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The map label for this gene is dnaQ [H]

Identifier: 78044638

GI number: 78044638

Start: 1822887

End: 1823555

Strand: Direct

Name: dnaQ [H]

Synonym: CHY_2036

Alternate gene names: 78044638

Gene position: 1822887-1823555 (Clockwise)

Preceding gene: 78043289

Following gene: 78044475

Centisome position: 75.91

GC content: 38.27

Gene sequence:

>669_bases
ATGATAAAATCTTTAAAAAAATTTTTAGAACAAAATAAAAACCCGCTTCGCACTAAAATTGAAACGATAAATGCCTTTTA
TCCTTACGACATTCCGCTTTTAAATTTAACCTATACGGTAATTGACCTGGAAACCACCGGCTTAAAACCCTTTCAGGGGG
ACGAAATTATCGCGATTGGTGCGGTAAAAATTATTAACGGCAACATCACCCGTCCAGCCTTTCATGCTTATGTCAACCCC
CAGCGGGAAATACCAGAAGTAGTCCAAAGATTAACCGGAATTAGTCCAAAAACGGTGCAAAACGCTCCTCCCCTTACTAA
TACCCTGACAACTTTATTAGATTTTGCCAGAAACTCGGTTATCGTTGGGCATTCGGTAAATTTTGACCTGGCTTTTTTAA
ATAAACATCTAAGTTCCTTAACCGGAAAAAAACTAACCCCCCGTCTCCTGGATACCGTGGATTTAGGAATATATCTCTTC
CCCCGGGAGCCAAACTATTCTTTAGAAAATTTTGCCCAAAAATTTGCCATAAGCCTCCAGGGAAGACACACAGCCCTGGG
AGATGCGGTAATTTGCGCTAAAGTTTTTCTGAATTTTTTAAAAATACTTGAGTTAAAAAATATAAATACTTGGTGGCAAC
TTTCACAAGAGATATATAAAGTCCTATAA

Upstream 100 bases:

>100_bases
ACCAAATGCTTTTAAAAGAAGCTTTAATTTACGCCCAGAAACTCCAGCAACTTACCGCCACCGCCTTCCGGGTAACCGCC
TTTTAGGGAGGAATCTCATC

Downstream 100 bases:

>100_bases
TATTTGACACTTCTCGCCTTTTCTCTCTGAAATTTTTCACTTTTCGCCTCCTCCCGAACCATATTGACAGCGAAATTTTT
TTGCAGTATATTTAAATTAG

Product: putative DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIKSLKKFLEQNKNPLRTKIETINAFYPYDIPLLNLTYTVIDLETTGLKPFQGDEIIAIGAVKIINGNITRPAFHAYVNP
QREIPEVVQRLTGISPKTVQNAPPLTNTLTTLLDFARNSVIVGHSVNFDLAFLNKHLSSLTGKKLTPRLLDTVDLGIYLF
PREPNYSLENFAQKFAISLQGRHTALGDAVICAKVFLNFLKILELKNINTWWQLSQEIYKVL

Sequences:

>Translated_222_residues
MIKSLKKFLEQNKNPLRTKIETINAFYPYDIPLLNLTYTVIDLETTGLKPFQGDEIIAIGAVKIINGNITRPAFHAYVNP
QREIPEVVQRLTGISPKTVQNAPPLTNTLTTLLDFARNSVIVGHSVNFDLAFLNKHLSSLTGKKLTPRLLDTVDLGIYLF
PREPNYSLENFAQKFAISLQGRHTALGDAVICAKVFLNFLKILELKNINTWWQLSQEIYKVL
>Mature_222_residues
MIKSLKKFLEQNKNPLRTKIETINAFYPYDIPLLNLTYTVIDLETTGLKPFQGDEIIAIGAVKIINGNITRPAFHAYVNP
QREIPEVVQRLTGISPKTVQNAPPLTNTLTTLLDFARNSVIVGHSVNFDLAFLNKHLSSLTGKKLTPRLLDTVDLGIYLF
PREPNYSLENFAQKFAISLQGRHTALGDAVICAKVFLNFLKILELKNINTWWQLSQEIYKVL

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786409, Length=170, Percent_Identity=30, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR000014
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25108; Mature: 25108

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKSLKKFLEQNKNPLRTKIETINAFYPYDIPLLNLTYTVIDLETTGLKPFQGDEIIAIG
CHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCEEEEE
AVKIINGNITRPAFHAYVNPQREIPEVVQRLTGISPKTVQNAPPLTNTLTTLLDFARNSV
EEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCE
IVGHSVNFDLAFLNKHLSSLTGKKLTPRLLDTVDLGIYLFPREPNYSLENFAQKFAISLQ
EEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCC
GRHTALGDAVICAKVFLNFLKILELKNINTWWQLSQEIYKVL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MIKSLKKFLEQNKNPLRTKIETINAFYPYDIPLLNLTYTVIDLETTGLKPFQGDEIIAIG
CHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCEEEEE
AVKIINGNITRPAFHAYVNPQREIPEVVQRLTGISPKTVQNAPPLTNTLTTLLDFARNSV
EEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCE
IVGHSVNFDLAFLNKHLSSLTGKKLTPRLLDTVDLGIYLFPREPNYSLENFAQKFAISLQ
EEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCC
GRHTALGDAVICAKVFLNFLKILELKNINTWWQLSQEIYKVL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]