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The map label for this gene is yeiI [H]

Identifier: 78045094

GI number: 78045094

Start: 66711

End: 67805

Strand: Direct

Name: yeiI [H]

Synonym: CHY_0076

Alternate gene names: 78045094

Gene position: 66711-67805 (Clockwise)

Preceding gene: 78043610

Following gene: 78044666

Centisome position: 2.78

GC content: 42.83

Gene sequence:

>1095_bases
ATGACCCGGCGGGAGGAAGAAATCTTAAAATTAATTCGGGAAAATCCTTTTATCAATCAAGAAGAAATAGCCCGGATCCT
CGGGATTACCCGGTCCAGCGTGGGAGTGCATATCGTTAATTTGATGAAAAAAGGTAAAATTAAAGGACGGGGTTACATTC
TTTCTGCCGATGAGCCGGAAGTTACCGTTGTCGGTGGGGCCAATATTGATATTTATGGCTTTCCTTATGAAAAGCTTCGC
CTGCAGGATTCAAATCCGGGGAAAGTAAAAATGAACGTGGGCGGGGTTGCCAGGAATATAGCGGAAAATCTGGCTCGGCT
GGGGGTAGCTACAAGACTTATTACCGCTATAGGAGATGATTTTTACGGGAAATACATTATCGAGCGCTGCCGGGACGCAG
GTGTGAACATGGAAGAAATTTTAACCGTAAGTGGTGAAAGCTCTTCGGTTTATCTTGCCGTAATGGATGAAGCCGGGGAT
ATGGCGGTGGCTGTAGCGGGGATGGATATTTTAAACCATTTAAGTTTAGATTTTCTAAAAAAGAAACTTTCAATAATAAA
TTCATCTCCCGTTTGCGTGGTAGATACCAATCTTCCGGTAAAAAGTTTAGAGTTTCTCTTAGATAATGCGCGAAAAACAG
TATTTTTCTTGGATGGGGTATCGGTGACCAAAGCTCTTAAATTAAAAGAACTTCGAGGAACATTTTATGCGGTAAAATTA
AATAAATTGGAAGCGGAAGGGGTAACCGGAGAAAACTTAAATACCGAGGCGGGGCTTTTAAAAGCGGCAAACTTTTTCCT
GGATAAAGGAATCAAACAGGTTTATTTTACCCTTGGGGCCCAAGGGGTTTTTTACGCTAACACCAAGAGCCGGGGAAAAA
TAACATTACCACCGGTACAGCCGGTTAATACTACCGGAGCTGGCGATGCCTTTACGGCAGCGATTGTTTACAGTTATTTA
AAGGGATATGATATAGATAGGGCTGCCCGCTTTGGGGCGGCTGCGGCAATTTTAACTCTTCTGGTGGAAGAAACGGTTAA
TCCTGAAATATCCGAAGAAAAAATTAAAAAGGAAATGGAGGTGTTGGGACTATGA

Upstream 100 bases:

>100_bases
ATTAAGGAACAATTAAAAAACTATTTCACATTAGAATTTTTTTTTGGTTATAATTATAAATAGATGCTTAGATATAATAA
GCAAAAGCTTAGGAGGAGTT

Downstream 100 bases:

>100_bases
ATGAATATTTGGTTTTAAGTAAGGAAGTAAAAGAGGCTTTGGCTGAAGGTGTGCCGGTAGTAGCCTTGGAATCAACCATT
ATTGCTCATGGTATGCCGCA

Product: PfkB family kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MTRREEEILKLIRENPFINQEEIARILGITRSSVGVHIVNLMKKGKIKGRGYILSADEPEVTVVGGANIDIYGFPYEKLR
LQDSNPGKVKMNVGGVARNIAENLARLGVATRLITAIGDDFYGKYIIERCRDAGVNMEEILTVSGESSSVYLAVMDEAGD
MAVAVAGMDILNHLSLDFLKKKLSIINSSPVCVVDTNLPVKSLEFLLDNARKTVFFLDGVSVTKALKLKELRGTFYAVKL
NKLEAEGVTGENLNTEAGLLKAANFFLDKGIKQVYFTLGAQGVFYANTKSRGKITLPPVQPVNTTGAGDAFTAAIVYSYL
KGYDIDRAARFGAAAAILTLLVEETVNPEISEEKIKKEMEVLGL

Sequences:

>Translated_364_residues
MTRREEEILKLIRENPFINQEEIARILGITRSSVGVHIVNLMKKGKIKGRGYILSADEPEVTVVGGANIDIYGFPYEKLR
LQDSNPGKVKMNVGGVARNIAENLARLGVATRLITAIGDDFYGKYIIERCRDAGVNMEEILTVSGESSSVYLAVMDEAGD
MAVAVAGMDILNHLSLDFLKKKLSIINSSPVCVVDTNLPVKSLEFLLDNARKTVFFLDGVSVTKALKLKELRGTFYAVKL
NKLEAEGVTGENLNTEAGLLKAANFFLDKGIKQVYFTLGAQGVFYANTKSRGKITLPPVQPVNTTGAGDAFTAAIVYSYL
KGYDIDRAARFGAAAAILTLLVEETVNPEISEEKIKKEMEVLGL
>Mature_363_residues
TRREEEILKLIRENPFINQEEIARILGITRSSVGVHIVNLMKKGKIKGRGYILSADEPEVTVVGGANIDIYGFPYEKLRL
QDSNPGKVKMNVGGVARNIAENLARLGVATRLITAIGDDFYGKYIIERCRDAGVNMEEILTVSGESSSVYLAVMDEAGDM
AVAVAGMDILNHLSLDFLKKKLSIINSSPVCVVDTNLPVKSLEFLLDNARKTVFFLDGVSVTKALKLKELRGTFYAVKLN
KLEAEGVTGENLNTEAGLLKAANFFLDKGIKQVYFTLGAQGVFYANTKSRGKITLPPVQPVNTTGAGDAFTAAIVYSYLK
GYDIDRAARFGAAAAILTLLVEETVNPEISEEKIKKEMEVLGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=247, Percent_Identity=30.3643724696356, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788484, Length=355, Percent_Identity=36.056338028169, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1788491, Length=292, Percent_Identity=35.2739726027397, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI87081971, Length=307, Percent_Identity=28.0130293159609, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790193, Length=232, Percent_Identity=25.4310344827586, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25147470, Length=307, Percent_Identity=25.4071661237785, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580669, Length=297, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: NA

Molecular weight: Translated: 39691; Mature: 39559

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRREEEILKLIRENPFINQEEIARILGITRSSVGVHIVNLMKKGKIKGRGYILSADEPE
CCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCC
VTVVGGANIDIYGFPYEKLRLQDSNPGKVKMNVGGVARNIAENLARLGVATRLITAIGDD
EEEEECCEEEEEECCHHHEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCH
FYGKYIIERCRDAGVNMEEILTVSGESSSVYLAVMDEAGDMAVAVAGMDILNHLSLDFLK
HHHHHHHHHHHHCCCCHHHEEEECCCCCEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHH
KKLSIINSSPVCVVDTNLPVKSLEFLLDNARKTVFFLDGVSVTKALKLKELRGTFYAVKL
HHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCEEEEEEE
NKLEAEGVTGENLNTEAGLLKAANFFLDKGIKQVYFTLGAQGVFYANTKSRGKITLPPVQ
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCC
PVNTTGAGDAFTAAIVYSYLKGYDIDRAARFGAAAAILTLLVEETVNPEISEEKIKKEME
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VLGL
HHCC
>Mature Secondary Structure 
TRREEEILKLIRENPFINQEEIARILGITRSSVGVHIVNLMKKGKIKGRGYILSADEPE
CCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCC
VTVVGGANIDIYGFPYEKLRLQDSNPGKVKMNVGGVARNIAENLARLGVATRLITAIGDD
EEEEECCEEEEEECCHHHEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCH
FYGKYIIERCRDAGVNMEEILTVSGESSSVYLAVMDEAGDMAVAVAGMDILNHLSLDFLK
HHHHHHHHHHHHCCCCHHHEEEECCCCCEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHH
KKLSIINSSPVCVVDTNLPVKSLEFLLDNARKTVFFLDGVSVTKALKLKELRGTFYAVKL
HHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCEEEEEEE
NKLEAEGVTGENLNTEAGLLKAANFFLDKGIKQVYFTLGAQGVFYANTKSRGKITLPPVQ
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCC
PVNTTGAGDAFTAAIVYSYLKGYDIDRAARFGAAAAILTLLVEETVNPEISEEKIKKEME
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VLGL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 2460435 [H]