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The map label for this gene is hemH

Identifier: 78046056

GI number: 78046056

Start: 565808

End: 566734

Strand: Reverse

Name: hemH

Synonym: XCV0500

Alternate gene names: 78046056

Gene position: 566734-565808 (Counterclockwise)

Preceding gene: 78046075

Following gene: 78046055

Centisome position: 10.94

GC content: 63.21

Gene sequence:

>927_bases
GTGTCGACCACGCTGTTGCAATCCGATCTGCCCGGCCTGCCGTTGCGTCACCGTGGCAAGGTCCGCGATGTCTTCGATCT
TCCCCGCGACCGCCTGCCCGCCGATGCGCCCCCGGGCGACTATCTGTTGATGGTGGCCACCGACCGCCTGTCCGCGTTCG
ACGTGGTGCTGCCCGACCCGATTCCCGGCAAGGGCGAGATGCTGTGCCAGGTATCCAACTTCTGGTTTCACAAGACCGAA
CACCTGATGCCCAACCACCTGATGGACATCCGCGTGGAGCAGGTATTGCCCGAGGGTGTCGATCCGGCCTTGTACGCCAA
ACGCGCCGTGGTCACGCGCAAGCTCAAGCCGGTGCCGGTGGAAGCCATCGCCCGCGGCTATGTGATCGGCAGCGGCTGGA
AGGATTACCAGCGCACCGGCAAGATCAGCGGCATCGAATTGCCCGACGGCCTGCGTCAGGCCGAGAAACTGCCCGAGCCG
ATTTTCACTCCTTCGACCAAGGCAGCGGTTGGCGACCACGACGAAAACATCGACTTCGATGCAATGGTCAAGACGGTCGG
CGCCGAGCTGGCCGAACGCGTGCGCGATGCCACCTTGCGCATCTACCGGTTCGCAGCCGATTTTGCTGCCGAACGCGGCA
TATTACTGGCCGATACCAAGTTCGAATTCGGTACCGATGCCGATGGCCGCCTGTACATCATGGACGAGATGCTGACTCCG
GATTCCTCGCGTTATTGGCCGGCCGACCAATACGAACCGGGCACCAGCCCGCCGAGCTACGACAAGCAGTTTGTGCGCGA
TTATCTGGAAACCCTGGACTGGGGCAAGACCGCGCCCGGCCCGCGCCTGCCGGCCGACGTCATCGATCGCACGCGTGCGA
AATATGCCGAAGCGCTGCAGCGGCTGGCGGACATTTCGGTGGATTGA

Upstream 100 bases:

>100_bases
CGGGAGGCGGCGAAGCGCCGTACACTACGCGGCCCGCTGCCTACCCGCGGGCCCGCCGGGTCCCGGGGACAGCGTCATAG
CGACGTCCTTAGGAGTGCCT

Downstream 100 bases:

>100_bases
TTGCACGCACCCGGTGAGGGGCGAGGCGGCGAAGTACGCAGACGCCTATGCCTGCGAGCGCCGACATTCTCGGCGCTTCG
ATTCCTCGACTACCGACTGA

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSTTLLQSDLPGLPLRHRGKVRDVFDLPRDRLPADAPPGDYLLMVATDRLSAFDVVLPDPIPGKGEMLCQVSNFWFHKTE
HLMPNHLMDIRVEQVLPEGVDPALYAKRAVVTRKLKPVPVEAIARGYVIGSGWKDYQRTGKISGIELPDGLRQAEKLPEP
IFTPSTKAAVGDHDENIDFDAMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEMLTP
DSSRYWPADQYEPGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIDRTRAKYAEALQRLADISVD

Sequences:

>Translated_308_residues
MSTTLLQSDLPGLPLRHRGKVRDVFDLPRDRLPADAPPGDYLLMVATDRLSAFDVVLPDPIPGKGEMLCQVSNFWFHKTE
HLMPNHLMDIRVEQVLPEGVDPALYAKRAVVTRKLKPVPVEAIARGYVIGSGWKDYQRTGKISGIELPDGLRQAEKLPEP
IFTPSTKAAVGDHDENIDFDAMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEMLTP
DSSRYWPADQYEPGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIDRTRAKYAEALQRLADISVD
>Mature_307_residues
STTLLQSDLPGLPLRHRGKVRDVFDLPRDRLPADAPPGDYLLMVATDRLSAFDVVLPDPIPGKGEMLCQVSNFWFHKTEH
LMPNHLMDIRVEQVLPEGVDPALYAKRAVVTRKLKPVPVEAIARGYVIGSGWKDYQRTGKISGIELPDGLRQAEKLPEPI
FTPSTKAAVGDHDENIDFDAMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEMLTPD
SSRYWPADQYEPGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIDRTRAKYAEALQRLADISVD

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=310, Percent_Identity=43.2258064516129, Blast_Score=254, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PUR7_XANC5 (Q3BYD2)

Other databases:

- EMBL:   AM039952
- RefSeq:   YP_362231.1
- HSSP:   P27616
- ProteinModelPortal:   Q3BYD2
- SMR:   Q3BYD2
- STRING:   Q3BYD2
- GeneID:   3732949
- GenomeReviews:   AM039952_GR
- KEGG:   xcv:XCV0500
- NMPDR:   fig|316273.3.peg.755
- eggNOG:   COG0152
- HOGENOM:   HBG555040
- OMA:   LTLMDEV
- ProtClustDB:   PRK13961
- HAMAP:   MF_00137
- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236
- Gene3D:   G3DSA:3.30.470.20
- PANTHER:   PTHR11609
- TIGRFAMs:   TIGR00081

Pfam domain/function: PF01259 SAICAR_synt

EC number: =6.3.2.6

Molecular weight: Translated: 34484; Mature: 34352

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS01057 SAICAR_SYNTHETASE_1; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTLLQSDLPGLPLRHRGKVRDVFDLPRDRLPADAPPGDYLLMVATDRLSAFDVVLPDP
CCCCCCCCCCCCCCCCCCCCCHHHHHCCHHCCCCCCCCCCEEEEEECCCCCEEEEECCCC
IPGKGEMLCQVSNFWFHKTEHLMPNHLMDIRVEQVLPEGVDPALYAKRAVVTRKLKPVPV
CCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCH
EAIARGYVIGSGWKDYQRTGKISGIELPDGLRQAEKLPEPIFTPSTKAAVGDHDENIDFD
HHHHCCCEECCCCHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
AMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEMLTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCCC
DSSRYWPADQYEPGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIDRTRAKYAEALQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLADISVD
HHHHCCCC
>Mature Secondary Structure 
STTLLQSDLPGLPLRHRGKVRDVFDLPRDRLPADAPPGDYLLMVATDRLSAFDVVLPDP
CCCCCCCCCCCCCCCCCCCCHHHHHCCHHCCCCCCCCCCEEEEEECCCCCEEEEECCCC
IPGKGEMLCQVSNFWFHKTEHLMPNHLMDIRVEQVLPEGVDPALYAKRAVVTRKLKPVPV
CCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCH
EAIARGYVIGSGWKDYQRTGKISGIELPDGLRQAEKLPEPIFTPSTKAAVGDHDENIDFD
HHHHCCCEECCCCHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
AMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEMLTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCCC
DSSRYWPADQYEPGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIDRTRAKYAEALQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLADISVD
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA