Click here to switch to the map view.

The map label for this gene is era

Identifier: 78045135

GI number: 78045135

Start: 371033

End: 371929

Strand: Direct

Name: era

Synonym: CHY_0430

Alternate gene names: 78045135

Gene position: 371033-371929 (Clockwise)

Preceding gene: 78044559

Following gene: 78044577

Centisome position: 15.45

GC content: 42.36

Gene sequence:

>897_bases
ATGAGTTATAAATCGGGCTTTGTTTCCATCGTTGGCCGACCCAATGTTGGAAAATCCACTCTTTTAAACCAAGTGGTGGG
GACGAAAATTGCAATAATGTCCGATAAACCCCAGACTACCCGGAATAAAATCCGGGCAGTATTGACTTCGGAAAAAGGCC
AGATTATTTTTATCGATACTCCCGGCGTACAAAAACCCAGAAATAAACTTGGGGAGTTTATGTTAAAGCAGGCTTTAACC
AGTTTGGACGAAGTAGATGTTCTTTTATACGTGGTCGAAGCCAATTCACCGATAGGTCCGCAGGAAAATTATCTCTTAAA
GACTTTAGCTGAAGTAAAAACTCCGATAATCTTAGTGGTAAATAAAATTGATGTGGTAAAGATGATTGAGGCCCAAACTC
TTGCCAGGCAAATTGAAAGCAGATTAAAGGTTGCCAAAACTTATTACATATCGGCCTTAAACGGAACGGGAGTTTCGGAA
CTGGTGGAGGGAATTTTTGAATTATTACCCGAGGGGCCGCCGTATTATCCGGAAGGGCAGGTTACCGATTATCCGGAACG
ATTTATCATTGCGGAGTACATTCGGGAGCAAATACTGCATTTGACCCGGGAAGAAATTCCGCACTCGGTGGCAGTCGTGG
TGGAGGAAATAAAACCCCGGGAAAACAGCAATACCGTTTATGTTTCCGCAGTAATTTACGTGGAAAGGGAGAGTCAAAAA
GGAATCATCATTGGCAAAAATGGGCAAATGTTAAAAGAGATTGGGCAAAGGGCTCGACTGGAAATTGAGCGGCTACTGGG
TAGTAATATTTACCTTGATTTATGGGTAAAGGTAAAGGAAGACTGGCGGAACAAAGATGTCTGGATTCGCAATTTTGGTT
TTACGGAGTTTGAATAA

Upstream 100 bases:

>100_bases
CCTGAAAAGGATATAATACCCTTAAATCTTTCGGTAGAAGATGCGCTAAAAATTATTGTATCCGGTGGGATAGTCCAACC
AGAAAGGGGGGAAGAAAAAG

Downstream 100 bases:

>100_bases
CCCTTTGCAATAGAGCGGGCTTAGGCCCGCTTTATTTGTGCCGGTGAGGTGTGATACTATAAAAATTTTTTATAGTGGGC
CTGTTATAAAACAAAAACGT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSYKSGFVSIVGRPNVGKSTLLNQVVGTKIAIMSDKPQTTRNKIRAVLTSEKGQIIFIDTPGVQKPRNKLGEFMLKQALT
SLDEVDVLLYVVEANSPIGPQENYLLKTLAEVKTPIILVVNKIDVVKMIEAQTLARQIESRLKVAKTYYISALNGTGVSE
LVEGIFELLPEGPPYYPEGQVTDYPERFIIAEYIREQILHLTREEIPHSVAVVVEEIKPRENSNTVYVSAVIYVERESQK
GIIIGKNGQMLKEIGQRARLEIERLLGSNIYLDLWVKVKEDWRNKDVWIRNFGFTEFE

Sequences:

>Translated_298_residues
MSYKSGFVSIVGRPNVGKSTLLNQVVGTKIAIMSDKPQTTRNKIRAVLTSEKGQIIFIDTPGVQKPRNKLGEFMLKQALT
SLDEVDVLLYVVEANSPIGPQENYLLKTLAEVKTPIILVVNKIDVVKMIEAQTLARQIESRLKVAKTYYISALNGTGVSE
LVEGIFELLPEGPPYYPEGQVTDYPERFIIAEYIREQILHLTREEIPHSVAVVVEEIKPRENSNTVYVSAVIYVERESQK
GIIIGKNGQMLKEIGQRARLEIERLLGSNIYLDLWVKVKEDWRNKDVWIRNFGFTEFE
>Mature_297_residues
SYKSGFVSIVGRPNVGKSTLLNQVVGTKIAIMSDKPQTTRNKIRAVLTSEKGQIIFIDTPGVQKPRNKLGEFMLKQALTS
LDEVDVLLYVVEANSPIGPQENYLLKTLAEVKTPIILVVNKIDVVKMIEAQTLARQIESRLKVAKTYYISALNGTGVSEL
VEGIFELLPEGPPYYPEGQVTDYPERFIIAEYIREQILHLTREEIPHSVAVVVEEIKPRENSNTVYVSAVIYVERESQKG
IIIGKNGQMLKEIGQRARLEIERLLGSNIYLDLWVKVKEDWRNKDVWIRNFGFTEFE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Homo sapiens, GI24307899, Length=326, Percent_Identity=25.1533742331288, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1788919, Length=296, Percent_Identity=36.4864864864865, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI87082120, Length=167, Percent_Identity=32.9341317365269, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI2367268, Length=124, Percent_Identity=30.6451612903226, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=139, Percent_Identity=31.6546762589928, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646434, Length=310, Percent_Identity=25.1612903225806, Blast_Score=88, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_CARHZ (Q3AEZ3)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359291.1
- ProteinModelPortal:   Q3AEZ3
- SMR:   Q3AEZ3
- STRING:   Q3AEZ3
- GeneID:   3728261
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0430
- NMPDR:   fig|246194.3.peg.763
- TIGR:   CHY_0430
- eggNOG:   COG1159
- HOGENOM:   HBG561652
- OMA:   QNATRRK
- BioCyc:   CHYD246194:CHY_0430-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PRINTS:   PR00326
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 33794; Mature: 33662

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKSGFVSIVGRPNVGKSTLLNQVVGTKIAIMSDKPQTTRNKIRAVLTSEKGQIIFIDT
CCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHEECCCCCEEEEEC
PGVQKPRNKLGEFMLKQALTSLDEVDVLLYVVEANSPIGPQENYLLKTLAEVKTPIILVV
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEE
NKIDVVKMIEAQTLARQIESRLKVAKTYYISALNGTGVSELVEGIFELLPEGPPYYPEGQ
ECCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCC
VTDYPERFIIAEYIREQILHLTREEIPHSVAVVVEEIKPRENSNTVYVSAVIYVERESQK
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCC
GIIIGKNGQMLKEIGQRARLEIERLLGSNIYLDLWVKVKEDWRNKDVWIRNFGFTEFE
CEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SYKSGFVSIVGRPNVGKSTLLNQVVGTKIAIMSDKPQTTRNKIRAVLTSEKGQIIFIDT
CCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHEECCCCCEEEEEC
PGVQKPRNKLGEFMLKQALTSLDEVDVLLYVVEANSPIGPQENYLLKTLAEVKTPIILVV
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEE
NKIDVVKMIEAQTLARQIESRLKVAKTYYISALNGTGVSELVEGIFELLPEGPPYYPEGQ
ECCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCC
VTDYPERFIIAEYIREQILHLTREEIPHSVAVVVEEIKPRENSNTVYVSAVIYVERESQK
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCC
GIIIGKNGQMLKEIGQRARLEIERLLGSNIYLDLWVKVKEDWRNKDVWIRNFGFTEFE
CEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA