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The map label for this gene is fabG [H]

Identifier: 78045955

GI number: 78045955

Start: 452395

End: 453177

Strand: Reverse

Name: fabG [H]

Synonym: XCV0399

Alternate gene names: 78045955

Gene position: 453177-452395 (Counterclockwise)

Preceding gene: 78045956

Following gene: 78045954

Centisome position: 8.75

GC content: 69.6

Gene sequence:

>783_bases
ATGGATCTGGGAATCGCTGGCCGCTGGGCGTTGGTCTGCGCCGCAAGCAAAGGGCTGGGTTTGGGCTGCGCACGTGCATT
GGCCGGCGAAGGCGCCAATGTGGTGATCGCCGCGCGCGGCCGTGAGGCACTGGAGCACGCCGCCGACGCCTTGCGCGCAC
TGCCCGGCGCTGGCCAGGTGCGCAGCGTGGTTGCCGATATCGCCACGCCGGAAGGACGCAGCGCCGCACTTGCGGCCTGT
CCGCAGGTCGACATCCTGATCAACAACGCGGGCGGCCCGCCGCCGGGCGATTTCCGCCAGTGGGAACGCGCCGACTGGTT
GCGCGCGCTGGACGCCAACATGCTGGCGCCGATCGAACTGATCCGCGCCACCGTCGATGGCATGCGCGCCCGCCGCTTCG
GCCGCATCGTCAACATCACCTCCAGCGCGGTGAAGGCGCCGATCGACATCCTCGGCCTGTCCAATGGCGCGCGCGCCGGC
CTGACCGGTTTCGTCGCCGGGCTCGCGCGCAGCACCGTGGCCGACAACGTCACCATCAACAACCTGCTGCCTGGGCAGTT
CGTCACCGACCGCTTGCGCGGCAACTTCGCCGCCATCGCGCAGCAACAGGGCAGCAGCGCCGACGAGGTCGCCGAACGCA
AGCGCGCGGGCATTCCGGCGGCGCGTTTTGGCGAGCCGGACGAGTTCGGCGCGGCCTGCGCCTTTCTGTGCAGCGCGCAG
GCCGGCTATATCACCGGACAGAATCTGTTGATCGATGGCGGCAGCTATCCCGGCACGTTCTAG

Upstream 100 bases:

>100_bases
TCATGCAGATCAGGTGAGCGAGGCGCTGCAACGCTTCGTTGCGTCCGTGCCATGAGCCGATCGTCGATCATGCGACATCG
CTGATCGAGGGACATCTCGC

Downstream 100 bases:

>100_bases
CGCGGCGCCTTGCACGCCCGATCGATTCCCTCCGCCCCTGCCAGGGGCGACAATAGCCTTGCCATGACCAGTACTTTCGA
TCCCCGCCACGTCCGGCGCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MDLGIAGRWALVCAASKGLGLGCARALAGEGANVVIAARGREALEHAADALRALPGAGQVRSVVADIATPEGRSAALAAC
PQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIELIRATVDGMRARRFGRIVNITSSAVKAPIDILGLSNGARAG
LTGFVAGLARSTVADNVTINNLLPGQFVTDRLRGNFAAIAQQQGSSADEVAERKRAGIPAARFGEPDEFGAACAFLCSAQ
AGYITGQNLLIDGGSYPGTF

Sequences:

>Translated_260_residues
MDLGIAGRWALVCAASKGLGLGCARALAGEGANVVIAARGREALEHAADALRALPGAGQVRSVVADIATPEGRSAALAAC
PQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIELIRATVDGMRARRFGRIVNITSSAVKAPIDILGLSNGARAG
LTGFVAGLARSTVADNVTINNLLPGQFVTDRLRGNFAAIAQQQGSSADEVAERKRAGIPAARFGEPDEFGAACAFLCSAQ
AGYITGQNLLIDGGSYPGTF
>Mature_260_residues
MDLGIAGRWALVCAASKGLGLGCARALAGEGANVVIAARGREALEHAADALRALPGAGQVRSVVADIATPEGRSAALAAC
PQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIELIRATVDGMRARRFGRIVNITSSAVKAPIDILGLSNGARAG
LTGFVAGLARSTVADNVTINNLLPGQFVTDRLRGNFAAIAQQQGSSADEVAERKRAGIPAARFGEPDEFGAACAFLCSAQ
AGYITGQNLLIDGGSYPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=29.1828793774319, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=28.7937743190661, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=29.5719844357977, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=26.8482490272374, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI66933014, Length=231, Percent_Identity=25.5411255411255, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=26.8482490272374, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=30.2083333333333, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40254992, Length=258, Percent_Identity=26.7441860465116, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787335, Length=264, Percent_Identity=31.8181818181818, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=28.4046692607004, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=32.183908045977, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=28.0769230769231, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=27.6679841897233, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=24.031007751938, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=26.2357414448669, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789208, Length=270, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=30.7392996108949, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=28.2945736434109, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=29.0076335877863, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=27.027027027027, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=32.0754716981132, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=29.1828793774319, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=27.4725274725275, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=27.8625954198473, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=27.0992366412214, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=26.7924528301887, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=28.5171102661597, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=28.7822878228782, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=29.368029739777, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=27.027027027027, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=27.1375464684015, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=27.7566539923954, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=28.3400809716599, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=257, Percent_Identity=26.4591439688716, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=272, Percent_Identity=25.3676470588235, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=26.0377358490566, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=25.8426966292135, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=28.2352941176471, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=27.6264591439689, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=30.1158301158301, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=28.0769230769231, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=27.1317829457364, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=266, Percent_Identity=25.5639097744361, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=25, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26761; Mature: 26761

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIAGRWALVCAASKGLGLGCARALAGEGANVVIAARGREALEHAADALRALPGAGQV
CCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCHHH
RSVVADIATPEGRSAALAACPQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIEL
HHHHHHHCCCCCCCHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
IRATVDGMRARRFGRIVNITSSAVKAPIDILGLSNGARAGLTGFVAGLARSTVADNVTIN
HHHHHHHHHHHHHHHHEEECHHHHHCCHHEEECCCCCCHHHHHHHHHHHHHHHHCCCEEC
NLLPGQFVTDRLRGNFAAIAQQQGSSADEVAERKRAGIPAARFGEPDEFGAACAFLCSAQ
CCCCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCC
AGYITGQNLLIDGGSYPGTF
CCEEECCEEEEECCCCCCCC
>Mature Secondary Structure
MDLGIAGRWALVCAASKGLGLGCARALAGEGANVVIAARGREALEHAADALRALPGAGQV
CCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCHHH
RSVVADIATPEGRSAALAACPQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIEL
HHHHHHHCCCCCCCHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
IRATVDGMRARRFGRIVNITSSAVKAPIDILGLSNGARAGLTGFVAGLARSTVADNVTIN
HHHHHHHHHHHHHHHHEEECHHHHHCCHHEEECCCCCCHHHHHHHHHHHHHHHHCCCEEC
NLLPGQFVTDRLRGNFAAIAQQQGSSADEVAERKRAGIPAARFGEPDEFGAACAFLCSAQ
CCCCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCC
AGYITGQNLLIDGGSYPGTF
CCEEECCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]