Click here to switch to the map view.

The map label for this gene is csd [H]

Identifier: 78044965

GI number: 78044965

Start: 8127

End: 9278

Strand: Direct

Name: csd [H]

Synonym: CHY_0011

Alternate gene names: 78044965

Gene position: 8127-9278 (Clockwise)

Preceding gene: 78043063

Following gene: 78043356

Centisome position: 0.34

GC content: 48.35

Gene sequence:

>1152_bases
GTGCCCACGATTTACTTTGACAACAGTGCCACAACCTACCCCAAACCCCCGGAAGTACTGGAAGCAATGATTTATTTTGC
CGAAAAAGTAGGGGCAAATCCCGGAAGAGGAAGTCACCAAAGGGCTTTAAAAGCCTCCCAAATAATCCTCGAAGCCCGCG
AAGCGGTAAAAAAACTAATCAATGGAGTTTCGGCGGACCGGGTAATTTTTACCGCCAATGCCACGGAAAGCTTAAACTTG
GCCTTAAAAGGCCTTCTTCAAGCGGGAGATCATGTCATAGCGTCGCCCTTTGAGCATAATGCGGTTCAGCGTCCTTTAAA
CCGCTTACGCCGGGAAGGAGTTGAGGTGAGTTACTTATCATCGTCACCTGCGGGAGAAATCGACCCGGACGAAATAAAAA
AGCTTTTAAAGCCCAATACCCGGGCTGTGGTCGTAACCCATGCGTCAAATGTTTTGGGGTGCATCACACCGGTGGCGGAA
GTGGGAAAGATCTGCAGGGAAGCGGGAGTTGCATTAATTGTGGATGCGGCGCAATCCCTGGGAACGATTCCGGTGGATGT
CCAGAGCTATAACATTTCCCTGCTGGCTTTTACCGGTCATAAAGGATTATACGGTCCTCAGGGGACCGGCGGGCTTTACA
TTGCTCCGGAATGGGAAAAAGTTTTAAAAACCCTGAAGGAAGGCGGTACCGGCGGGCATTCGGAGGAAGAGCTACCGCCG
GAAATTTTGCCTGATAAATACGAAAGTGGTACCCTCAATACGATTGGTATTGCAGGACTAAAAGCCGGGGTGGAGTTTGT
TTTAAAGATAGGTGTGGAGAAAATTTTTCAACATGAAAAGAAACTGACCCGGAAACTTTATCAGGGGTTAAAGGAGCTGG
GAGCGGAAATTTTGGGTCCGGATCCGGAAAACGACCGGGCACCGCTTGTGTCTTTTAATTTTCCCGGGGCCGATGCGGCA
ACGGTAAGCTTTATGTTAGATAAGCTTTACGATATAGCTACCCGGCCCGGACTTCATTGTGCTCCAAAAGCCCATGAAGT
TGCCGGCACTTTAGACCGGGGAGCCGTACGGGCAAGCTTTTCGTATTTTAATACCGAAGAAGAAGTAGAGGAATTTTTAG
AGGCAATAAAGGAGATAAAAGATGAATTATAA

Upstream 100 bases:

>100_bases
GAAAAATCACCATAGAATACTATTCGCCGGAGGAGTTGCAGCGGATTCTTGATTTATTGTATATCGAATAAACTCCAGTA
AGTTAAAAGAGGTGGAAAAA

Downstream 100 bases:

>100_bases
ATTGAGCCAAATTTTTTGGCTCTTTTTTTATTTGCCCCTTAGTTTAATGCCCAGAAAATCGAAAACGGAATACTTATAAG
TTTTACTTATAAAATTCATT

Product: cysteine desulfurase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MPTIYFDNSATTYPKPPEVLEAMIYFAEKVGANPGRGSHQRALKASQIILEAREAVKKLINGVSADRVIFTANATESLNL
ALKGLLQAGDHVIASPFEHNAVQRPLNRLRREGVEVSYLSSSPAGEIDPDEIKKLLKPNTRAVVVTHASNVLGCITPVAE
VGKICREAGVALIVDAAQSLGTIPVDVQSYNISLLAFTGHKGLYGPQGTGGLYIAPEWEKVLKTLKEGGTGGHSEEELPP
EILPDKYESGTLNTIGIAGLKAGVEFVLKIGVEKIFQHEKKLTRKLYQGLKELGAEILGPDPENDRAPLVSFNFPGADAA
TVSFMLDKLYDIATRPGLHCAPKAHEVAGTLDRGAVRASFSYFNTEEEVEEFLEAIKEIKDEL

Sequences:

>Translated_383_residues
MPTIYFDNSATTYPKPPEVLEAMIYFAEKVGANPGRGSHQRALKASQIILEAREAVKKLINGVSADRVIFTANATESLNL
ALKGLLQAGDHVIASPFEHNAVQRPLNRLRREGVEVSYLSSSPAGEIDPDEIKKLLKPNTRAVVVTHASNVLGCITPVAE
VGKICREAGVALIVDAAQSLGTIPVDVQSYNISLLAFTGHKGLYGPQGTGGLYIAPEWEKVLKTLKEGGTGGHSEEELPP
EILPDKYESGTLNTIGIAGLKAGVEFVLKIGVEKIFQHEKKLTRKLYQGLKELGAEILGPDPENDRAPLVSFNFPGADAA
TVSFMLDKLYDIATRPGLHCAPKAHEVAGTLDRGAVRASFSYFNTEEEVEEFLEAIKEIKDEL
>Mature_382_residues
PTIYFDNSATTYPKPPEVLEAMIYFAEKVGANPGRGSHQRALKASQIILEAREAVKKLINGVSADRVIFTANATESLNLA
LKGLLQAGDHVIASPFEHNAVQRPLNRLRREGVEVSYLSSSPAGEIDPDEIKKLLKPNTRAVVVTHASNVLGCITPVAEV
GKICREAGVALIVDAAQSLGTIPVDVQSYNISLLAFTGHKGLYGPQGTGGLYIAPEWEKVLKTLKEGGTGGHSEEELPPE
ILPDKYESGTLNTIGIAGLKAGVEFVLKIGVEKIFQHEKKLTRKLYQGLKELGAEILGPDPENDRAPLVSFNFPGADAAT
VSFMLDKLYDIATRPGLHCAPKAHEVAGTLDRGAVRASFSYFNTEEEVEEFLEAIKEIKDEL

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=394, Percent_Identity=31.2182741116751, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI156713448, Length=299, Percent_Identity=32.4414715719064, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1787970, Length=401, Percent_Identity=32.1695760598504, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI48994898, Length=392, Percent_Identity=30.8673469387755, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789175, Length=386, Percent_Identity=30.3108808290155, Blast_Score=143, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25143064, Length=392, Percent_Identity=29.0816326530612, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17533177, Length=345, Percent_Identity=25.7971014492754, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193211090, Length=390, Percent_Identity=24.6153846153846, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319831, Length=388, Percent_Identity=30.9278350515464, Blast_Score=162, Evalue=9e-41,
Organism=Drosophila melanogaster, GI20129463, Length=230, Percent_Identity=36.0869565217391, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41378; Mature: 41246

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTIYFDNSATTYPKPPEVLEAMIYFAEKVGANPGRGSHQRALKASQIILEAREAVKKLI
CCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NGVSADRVIFTANATESLNLALKGLLQAGDHVIASPFEHNAVQRPLNRLRREGVEVSYLS
CCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHCCCEEEEEC
SSPAGEIDPDEIKKLLKPNTRAVVVTHASNVLGCITPVAEVGKICREAGVALIVDAAQSL
CCCCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEECHHHC
GTIPVDVQSYNISLLAFTGHKGLYGPQGTGGLYIAPEWEKVLKTLKEGGTGGHSEEELPP
CCCEEEEEECEEEEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCH
EILPDKYESGTLNTIGIAGLKAGVEFVLKIGVEKIFQHEKKLTRKLYQGLKELGAEILGP
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPENDRAPLVSFNFPGADAATVSFMLDKLYDIATRPGLHCAPKAHEVAGTLDRGAVRASF
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
SYFNTEEEVEEFLEAIKEIKDEL
HHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTIYFDNSATTYPKPPEVLEAMIYFAEKVGANPGRGSHQRALKASQIILEAREAVKKLI
CEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NGVSADRVIFTANATESLNLALKGLLQAGDHVIASPFEHNAVQRPLNRLRREGVEVSYLS
CCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHCCCEEEEEC
SSPAGEIDPDEIKKLLKPNTRAVVVTHASNVLGCITPVAEVGKICREAGVALIVDAAQSL
CCCCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEECHHHC
GTIPVDVQSYNISLLAFTGHKGLYGPQGTGGLYIAPEWEKVLKTLKEGGTGGHSEEELPP
CCCEEEEEECEEEEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCH
EILPDKYESGTLNTIGIAGLKAGVEFVLKIGVEKIFQHEKKLTRKLYQGLKELGAEILGP
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPENDRAPLVSFNFPGADAATVSFMLDKLYDIATRPGLHCAPKAHEVAGTLDRGAVRASF
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
SYFNTEEEVEEFLEAIKEIKDEL
HHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]