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The map label for this gene is prmA

Identifier: 78044697

GI number: 78044697

Start: 360904

End: 361821

Strand: Direct

Name: prmA

Synonym: CHY_0417

Alternate gene names: 78044697

Gene position: 360904-361821 (Clockwise)

Preceding gene: 78044215

Following gene: 78044093

Centisome position: 15.03

GC content: 41.07

Gene sequence:

>918_bases
GTGAAATATCTTGAAATTGCGGTGGAAGTGGAAAGCTGTTTCACTGAAACGGTAGCTGATATTTTTTGGGAATTTAATAC
CGGGGGGGTAAGTATTGAAGACCCCCTTTTGCTTTGGCAGTATATAAACGCTCAGATCTGGGATGCTTATGAATTTCCCG
ACAGTGTCTTAAAAGCGGAAAGGGCAACGGTACGGGCTTATTTTCCCTTAACGGAAAATATTAACACTCTGTTAAGCCAG
ATCAATGAAAGGCTTAAATCTCTGGGTATTCCTTTCAACCTTTATTTTCAGGAAGTTGACGAGGAAAGCTGGGCAAATAG
CTGGAAAAAATATTTTAAACCCGTTGAAGTAGGGGAGTTTTTAATAAAACCTACCTGGGAAAAGCTACCTTCGGGCAAAG
AAGATAAAAAGATAATAGAAATTGACCCGGGGATGGCTTTCGGAACAGGAACCCACGTTACCACCGCATTGGTTTTAGAG
GCCTTACCGAAATACGTTAGCCCGGGCAAAGTAGTGGTGGATGTTGGTACCGGTTCAGGAATATTGGCGATAGCTTCCGC
TTTGCTGGGAGCCGAGAAGATTTATGCCTTGGATATAGATCCGGTAGCAGTAAAAGTTGCCCGGGAAAATATTTCTATAA
ACCGCCTGGAAGATAAGATTACGGTGATAGAAAATGACCTTTTACATGGTTTTAACCAGACCGTTGACGTTATCATCGCT
AATATTATTGCGGCAGTAATTAAAGAGTTAGCTTTGGATGCCTACGAAAAATTAGCCACCGGTGGAATTTTTATTGGTTC
GGGAATTATTGTAGAAAGAGAAAAGGAAGTTATGGATAAACTTTTGGAAGTTGGTTTTAAAATTATTGAAAGAAAAAACA
GTGGTGGTTGGTGCCTTCTGGTTGCCAGAAAGGAGTAG

Upstream 100 bases:

>100_bases
AGGAGATATCCAAGCAAAAAGAGGAAACCTTTAAAGAAAAATTTAATAAGTTTAAAAACAAATTTGCGTTATAATTAAAT
AAAAAAGACGGGTGAGGCCT

Downstream 100 bases:

>100_bases
GGTGTAAATGCCGTACTTTTTTCTACCCCCTGGGCAGACCCAGGGGGATTATGCTTATCTTACCGGTGACGATGCTAAAC
ATGTAGCCAAGGTTTTAAGA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKYLEIAVEVESCFTETVADIFWEFNTGGVSIEDPLLLWQYINAQIWDAYEFPDSVLKAERATVRAYFPLTENINTLLSQ
INERLKSLGIPFNLYFQEVDEESWANSWKKYFKPVEVGEFLIKPTWEKLPSGKEDKKIIEIDPGMAFGTGTHVTTALVLE
ALPKYVSPGKVVVDVGTGSGILAIASALLGAEKIYALDIDPVAVKVARENISINRLEDKITVIENDLLHGFNQTVDVIIA
NIIAAVIKELALDAYEKLATGGIFIGSGIIVEREKEVMDKLLEVGFKIIERKNSGGWCLLVARKE

Sequences:

>Translated_305_residues
MKYLEIAVEVESCFTETVADIFWEFNTGGVSIEDPLLLWQYINAQIWDAYEFPDSVLKAERATVRAYFPLTENINTLLSQ
INERLKSLGIPFNLYFQEVDEESWANSWKKYFKPVEVGEFLIKPTWEKLPSGKEDKKIIEIDPGMAFGTGTHVTTALVLE
ALPKYVSPGKVVVDVGTGSGILAIASALLGAEKIYALDIDPVAVKVARENISINRLEDKITVIENDLLHGFNQTVDVIIA
NIIAAVIKELALDAYEKLATGGIFIGSGIIVEREKEVMDKLLEVGFKIIERKNSGGWCLLVARKE
>Mature_305_residues
MKYLEIAVEVESCFTETVADIFWEFNTGGVSIEDPLLLWQYINAQIWDAYEFPDSVLKAERATVRAYFPLTENINTLLSQ
INERLKSLGIPFNLYFQEVDEESWANSWKKYFKPVEVGEFLIKPTWEKLPSGKEDKKIIEIDPGMAFGTGTHVTTALVLE
ALPKYVSPGKVVVDVGTGSGILAIASALLGAEKIYALDIDPVAVKVARENISINRLEDKITVIENDLLHGFNQTVDVIIA
NIIAAVIKELALDAYEKLATGGIFIGSGIIVEREKEVMDKLLEVGFKIIERKNSGGWCLLVARKE

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=166, Percent_Identity=39.7590361445783, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_CARHZ (Q3AF06)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359278.1
- HSSP:   O60678
- ProteinModelPortal:   Q3AF06
- SMR:   Q3AF06
- STRING:   Q3AF06
- GeneID:   3727819
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0417
- NMPDR:   fig|246194.3.peg.750
- TIGR:   CHY_0417
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   VPEWEDY
- BioCyc:   CHYD246194:CHY_0417-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33987; Mature: 33987

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLEIAVEVESCFTETVADIFWEFNTGGVSIEDPLLLWQYINAQIWDAYEFPDSVLKAE
CCEEEEEEEHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHCCCEEECCCCCHHHHHHH
RATVRAYFPLTENINTLLSQINERLKSLGIPFNLYFQEVDEESWANSWKKYFKPVEVGEF
HHEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHHHHHHHHCCCHHHHHH
LIKPTWEKLPSGKEDKKIIEIDPGMAFGTGTHVTTALVLEALPKYVSPGKVVVDVGTGSG
HCCCCHHHCCCCCCCCEEEEECCCCEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
ILAIASALLGAEKIYALDIDPVAVKVARENISINRLEDKITVIENDLLHGFNQTVDVIIA
HHHHHHHHHCCCEEEEECCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIIAAVIKELALDAYEKLATGGIFIGSGIIVEREKEVMDKLLEVGFKIIERKNSGGWCLL
HHHHHHHHHHHHHHHHHHHCCCEEECCCEEEECHHHHHHHHHHHHHHHHEECCCCCEEEE
VARKE
EEECC
>Mature Secondary Structure
MKYLEIAVEVESCFTETVADIFWEFNTGGVSIEDPLLLWQYINAQIWDAYEFPDSVLKAE
CCEEEEEEEHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHCCCEEECCCCCHHHHHHH
RATVRAYFPLTENINTLLSQINERLKSLGIPFNLYFQEVDEESWANSWKKYFKPVEVGEF
HHEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHHHHHHHHCCCHHHHHH
LIKPTWEKLPSGKEDKKIIEIDPGMAFGTGTHVTTALVLEALPKYVSPGKVVVDVGTGSG
HCCCCHHHCCCCCCCCEEEEECCCCEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
ILAIASALLGAEKIYALDIDPVAVKVARENISINRLEDKITVIENDLLHGFNQTVDVIIA
HHHHHHHHHCCCEEEEECCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIIAAVIKELALDAYEKLATGGIFIGSGIIVEREKEVMDKLLEVGFKIIERKNSGGWCLL
HHHHHHHHHHHHHHHHHHHCCCEEECCCEEEECHHHHHHHHHHHHHHHHEECCCCCEEEE
VARKE
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA