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The map label for this gene is mreC [H]

Identifier: 78044174

GI number: 78044174

Start: 298386

End: 299207

Strand: Direct

Name: mreC [H]

Synonym: CHY_0343

Alternate gene names: 78044174

Gene position: 298386-299207 (Clockwise)

Preceding gene: 78044889

Following gene: 78043106

Centisome position: 12.42

GC content: 45.86

Gene sequence:

>822_bases
TTGGCTAAGAGGTACTGGGGCAAGACTCTTTTAATTGGGGTATTGCTGGCGGTGCTCCTCCTGTCTCTTGCCCGCTATAC
AACCAAACAGCTTCCCTTTTTTTCCGAAGTTAAATCCGGACTTAAAGACTTGACTTACCCTATTGCCCGGGCGGTTAGTT
TTCTCTGGGATGGGGTTGGCAATGTTACCCAATACTTTAAGGATATTAATGAGCTAAGGCGGGAAAAAGATAGACTTCTT
CAGGAAAATACTGCTTTAAAATACCAGTTAAATCGCTTACAAGAAGTAGAGAGGGAAAATCTGCGGCTTAAAGCACTGCT
GGGCTACAGTCGGGAACACCCAAATTTTAAACTTATTGTGGCCAAAATTATCGAGCGGGACCCGGCAAGCTGGTATAAGT
CTTTTACGGTTAATCAGGGAAAAAGTTCTGGGATCAGGAAAGATATGCCGGTTTTGGACCAAAACGGTTTGGTTGGCCGG
ATGATGAATGTGGCCGCTTTAAACGGTGAAGTATTGCTAATTACCGACCCACGGAGCAGTGTGGCGGCGGTCACTTATCC
GGGAAGGGTGCCGGGGATAATAAAAGGAACGGCTTTATCCTCCGAGCTTATTATGGATAACATTCCGTTAAATCTTGAAG
TTCGTACCGGAGAGAAGGTGCTTACCTCCGGTCAGGGAGGAGTATTTCCCGCAGGTATACCTATCGGGTACGTTGTAAGT
GTAACCAAAGATCCATCGGGGTTGGTGCAGGTGGCGAAAGTTCGTCCTTACGTTGATTTTGACCGGTTAGAGGAAGTATT
TATTTTAAAAGGCAGTCGTTAA

Upstream 100 bases:

>100_bases
ATTGCGTAGCTTACGGTACCGGCAAAGCTTTGGAAAACCTCAATGTTTTAAGAAATGTTTTAAAGACCCCTAAAAAATCC
ATAAAAGAGGCGTGATATAG

Downstream 100 bases:

>100_bases
CACCTGGGGGCAATGGTATGTCTAATCTAAAGGCTATGCTGTATTTTTTATTTTTTTATATAATAGCCCAAACGGTTTTT
AGCCGGCTGGCGGTAAATGG

Product: cell shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MAKRYWGKTLLIGVLLAVLLLSLARYTTKQLPFFSEVKSGLKDLTYPIARAVSFLWDGVGNVTQYFKDINELRREKDRLL
QENTALKYQLNRLQEVERENLRLKALLGYSREHPNFKLIVAKIIERDPASWYKSFTVNQGKSSGIRKDMPVLDQNGLVGR
MMNVAALNGEVLLITDPRSSVAAVTYPGRVPGIIKGTALSSELIMDNIPLNLEVRTGEKVLTSGQGGVFPAGIPIGYVVS
VTKDPSGLVQVAKVRPYVDFDRLEEVFILKGSR

Sequences:

>Translated_273_residues
MAKRYWGKTLLIGVLLAVLLLSLARYTTKQLPFFSEVKSGLKDLTYPIARAVSFLWDGVGNVTQYFKDINELRREKDRLL
QENTALKYQLNRLQEVERENLRLKALLGYSREHPNFKLIVAKIIERDPASWYKSFTVNQGKSSGIRKDMPVLDQNGLVGR
MMNVAALNGEVLLITDPRSSVAAVTYPGRVPGIIKGTALSSELIMDNIPLNLEVRTGEKVLTSGQGGVFPAGIPIGYVVS
VTKDPSGLVQVAKVRPYVDFDRLEEVFILKGSR
>Mature_272_residues
AKRYWGKTLLIGVLLAVLLLSLARYTTKQLPFFSEVKSGLKDLTYPIARAVSFLWDGVGNVTQYFKDINELRREKDRLLQ
ENTALKYQLNRLQEVERENLRLKALLGYSREHPNFKLIVAKIIERDPASWYKSFTVNQGKSSGIRKDMPVLDQNGLVGRM
MNVAALNGEVLLITDPRSSVAAVTYPGRVPGIIKGTALSSELIMDNIPLNLEVRTGEKVLTSGQGGVFPAGIPIGYVVSV
TKDPSGLVQVAKVRPYVDFDRLEEVFILKGSR

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family [H]

Homologues:

Organism=Escherichia coli, GI1789648, Length=253, Percent_Identity=28.4584980237154, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007221
- InterPro:   IPR005223 [H]

Pfam domain/function: PF04085 MreC [H]

EC number: NA

Molecular weight: Translated: 30467; Mature: 30336

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRYWGKTLLIGVLLAVLLLSLARYTTKQLPFFSEVKSGLKDLTYPIARAVSFLWDGVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHH
NVTQYFKDINELRREKDRLLQENTALKYQLNRLQEVERENLRLKALLGYSREHPNFKLIV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEHH
AKIIERDPASWYKSFTVNQGKSSGIRKDMPVLDQNGLVGRMMNVAALNGEVLLITDPRSS
HHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEECCCEEEEECCCCC
VAAVTYPGRVPGIIKGTALSSELIMDNIPLNLEVRTGEKVLTSGQGGVFPAGIPIGYVVS
EEEEECCCCCCCEEECCCCCHHHHHCCCCCEEEEECCCHHEECCCCCCEECCCCEEEEEE
VTKDPSGLVQVAKVRPYVDFDRLEEVFILKGSR
ECCCCHHHHHHHHHCCCCCHHHHCEEEEEECCC
>Mature Secondary Structure 
AKRYWGKTLLIGVLLAVLLLSLARYTTKQLPFFSEVKSGLKDLTYPIARAVSFLWDGVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHH
NVTQYFKDINELRREKDRLLQENTALKYQLNRLQEVERENLRLKALLGYSREHPNFKLIV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEHH
AKIIERDPASWYKSFTVNQGKSSGIRKDMPVLDQNGLVGRMMNVAALNGEVLLITDPRSS
HHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEECCCEEEEECCCCC
VAAVTYPGRVPGIIKGTALSSELIMDNIPLNLEVRTGEKVLTSGQGGVFPAGIPIGYVVS
EEEEECCCCCCCEEECCCCCHHHHHCCCCCEEEEECCCHHEECCCCCCEECCCCEEEEEE
VTKDPSGLVQVAKVRPYVDFDRLEEVFILKGSR
ECCCCHHHHHHHHHCCCCCHHHHCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]