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The map label for this gene is csiR [H]

Identifier: 78046468

GI number: 78046468

Start: 1041679

End: 1042353

Strand: Reverse

Name: csiR [H]

Synonym: XCV0912

Alternate gene names: 78046468

Gene position: 1042353-1041679 (Counterclockwise)

Preceding gene: 78046472

Following gene: 78046462

Centisome position: 20.13

GC content: 66.37

Gene sequence:

>675_bases
ATGGAGCCAATGGCGAACAACCACCGATTGCAAGCGATCCAGCAGCTACGCGAATTGATCCTGTGCGGCACCTTCGCGCC
GGGCGAGCGCCTCACCGAGGCGGCACTGGCCGAGCGCCTGGCGCTTTCGCGCACGCCGATCCGCCAGGCCCTGCCGGCGT
TGTGCCAGGAAGGCCTGCTGGTGCAGGCAGGCAACCGTGGTTACGCCGTGCGGCGCTTCAGCCAGCAGGAAAGCCTGGAT
GCACTAGCGGTGCGCGCAGTGATGGAAGGCATGGCCGCGCGCACCGTCGCCGAACGGGGCGCCCCCGCCGAGTTGCTCGC
CACCTTGTACGCCTGCCTGGGCGAAGGCGACCGCATCCTGGCCAGCCGCAATCTCCGTGCCGACGACGAGCAGGCATATG
GCGCAATGAATGCCCGTTTCCATCGCGCCATCGTGGAGGCGGCCAACAAGCCGATCCTGACCGAAACGGTGGAGCGCTGC
ACCTTGGTGCCGTTCGTCAGCCCGGTCAACGTCGTGTTCGGCCAACGCACTGCCGCGCTTGCCTACGACGATCTGTTTTA
CGGACACAGGCAACACGGCGCGATCGTCTCGGCCATCGAGCAACGCGATGGCGCACGCGCGGAATTGCTGTTCCGCGAAC
ACGCCAACACGCAACGGCACAGCATGGGACTGTGA

Upstream 100 bases:

>100_bases
TCCAAATTGCCATCAAGCGATCTCATCCGCAAGGTTTTTATACACGTAAGTGCGAGTTTTCCCTGTCGAAGGAACGTGCG
CTGCGGTATGGCGCGAGAGA

Downstream 100 bases:

>100_bases
GACGAGCGCTTTGCTCGTCGATACCCCTGCGCGCCAAGCACCCGGCTTGAGCGATGAGGCCGGACCTCCCGCGCAAGCAG
GTTCGCGTGACGGATCGCAT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: Carbon starvation induced regulator [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MEPMANNHRLQAIQQLRELILCGTFAPGERLTEAALAERLALSRTPIRQALPALCQEGLLVQAGNRGYAVRRFSQQESLD
ALAVRAVMEGMAARTVAERGAPAELLATLYACLGEGDRILASRNLRADDEQAYGAMNARFHRAIVEAANKPILTETVERC
TLVPFVSPVNVVFGQRTAALAYDDLFYGHRQHGAIVSAIEQRDGARAELLFREHANTQRHSMGL

Sequences:

>Translated_224_residues
MEPMANNHRLQAIQQLRELILCGTFAPGERLTEAALAERLALSRTPIRQALPALCQEGLLVQAGNRGYAVRRFSQQESLD
ALAVRAVMEGMAARTVAERGAPAELLATLYACLGEGDRILASRNLRADDEQAYGAMNARFHRAIVEAANKPILTETVERC
TLVPFVSPVNVVFGQRTAALAYDDLFYGHRQHGAIVSAIEQRDGARAELLFREHANTQRHSMGL
>Mature_224_residues
MEPMANNHRLQAIQQLRELILCGTFAPGERLTEAALAERLALSRTPIRQALPALCQEGLLVQAGNRGYAVRRFSQQESLD
ALAVRAVMEGMAARTVAERGAPAELLATLYACLGEGDRILASRNLRADDEQAYGAMNARFHRAIVEAANKPILTETVERC
TLVPFVSPVNVVFGQRTAALAYDDLFYGHRQHGAIVSAIEQRDGARAELLFREHANTQRHSMGL

Specific function: Modulates expression of csiD and lhgO in a temporal manner during entry into stationary phase or during the first few hours of carbon starvation [H]

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082149, Length=217, Percent_Identity=33.1797235023041, Blast_Score=84, Evalue=8e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 24604; Mature: 24604

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPMANNHRLQAIQQLRELILCGTFAPGERLTEAALAERLALSRTPIRQALPALCQEGLL
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEE
VQAGNRGYAVRRFSQQESLDALAVRAVMEGMAARTVAERGAPAELLATLYACLGEGDRIL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEE
ASRNLRADDEQAYGAMNARFHRAIVEAANKPILTETVERCTLVPFVSPVNVVFGQRTAAL
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHH
AYDDLFYGHRQHGAIVSAIEQRDGARAELLFREHANTQRHSMGL
HHHHHHHCCHHCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure
MEPMANNHRLQAIQQLRELILCGTFAPGERLTEAALAERLALSRTPIRQALPALCQEGLL
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEE
VQAGNRGYAVRRFSQQESLDALAVRAVMEGMAARTVAERGAPAELLATLYACLGEGDRIL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEE
ASRNLRADDEQAYGAMNARFHRAIVEAANKPILTETVERCTLVPFVSPVNVVFGQRTAAL
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHH
AYDDLFYGHRQHGAIVSAIEQRDGARAELLFREHANTQRHSMGL
HHHHHHHCCHHCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8297211; 7984428 [H]