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The map label for this gene is huP [H]

Identifier: 78045062

GI number: 78045062

Start: 172677

End: 172946

Strand: Direct

Name: huP [H]

Synonym: CHY_0205

Alternate gene names: 78045062

Gene position: 172677-172946 (Clockwise)

Preceding gene: 78044244

Following gene: 78042798

Centisome position: 7.19

GC content: 40.0

Gene sequence:

>270_bases
GTGAACAAAGCTGAATTAGTAAGTGTAATTGCTGAAAAGGCCGAAATGACTAAAAAGGATGCGGAAAAAGCCTTAAATGC
GGTTTTAGCAGCAATTGAAGAAGCTTTGAAAAAAGGTGAAAAAGTACAGTTGGTCGGTTTTGGTACTTTTGAAGTAAGAG
AAAGAGCCGCACGGAAGGGTAGAAACCCGCAAACCGGTCAGGAAATCGAAATTCCCGCTTCCAAAGTTCCGGTATTTAAG
CCCGGCAAGCTTTTAAAAGAAAAAATTTAA

Upstream 100 bases:

>100_bases
AGATTTTTTTTGATAGTTTGCAGGAAAATGAAGGATTGTAGCGAATTAAGTAAAACGATAATTTAAGTACATAAAAAATT
TTTTCAAGGAGGGAATATAA

Downstream 100 bases:

>100_bases
TAAAAAAGCCAGGTGCCTAAAGCATCTGGCTTTTTTCTGTGTTTGCATAACCCTTCCTCTTTTTGGACAAAATAACCAAA
AATTGAGGAGGGGTTTTATG

Product: DNA-binding protein HU

Products: NA

Alternate protein names: DNA-binding protein II; HB [H]

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MNKAELVSVIAEKAEMTKKDAEKALNAVLAAIEEALKKGEKVQLVGFGTFEVRERAARKGRNPQTGQEIEIPASKVPVFK
PGKLLKEKI

Sequences:

>Translated_89_residues
MNKAELVSVIAEKAEMTKKDAEKALNAVLAAIEEALKKGEKVQLVGFGTFEVRERAARKGRNPQTGQEIEIPASKVPVFK
PGKLLKEKI
>Mature_89_residues
MNKAELVSVIAEKAEMTKKDAEKALNAVLAAIEEALKKGEKVQLVGFGTFEVRERAARKGRNPQTGQEIEIPASKVPVFK
PGKLLKEKI

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=60.6741573033708, Blast_Score=111, Evalue=8e-27,
Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=56.1797752808989, Blast_Score=108, Evalue=5e-26,
Organism=Escherichia coli, GI1788005, Length=89, Percent_Identity=39.3258426966292, Blast_Score=78, Evalue=9e-17,
Organism=Escherichia coli, GI1787141, Length=89, Percent_Identity=38.2022471910112, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9745; Mature: 9745

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAELVSVIAEKAEMTKKDAEKALNAVLAAIEEALKKGEKVQLVGFGTFEVRERAARKG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCC
RNPQTGQEIEIPASKVPVFKPGKLLKEKI
CCCCCCCEEECCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MNKAELVSVIAEKAEMTKKDAEKALNAVLAAIEEALKKGEKVQLVGFGTFEVRERAARKG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCC
RNPQTGQEIEIPASKVPVFKPGKLLKEKI
CCCCCCCEEECCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644313 [H]