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The map label for this gene is acoR [H]

Identifier: 78046271

GI number: 78046271

Start: 812005

End: 813990

Strand: Reverse

Name: acoR [H]

Synonym: XCV0715

Alternate gene names: 78046271

Gene position: 813990-812005 (Counterclockwise)

Preceding gene: 78046272

Following gene: 78046262

Centisome position: 15.72

GC content: 69.49

Gene sequence:

>1986_bases
GTGTCGGAAGTGACTGTCGCCAACCTCCTGCAGGCCACGGCCGGGCCCTTGTCCGATGCCCAGGCCGAATCGGCGCTGCT
GGCGCGGATGCGCCGCTTTCGCCAGATCGAACCGCTGCCGCCGGCGCTGGCGCGCTCGTGGCAGCGCTGCCTGGACGAGT
ATGGGCTGAGTCCGGATGCCCCCCCGTTGCCGATGGTCCACGACGGCAGCGGGCTGCGCGAGCGCCAGCAGCGGCTCGAG
GAAGTGCTGCGCATCGCCAAGGTGGAGATGGAGAACCTCTACGAGCAGATCGCCGGCGGCGGCTATGCCGTGGTGTTCGC
CGACGCCGAGGCGACCTTGCTGCACAGCGTGCAGGACCCGGCACTGCTGCGCGAATTCCGCCAGACCGGGTTGTTTTGCG
GCGCCAGCTGGGCCGAGCGCTACCAGGGCACCAACGGCATCGGCACCTGCGCGGTGGAGCGCAGCGCGCTCGGCGTGCAC
CGCGGCGAGCATTACCTGGCCCGGCATCTGCCGCTGTCGTGCAGCGGTGCGCCGATCCTCGACCCGCACGGGCAATTGCT
GGCGGTGCTGGATGCGTCCACGCCGGACGCGCGCGACACCAAGCTGGTACAGCGCCACACCAGCGCGTTGGTGCGCATGT
CGGCGGCACAGATCGCGCGTTCGTATTTCCTGGAGCAGTACAGGCATGCGTGGATCTTGCGCTTCCACAGCCGCCCGGAG
TTCGCCGGCCTGTTGCACGAGGCGCTGATGGCGATCGGCGCCGACGGCTGCGTGCTGGCCGTCAACGAAGCGGCGCTGGA
ACAGCTCGGCAAGGGCGACCGCAGCCTGCTGGTCGGGCGCGACATCTCGCAGGTGATGCAGCTGGACTTCGACACCGTGG
AGCAGCGTGCGCGCAACGCTGCCAGCACGCTGTGGTCGATCCGCTGCGCCTGCCACGGGCGCCGTTTCTTCGCCCTGGCG
CAGCCGCCGCGCCGCAACGCGGTTGCTGGCGGCGCGCACGCCACCCCCGCCGACGATGGCGAGGCCGCTTACGCACGCGA
ACACGTCGGCTCCGATCCGCGCATGCGCCACAACCTGGACAACGCGCTGAAGCTGGTCGCGCATCGCGTGTCGATCCTGC
TGTGCGGCGCCACCGGCACCGGCAAGGAGGAGTTCGCCAAGGCGGTGCACCGCGGCTCGCCATGGGCGGCGCGGCCGTTC
GTGGCGGTGAACTGTGCGGCGATTCCCGAGGCGCTGATCGAGAGCGAACTGTTCGGCTACGCGCGCGGCGCGTTCACCGA
CGCCGCGCGCGAAGGCCGTCACGGCAAGCTGCTGCAGGCCAGCGGCGGCACCCTGTTCCTGGACGAAATCGGCGACATGC
CGCTGCCGCTGCAGACGCGGCTGCTGCGCGTGCTCGAAGAACAGAGCGTGACCCCGCTGGGCAGCGACCGGGCAATGCCG
CTGGAGCTGCACGTGATCAGCGCCAGCCACCGCGACCTGGCGCAGATGGTGGCCGCCGGCGAATTCCGCGAGGACCTGTA
CTACCGCCTCAACGGCGTGGTGCTGCATCTGCCGCCGCTACGCGAACGCAGCGACAAGGCCGAACTGATCCGCACCCTGT
TGCGCGAGGAAAACAGCGAGCGCAGCGTGCGCATCAGCGAAGATGCGCTGCACAAGCTGCTCAGCTACGCCTGGCCGGGC
AACCTGCGCCAATTGCGCAATGTGCTGCGCACGGCGGCCGTGCTGTGCAGTGACGAGGTGATTCGCCTGCCGAATCTGCC
GCAGGAGATCGTCGACGCGGGCAGCGCACCTTGCCTGGTCGATGCGCGCGCGGTCGCGGCCGACGATATGCCCGGCCGCG
TTGCATTGGATCAGGCCGAACGGCTGGTGCTGCAGCAACAACTCGAACGCCATCGCTGGAATGTCAGCCGCACCGCCGAT
GCCCTGGGCATCAGCCGTAACACCTTGTACCGCAAGTTGCGCAAGCACGGGCTGGAGACCGGGTGA

Upstream 100 bases:

>100_bases
AATCCGCATCCCCGGCGTTTGCTGCACCGCGGTTTGAGCCTCGCCCCGGTTTATGCGTCACTGCCGCTCTGGCCCCGGGT
AGGGACCGAGGAAGCGCCAC

Downstream 100 bases:

>100_bases
ATCGGGAATCGGGAATCGGGAATAGATAAAAGCAGCGCGCTGACGCTCTACGATTCCCGATTCCCGATTTCCCGCGATCA
AAGCGCCCAGCGCACGCCGA

Product: sigma-54-dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MSEVTVANLLQATAGPLSDAQAESALLARMRRFRQIEPLPPALARSWQRCLDEYGLSPDAPPLPMVHDGSGLRERQQRLE
EVLRIAKVEMENLYEQIAGGGYAVVFADAEATLLHSVQDPALLREFRQTGLFCGASWAERYQGTNGIGTCAVERSALGVH
RGEHYLARHLPLSCSGAPILDPHGQLLAVLDASTPDARDTKLVQRHTSALVRMSAAQIARSYFLEQYRHAWILRFHSRPE
FAGLLHEALMAIGADGCVLAVNEAALEQLGKGDRSLLVGRDISQVMQLDFDTVEQRARNAASTLWSIRCACHGRRFFALA
QPPRRNAVAGGAHATPADDGEAAYAREHVGSDPRMRHNLDNALKLVAHRVSILLCGATGTGKEEFAKAVHRGSPWAARPF
VAVNCAAIPEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQTRLLRVLEEQSVTPLGSDRAMP
LELHVISASHRDLAQMVAAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENSERSVRISEDALHKLLSYAWPG
NLRQLRNVLRTAAVLCSDEVIRLPNLPQEIVDAGSAPCLVDARAVAADDMPGRVALDQAERLVLQQQLERHRWNVSRTAD
ALGISRNTLYRKLRKHGLETG

Sequences:

>Translated_661_residues
MSEVTVANLLQATAGPLSDAQAESALLARMRRFRQIEPLPPALARSWQRCLDEYGLSPDAPPLPMVHDGSGLRERQQRLE
EVLRIAKVEMENLYEQIAGGGYAVVFADAEATLLHSVQDPALLREFRQTGLFCGASWAERYQGTNGIGTCAVERSALGVH
RGEHYLARHLPLSCSGAPILDPHGQLLAVLDASTPDARDTKLVQRHTSALVRMSAAQIARSYFLEQYRHAWILRFHSRPE
FAGLLHEALMAIGADGCVLAVNEAALEQLGKGDRSLLVGRDISQVMQLDFDTVEQRARNAASTLWSIRCACHGRRFFALA
QPPRRNAVAGGAHATPADDGEAAYAREHVGSDPRMRHNLDNALKLVAHRVSILLCGATGTGKEEFAKAVHRGSPWAARPF
VAVNCAAIPEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQTRLLRVLEEQSVTPLGSDRAMP
LELHVISASHRDLAQMVAAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENSERSVRISEDALHKLLSYAWPG
NLRQLRNVLRTAAVLCSDEVIRLPNLPQEIVDAGSAPCLVDARAVAADDMPGRVALDQAERLVLQQQLERHRWNVSRTAD
ALGISRNTLYRKLRKHGLETG
>Mature_660_residues
SEVTVANLLQATAGPLSDAQAESALLARMRRFRQIEPLPPALARSWQRCLDEYGLSPDAPPLPMVHDGSGLRERQQRLEE
VLRIAKVEMENLYEQIAGGGYAVVFADAEATLLHSVQDPALLREFRQTGLFCGASWAERYQGTNGIGTCAVERSALGVHR
GEHYLARHLPLSCSGAPILDPHGQLLAVLDASTPDARDTKLVQRHTSALVRMSAAQIARSYFLEQYRHAWILRFHSRPEF
AGLLHEALMAIGADGCVLAVNEAALEQLGKGDRSLLVGRDISQVMQLDFDTVEQRARNAASTLWSIRCACHGRRFFALAQ
PPRRNAVAGGAHATPADDGEAAYAREHVGSDPRMRHNLDNALKLVAHRVSILLCGATGTGKEEFAKAVHRGSPWAARPFV
AVNCAAIPEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQTRLLRVLEEQSVTPLGSDRAMPL
ELHVISASHRDLAQMVAAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENSERSVRISEDALHKLLSYAWPGN
LRQLRNVLRTAAVLCSDEVIRLPNLPQEIVDAGSAPCLVDARAVAADDMPGRVALDQAERLVLQQQLERHRWNVSRTADA
LGISRNTLYRKLRKHGLETG

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=316, Percent_Identity=44.620253164557, Blast_Score=246, Evalue=5e-66,
Organism=Escherichia coli, GI1789233, Length=297, Percent_Identity=43.0976430976431, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI1788550, Length=317, Percent_Identity=38.4858044164038, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1790437, Length=311, Percent_Identity=39.5498392282958, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=40.0602409638554, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI1786524, Length=328, Percent_Identity=41.7682926829268, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87082117, Length=299, Percent_Identity=40.8026755852843, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787583, Length=318, Percent_Identity=37.7358490566038, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1789087, Length=296, Percent_Identity=38.8513513513513, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI87082152, Length=258, Percent_Identity=43.0232558139535, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI87081858, Length=647, Percent_Identity=25.0386398763524, Blast_Score=176, Evalue=5e-45,
Organism=Escherichia coli, GI87081872, Length=299, Percent_Identity=35.4515050167224, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1789828, Length=256, Percent_Identity=36.71875, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72738; Mature: 72607

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVTVANLLQATAGPLSDAQAESALLARMRRFRQIEPLPPALARSWQRCLDEYGLSPDA
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCC
PPLPMVHDGSGLRERQQRLEEVLRIAKVEMENLYEQIAGGGYAVVFADAEATLLHSVQDP
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCH
ALLREFRQTGLFCGASWAERYQGTNGIGTCAVERSALGVHRGEHYLARHLPLSCSGAPIL
HHHHHHHHCCCCCCCHHHHHHCCCCCCEEHEEHHHHHHHHCCHHHHHHCCCCCCCCCCCC
DPHGQLLAVLDASTPDARDTKLVQRHTSALVRMSAAQIARSYFLEQYRHAWILRFHSRPE
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCH
FAGLLHEALMAIGADGCVLAVNEAALEQLGKGDRSLLVGRDISQVMQLDFDTVEQRARNA
HHHHHHHHHHHHCCCCCEEEECHHHHHHHCCCCCEEEECCCHHHHHHCCHHHHHHHHHHH
ASTLWSIRCACHGRRFFALAQPPRRNAVAGGAHATPADDGEAAYAREHVGSDPRMRHNLD
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHH
NALKLVAHRVSILLCGATGTGKEEFAKAVHRGSPWAARPFVAVNCAAIPEALIESELFGY
HHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
ARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQTRLLRVLEEQSVTPLGSDRAMP
HHHHHHHHHHCCCCCCEEECCCCEEEHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCE
LELHVISASHRDLAQMVAAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENSE
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHCCCCC
RSVRISEDALHKLLSYAWPGNLRQLRNVLRTAAVLCSDEVIRLPNLPQEIVDAGSAPCLV
CCEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCEEE
DARAVAADDMPGRVALDQAERLVLQQQLERHRWNVSRTADALGISRNTLYRKLRKHGLET
EHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCC
G
C
>Mature Secondary Structure 
SEVTVANLLQATAGPLSDAQAESALLARMRRFRQIEPLPPALARSWQRCLDEYGLSPDA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCC
PPLPMVHDGSGLRERQQRLEEVLRIAKVEMENLYEQIAGGGYAVVFADAEATLLHSVQDP
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCH
ALLREFRQTGLFCGASWAERYQGTNGIGTCAVERSALGVHRGEHYLARHLPLSCSGAPIL
HHHHHHHHCCCCCCCHHHHHHCCCCCCEEHEEHHHHHHHHCCHHHHHHCCCCCCCCCCCC
DPHGQLLAVLDASTPDARDTKLVQRHTSALVRMSAAQIARSYFLEQYRHAWILRFHSRPE
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCH
FAGLLHEALMAIGADGCVLAVNEAALEQLGKGDRSLLVGRDISQVMQLDFDTVEQRARNA
HHHHHHHHHHHHCCCCCEEEECHHHHHHHCCCCCEEEECCCHHHHHHCCHHHHHHHHHHH
ASTLWSIRCACHGRRFFALAQPPRRNAVAGGAHATPADDGEAAYAREHVGSDPRMRHNLD
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHH
NALKLVAHRVSILLCGATGTGKEEFAKAVHRGSPWAARPFVAVNCAAIPEALIESELFGY
HHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
ARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQTRLLRVLEEQSVTPLGSDRAMP
HHHHHHHHHHCCCCCCEEECCCCEEEHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCE
LELHVISASHRDLAQMVAAGEFREDLYYRLNGVVLHLPPLRERSDKAELIRTLLREENSE
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHCCCCC
RSVRISEDALHKLLSYAWPGNLRQLRNVLRTAAVLCSDEVIRLPNLPQEIVDAGSAPCLV
CCEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCEEE
DARAVAADDMPGRVALDQAERLVLQQQLERHRWNVSRTADALGISRNTLYRKLRKHGLET
EHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]