTRQHVHVTSVDNGPL
REHVLETGLVEHLRADGFHWKPAQPLDWMVCDMVEQPRRVAERMATWVREGWCRNTIFNLKLPMKKRWDETRLCLDLFEQ
QAEKSLIVRAKQLYHDREEITVLAMRE
>Mature_346_residues
SGLVCYCRQGFEPELAAELSARAAFVGIAGYARTQRNDGYVLFVCDEAAQLAAKLQWRELIFARQKLVVIAELKGIDPKD
RITPILAALDGHQRFGDLWVEHPDSDAGKPLAGLARSFGNALRPALRKAGLLTDKPQLRQPRLHVCFLDGDHAVLAVADN
ADSAPWPLGIPRLKLLPEAPSRSALKLDEALLTLLTPEERDALVKPGMRAADLGAAPGGWTWVLTRQHVHVTSVDNGPLR
EHVLETGLVEHLRADGFHWKPAQPLDWMVCDMVEQPRRVAERMATWVREGWCRNTIFNLKLPMKKRWDETRLCLDLFEQQ
AEKSLIVRAKQLYHDREEITVLAMRE

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=354, Percent_Identity=44.3502824858757, Blast_Score=288, Evalue=4e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 38999; Mature: 38867

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLVCYCRQGFEPELAAELSARAAFVGIAGYARTQRNDGYVLFVCDEAAQLAAKLQWRE
CCCEEEEECCCCCHHHHHHHHHHHHEEEEHHHHCCCCCCCEEEEEECCHHHHHHHHHHHH
LIFARQKLVVIAELKGIDPKDRITPILAALDGHQRFGDLWVEHPDSDAGKPLAGLARSFG
HHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCHHHCCCEEECCCCCCCCCHHHHHHHHH
NALRPALRKAGLLTDKPQLRQPRLHVCFLDGDHAVLAVADNADSAPWPLGIPRLKLLPEA
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCEEECCCC
PSRSALKLDEALLTLLTPEERDALVKPGMRAADLGAAPGGWTWVLTRQHVHVTSVDNGPL
CCCCHHHHHHHHHHHCCCCCCCHHHCCCCCHHHCCCCCCCEEEEEEECEEEEEECCCCHH
REHVLETGLVEHLRADGFHWKPAQPLDWMVCDMVEQPRRVAERMATWVREGWCRNTIFNL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCEEEE
KLPMKKRWDETRLCLDLFEQQAEKSLIVRAKQLYHDREEITVLAMRE
ECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure 
SGLVCYCRQGFEPELAAELSARAAFVGIAGYARTQRNDGYVLFVCDEAAQLAAKLQWRE
CCEEEEECCCCCHHHHHHHHHHHHEEEEHHHHCCCCCCCEEEEEECCHHHHHHHHHHHH
LIFARQKLVVIAELKGIDPKDRITPILAALDGHQRFGDLWVEHPDSDAGKPLAGLARSFG
HHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCHHHCCCEEECCCCCCCCCHHHHHHHHH
NALRPALRKAGLLTDKPQLRQPRLHVCFLDGDHAVLAVADNADSAPWPLGIPRLKLLPEA
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCEEECCCC
PSRSALKLDEALLTLLTPEERDALVKPGMRAADLGAAPGGWTWVLTRQHVHVTSVDNGPL
CCCCHHHHHHHHHHHCCCCCCCHHHCCCCCHHHCCCCCCCEEEEEEECEEEEEECCCCHH
REHVLETGLVEHLRADGFHWKPAQPLDWMVCDMVEQPRRVAERMATWVREGWCRNTIFNL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCEEEE
KLPMKKRWDETRLCLDLFEQQAEKSLIVRAKQLYHDREEITVLAMRE
ECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]