Click here to switch to the map view.

The map label for this gene is 78046460

Identifier: 78046460

GI number: 78046460

Start: 1034133

End: 1035041

Strand: Reverse

Name: 78046460

Synonym: XCV0904

Alternate gene names: NA

Gene position: 1035041-1034133 (Counterclockwise)

Preceding gene: 78046461

Following gene: 78046459

Centisome position: 19.99

GC content: 68.54

Gene sequence:

>909_bases
ATGTTGGTCTTTACCCATCCCGCCTGCCTCGGTCACGACGCCGGCCCTGAGCACCCGGAGAGCCCCGCCCGCCTGGAAGC
GGTCGTCCAGGCCCTGCGCGGCGCATTCCCAGATCTGGACTGGCGCGAAGCGCCGTTGGCCAAGCTGGGCGACCTGTGCC
GCGTGCACGAGCGCGAGCAGGTGGATGCGGTGCTGGAAACCGCCTTCGACGGCTATCGTCAGCTGGACGTGGATACACGC
ATGGTGCCGGCCTCGCGCGCGGCCGCCTTGCGCGCCGCAGGCGCCGGCATCGCCGCGGTCGATGCGGTGATGCAGGACCA
GGCCCGCACCGCCTTCTGCGCCGTGCGTCCGCCCGGTCACCACGCCACCGCACAGGTGTCGATGGGATTTTGCCTGTTCA
ACAACATCGCCGTGGCCGCCGCCCACGCCCGCGACCGGCATGGGCTGGAACGCATCACCATCGTGGATTTCGACGTCCAT
CACGGTAACGGCACCCAGGCGATCTTCGAACGCGACCCCACCGTGCAGTACCTGAGCACCCACCAGTCCGGGCTGTATCC
GCATTCGGGCAGCGTGTACGAGCGCGGCGTCGGCAATATCCACAACCTGCTGCTGCCACCGGGCAGCGACGGGCTGCGCT
TCCGTAATGTCTGGGAAGACGAGATGCTGCCGCTCGTCGATGCCTTCCGCCCGCAATTGATCCTGATCTCCGCCGGCTTC
GATGCGCATCTGCGCGACCCACTGGCCGACCTGATGCTGGACGACGACGATTTCGCCTGGCTCACCGGCGCGCTGCGCAC
ACTCGCCGACCGCCATGCACGCGGCCGCGTGGTCTCGATGCTGGAAGGCGGCTACGACCTGCAGGCGCTGCGCGAAAGCA
GCGTGGCGCACGTGGCAGCGCTGCGCTGA

Upstream 100 bases:

>100_bases
TGCTGGCGCGTGCCGATGGTCGGCAGGAAGTCCTGTGGCGGCACGACCGCCGACGCGGTTGAGCATGTGCCCGGGTCGGC
ACAGAGGCTAGAGTTGCCCC

Downstream 100 bases:

>100_bases
ACCCCGGCCAGGGCGCCGGTCGCGTCACCGAGTGCGATGAACCTCGCCCTCCCGGCGCCGGCGCTCTTCATTGCCCCTAT
GCGGGGTATGCGGCAAGCTA

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MLVFTHPACLGHDAGPEHPESPARLEAVVQALRGAFPDLDWREAPLAKLGDLCRVHEREQVDAVLETAFDGYRQLDVDTR
MVPASRAAALRAAGAGIAAVDAVMQDQARTAFCAVRPPGHHATAQVSMGFCLFNNIAVAAAHARDRHGLERITIVDFDVH
HGNGTQAIFERDPTVQYLSTHQSGLYPHSGSVYERGVGNIHNLLLPPGSDGLRFRNVWEDEMLPLVDAFRPQLILISAGF
DAHLRDPLADLMLDDDDFAWLTGALRTLADRHARGRVVSMLEGGYDLQALRESSVAHVAALR

Sequences:

>Translated_302_residues
MLVFTHPACLGHDAGPEHPESPARLEAVVQALRGAFPDLDWREAPLAKLGDLCRVHEREQVDAVLETAFDGYRQLDVDTR
MVPASRAAALRAAGAGIAAVDAVMQDQARTAFCAVRPPGHHATAQVSMGFCLFNNIAVAAAHARDRHGLERITIVDFDVH
HGNGTQAIFERDPTVQYLSTHQSGLYPHSGSVYERGVGNIHNLLLPPGSDGLRFRNVWEDEMLPLVDAFRPQLILISAGF
DAHLRDPLADLMLDDDDFAWLTGALRTLADRHARGRVVSMLEGGYDLQALRESSVAHVAALR
>Mature_302_residues
MLVFTHPACLGHDAGPEHPESPARLEAVVQALRGAFPDLDWREAPLAKLGDLCRVHEREQVDAVLETAFDGYRQLDVDTR
MVPASRAAALRAAGAGIAAVDAVMQDQARTAFCAVRPPGHHATAQVSMGFCLFNNIAVAAAHARDRHGLERITIVDFDVH
HGNGTQAIFERDPTVQYLSTHQSGLYPHSGSVYERGVGNIHNLLLPPGSDGLRFRNVWEDEMLPLVDAFRPQLILISAGF
DAHLRDPLADLMLDDDDFAWLTGALRTLADRHARGRVVSMLEGGYDLQALRESSVAHVAALR

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=306, Percent_Identity=38.2352941176471, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI13128864, Length=311, Percent_Identity=35.3697749196142, Blast_Score=161, Evalue=5e-40,
Organism=Homo sapiens, GI17158039, Length=231, Percent_Identity=39.8268398268398, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI30795204, Length=231, Percent_Identity=39.8268398268398, Blast_Score=144, Evalue=8e-35,
Organism=Homo sapiens, GI30795202, Length=231, Percent_Identity=39.8268398268398, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI153085395, Length=232, Percent_Identity=39.6551724137931, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI148539870, Length=231, Percent_Identity=38.5281385281385, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI169234807, Length=231, Percent_Identity=38.5281385281385, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI226529806, Length=299, Percent_Identity=36.4548494983278, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI62750349, Length=243, Percent_Identity=36.2139917695473, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI62750347, Length=243, Percent_Identity=36.2139917695473, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI13128862, Length=259, Percent_Identity=25.8687258687259, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI8923769, Length=175, Percent_Identity=27.4285714285714, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=307, Percent_Identity=34.2019543973941, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI193206283, Length=301, Percent_Identity=34.5514950166113, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17540332, Length=301, Percent_Identity=34.5514950166113, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193209491, Length=330, Percent_Identity=33.9393939393939, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25154020, Length=224, Percent_Identity=32.1428571428571, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI25154022, Length=224, Percent_Identity=31.6964285714286, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17537347, Length=294, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17534739, Length=170, Percent_Identity=27.6470588235294, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324307, Length=318, Percent_Identity=30.8176100628931, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6325141, Length=322, Percent_Identity=26.0869565217391, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325325, Length=170, Percent_Identity=28.2352941176471, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323999, Length=270, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24642146, Length=300, Percent_Identity=34.6666666666667, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24642142, Length=300, Percent_Identity=34.6666666666667, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24642144, Length=300, Percent_Identity=34.6666666666667, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI281360899, Length=300, Percent_Identity=34.6666666666667, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24641720, Length=337, Percent_Identity=34.1246290801187, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI281360801, Length=337, Percent_Identity=34.1246290801187, Blast_Score=137, Evalue=8e-33,
Organism=Drosophila melanogaster, GI281360799, Length=337, Percent_Identity=34.1246290801187, Blast_Score=137, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 32979; Mature: 32979

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVFTHPACLGHDAGPEHPESPARLEAVVQALRGAFPDLDWREAPLAKLGDLCRVHEREQ
CEEEECCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VDAVLETAFDGYRQLDVDTRMVPASRAAALRAAGAGIAAVDAVMQDQARTAFCAVRPPGH
HHHHHHHHHCCCEEECCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCC
HATAQVSMGFCLFNNIAVAAAHARDRHGLERITIVDFDVHHGNGTQAIFERDPTVQYLST
CCEEEEEECHHHHHCHHHEEHHHHHCCCCCEEEEEEEEEECCCCCCEEEECCCCHHHHHH
HQSGLYPHSGSVYERGVGNIHNLLLPPGSDGLRFRNVWEDEMLPLVDAFRPQLILISAGF
CCCCCCCCCCCHHHHCCCCHHHEECCCCCCCCEECCCCHHHHHHHHHHCCCEEEEEECCC
DAHLRDPLADLMLDDDDFAWLTGALRTLADRHARGRVVSMLEGGYDLQALRESSVAHVAA
CCHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHH
LR
CC
>Mature Secondary Structure
MLVFTHPACLGHDAGPEHPESPARLEAVVQALRGAFPDLDWREAPLAKLGDLCRVHEREQ
CEEEECCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VDAVLETAFDGYRQLDVDTRMVPASRAAALRAAGAGIAAVDAVMQDQARTAFCAVRPPGH
HHHHHHHHHCCCEEECCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCC
HATAQVSMGFCLFNNIAVAAAHARDRHGLERITIVDFDVHHGNGTQAIFERDPTVQYLST
CCEEEEEECHHHHHCHHHEEHHHHHCCCCCEEEEEEEEEECCCCCCEEEECCCCHHHHHH
HQSGLYPHSGSVYERGVGNIHNLLLPPGSDGLRFRNVWEDEMLPLVDAFRPQLILISAGF
CCCCCCCCCCCHHHHCCCCHHHEECCCCCCCCEECCCCHHHHHHHHHHCCCEEEEEECCC
DAHLRDPLADLMLDDDDFAWLTGALRTLADRHARGRVVSMLEGGYDLQALRESSVAHVAA
CCHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHH
LR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]