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The map label for this gene is cobK [H]

Identifier: 78044761

GI number: 78044761

Start: 673445

End: 674221

Strand: Direct

Name: cobK [H]

Synonym: CHY_0765

Alternate gene names: 78044761

Gene position: 673445-674221 (Clockwise)

Preceding gene: 78042730

Following gene: 78042873

Centisome position: 28.04

GC content: 40.8

Gene sequence:

>777_bases
GTGATTTTATTGCTGGGAGGTACCAGTGAAAGTATTTTAATTGCCGATTTGCTCGAAAAAAAAGGTTTACCTTTTATTTT
ATCGGTGGCGTCAAATTTGGGCCTTATGCGGTTTAAAAAATATGAAAAACCTTTGCGGGCTGGAGTCCTGGATTTTCATG
GCCTTCTGGAGTTTGTTCAGAAAAATGGGATAAAGTTAATAATTGATGCTACCCATCCCTTTGCTAAAAATGCCAGTGAA
AATGCTATCAGGGCGGCCCAGGTATTAAATATACCCTATATCAGGTTTGAGCGCCCCAGGGATGAATTAAAAAATTCCCT
TATCATAGAGGCCATTGATTTAGAAGCTGCACTAAGAGAACTGCCGCAACTTGGTAAGCGTCCATTAATAACTGTGGGAG
TAAAAATGCTTCCGGAAATCATCAGAAAAAGTGCTGTTTTAGGGCAAAAGCCGGTAGTCAAAGTTTTGCCCCTAACGGAT
AATTTTACCCTTTTGGATGGTTTAGGAATTCCTCTCGAGGACCGGCTTTCCTTTTGGGGTCCAGGAAGCCGGGAGCTTAT
TTCTCAGCTAATTAAATTTTATTCCCTGACCGGTCTTTTGACCAAAGAAAGCGGTGATTTAGGAGGAGAAAGGGAAAAGG
TAGAAAGCTTTTTAAGTCAGAGTTTACCGGTAATTTTAATAAAACGTCCTGAGGTTTTTTACCCTCAATCGGTATCCACA
CTGGACCGGTTGGAAGAAATTTTAACATTGGAGGCGGAAAAATGGAAAAAGCAGTAG

Upstream 100 bases:

>100_bases
TTACCGAAGAGGATGCCGATATGCGCACGGTAATAATTATCGGAAATAGCCAGAGCTATTTTTATGAAAACTTTATTATT
ACACCCCGGGGGTATAAGTG

Downstream 100 bases:

>100_bases
TTTTGCTGGCTCACGGTTCCCGGGTGGCGCAAGCGGTGGAGAAATTTCGCGAAGTGGTAGGAAAGTTAAGGGAGCGCTTT
CCCTTCCGGCTCGAGGAGGC

Product: precorrin-6x reductase

Products: Precorrin 6A; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MILLLGGTSESILIADLLEKKGLPFILSVASNLGLMRFKKYEKPLRAGVLDFHGLLEFVQKNGIKLIIDATHPFAKNASE
NAIRAAQVLNIPYIRFERPRDELKNSLIIEAIDLEAALRELPQLGKRPLITVGVKMLPEIIRKSAVLGQKPVVKVLPLTD
NFTLLDGLGIPLEDRLSFWGPGSRELISQLIKFYSLTGLLTKESGDLGGEREKVESFLSQSLPVILIKRPEVFYPQSVST
LDRLEEILTLEAEKWKKQ

Sequences:

>Translated_258_residues
MILLLGGTSESILIADLLEKKGLPFILSVASNLGLMRFKKYEKPLRAGVLDFHGLLEFVQKNGIKLIIDATHPFAKNASE
NAIRAAQVLNIPYIRFERPRDELKNSLIIEAIDLEAALRELPQLGKRPLITVGVKMLPEIIRKSAVLGQKPVVKVLPLTD
NFTLLDGLGIPLEDRLSFWGPGSRELISQLIKFYSLTGLLTKESGDLGGEREKVESFLSQSLPVILIKRPEVFYPQSVST
LDRLEEILTLEAEKWKKQ
>Mature_258_residues
MILLLGGTSESILIADLLEKKGLPFILSVASNLGLMRFKKYEKPLRAGVLDFHGLLEFVQKNGIKLIIDATHPFAKNASE
NAIRAAQVLNIPYIRFERPRDELKNSLIIEAIDLEAALRELPQLGKRPLITVGVKMLPEIIRKSAVLGQKPVVKVLPLTD
NFTLLDGLGIPLEDRLSFWGPGSRELISQLIKFYSLTGLLTKESGDLGGEREKVESFLSQSLPVILIKRPEVFYPQSVST
LDRLEEILTLEAEKWKKQ

Specific function: Catalyzes the reduction of the macrocycle of cobalt- precorrin-6X into cobalt-precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: 1.3.1.54

Molecular weight: Translated: 28862; Mature: 28862

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLLGGTSESILIADLLEKKGLPFILSVASNLGLMRFKKYEKPLRAGVLDFHGLLEFVQ
CEEEEECCCCHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KNGIKLIIDATHPFAKNASENAIRAAQVLNIPYIRFERPRDELKNSLIIEAIDLEAALRE
HCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHHHCCCCEEEEHHHHHHHHH
LPQLGKRPLITVGVKMLPEIIRKSAVLGQKPVVKVLPLTDNFTLLDGLGIPLEDRLSFWG
HHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCHHHHHCCCC
PGSRELISQLIKFYSLTGLLTKESGDLGGEREKVESFLSQSLPVILIKRPEVFYPQSVST
CCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCEECCCCHHH
LDRLEEILTLEAEKWKKQ
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILLLGGTSESILIADLLEKKGLPFILSVASNLGLMRFKKYEKPLRAGVLDFHGLLEFVQ
CEEEEECCCCHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KNGIKLIIDATHPFAKNASENAIRAAQVLNIPYIRFERPRDELKNSLIIEAIDLEAALRE
HCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHHHCCCCEEEEHHHHHHHHH
LPQLGKRPLITVGVKMLPEIIRKSAVLGQKPVVKVLPLTDNFTLLDGLGIPLEDRLSFWG
HHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCHHHHHCCCC
PGSRELISQLIKFYSLTGLLTKESGDLGGEREKVESFLSQSLPVILIKRPEVFYPQSVST
CCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCEECCCCHHH
LDRLEEILTLEAEKWKKQ
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 6B; NADP+

Specific reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]