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The map label for this gene is dsbD [H]

Identifier: 78046123

GI number: 78046123

Start: 634575

End: 636893

Strand: Reverse

Name: dsbD [H]

Synonym: XCV0567

Alternate gene names: 78046123

Gene position: 636893-634575 (Counterclockwise)

Preceding gene: 78046124

Following gene: 78046122

Centisome position: 12.3

GC content: 70.94

Gene sequence:

>2319_bases
ATGAAGTCTCTGTCCCGCTGGATCGCCCGCTGCGCGCTCTTGGCCGCCCCCTTGCTCGCCGCGCCGCTGGCGGTACTGGC
GCCCGCCCCCGCGCAGGCCGCCGTAACCGAAGCCGACCTGCTGCCGGTGGACCAGGCCTTCGCGCTGAGCGCCACCGCCG
ACAGCCGCGACCGCATCGCGCTGCACTGGAAGATCGCACCGGGCTACTACCTGTATCGCCACCGCATCAGCGTCAAGGCC
GGAAAGGGGTTTGCCGCGGGCGAACTGGCGCTGCCGGAAGGCGAGAGCAAGCACGACGAGTTCTTCGGCCAGGTGCAGAC
CTACCGCAAGCAACTGCAGGCCACCCTGGCCGGCAAGGCCGACCCGGCAGTGCAGACCGCCGTCCTGCAGGTGCAGTACC
AGGGCTGCGCCGATGCCGGCGTGTGCTATCCACCGCAGCGGCGCGAAATCCGCCTCGACCTGCCCGCGGCCGATGCCACC
GGGGCGCAGGCCACCGCCGCGCCACGCGAAAACCTGGGCGCGCTGGTGCCACGCAACGCCGCCGCCCCGCGCCTGTTCGG
CGCCCCCGGCCAGACCGCCGGGGTGGACGCATTGCCGCTGCCGGCCGAGCAGGCGTTCAATTTCGAAGCCATCGTCGGCG
ACGGCAACAGCCTGCTGCTGCGCTTCACCCCGGCGCCGGGCTATTACATCTACCGCGACCGCACCTCGCTGGCCCTGGAA
GGCGCCAACGGCGTGCGCACCGGGCTGCCGCGCTGGCCGCAAGGCAAGGCCCACCGCGACGAACACTTCGGCGATGTGGT
GGTGTATTTCGACCAGGCCGAAGTGACCTTGCCGCTGCTGCGCGACCACCCTGACCCGGCCCACGTGACCCTGGTGGCCA
CCTTCCAGGGCTGCCAGACCGACGGGATCTGCTATCCGCCGATGACCCGCCGCGTCGCCCTGGATGTACCGGCCGGAACC
GTGTCGCCGCAGAACCAGGCGCAGGCCGCGCCGTTGATGATTTCGCCGCTGGCCGCCGGCCAGGCACCGGTCGAGCCGGC
GCCGGCCGCCAGCACGGCCGTCCCGGTCGCCGATGCCTCGGCCGGCAACCCGGAGCGCACGCCGCCGCCGCATACCGACA
AGGGCCTGCTGGGCATGCTGGTGCTGGCCCTGCTTGGTGGGTTGGTGCTGAACCTGATGCCCTGCGTGCTGCCGATCCTG
TCGCTGAAGGTGCTGGGCCTGGCGCACAGCGGCGAGAGCCGCAGCCACGCGCGCAGCCATGCCATCTGGTATTCGCTGGG
CGTGCTGGTGTCCTTTGCCGCCATCGGTGGCCTGGTGATCGGCTTGCGCGCCGCCGGGCAGGCCGCCGGCTGGGGCTTCC
AGCTGCAGCAGCCGTGGTTCGTCGCGGCGCTGGCGTATCTGATGTTCGCGGTGGGGCTGAGCCTGTCGGGCGTGTTCACC
TTGGGCACCAACCTGGGCGGCATCGGCCAGTCGCTGGCCGCGCGCAACGGGCCGCTGGGCGACTTCTTCACCGGCGTGCT
GGCCTGCGTGGTCGCCAGCCCCTGCATCGCGCCGTTCATGGGCACGGCACTGGCCTACGCCTTCACCGCGCCCGCGCTGC
TGGCGATGCTGGTATTCCTGGTGCTGGGCCTGGGCCTGGCGCTGCCGTTCCTGCTGATCGGCTTCGTGCCTTCGCTGGCG
CGGCGCCTGCCCACCCCCGGGGCGTGGATGGAAACGCTCAAGCAGGTGCTGGCGTTCCCCATGTATCTCACCGCGATCTG
GCTGCTGTGGGTATTAGGCAAGCAGCGCGGCGTGGATGCGCTGGCCTTGATGCTGGTCGGCGCCACCCTGCTGGCCCTGG
GGCTGTGGTGCTTCGAGCGCAGCCGCTGGAAGAGCCACCGCCTGGGCATGGGCCTGGCCACGACGATGCTGGTACTGGCG
CTGGTGCCGGTGGTCGCGGTCACGCGCCTGAGCCTGCCAGCGGCCACCGCGGCCGAGGGCGTGGTGGCGTTCTCGCCGCA
GTTGCTGGACCGCCTGCGTGCCGACAACCGCGTGGTCTTCGTCAACATGACCGCCGATTGGTGCGTGACCTGCAAGGCCA
ACGAAAAGAACGTGCTGAGCAGCGCCGAATTCCGCGACGCGTTGCGCCGCGTCGATGCGGTCTACATGAAGGGCGACTGG
ACCAATGTCGACCCCGCCATCAGCACCTTCCTCGACCAGCACCAGGCCGTCGGCGTGCCGCTGTACGTGGTCTACGGCCC
CGGCGCCCCGCCGGCGATCCTGCCGACCGTGCTGACCGGCGCGATTACCGAAGACGCCTTGCTGCGCGCTGCGCGGTAA

Upstream 100 bases:

>100_bases
CGTATGAACTGCCGGAGGCGGTCGCTGTCCAAGCCAGCGCCGGGCTGCCGGCATATCTCGATTGGGTCCGGGCCGAAACC
CGCAAGGAATTCTGACGTCC

Downstream 100 bases:

>100_bases
GGCGCGCCTTCGCTGCGGCTGGTGGCCTGGGCGGCCGTCTGTTGGCGGGCCAGGCCGAAGATTTTGCGAACCGTGTAGGC
CGACACCCGTGCCATGGGCG

Product: putative C-type cytochrome biogenesis protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 772; Mature: 772

Protein sequence:

>772_residues
MKSLSRWIARCALLAAPLLAAPLAVLAPAPAQAAVTEADLLPVDQAFALSATADSRDRIALHWKIAPGYYLYRHRISVKA
GKGFAAGELALPEGESKHDEFFGQVQTYRKQLQATLAGKADPAVQTAVLQVQYQGCADAGVCYPPQRREIRLDLPAADAT
GAQATAAPRENLGALVPRNAAAPRLFGAPGQTAGVDALPLPAEQAFNFEAIVGDGNSLLLRFTPAPGYYIYRDRTSLALE
GANGVRTGLPRWPQGKAHRDEHFGDVVVYFDQAEVTLPLLRDHPDPAHVTLVATFQGCQTDGICYPPMTRRVALDVPAGT
VSPQNQAQAAPLMISPLAAGQAPVEPAPAASTAVPVADASAGNPERTPPPHTDKGLLGMLVLALLGGLVLNLMPCVLPIL
SLKVLGLAHSGESRSHARSHAIWYSLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFT
LGTNLGGIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPALLAMLVFLVLGLGLALPFLLIGFVPSLA
RRLPTPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALMLVGATLLALGLWCFERSRWKSHRLGMGLATTMLVLA
LVPVVAVTRLSLPAATAAEGVVAFSPQLLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSAEFRDALRRVDAVYMKGDW
TNVDPAISTFLDQHQAVGVPLYVVYGPGAPPAILPTVLTGAITEDALLRAAR

Sequences:

>Translated_772_residues
MKSLSRWIARCALLAAPLLAAPLAVLAPAPAQAAVTEADLLPVDQAFALSATADSRDRIALHWKIAPGYYLYRHRISVKA
GKGFAAGELALPEGESKHDEFFGQVQTYRKQLQATLAGKADPAVQTAVLQVQYQGCADAGVCYPPQRREIRLDLPAADAT
GAQATAAPRENLGALVPRNAAAPRLFGAPGQTAGVDALPLPAEQAFNFEAIVGDGNSLLLRFTPAPGYYIYRDRTSLALE
GANGVRTGLPRWPQGKAHRDEHFGDVVVYFDQAEVTLPLLRDHPDPAHVTLVATFQGCQTDGICYPPMTRRVALDVPAGT
VSPQNQAQAAPLMISPLAAGQAPVEPAPAASTAVPVADASAGNPERTPPPHTDKGLLGMLVLALLGGLVLNLMPCVLPIL
SLKVLGLAHSGESRSHARSHAIWYSLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFT
LGTNLGGIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPALLAMLVFLVLGLGLALPFLLIGFVPSLA
RRLPTPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALMLVGATLLALGLWCFERSRWKSHRLGMGLATTMLVLA
LVPVVAVTRLSLPAATAAEGVVAFSPQLLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSAEFRDALRRVDAVYMKGDW
TNVDPAISTFLDQHQAVGVPLYVVYGPGAPPAILPTVLTGAITEDALLRAAR
>Mature_772_residues
MKSLSRWIARCALLAAPLLAAPLAVLAPAPAQAAVTEADLLPVDQAFALSATADSRDRIALHWKIAPGYYLYRHRISVKA
GKGFAAGELALPEGESKHDEFFGQVQTYRKQLQATLAGKADPAVQTAVLQVQYQGCADAGVCYPPQRREIRLDLPAADAT
GAQATAAPRENLGALVPRNAAAPRLFGAPGQTAGVDALPLPAEQAFNFEAIVGDGNSLLLRFTPAPGYYIYRDRTSLALE
GANGVRTGLPRWPQGKAHRDEHFGDVVVYFDQAEVTLPLLRDHPDPAHVTLVATFQGCQTDGICYPPMTRRVALDVPAGT
VSPQNQAQAAPLMISPLAAGQAPVEPAPAASTAVPVADASAGNPERTPPPHTDKGLLGMLVLALLGGLVLNLMPCVLPIL
SLKVLGLAHSGESRSHARSHAIWYSLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFT
LGTNLGGIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPALLAMLVFLVLGLGLALPFLLIGFVPSLA
RRLPTPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDALALMLVGATLLALGLWCFERSRWKSHRLGMGLATTMLVLA
LVPVVAVTRLSLPAATAAEGVVAFSPQLLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSAEFRDALRRVDAVYMKGDW
TNVDPAISTFLDQHQAVGVPLYVVYGPGAPPAILPTVLTGAITEDALLRAAR

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=583, Percent_Identity=28.1303602058319, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 81512; Mature: 81512

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLSRWIARCALLAAPLLAAPLAVLAPAPAQAAVTEADLLPVDQAFALSATADSRDRIA
CCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCCCCHHEEEECCCCCCEEE
LHWKIAPGYYLYRHRISVKAGKGFAAGELALPEGESKHDEFFGQVQTYRKQLQATLAGKA
EEEEECCCEEEEEEEEEEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DPAVQTAVLQVQYQGCADAGVCYPPQRREIRLDLPAADATGAQATAAPRENLGALVPRNA
CHHHHEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCC
AAPRLFGAPGQTAGVDALPLPAEQAFNFEAIVGDGNSLLLRFTPAPGYYIYRDRTSLALE
CCCCEECCCCCCCCCCCCCCCHHHCCCEEEEEECCCEEEEEEECCCCEEEEECCCEEEEE
GANGVRTGLPRWPQGKAHRDEHFGDVVVYFDQAEVTLPLLRDHPDPAHVTLVATFQGCQT
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHCCCCCCEEEEEEEECCCCC
DGICYPPMTRRVALDVPAGTVSPQNQAQAAPLMISPLAAGQAPVEPAPAASTAVPVADAS
CCEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
AGNPERTPPPHTDKGLLGMLVLALLGGLVLNLMPCVLPILSLKVLGLAHSGESRSHARSH
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHH
AIWYSLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
LGTNLGGIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPALLAMLVFL
ECCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGLGLALPFLLIGFVPSLARRLPTPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LALMLVGATLLALGLWCFERSRWKSHRLGMGLATTMLVLALVPVVAVTRLSLPAATAAEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCC
VVAFSPQLLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSAEFRDALRRVDAVYMKGDW
EEEECHHHHHHHCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECCC
TNVDPAISTFLDQHQAVGVPLYVVYGPGAPPAILPTVLTGAITEDALLRAAR
CCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSLSRWIARCALLAAPLLAAPLAVLAPAPAQAAVTEADLLPVDQAFALSATADSRDRIA
CCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCCCCHHEEEECCCCCCEEE
LHWKIAPGYYLYRHRISVKAGKGFAAGELALPEGESKHDEFFGQVQTYRKQLQATLAGKA
EEEEECCCEEEEEEEEEEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DPAVQTAVLQVQYQGCADAGVCYPPQRREIRLDLPAADATGAQATAAPRENLGALVPRNA
CHHHHEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCC
AAPRLFGAPGQTAGVDALPLPAEQAFNFEAIVGDGNSLLLRFTPAPGYYIYRDRTSLALE
CCCCEECCCCCCCCCCCCCCCHHHCCCEEEEEECCCEEEEEEECCCCEEEEECCCEEEEE
GANGVRTGLPRWPQGKAHRDEHFGDVVVYFDQAEVTLPLLRDHPDPAHVTLVATFQGCQT
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHCCCCCCEEEEEEEECCCCC
DGICYPPMTRRVALDVPAGTVSPQNQAQAAPLMISPLAAGQAPVEPAPAASTAVPVADAS
CCEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
AGNPERTPPPHTDKGLLGMLVLALLGGLVLNLMPCVLPILSLKVLGLAHSGESRSHARSH
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHH
AIWYSLGVLVSFAAIGGLVIGLRAAGQAAGWGFQLQQPWFVAALAYLMFAVGLSLSGVFT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
LGTNLGGIGQSLAARNGPLGDFFTGVLACVVASPCIAPFMGTALAYAFTAPALLAMLVFL
ECCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGLGLALPFLLIGFVPSLARRLPTPGAWMETLKQVLAFPMYLTAIWLLWVLGKQRGVDA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LALMLVGATLLALGLWCFERSRWKSHRLGMGLATTMLVLALVPVVAVTRLSLPAATAAEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCC
VVAFSPQLLDRLRADNRVVFVNMTADWCVTCKANEKNVLSSAEFRDALRRVDAVYMKGDW
EEEECHHHHHHHCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECCC
TNVDPAISTFLDQHQAVGVPLYVVYGPGAPPAILPTVLTGAITEDALLRAAR
CCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]