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The map label for this gene is baeS [H]

Identifier: 78045891

GI number: 78045891

Start: 382247

End: 383626

Strand: Reverse

Name: baeS [H]

Synonym: XCV0335

Alternate gene names: 78045891

Gene position: 383626-382247 (Counterclockwise)

Preceding gene: 78045895

Following gene: 78045890

Centisome position: 7.41

GC content: 69.86

Gene sequence:

>1380_bases
ATGAAACTGGGTATCACCGCCAAGCTGTTTCTCGCCATCCTCGCCGCGTGCGTGGCAGTGCTGCTGATCAACGGCATCGC
GGTGCAGGCCTTCGTCAAACGCCAGTTCCTGGACTACCTCAACGAACAGGGCGTGGAGCGCATGCAAGAGACCTTGCCGC
GGGTCAGGGCCGAATACGCGCGGCACGGCAGCTGGGAGTTCGTGCGCGACAATCCCGATGCCTGGTTCGTCCTGATGCGC
CCGGAGCGTGGCCCCGGCCCGCCGCGCGAGGCACCGCCGATTTCCGACCAGACCGGCGCGGTGTTTCGCTTCGCGCTGCT
CGACCAGGACTACACGCCGGTGATTGGCAATCCGGATGTCGGCCGCCACGACATCCTGCGCCCGGTGGTGGTTGGCGGCC
GCACCGTCGGCTGGATGGCGATGCTGCCGTTCCAGAAGGCGCTGGCAGCGGCGGACGCGCGCTTCTACGCCGCCCAGCAA
CGCGCGTGGTGGGCGATCGGCGGCGCCTGCCTGCTGGTCGCCGCGCTGCTCGGCTGGCTGTTGTCGCGCACCTTGCTGCG
GCGCCTGCGTGGCCTGACCCAGGCCACCCACCTGCTCGCTGCGGGCGACTACGCCACCCGCATCGACGCCGCGGCGCGCG
ACGAACTGGGCCAGCTGGCGCGCGATTTCAACCTGCTGGCGCAAGCGTTGGAGCACAACGAACGCGCGCGGCGCGACTTC
ATGGCCGACATCTCGCACGAGCTGCGCACGCCGCTGGCGGTCCTGCGCGCCGAACTGGAAGCACTGCAGGACGGCATCCG
GCCGATGACACCCATCTCGCTGGGGTCGCTGCACCAGCAGGTCGGCCAGTTGGGCAAGCTGATCGAGGACCTGTACGACG
TGTCGCTGACCGATGTCGGTGCGCTGGCGTATCGGCGCGCTCCCGTCGATCTGGCGGTCATCCTGGCAACCGTGCTGGAC
GGCTTGCACGCGCGCTTTGCCGCCGCGCAGCTGCAGGTGCAGGCGCAGATCGATGCCGGCCCGCTGCAGCTGGACGGCGA
CGAGCGCCGTCTGCAGCAACTGCTGGGCAACCTGCTGGAAAACACGCTGCGCTACACCGACGCCGGTGGCACGGTGCAGG
TGCGCTGCGTGCGCCGCGGCGCGGTGCTGGAGCTGGTGGTCGAAGACAGCGCGCCAGGCGTGGATGCAGACAAGCGCGCG
CGGTTGTTCGAACGCTTCTACCGCACCGAGGCCTCACGCAATCGTGCCAGCGGCGGCGGCGGCCTGGGCCTGGCGATCTG
CCGCAACATCGCCGAGGCACACGGCGGCTCGATCCACGCCGAGGCTTCCGCACTGGGCGGGCTGCGCATGGTGCTGCGCT
TGCCGGCGCTGGCCGCATGA

Upstream 100 bases:

>100_bases
TGGAGATTGCCGGCCGCGGCGTCGATTCGCTTGATTTCCCCTGGCCCGACCCGGCTAATACGCAGCAGCTGCGGTTACCG
CGCTTCGCATCACCTCTTCG

Downstream 100 bases:

>100_bases
GCAGCGCGTCCCCGATCGGGCATGTGCTGATCGTCGAGGACGAACCGCGCCTGGCCGCGGTGTTGGGCGAGTACCTGCAC
GCGGCCGGCTATTCGCACGA

Product: two-component system sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKLGITAKLFLAILAACVAVLLINGIAVQAFVKRQFLDYLNEQGVERMQETLPRVRAEYARHGSWEFVRDNPDAWFVLMR
PERGPGPPREAPPISDQTGAVFRFALLDQDYTPVIGNPDVGRHDILRPVVVGGRTVGWMAMLPFQKALAAADARFYAAQQ
RAWWAIGGACLLVAALLGWLLSRTLLRRLRGLTQATHLLAAGDYATRIDAAARDELGQLARDFNLLAQALEHNERARRDF
MADISHELRTPLAVLRAELEALQDGIRPMTPISLGSLHQQVGQLGKLIEDLYDVSLTDVGALAYRRAPVDLAVILATVLD
GLHARFAAAQLQVQAQIDAGPLQLDGDERRLQQLLGNLLENTLRYTDAGGTVQVRCVRRGAVLELVVEDSAPGVDADKRA
RLFERFYRTEASRNRASGGGGLGLAICRNIAEAHGGSIHAEASALGGLRMVLRLPALAA

Sequences:

>Translated_459_residues
MKLGITAKLFLAILAACVAVLLINGIAVQAFVKRQFLDYLNEQGVERMQETLPRVRAEYARHGSWEFVRDNPDAWFVLMR
PERGPGPPREAPPISDQTGAVFRFALLDQDYTPVIGNPDVGRHDILRPVVVGGRTVGWMAMLPFQKALAAADARFYAAQQ
RAWWAIGGACLLVAALLGWLLSRTLLRRLRGLTQATHLLAAGDYATRIDAAARDELGQLARDFNLLAQALEHNERARRDF
MADISHELRTPLAVLRAELEALQDGIRPMTPISLGSLHQQVGQLGKLIEDLYDVSLTDVGALAYRRAPVDLAVILATVLD
GLHARFAAAQLQVQAQIDAGPLQLDGDERRLQQLLGNLLENTLRYTDAGGTVQVRCVRRGAVLELVVEDSAPGVDADKRA
RLFERFYRTEASRNRASGGGGLGLAICRNIAEAHGGSIHAEASALGGLRMVLRLPALAA
>Mature_459_residues
MKLGITAKLFLAILAACVAVLLINGIAVQAFVKRQFLDYLNEQGVERMQETLPRVRAEYARHGSWEFVRDNPDAWFVLMR
PERGPGPPREAPPISDQTGAVFRFALLDQDYTPVIGNPDVGRHDILRPVVVGGRTVGWMAMLPFQKALAAADARFYAAQQ
RAWWAIGGACLLVAALLGWLLSRTLLRRLRGLTQATHLLAAGDYATRIDAAARDELGQLARDFNLLAQALEHNERARRDF
MADISHELRTPLAVLRAELEALQDGIRPMTPISLGSLHQQVGQLGKLIEDLYDVSLTDVGALAYRRAPVDLAVILATVLD
GLHARFAAAQLQVQAQIDAGPLQLDGDERRLQQLLGNLLENTLRYTDAGGTVQVRCVRRGAVLELVVEDSAPGVDADKRA
RLFERFYRTEASRNRASGGGGLGLAICRNIAEAHGGSIHAEASALGGLRMVLRLPALAA

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=463, Percent_Identity=45.5723542116631, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1786783, Length=271, Percent_Identity=30.9963099630996, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=30.4347826086957, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1787894, Length=254, Percent_Identity=31.496062992126, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=34.0425531914894, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=29.0196078431373, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1789149, Length=317, Percent_Identity=25.5520504731861, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=30.4166666666667, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=32.0675105485232, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787374, Length=293, Percent_Identity=27.9863481228669, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788279, Length=270, Percent_Identity=25.1851851851852, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789808, Length=289, Percent_Identity=26.2975778546713, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=29.0598290598291, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=274, Percent_Identity=26.2773722627737, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=26.431718061674, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790861, Length=361, Percent_Identity=25.7617728531856, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789403, Length=216, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=209, Percent_Identity=32.5358851674641, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=26.2295081967213, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788549, Length=219, Percent_Identity=24.6575342465753, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50109; Mature: 50109

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGITAKLFLAILAACVAVLLINGIAVQAFVKRQFLDYLNEQGVERMQETLPRVRAEYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHGSWEFVRDNPDAWFVLMRPERGPGPPREAPPISDQTGAVFRFALLDQDYTPVIGNPDV
HCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
GRHDILRPVVVGGRTVGWMAMLPFQKALAAADARFYAAQQRAWWAIGGACLLVAALLGWL
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRTLLRRLRGLTQATHLLAAGDYATRIDAAARDELGQLARDFNLLAQALEHNERARRDF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MADISHELRTPLAVLRAELEALQDGIRPMTPISLGSLHQQVGQLGKLIEDLYDVSLTDVG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALAYRRAPVDLAVILATVLDGLHARFAAAQLQVQAQIDAGPLQLDGDERRLQQLLGNLLE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEECCHHHHHHHHHHHHHH
NTLRYTDAGGTVQVRCVRRGAVLELVVEDSAPGVDADKRARLFERFYRTEASRNRASGGG
HHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
GLGLAICRNIAEAHGGSIHAEASALGGLRMVLRLPALAA
CHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLGITAKLFLAILAACVAVLLINGIAVQAFVKRQFLDYLNEQGVERMQETLPRVRAEYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHGSWEFVRDNPDAWFVLMRPERGPGPPREAPPISDQTGAVFRFALLDQDYTPVIGNPDV
HCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
GRHDILRPVVVGGRTVGWMAMLPFQKALAAADARFYAAQQRAWWAIGGACLLVAALLGWL
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRTLLRRLRGLTQATHLLAAGDYATRIDAAARDELGQLARDFNLLAQALEHNERARRDF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MADISHELRTPLAVLRAELEALQDGIRPMTPISLGSLHQQVGQLGKLIEDLYDVSLTDVG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALAYRRAPVDLAVILATVLDGLHARFAAAQLQVQAQIDAGPLQLDGDERRLQQLLGNLLE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEECCHHHHHHHHHHHHHH
NTLRYTDAGGTVQVRCVRRGAVLELVVEDSAPGVDADKRARLFERFYRTEASRNRASGGG
HHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
GLGLAICRNIAEAHGGSIHAEASALGGLRMVLRLPALAA
CHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]