Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 78044313

GI number: 78044313

Start: 255680

End: 257854

Strand: Direct

Name: rnr [H]

Synonym: CHY_0289

Alternate gene names: 78044313

Gene position: 255680-257854 (Clockwise)

Preceding gene: 78045070

Following gene: 78043075

Centisome position: 10.65

GC content: 45.61

Gene sequence:

>2175_bases
ATGAGAGAAAAAATTTTGGAGTATTTAATAAAAGCTAATTCTCCGCAATACCCCGATAAAATCATCGAAGGTCTTGGCCT
TACTGATGTTTCGGAAATAAAGAAATTGCTTGCGGCTTTAAGAGATTTGGAAAAAGAAGGAGAAGTGTATGTAACAAAGG
CCGGTAAATATGGCCTTCCCGAGCAAATGAACATGGTGCGGGGAAAGATTCAGGGGCATCCGAAAGGATTTGCCTTTTTA
ATACCCGAGGACCGGGAAAAGCAGGACGTATTTATTTCTCCTACCAATTTAAAAGGAGCAATGCATAACGACCGGGTACT
GGTAAGATACCTTCCCTTTTCCGATGGTAACCGTCCGGAAGGAGAAGTTGTCAAAATTTTAGAACGGGCCAATAAAACGG
TGGTGGGGAGTTTCTACCGGCGGCGGCATTATGGTTTGGTGGAGCCGGATGATGAGCGGATTACCGGTGCCATAATTATT
CCTCTGGGGAAAAAGGGAGTAAAAGCAAAGAACGGTGAAAAGGTGGTAGTGGAGATTACCGCTTATCCCCGGAAAGGAGA
ACTTCCTGAAGGGAAAATTATTGAGATTTTAGGCGATCCAGAAGATCAAGAGACGCGGTTAAAAGCCATCATCAAAAAAT
ACGGCCTTTTAGATTCCTTTAAACCGGAGACAATCAAAGAAGCCAGGGCTATTTCCCAGGAAATTGGCCCGGAAGAGCTA
AAAAGCCGCCGGGATTTAAGGGGAGAAATGATTGTTACCATTGATGATGAAGATGCCAAGGATTTAGACGATGCGGTTAG
TTTAAAAAAGCTTCCTAACGGTAATTACCAGTTGGGGGTACATATTGCCGACGTATCGTATTACGTGCGGGAAGGTTCGG
CTTTGGATAAAGAAGCGCTGGAACGGGGAACCAGTGTTTACCTAGCGGGTAAAGTGTTGCCGATGCTTCCCCCGGAGCTG
TCCAACGGAATTTGCAGCTTAAATCCCCGGGTGGACCGGTTGACCCTATCGGTGGTAATGGAAATTACTCCCGCCGGAGA
AGTGGTGAGTCATGAAATTTTTCCGTCGGTTATCAAGACCCGGGCCCGGCTTACCTACACCATTGTGAAAAAAGCTGTTT
TGGATAAAGATCCAAAAGCCCGGGAAGAGCTGGGGGATTTGGTGCCCATGTTGGAGGAAATGGCCAACCTTGCCATGATT
TTAAGAAAGCGCCGGCTTGAGCGGGGGGCAATTGATTTTGACCTTCCCGAAGCCAAAGTAATCTTAGATGATAAAGGGGA
AGTGGTGGATATCGTCCGGCGGGAGCGAAACATTGCTCACCAGCTAATTGAGGAGTTTATGTTAATAACTAACGAAACGG
TAGCGGAAAGATTTTTCTGGCAGGAAGTGCCGTTTTTGTACCGGATTCACGAAGATCCCGACGAAGGGAAAATCCAAAGC
TTAAAAGAGTTTTTAAGGCTTTTTGGTTATAACTTAAAAGGTGGCCGGGACGGGAAATACCACCCCCGCGAATTTCAACG
GCTTTTGGAAAAAGTGGCGGGAAGGAAGGAAGAAAGGGTAATCAATGCGGTCATGCTGCGGTCAATGAAACAGGCCCGTT
ATTCGGCGGAAAGAATCTGGCATTTTGGCTTAGCGGCGGAATACTACACCCACTTTACTTCACCCATTCGCCGTTATCCC
GATTTAATGATTCACCGGATAATCCGGGAAGTATTAGAAGGGAAACTTACCCCGCGGCGGGAAGCAAAACTTGCCAAAAT
TTTACCGAAGGTAGCCAAACATTCGTCGGAGATGGAACGCCGGGCCATGGAAGCGGAACGGGAATCGGTGGAAATGCGGA
TGGTCGAGTTTATGGTAGGTAAAGAAGGTACCGAATACGATGCTATAATTTCCGGGGTAACTTCTTTCGGCTTTTTTGTG
CAGTTGCCTAATTTAATTGAGGGGTTAGTGCGCGTATCCACTTTAGAGGATGATTACTATCTTTATGATGAAAAAAGTTA
TGCCCTTATTGGTCGGCGCACGAAAAAAGTGTTTCGTTTGGGTGATGAAGTGCGTGTAAGGTTGGTTAAAGTAAACACTG
TCTCAAGAGAAATTGATTTTATGCTTGTAAAAAAACTTGGGGAAAGTCCTGAAACTAATGAATCGGCGGAAGAAATTTTG
GAGCGGTTAACGTAA

Upstream 100 bases:

>100_bases
TAGGTTTATAGGCGGGGAAGGTGTACCCGCCTTTTGACATAATTGTAGTAAATTTAGGTGAAAATAAGTGACGAAGTGAC
GTTAAAAGGAGGAGTAATAA

Downstream 100 bases:

>100_bases
AAAAATTTCTGAGCAAAGGTTTTTGAAAATATGATATAATAATTTAAGTCATGTATGTTACGAGATTTTAAGGGGTATGT
TTTTATGGAAAAGATAATTG

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 724; Mature: 724

Protein sequence:

>724_residues
MREKILEYLIKANSPQYPDKIIEGLGLTDVSEIKKLLAALRDLEKEGEVYVTKAGKYGLPEQMNMVRGKIQGHPKGFAFL
IPEDREKQDVFISPTNLKGAMHNDRVLVRYLPFSDGNRPEGEVVKILERANKTVVGSFYRRRHYGLVEPDDERITGAIII
PLGKKGVKAKNGEKVVVEITAYPRKGELPEGKIIEILGDPEDQETRLKAIIKKYGLLDSFKPETIKEARAISQEIGPEEL
KSRRDLRGEMIVTIDDEDAKDLDDAVSLKKLPNGNYQLGVHIADVSYYVREGSALDKEALERGTSVYLAGKVLPMLPPEL
SNGICSLNPRVDRLTLSVVMEITPAGEVVSHEIFPSVIKTRARLTYTIVKKAVLDKDPKAREELGDLVPMLEEMANLAMI
LRKRRLERGAIDFDLPEAKVILDDKGEVVDIVRRERNIAHQLIEEFMLITNETVAERFFWQEVPFLYRIHEDPDEGKIQS
LKEFLRLFGYNLKGGRDGKYHPREFQRLLEKVAGRKEERVINAVMLRSMKQARYSAERIWHFGLAAEYYTHFTSPIRRYP
DLMIHRIIREVLEGKLTPRREAKLAKILPKVAKHSSEMERRAMEAERESVEMRMVEFMVGKEGTEYDAIISGVTSFGFFV
QLPNLIEGLVRVSTLEDDYYLYDEKSYALIGRRTKKVFRLGDEVRVRLVKVNTVSREIDFMLVKKLGESPETNESAEEIL
ERLT

Sequences:

>Translated_724_residues
MREKILEYLIKANSPQYPDKIIEGLGLTDVSEIKKLLAALRDLEKEGEVYVTKAGKYGLPEQMNMVRGKIQGHPKGFAFL
IPEDREKQDVFISPTNLKGAMHNDRVLVRYLPFSDGNRPEGEVVKILERANKTVVGSFYRRRHYGLVEPDDERITGAIII
PLGKKGVKAKNGEKVVVEITAYPRKGELPEGKIIEILGDPEDQETRLKAIIKKYGLLDSFKPETIKEARAISQEIGPEEL
KSRRDLRGEMIVTIDDEDAKDLDDAVSLKKLPNGNYQLGVHIADVSYYVREGSALDKEALERGTSVYLAGKVLPMLPPEL
SNGICSLNPRVDRLTLSVVMEITPAGEVVSHEIFPSVIKTRARLTYTIVKKAVLDKDPKAREELGDLVPMLEEMANLAMI
LRKRRLERGAIDFDLPEAKVILDDKGEVVDIVRRERNIAHQLIEEFMLITNETVAERFFWQEVPFLYRIHEDPDEGKIQS
LKEFLRLFGYNLKGGRDGKYHPREFQRLLEKVAGRKEERVINAVMLRSMKQARYSAERIWHFGLAAEYYTHFTSPIRRYP
DLMIHRIIREVLEGKLTPRREAKLAKILPKVAKHSSEMERRAMEAERESVEMRMVEFMVGKEGTEYDAIISGVTSFGFFV
QLPNLIEGLVRVSTLEDDYYLYDEKSYALIGRRTKKVFRLGDEVRVRLVKVNTVSREIDFMLVKKLGESPETNESAEEIL
ERLT
>Mature_724_residues
MREKILEYLIKANSPQYPDKIIEGLGLTDVSEIKKLLAALRDLEKEGEVYVTKAGKYGLPEQMNMVRGKIQGHPKGFAFL
IPEDREKQDVFISPTNLKGAMHNDRVLVRYLPFSDGNRPEGEVVKILERANKTVVGSFYRRRHYGLVEPDDERITGAIII
PLGKKGVKAKNGEKVVVEITAYPRKGELPEGKIIEILGDPEDQETRLKAIIKKYGLLDSFKPETIKEARAISQEIGPEEL
KSRRDLRGEMIVTIDDEDAKDLDDAVSLKKLPNGNYQLGVHIADVSYYVREGSALDKEALERGTSVYLAGKVLPMLPPEL
SNGICSLNPRVDRLTLSVVMEITPAGEVVSHEIFPSVIKTRARLTYTIVKKAVLDKDPKAREELGDLVPMLEEMANLAMI
LRKRRLERGAIDFDLPEAKVILDDKGEVVDIVRRERNIAHQLIEEFMLITNETVAERFFWQEVPFLYRIHEDPDEGKIQS
LKEFLRLFGYNLKGGRDGKYHPREFQRLLEKVAGRKEERVINAVMLRSMKQARYSAERIWHFGLAAEYYTHFTSPIRRYP
DLMIHRIIREVLEGKLTPRREAKLAKILPKVAKHSSEMERRAMEAERESVEMRMVEFMVGKEGTEYDAIISGVTSFGFFV
QLPNLIEGLVRVSTLEDDYYLYDEKSYALIGRRTKKVFRLGDEVRVRLVKVNTVSREIDFMLVKKLGESPETNESAEEIL
ERLT

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=590, Percent_Identity=30.1694915254237, Blast_Score=230, Evalue=4e-60,
Organism=Homo sapiens, GI190014625, Length=590, Percent_Identity=30.1694915254237, Blast_Score=229, Evalue=5e-60,
Organism=Homo sapiens, GI134288890, Length=565, Percent_Identity=30.4424778761062, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI219521928, Length=560, Percent_Identity=28.2142857142857, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI19115966, Length=574, Percent_Identity=27.7003484320557, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI156105695, Length=457, Percent_Identity=22.9759299781182, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI156105693, Length=465, Percent_Identity=23.010752688172, Blast_Score=81, Evalue=4e-15,
Organism=Escherichia coli, GI87082383, Length=712, Percent_Identity=39.747191011236, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI1787542, Length=615, Percent_Identity=28.4552845528455, Blast_Score=174, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17553506, Length=498, Percent_Identity=29.1164658634538, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI212645896, Length=493, Percent_Identity=29.6146044624746, Blast_Score=195, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6324552, Length=597, Percent_Identity=29.6482412060301, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6320499, Length=425, Percent_Identity=25.6470588235294, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6323943, Length=426, Percent_Identity=23.7089201877934, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24649634, Length=548, Percent_Identity=30.1094890510949, Blast_Score=220, Evalue=4e-57,
Organism=Drosophila melanogaster, GI19922976, Length=577, Percent_Identity=28.5961871750433, Blast_Score=192, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24654597, Length=577, Percent_Identity=28.5961871750433, Blast_Score=192, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24654592, Length=577, Percent_Identity=28.5961871750433, Blast_Score=191, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 82869; Mature: 82869

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREKILEYLIKANSPQYPDKIIEGLGLTDVSEIKKLLAALRDLEKEGEVYVTKAGKYGLP
CHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
EQMNMVRGKIQGHPKGFAFLIPEDREKQDVFISPTNLKGAMHNDRVLVRYLPFSDGNRPE
HHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCH
GEVVKILERANKTVVGSFYRRRHYGLVEPDDERITGAIIIPLGKKGVKAKNGEKVVVEIT
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEE
AYPRKGELPEGKIIEILGDPEDQETRLKAIIKKYGLLDSFKPETIKEARAISQEIGPEEL
ECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHH
KSRRDLRGEMIVTIDDEDAKDLDDAVSLKKLPNGNYQLGVHIADVSYYVREGSALDKEAL
HHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEEEHHHHHHCCCCCCHHHH
ERGTSVYLAGKVLPMLPPELSNGICSLNPRVDRLTLSVVMEITPAGEVVSHEIFPSVIKT
HCCCEEEEECCCCCCCCHHHCCCEEECCCCHHHEEEEHHEEECCCCHHHHHHHHHHHHHH
RARLTYTIVKKAVLDKDPKAREELGDLVPMLEEMANLAMILRKRRLERGAIDFDLPEAKV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
ILDDKGEVVDIVRRERNIAHQLIEEFMLITNETVAERFFWQEVPFLYRIHEDPDEGKIQS
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEECCCCCCCHHHH
LKEFLRLFGYNLKGGRDGKYHPREFQRLLEKVAGRKEERVINAVMLRSMKQARYSAERIW
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
HFGLAAEYYTHFTSPIRRYPDLMIHRIIREVLEGKLTPRREAKLAKILPKVAKHSSEMER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAMEAERESVEMRMVEFMVGKEGTEYDAIISGVTSFGFFVQLPNLIEGLVRVSTLEDDYY
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCEE
LYDEKSYALIGRRTKKVFRLGDEVRVRLVKVNTVSREIDFMLVKKLGESPETNESAEEIL
EECCCCHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ERLT
HHCC
>Mature Secondary Structure
MREKILEYLIKANSPQYPDKIIEGLGLTDVSEIKKLLAALRDLEKEGEVYVTKAGKYGLP
CHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
EQMNMVRGKIQGHPKGFAFLIPEDREKQDVFISPTNLKGAMHNDRVLVRYLPFSDGNRPE
HHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCCH
GEVVKILERANKTVVGSFYRRRHYGLVEPDDERITGAIIIPLGKKGVKAKNGEKVVVEIT
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEE
AYPRKGELPEGKIIEILGDPEDQETRLKAIIKKYGLLDSFKPETIKEARAISQEIGPEEL
ECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHH
KSRRDLRGEMIVTIDDEDAKDLDDAVSLKKLPNGNYQLGVHIADVSYYVREGSALDKEAL
HHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEEEHHHHHHCCCCCCHHHH
ERGTSVYLAGKVLPMLPPELSNGICSLNPRVDRLTLSVVMEITPAGEVVSHEIFPSVIKT
HCCCEEEEECCCCCCCCHHHCCCEEECCCCHHHEEEEHHEEECCCCHHHHHHHHHHHHHH
RARLTYTIVKKAVLDKDPKAREELGDLVPMLEEMANLAMILRKRRLERGAIDFDLPEAKV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
ILDDKGEVVDIVRRERNIAHQLIEEFMLITNETVAERFFWQEVPFLYRIHEDPDEGKIQS
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEECCCCCCCHHHH
LKEFLRLFGYNLKGGRDGKYHPREFQRLLEKVAGRKEERVINAVMLRSMKQARYSAERIW
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
HFGLAAEYYTHFTSPIRRYPDLMIHRIIREVLEGKLTPRREAKLAKILPKVAKHSSEMER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAMEAERESVEMRMVEFMVGKEGTEYDAIISGVTSFGFFVQLPNLIEGLVRVSTLEDDYY
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCEE
LYDEKSYALIGRRTKKVFRLGDEVRVRLVKVNTVSREIDFMLVKKLGESPETNESAEEIL
EECCCCHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ERLT
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]