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The map label for this gene is btuR [C]

Identifier: 78044451

GI number: 78044451

Start: 490851

End: 491432

Strand: Direct

Name: btuR [C]

Synonym: CHY_0571

Alternate gene names: 78044451

Gene position: 490851-491432 (Clockwise)

Preceding gene: 78044741

Following gene: 78043839

Centisome position: 20.44

GC content: 41.58

Gene sequence:

>582_bases
ATGCTCCATCTTTACTATGGGCCGGGAAAAGGAAAAAGTACCGCTGCCCTGGGAATGCTTTTAAGGGCTTACGGCCATGG
ACTTAAGGTGGCGTACTTTGGTTTTCTTAAGGGCGAAGGGTTTTACGGGGAATTTGAAACGCTTAAGAAATTGGACATTG
AAAAATATTGCCTTGGGAAAAGCTGCCCTTATGCTTCGTTAATTAAAACCGGAATAAAATCCTGTCCGGTAAAAGATAAC
TGCAACCTTTGCCACGTAAACCTTAAAAATCCGGACGAGGAAGATAAAAAGCTTTTCCTGGAAGGATTTTTCTGGGCCAA
AGCTCAAATTAACGCTTCACCCTACCGGCTGGTCGTGATGGATGAATTAGCTTTAGCGGCAAAGATTGATTTAATTGATG
AAGAGAGTTTAACATCCTTTCTTAAGGAGATAAAAAGAAAAGAAAATCTTGAAATGATTCTTACCGGACGGGAAGCGCCG
CTTTATCTAAAAGCTTATGCCGACTACGTTACTTATTTTGCCGAAGAGAAACATCCTTTTACTGAGCTTGGACTTACTTC
CCGAAAGGGGGTTGAGTTTTAG

Upstream 100 bases:

>100_bases
AAGAGGATATTAAACATTTAATTGAGAGGGTAAACCGCAAAGAAATTCCGCCGCAGGCGGCTTCTGAGGAGCTCTTAAAA
AGGTTGGGGGTAAGGAGGTA

Downstream 100 bases:

>100_bases
CCAAAAAATCAACCGTTTAACCTCAAAATTTTGCAGTTCACGGTAAGTTTATTGGAAGCAGCAGCTTTTTGGATTATAAC
TTAAAGTAGCAAAACATTTT

Product: putative cob(I)alamin adenosyltransferase

Products: triphosphate; adenosylcob(III)yrinic acid a,c-diamide; Adenosyl cobinamide

Alternate protein names: Cob(I)Yrinic Acid A C-Diamide Adenosyltransferase; ATPCorrinoid Adenosyltransferase BtuR/CobO/CobP; ATPCorrinoid Adenosyltransferase; Cob(I)Yrinate A C-Diamide Adenosyltransferase; ATPCorrinoid Adenosyltransferase Btur/Cobo/Cobp; Cobalamin Adenosyltransferase; Cob(I)Alamin Adenosyltransferase Related Protein; ATP Corrinoid Adenosyltransferase; Cob(I) Alamin Adenosyltransferase

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MLHLYYGPGKGKSTAALGMLLRAYGHGLKVAYFGFLKGEGFYGEFETLKKLDIEKYCLGKSCPYASLIKTGIKSCPVKDN
CNLCHVNLKNPDEEDKKLFLEGFFWAKAQINASPYRLVVMDELALAAKIDLIDEESLTSFLKEIKRKENLEMILTGREAP
LYLKAYADYVTYFAEEKHPFTELGLTSRKGVEF

Sequences:

>Translated_193_residues
MLHLYYGPGKGKSTAALGMLLRAYGHGLKVAYFGFLKGEGFYGEFETLKKLDIEKYCLGKSCPYASLIKTGIKSCPVKDN
CNLCHVNLKNPDEEDKKLFLEGFFWAKAQINASPYRLVVMDELALAAKIDLIDEESLTSFLKEIKRKENLEMILTGREAP
LYLKAYADYVTYFAEEKHPFTELGLTSRKGVEF
>Mature_193_residues
MLHLYYGPGKGKSTAALGMLLRAYGHGLKVAYFGFLKGEGFYGEFETLKKLDIEKYCLGKSCPYASLIKTGIKSCPVKDN
CNLCHVNLKNPDEEDKKLFLEGFFWAKAQINASPYRLVVMDELALAAKIDLIDEESLTSFLKEIKRKENLEMILTGREAP
LYLKAYADYVTYFAEEKHPFTELGLTSRKGVEF

Specific function: Required For Both De Novo Synthesis Of The Corrin Ring For The Assimilation Of Exogenous Corrinoids. Participates In The Adenosylation Of A Variety Of Incomplete And Complete Corrinoids (By Similarity). [C]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.17

Molecular weight: Translated: 21848; Mature: 21848

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLYYGPGKGKSTAALGMLLRAYGHGLKVAYFGFLKGEGFYGEFETLKKLDIEKYCLGK
CEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHCCHHHHHCCC
SCPYASLIKTGIKSCPVKDNCNLCHVNLKNPDEEDKKLFLEGFFWAKAQINASPYRLVVM
CCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHEEHHHEEEEEEEECCCCEEEEEE
DELALAAKIDLIDEESLTSFLKEIKRKENLEMILTGREAPLYLKAYADYVTYFAEEKHPF
ECHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHHHHHCCCCCH
TELGLTSRKGVEF
HHHCCCCCCCCCC
>Mature Secondary Structure
MLHLYYGPGKGKSTAALGMLLRAYGHGLKVAYFGFLKGEGFYGEFETLKKLDIEKYCLGK
CEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHCCHHHHHCCC
SCPYASLIKTGIKSCPVKDNCNLCHVNLKNPDEEDKKLFLEGFFWAKAQINASPYRLVVM
CCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHEEHHHEEEEEEEECCCCEEEEEE
DELALAAKIDLIDEESLTSFLKEIKRKENLEMILTGREAPLYLKAYADYVTYFAEEKHPF
ECHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHHHHHCCCCCH
TELGLTSRKGVEF
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)yrinic acid a,c-diamide; cobinamide

Specific reaction: (1) ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide; (2) ATP + cobinamide = triphosphate + adenosylcobinamide

General reaction: Adenosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA