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The map label for this gene is ycbL [H]

Identifier: 78045027

GI number: 78045027

Start: 525167

End: 525847

Strand: Direct

Name: ycbL [H]

Synonym: CHY_0606

Alternate gene names: 78045027

Gene position: 525167-525847 (Clockwise)

Preceding gene: 78043110

Following gene: 78044270

Centisome position: 21.87

GC content: 41.85

Gene sequence:

>681_bases
ATGTATAAAATTTTAGTGGTGGAAGATGACCAGAAAATCCAAAAAGCTCTTGCCCATCTTTTAAAGGCTGAAAATTACGA
TTTTGTGCAGGCGTACGATGGAGAGGCGGCAGTAGAACATTTTTACCGGGAAAATTTTGACCTTGTTATATTAGATTTAA
ACCTTCCGAAACAGGACGGATTTTCGGTATTAAAGGAAATTAAAAACCGGGAAGACGTTCCGGTAATTATCCTAACTGCC
CGAGGGGAGGAGATGGATAAGATTACCGGATTTACCCTTGGAGTAGATGATTACTTAACCAAACCCTTTAGTCCTGCGGA
ATTAATGCTTAGAATAAAGGCAGTCTTGCGTCGTTACCGCAAAGGCAGGGGTGAGGAGGAGATCCTGAAATATGGTAAGG
TAGCTGTGAACTTAAAAACCCGGGAGGTCTTAAAAAACGGGGAGCCGGTGGAGTTGACTTCTAAAGAATATGCTTTACTG
GAACTCCTTTTTAAAAACCCCAACCGGATATTTACTAAAGAACAGATAATGGATAGGCTTTGGCCGGATACTTTTCCCGA
GGATCCCAATATCGTTTCGGTATTGGTTCGAAGACTCCGGGAAAAAATAGAAGAAGACCCCAGTTCCCCGCGGATTATTA
AAACGGTCTGGGGAGTTGGTTATAAAGCAGAAAAAATATAG

Upstream 100 bases:

>100_bases
GCAAAAGACCTGTGTGAACTGCTCGGTTACGAAATTAAAGTAAAGTCGAAACTCGGTCGTGGAAGCAGTTTTTATATTGT
TATTAAGGAAGGGTTTAGCG

Downstream 100 bases:

>100_bases
AAAGGAGCAGGAAAAATGGATTTAAAATTGTCTCACGTTACTTTATTTGTACGGGACCAGGAAGAAGCTTTAGCCTGGTA
TACGGAAAAACTTGGATTTG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MYKILVVEDDQKIQKALAHLLKAENYDFVQAYDGEAAVEHFYRENFDLVILDLNLPKQDGFSVLKEIKNREDVPVIILTA
RGEEMDKITGFTLGVDDYLTKPFSPAELMLRIKAVLRRYRKGRGEEEILKYGKVAVNLKTREVLKNGEPVELTSKEYALL
ELLFKNPNRIFTKEQIMDRLWPDTFPEDPNIVSVLVRRLREKIEEDPSSPRIIKTVWGVGYKAEKI

Sequences:

>Translated_226_residues
MYKILVVEDDQKIQKALAHLLKAENYDFVQAYDGEAAVEHFYRENFDLVILDLNLPKQDGFSVLKEIKNREDVPVIILTA
RGEEMDKITGFTLGVDDYLTKPFSPAELMLRIKAVLRRYRKGRGEEEILKYGKVAVNLKTREVLKNGEPVELTSKEYALL
ELLFKNPNRIFTKEQIMDRLWPDTFPEDPNIVSVLVRRLREKIEEDPSSPRIIKTVWGVGYKAEKI
>Mature_226_residues
MYKILVVEDDQKIQKALAHLLKAENYDFVQAYDGEAAVEHFYRENFDLVILDLNLPKQDGFSVLKEIKNREDVPVIILTA
RGEEMDKITGFTLGVDDYLTKPFSPAELMLRIKAVLRRYRKGRGEEEILKYGKVAVNLKTREVLKNGEPVELTSKEYALL
ELLFKNPNRIFTKEQIMDRLWPDTFPEDPNIVSVLVRRLREKIEEDPSSPRIIKTVWGVGYKAEKI

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=38.4955752212389, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=34.2342342342342, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=35.8744394618834, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=31.0810810810811, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.0807174887892, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=33.6363636363636, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=30.9734513274336, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=36.3636363636364, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=30.9090909090909, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=30.3964757709251, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=35.9090909090909, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=32.8828828828829, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=32.5991189427313, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=27.7056277056277, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=30.1724137931034, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=36.6336633663366, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1788905, Length=100, Percent_Identity=40, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26256; Mature: 26256

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKILVVEDDQKIQKALAHLLKAENYDFVQAYDGEAAVEHFYRENFDLVILDLNLPKQDG
CEEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCH
FSVLKEIKNREDVPVIILTARGEEMDKITGFTLGVDDYLTKPFSPAELMLRIKAVLRRYR
HHHHHHHCCCCCCCEEEEEECCCCHHHHCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHH
KGRGEEEILKYGKVAVNLKTREVLKNGEPVELTSKEYALLELLFKNPNRIFTKEQIMDRL
HCCCHHHHHHHCHHEEEEHHHHHHCCCCCEEECCHHHHHHHHHHCCCCCCCCHHHHHHHH
WPDTFPEDPNIVSVLVRRLREKIEEDPSSPRIIKTVWGVGYKAEKI
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEECCCC
>Mature Secondary Structure
MYKILVVEDDQKIQKALAHLLKAENYDFVQAYDGEAAVEHFYRENFDLVILDLNLPKQDG
CEEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCH
FSVLKEIKNREDVPVIILTARGEEMDKITGFTLGVDDYLTKPFSPAELMLRIKAVLRRYR
HHHHHHHCCCCCCCEEEEEECCCCHHHHCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHH
KGRGEEEILKYGKVAVNLKTREVLKNGEPVELTSKEYALLELLFKNPNRIFTKEQIMDRL
HCCCHHHHHHHCHHEEEEHHHHHHCCCCCEEECCHHHHHHHHHHCCCCCCCCHHHHHHHH
WPDTFPEDPNIVSVLVRRLREKIEEDPSSPRIIKTVWGVGYKAEKI
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]