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The map label for this gene is codB [H]

Identifier: 78045013

GI number: 78045013

Start: 1194060

End: 1195385

Strand: Direct

Name: codB [H]

Synonym: CHY_1335

Alternate gene names: 78045013

Gene position: 1194060-1195385 (Clockwise)

Preceding gene: 78043647

Following gene: 78044454

Centisome position: 49.72

GC content: 38.69

Gene sequence:

>1326_bases
ATGGTAAAAGGTGAAGATTATGCCTTAGCAAGAATTCCCATGGAAGAACGGCGGCCGATGTGGGAAGTTTTCATGATTCG
GTTTGGTGCTGTTGTTACTTTATCGCAGTTTATGCTGGGAGCAGCGCTTGGATATGGTTTGACCCTAAAAGATGCGTTAT
TTGCTACGATCCTTGGGTCGGTGCTACTTGAAATTATTAGCTTTTTAAATGGGGTTGCTGGAGCGTGGGAAGGTCTTTCA
ACCTCTCTTTTAACCCGGTGGGCCGGTTTTGGGAGGTTAGGATCAAGTTTAATTGGATTAATTGTGGGGATTTCATGTAT
TGGTTGGTTTGGAATTCAAAATACGATCTTTGCTCAGGGATTAAGTCAAGCGTTTGGTGGGGCAGTAAGTACCAAGATTA
TGTCGGTAATTACCGGAATATTAATTACCCTGTTAGTTGTATACGGTTATAAAATGTTAAGCTATACAGCTAACATTGCG
GTTCCAGGTTTTTTAGTGGCAGTGGGTATTGCTACCTATCATTTATTAAGCAAATATGACCTTAACACGCTGCTAACTTC
GCCACCCCCTGGTCCAGCTTTGAATTTCGGTGTTGCAGTTACTATGGTTGCCGGGGGCTTTATGGTGGGCGCAGTGGTTA
CTCCTGACCTATCAAGATACAACCGCAACGCCAAAGATGTTTTTTGGATGACGCTTCTTAGTATTTTTGCCGGAGAACTT
TTAATAACTTTTATAGCTGTGTTAATGTCCCATGCGGTAAAAAGTGCTGATGTGATAACTATTATGTTAAATTTAGGTGG
CTGGATTTCAGCTGCTTTAGTAATATTTTCCACGATTAAGATTAATGATTTGAACTTATATGCTGCATCGTTAGGAATTG
CTAATTTCCTTGATGCTGTTTTTAGAGTGAAAATAAGTAGAGCAGTTTTAACGATTATTATAGGCTTATTAGGAACTTTG
GGTTCTGTCTTGGGAATACTGGATAAATTTGTTAACTTTTTAGTTATCCTTGGTATTGCAGTTCCGCCGGTAGGTGGGAT
TATGGTGGTTGATTACTTTATTTTAAAAAGATATAGAAAAGAGCTGGAAGAAAGCCGTGCGTATGGGCGTTTGCCCAGAG
AAGTTGAAGATTGGAATCCCATTGCTATTGTTAGTTTAGTTTTAGCTTTTCTAGTGGGTTATTTTTACAAAGGAGGCTTA
AATCAAGCATTAAATTCATTAATTGCCGGAATGATTTTCTACTTTGTTTTAATGAAATTATATATAGCTTTCTCACCCGC
CAAAAATGCAAAATTTATTAAAAAATCAGAGGTTGGGGAGGTATAA

Upstream 100 bases:

>100_bases
ATTTATAACCTGAAAGACCGGTAAAATTGTTGGCATAAAACTTGCTAAAAAATTAAACCAGTAATATTTAAAAAATAAAT
CTACAAGGGAGGATGGCAAG

Downstream 100 bases:

>100_bases
TTTATGACCAAAATCGATGTACAAATGGTTGAGGACATTGCAGTAGGTGCAGCTCTTCTTGGAACCGGAGGAGGGGGAGA
CCCTTATGTTGGCAAGCTTA

Product: cytosine/purines/uracil/thiamine/allantoin family permease

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MVKGEDYALARIPMEERRPMWEVFMIRFGAVVTLSQFMLGAALGYGLTLKDALFATILGSVLLEIISFLNGVAGAWEGLS
TSLLTRWAGFGRLGSSLIGLIVGISCIGWFGIQNTIFAQGLSQAFGGAVSTKIMSVITGILITLLVVYGYKMLSYTANIA
VPGFLVAVGIATYHLLSKYDLNTLLTSPPPGPALNFGVAVTMVAGGFMVGAVVTPDLSRYNRNAKDVFWMTLLSIFAGEL
LITFIAVLMSHAVKSADVITIMLNLGGWISAALVIFSTIKINDLNLYAASLGIANFLDAVFRVKISRAVLTIIIGLLGTL
GSVLGILDKFVNFLVILGIAVPPVGGIMVVDYFILKRYRKELEESRAYGRLPREVEDWNPIAIVSLVLAFLVGYFYKGGL
NQALNSLIAGMIFYFVLMKLYIAFSPAKNAKFIKKSEVGEV

Sequences:

>Translated_441_residues
MVKGEDYALARIPMEERRPMWEVFMIRFGAVVTLSQFMLGAALGYGLTLKDALFATILGSVLLEIISFLNGVAGAWEGLS
TSLLTRWAGFGRLGSSLIGLIVGISCIGWFGIQNTIFAQGLSQAFGGAVSTKIMSVITGILITLLVVYGYKMLSYTANIA
VPGFLVAVGIATYHLLSKYDLNTLLTSPPPGPALNFGVAVTMVAGGFMVGAVVTPDLSRYNRNAKDVFWMTLLSIFAGEL
LITFIAVLMSHAVKSADVITIMLNLGGWISAALVIFSTIKINDLNLYAASLGIANFLDAVFRVKISRAVLTIIIGLLGTL
GSVLGILDKFVNFLVILGIAVPPVGGIMVVDYFILKRYRKELEESRAYGRLPREVEDWNPIAIVSLVLAFLVGYFYKGGL
NQALNSLIAGMIFYFVLMKLYIAFSPAKNAKFIKKSEVGEV
>Mature_441_residues
MVKGEDYALARIPMEERRPMWEVFMIRFGAVVTLSQFMLGAALGYGLTLKDALFATILGSVLLEIISFLNGVAGAWEGLS
TSLLTRWAGFGRLGSSLIGLIVGISCIGWFGIQNTIFAQGLSQAFGGAVSTKIMSVITGILITLLVVYGYKMLSYTANIA
VPGFLVAVGIATYHLLSKYDLNTLLTSPPPGPALNFGVAVTMVAGGFMVGAVVTPDLSRYNRNAKDVFWMTLLSIFAGEL
LITFIAVLMSHAVKSADVITIMLNLGGWISAALVIFSTIKINDLNLYAASLGIANFLDAVFRVKISRAVLTIIIGLLGTL
GSVLGILDKFVNFLVILGIAVPPVGGIMVVDYFILKRYRKELEESRAYGRLPREVEDWNPIAIVSLVLAFLVGYFYKGGL
NQALNSLIAGMIFYFVLMKLYIAFSPAKNAKFIKKSEVGEV

Specific function: Required for cytosine transport into the cell [H]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI1786530, Length=418, Percent_Identity=27.9904306220096, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 47638; Mature: 47638

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCHHHHHCCCCC
>Mature Secondary Structure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HHHHCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]