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The map label for this gene is tldD [C]

Identifier: 78045649

GI number: 78045649

Start: 110149

End: 111777

Strand: Reverse

Name: tldD [C]

Synonym: XCV0093

Alternate gene names: 78045649

Gene position: 111777-110149 (Counterclockwise)

Preceding gene: 78045650

Following gene: 78045648

Centisome position: 2.16

GC content: 64.7

Gene sequence:

>1629_bases
GTGGACCGTCGTACCTTCCTCACCCTGTCCGGCATCGGCGCCGCCGGGCTGCTACTCCCCAACACGCGGCTAATCGCCGC
CGAGCAGCTGCTTGCCCCAGTGGATGCAGCACGCAACCGGCGCCTTTCAGATGCCGCACTCACCACCGCCAAGGCTGCCG
GTGCCAGCTATTGCGACGTGCGCGTGGGGCGTTATCTGCGCCAGTTCGTGATCACCCGCGAGGCGCAGGTGGAAAACGTG
GTCAATGCCGAATCCATCGGGGTGGGCGTGCGCGTGCTGGCCGATGGCGCCTGGGGGTTTGCGGCCACCAACACATTGAC
CAGCGATGGCGTGGCCACCGCCACGCGGCAGGCGTTGGCCATTGCCAAGGCGAATGCGCGCTTGGGCGGCACGCCGGTGC
AGCTGGCGCCGGTGACGCCGGCCGGACAGGTCAGCTGGAAGACGCCGATCAGGAAGAACGCCATGGAAGTGCCGCTGCAG
GACAAGGTGGCGCTGCTGATGGACGTCAATGCAGCTGCGCTCAATGCCGGGGCCACCTTCGTGGCCTCGCGCATGTTTGC
GATCAATGAGCAAAAGTATTTCGCCAGCAGCGATGGCTCCTACATCGATCAGGACGTGCACCGGTTGTGGCTGCCCTTCA
CCGTCACTGCAGTGGACAAGGCCAGCGGCAAGTTCCGCACCCGCGATGGGCTGTCCTCGCCCATGGGCATGGGCTACGAA
TATCTGGATGGCGATGCCGGCCAGAAGCACCAGCTGCCAGGCGGGCTGATCGGTTACGGGCACAGCTACGATGCGCGCGA
AGATGCGATCGCCGCGGCCAGGCAGGCGCGCGCCAAACTCACCGCGCCGTCGGTGAAGGCAGGCAAGTACGATCTGGTGA
TCGACCCGAGCAATCTGTTCCTCACCATCCATGAGTCGGTCGGGCACCCGCTGGAGCTCGATCGCGTGCTGGGTTACGAG
GCCAACTACGCCGGCACCAGTTTCGCCACCCTGGACAAGCGCGATGCAGGTTACCGCTGGGGCAGCGATGCGGTGACCTT
CGTCGCCGACAAGACCCAGCCGGGCAGCCTGGGTGCGGTGGGGTACGACGATGAGGGCGTCAAGACCAAACAATGGGAGC
TGGTGAAGGACGGCATCCTGGTCGACTACCAATGCACGCGCGATCAGGCGCACCTGCTCGGCAAGACTGCGTCCGATGGC
TGTAGCTACGCCGATTCGTGGTCGAACGTGCAATTCCAGCGCATGCCCAATGTGTCGTTGGCGCCAGGCAGGACGCCGTT
GGCGGTTGCCGACATGATCAGGAACGTGGAGCACGGCTTGTACATCCATGGGCGCGGTTCGTATTCGATCGACCAGCAGC
GCTACAACGCGCAGTTCGGCGGGCAGCTGTTCTACGAGATCGAAAACGGCCAGGTCACCCGCTTGGTGGAAGACGGCGCC
TACCAGATCCGCACGCCGGAATTCTGGAATGCCTGTAGCGCCGTGTGCGACCAGCGCGACTTCCGCCTGGGTGGCTCGTT
CTTCGATGGCAAGGGCCAGCCGAGCCAGGTCTCGGCGGTGTCGCATGGCGCGTCCACCGCGCGCTTCGATGGCATCAACG
TGATCAATACCGCGCGTTCGTTGGGTTGA

Upstream 100 bases:

>100_bases
ATCGAACACCGCTAGCACTTGACCAAATCGGTGTACGCGGTAACGCTCGGATGCCGGTGTGCGCCTCTCGCGCTGCACGC
ATCGATTGGAGAGACCGCAC

Downstream 100 bases:

>100_bases
GGGTTGGTGGATCGACTGCGTGGTGATTGAGTTGTCTGCGTTGGCTCAGCACATTTAGGCACTGAGATTGTGTTTGTTGC
GGTCGCTTAACTATCTTCAA

Product: putative modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MDRRTFLTLSGIGAAGLLLPNTRLIAAEQLLAPVDAARNRRLSDAALTTAKAAGASYCDVRVGRYLRQFVITREAQVENV
VNAESIGVGVRVLADGAWGFAATNTLTSDGVATATRQALAIAKANARLGGTPVQLAPVTPAGQVSWKTPIRKNAMEVPLQ
DKVALLMDVNAAALNAGATFVASRMFAINEQKYFASSDGSYIDQDVHRLWLPFTVTAVDKASGKFRTRDGLSSPMGMGYE
YLDGDAGQKHQLPGGLIGYGHSYDAREDAIAAARQARAKLTAPSVKAGKYDLVIDPSNLFLTIHESVGHPLELDRVLGYE
ANYAGTSFATLDKRDAGYRWGSDAVTFVADKTQPGSLGAVGYDDEGVKTKQWELVKDGILVDYQCTRDQAHLLGKTASDG
CSYADSWSNVQFQRMPNVSLAPGRTPLAVADMIRNVEHGLYIHGRGSYSIDQQRYNAQFGGQLFYEIENGQVTRLVEDGA
YQIRTPEFWNACSAVCDQRDFRLGGSFFDGKGQPSQVSAVSHGASTARFDGINVINTARSLG

Sequences:

>Translated_542_residues
MDRRTFLTLSGIGAAGLLLPNTRLIAAEQLLAPVDAARNRRLSDAALTTAKAAGASYCDVRVGRYLRQFVITREAQVENV
VNAESIGVGVRVLADGAWGFAATNTLTSDGVATATRQALAIAKANARLGGTPVQLAPVTPAGQVSWKTPIRKNAMEVPLQ
DKVALLMDVNAAALNAGATFVASRMFAINEQKYFASSDGSYIDQDVHRLWLPFTVTAVDKASGKFRTRDGLSSPMGMGYE
YLDGDAGQKHQLPGGLIGYGHSYDAREDAIAAARQARAKLTAPSVKAGKYDLVIDPSNLFLTIHESVGHPLELDRVLGYE
ANYAGTSFATLDKRDAGYRWGSDAVTFVADKTQPGSLGAVGYDDEGVKTKQWELVKDGILVDYQCTRDQAHLLGKTASDG
CSYADSWSNVQFQRMPNVSLAPGRTPLAVADMIRNVEHGLYIHGRGSYSIDQQRYNAQFGGQLFYEIENGQVTRLVEDGA
YQIRTPEFWNACSAVCDQRDFRLGGSFFDGKGQPSQVSAVSHGASTARFDGINVINTARSLG
>Mature_542_residues
MDRRTFLTLSGIGAAGLLLPNTRLIAAEQLLAPVDAARNRRLSDAALTTAKAAGASYCDVRVGRYLRQFVITREAQVENV
VNAESIGVGVRVLADGAWGFAATNTLTSDGVATATRQALAIAKANARLGGTPVQLAPVTPAGQVSWKTPIRKNAMEVPLQ
DKVALLMDVNAAALNAGATFVASRMFAINEQKYFASSDGSYIDQDVHRLWLPFTVTAVDKASGKFRTRDGLSSPMGMGYE
YLDGDAGQKHQLPGGLIGYGHSYDAREDAIAAARQARAKLTAPSVKAGKYDLVIDPSNLFLTIHESVGHPLELDRVLGYE
ANYAGTSFATLDKRDAGYRWGSDAVTFVADKTQPGSLGAVGYDDEGVKTKQWELVKDGILVDYQCTRDQAHLLGKTASDG
CSYADSWSNVQFQRMPNVSLAPGRTPLAVADMIRNVEHGLYIHGRGSYSIDQQRYNAQFGGQLFYEIENGQVTRLVEDGA
YQIRTPEFWNACSAVCDQRDFRLGGSFFDGKGQPSQVSAVSHGASTARFDGINVINTARSLG

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=278, Percent_Identity=29.8561151079137, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 58323; Mature: 58323

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRRTFLTLSGIGAAGLLLPNTRLIAAEQLLAPVDAARNRRLSDAALTTAKAAGASYCDV
CCCEEEEEEECCCCCEEECCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHH
RVGRYLRQFVITREAQVENVVNAESIGVGVRVLADGAWGFAATNTLTSDGVATATRQALA
HHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCEEECCCCCCCCHHHHHHHHHE
IAKANARLGGTPVQLAPVTPAGQVSWKTPIRKNAMEVPLQDKVALLMDVNAAALNAGATF
EEECCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCEEEEEECCHHHHCCCHHH
VASRMFAINEQKYFASSDGSYIDQDVHRLWLPFTVTAVDKASGKFRTRDGLSSPMGMGYE
HHHHHHEECCCCEEECCCCCHHHHHHHHEECCEEEEEEECCCCCEECCCCCCCCCCCCCC
YLDGDAGQKHQLPGGLIGYGHSYDAREDAIAAARQARAKLTAPSVKAGKYDLVIDPSNLF
EECCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEE
LTIHESVGHPLELDRVLGYEANYAGTSFATLDKRDAGYRWGSDAVTFVADKTQPGSLGAV
EEEEHHCCCCEEHHHHHCCCCCCCCCEEEEECCCCCCCEECCCCEEEEECCCCCCCCEEC
GYDDEGVKTKQWELVKDGILVDYQCTRDQAHLLGKTASDGCSYADSWSNVQFQRMPNVSL
CCCCCCCCCHHEEEECCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCC
APGRTPLAVADMIRNVEHGLYIHGRGSYSIDQQRYNAQFGGQLFYEIENGQVTRLVEDGA
CCCCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHCCCCCCEEEEEECCCEEEEEEECCC
YQIRTPEFWNACSAVCDQRDFRLGGSFFDGKGQPSQVSAVSHGASTARFDGINVINTARS
EEEECCHHHHHHHHHHCCCCCEECCCEECCCCCCCHHHHHHCCCCCEEECCCCHHHHHHH
LG
CC
>Mature Secondary Structure
MDRRTFLTLSGIGAAGLLLPNTRLIAAEQLLAPVDAARNRRLSDAALTTAKAAGASYCDV
CCCEEEEEEECCCCCEEECCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHH
RVGRYLRQFVITREAQVENVVNAESIGVGVRVLADGAWGFAATNTLTSDGVATATRQALA
HHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCEEECCCCCCCCHHHHHHHHHE
IAKANARLGGTPVQLAPVTPAGQVSWKTPIRKNAMEVPLQDKVALLMDVNAAALNAGATF
EEECCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCEEEEEECCHHHHCCCHHH
VASRMFAINEQKYFASSDGSYIDQDVHRLWLPFTVTAVDKASGKFRTRDGLSSPMGMGYE
HHHHHHEECCCCEEECCCCCHHHHHHHHEECCEEEEEEECCCCCEECCCCCCCCCCCCCC
YLDGDAGQKHQLPGGLIGYGHSYDAREDAIAAARQARAKLTAPSVKAGKYDLVIDPSNLF
EECCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEE
LTIHESVGHPLELDRVLGYEANYAGTSFATLDKRDAGYRWGSDAVTFVADKTQPGSLGAV
EEEEHHCCCCEEHHHHHCCCCCCCCCEEEEECCCCCCCEECCCCEEEEECCCCCCCCEEC
GYDDEGVKTKQWELVKDGILVDYQCTRDQAHLLGKTASDGCSYADSWSNVQFQRMPNVSL
CCCCCCCCCHHEEEECCCEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCC
APGRTPLAVADMIRNVEHGLYIHGRGSYSIDQQRYNAQFGGQLFYEIENGQVTRLVEDGA
CCCCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHCCCCCCEEEEEECCCEEEEEEECCC
YQIRTPEFWNACSAVCDQRDFRLGGSFFDGKGQPSQVSAVSHGASTARFDGINVINTARS
EEEECCHHHHHHHHHHCCCCCEECCCEECCCCCCCHHHHHHCCCCCEEECCCCHHHHHHH
LG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]