Click here to switch to the map view.

The map label for this gene is betT [H]

Identifier: 78046332

GI number: 78046332

Start: 887752

End: 889731

Strand: Reverse

Name: betT [H]

Synonym: XCV0776

Alternate gene names: 78046332

Gene position: 889731-887752 (Counterclockwise)

Preceding gene: 78046333

Following gene: 78046331

Centisome position: 17.18

GC content: 63.64

Gene sequence:

>1980_bases
ATGAGTGCGACAGCGCCGCACACCTTGCCGGTACGCACCCTGCGCCCGGTGTTCGTGCTGGCTGCCACGGTCGTGTGCAC
GTTTGCCTTGCTGGTGTCGTTGTTTCCGCTGGAATCGGGGCGTGTGCTGCTGGATGCGCAGACCTGGGCGTCGCGCAATG
TCGGCTGGTATTACCTGCTGGCGATGACGCTGTATCTGGTGTTCGTGCTGGCCACGGCCCTGTCCAGCTACGGCAACATC
AAGCTCGGCGCCGATCACGACGAGCCGGAATTCAGTTATCTCTCCTGGGCCGGCATGCTGTTCGCCGCCGGCATCAGCAT
CACGCTGTTCTTCTTCTGCGTCTCCGAGCCGCTCACGCATTATCTGCAACCGCCCCAGGGCGGTACCGGCAGTGGCGAGG
CGTCCGCGAGACAGGCGATGCAGGTGCTGTTCCTGCATTGGGGCCTGCATGGATGGGGAGTGTTCGCACTGGCCGCCATG
GCGCTGGCGTATTTCGCCTTCCGCCATAACCTGCCGCTGGCGTTACGCTCGGCGTTGTACCCGCTGATCGGCAAACGCAT
CAACGGGCCGATCGGCTATACCGTGGATGCGTTGGGCATCGTGGCCACCGTGTTCGGCCTGGGCGCGGACATGGGCTTTG
GCGTGCTGCATCTCAACGCCGGCCTGAGTACCTTGATGGACGTGCCGCATACGCACTGGGTGCAGGTGGCGCTGATCGTG
GCGATGATGGGCGCGGCCATCGTGGTGGCGGTGTCCGGCGTCGAAAAAGGCGTGCGCTGGATGTCGGACATCAACATGCT
GCTGGCCATTGCGCTGCTGTTGTTCATGCTGTTCGCCGGCCCGACGCAGTACCTGCTCAATGCGCTGATGCAAAACCTGG
GCGACTACCTGGGCAGCGTGGTCAACAAGAGTTTCGACGTGTATGCCTACGGTGGCCGCGCCGATTGGCTGGGCAACTGG
ACGGTGTTTTATTGGGCCTGGTGGATCGGCTGGGCGCCGTTCGTCGGGCTGTTCATCGCGCGCATCTCGCGCGGCCGCAC
CATTCGCGAATTCGTGTTGGGGGTATTGCTGATCCCGCTCGGGTTTACCCTGGCGTGGCTGTCGATCTTCGGCAACAGCG
CGCTGGATCAGCTGCTGCATCACGGCCAGGCAGCATGGGCGCAGCAGGCCATCGATGCACCGCAGACGGTGTTGTATTCC
CTGCTGCAGAGTTACCCCTGGAGCCGCACGGTGATCACGGTCACGGTGGCGATCAGTTTCGTGTTCTTCGTGACCTCCGC
CGATTCCGGCACGGTGGTGTTGTCCACGCTCTCCTCCCACGGCGGCGAACCGCACGACGATGGCCCGCGCTGGCTGCGCG
TGTTCTGGGGCGTGCTCACTGCCGTGGTCACGGCAGGCTTGTTGCTGGCCGGCAGCATGGAAGCCCTGAAATCGGCGGTG
GTGCTGGCGTCGCTGCCATTCTCTGCAGTGCTGCTGCTGATGGCCTGGGGCCTGTCACGCGCCCTCAGCGAAGAATCGCA
GCGCAAACGCGCGCAGCTTTACAGCCCCAGCCCGTTGATCGGGCAATCGCGTCATCACGGCGGCTGGCGCCAGCGGTTGG
GCCAGGCGATGCACTTCCCGGCGCGCGATGAGGTGTATCGCTTCATGCACGACCAGGTGCGCCCGGCCATCGAAGCGGTC
ACCGCACAGCTGCAGGAGGAAGGCTGGAAGGTCAGCAGCCGCATCGACGACGGCGACATGGAAATCAGCGTCGATCATGG
CGAACAGCAGGGTTTCCGCTATCAAATCGTGATGCGCGGCTATCTGACCCCGTCGTTTGCCGCGCAGCGCTTCCGCAACC
AGCGCTACTACCGCGCCGAGGTCTACCTGTACGAAGGCAGCCAGGACTACGACCTGGTGGGCTACAGCCGCGAACAGATC
ATCAACGACATCATCGATCAATACGAACGTCACCTGCAGTTTCTGCACCTCACCCGCTGA

Upstream 100 bases:

>100_bases
ACTCGACCGCTGACACCCCCTCGACACCGCCTGTGCGATAACGCAGGCGGTTTTTCGTTGGGAGCACAACACGTGATACG
CAGCGTATGAGTGCGTTGCC

Downstream 100 bases:

>100_bases
AGGTGCGTCGCTGCGGCGACCGTCCCACAGGAGGTTTGTCATGCCACGTTTTTCCGACCAGTTGCTGTATATCGGCGGCC
GTTATGTTCCCGCTCGCGGC

Product: BCCT family protein

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MSATAPHTLPVRTLRPVFVLAATVVCTFALLVSLFPLESGRVLLDAQTWASRNVGWYYLLAMTLYLVFVLATALSSYGNI
KLGADHDEPEFSYLSWAGMLFAAGISITLFFFCVSEPLTHYLQPPQGGTGSGEASARQAMQVLFLHWGLHGWGVFALAAM
ALAYFAFRHNLPLALRSALYPLIGKRINGPIGYTVDALGIVATVFGLGADMGFGVLHLNAGLSTLMDVPHTHWVQVALIV
AMMGAAIVVAVSGVEKGVRWMSDINMLLAIALLLFMLFAGPTQYLLNALMQNLGDYLGSVVNKSFDVYAYGGRADWLGNW
TVFYWAWWIGWAPFVGLFIARISRGRTIREFVLGVLLIPLGFTLAWLSIFGNSALDQLLHHGQAAWAQQAIDAPQTVLYS
LLQSYPWSRTVITVTVAISFVFFVTSADSGTVVLSTLSSHGGEPHDDGPRWLRVFWGVLTAVVTAGLLLAGSMEALKSAV
VLASLPFSAVLLLMAWGLSRALSEESQRKRAQLYSPSPLIGQSRHHGGWRQRLGQAMHFPARDEVYRFMHDQVRPAIEAV
TAQLQEEGWKVSSRIDDGDMEISVDHGEQQGFRYQIVMRGYLTPSFAAQRFRNQRYYRAEVYLYEGSQDYDLVGYSREQI
INDIIDQYERHLQFLHLTR

Sequences:

>Translated_659_residues
MSATAPHTLPVRTLRPVFVLAATVVCTFALLVSLFPLESGRVLLDAQTWASRNVGWYYLLAMTLYLVFVLATALSSYGNI
KLGADHDEPEFSYLSWAGMLFAAGISITLFFFCVSEPLTHYLQPPQGGTGSGEASARQAMQVLFLHWGLHGWGVFALAAM
ALAYFAFRHNLPLALRSALYPLIGKRINGPIGYTVDALGIVATVFGLGADMGFGVLHLNAGLSTLMDVPHTHWVQVALIV
AMMGAAIVVAVSGVEKGVRWMSDINMLLAIALLLFMLFAGPTQYLLNALMQNLGDYLGSVVNKSFDVYAYGGRADWLGNW
TVFYWAWWIGWAPFVGLFIARISRGRTIREFVLGVLLIPLGFTLAWLSIFGNSALDQLLHHGQAAWAQQAIDAPQTVLYS
LLQSYPWSRTVITVTVAISFVFFVTSADSGTVVLSTLSSHGGEPHDDGPRWLRVFWGVLTAVVTAGLLLAGSMEALKSAV
VLASLPFSAVLLLMAWGLSRALSEESQRKRAQLYSPSPLIGQSRHHGGWRQRLGQAMHFPARDEVYRFMHDQVRPAIEAV
TAQLQEEGWKVSSRIDDGDMEISVDHGEQQGFRYQIVMRGYLTPSFAAQRFRNQRYYRAEVYLYEGSQDYDLVGYSREQI
INDIIDQYERHLQFLHLTR
>Mature_658_residues
SATAPHTLPVRTLRPVFVLAATVVCTFALLVSLFPLESGRVLLDAQTWASRNVGWYYLLAMTLYLVFVLATALSSYGNIK
LGADHDEPEFSYLSWAGMLFAAGISITLFFFCVSEPLTHYLQPPQGGTGSGEASARQAMQVLFLHWGLHGWGVFALAAMA
LAYFAFRHNLPLALRSALYPLIGKRINGPIGYTVDALGIVATVFGLGADMGFGVLHLNAGLSTLMDVPHTHWVQVALIVA
MMGAAIVVAVSGVEKGVRWMSDINMLLAIALLLFMLFAGPTQYLLNALMQNLGDYLGSVVNKSFDVYAYGGRADWLGNWT
VFYWAWWIGWAPFVGLFIARISRGRTIREFVLGVLLIPLGFTLAWLSIFGNSALDQLLHHGQAAWAQQAIDAPQTVLYSL
LQSYPWSRTVITVTVAISFVFFVTSADSGTVVLSTLSSHGGEPHDDGPRWLRVFWGVLTAVVTAGLLLAGSMEALKSAVV
LASLPFSAVLLLMAWGLSRALSEESQRKRAQLYSPSPLIGQSRHHGGWRQRLGQAMHFPARDEVYRFMHDQVRPAIEAVT
AQLQEEGWKVSSRIDDGDMEISVDHGEQQGFRYQIVMRGYLTPSFAAQRFRNQRYYRAEVYLYEGSQDYDLVGYSREQII
NDIIDQYERHLQFLHLTR

Specific function: High-affinity uptake of choline driven by a proton- motive force [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=667, Percent_Identity=45.4272863568216, Blast_Score=578, Evalue=1e-166,
Organism=Escherichia coli, GI1788102, Length=460, Percent_Identity=29.7826086956522, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786224, Length=468, Percent_Identity=25.4273504273504, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 73078; Mature: 72947

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATAPHTLPVRTLRPVFVLAATVVCTFALLVSLFPLESGRVLLDAQTWASRNVGWYYLL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCHHHHH
AMTLYLVFVLATALSSYGNIKLGADHDEPEFSYLSWAGMLFAAGISITLFFFCVSEPLTH
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLQPPQGGTGSGEASARQAMQVLFLHWGLHGWGVFALAAMALAYFAFRHNLPLALRSALY
HCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
PLIGKRINGPIGYTVDALGIVATVFGLGADMGFGVLHLNAGLSTLMDVPHTHWVQVALIV
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHCCCHHHHHHHHHH
AMMGAAIVVAVSGVEKGVRWMSDINMLLAIALLLFMLFAGPTQYLLNALMQNLGDYLGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VNKSFDVYAYGGRADWLGNWTVFYWAWWIGWAPFVGLFIARISRGRTIREFVLGVLLIPL
HCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GFTLAWLSIFGNSALDQLLHHGQAAWAQQAIDAPQTVLYSLLQSYPWSRTVITVTVAISF
HHHHHHHHHHCCHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
VFFVTSADSGTVVLSTLSSHGGEPHDDGPRWLRVFWGVLTAVVTAGLLLAGSMEALKSAV
HHHHCCCCCCCEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VLASLPFSAVLLLMAWGLSRALSEESQRKRAQLYSPSPLIGQSRHHGGWRQRLGQAMHFP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCC
ARDEVYRFMHDQVRPAIEAVTAQLQEEGWKVSSRIDDGDMEISVDHGEQQGFRYQIVMRG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEECCCCCCCCEEEEEEEC
YLTPSFAAQRFRNQRYYRAEVYLYEGSQDYDLVGYSREQIINDIIDQYERHLQFLHLTR
CCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SATAPHTLPVRTLRPVFVLAATVVCTFALLVSLFPLESGRVLLDAQTWASRNVGWYYLL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCHHHHH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CCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]