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The map label for this gene is atoC [H]

Identifier: 78044142

GI number: 78044142

Start: 635756

End: 636139

Strand: Direct

Name: atoC [H]

Synonym: CHY_0719

Alternate gene names: 78044142

Gene position: 635756-636139 (Clockwise)

Preceding gene: 78043381

Following gene: 78044478

Centisome position: 26.47

GC content: 38.8

Gene sequence:

>384_bases
ATGCAGGTTTTGGTTGCCGATGACCAGCCAGGGATCAGAATGCTTTTAAAAATTATTTTGGAGCAGATGGGCTTTGGGGT
ACATGAAGCAAAAAACGGCCAGGAAGCAGTGGAAAAAGCTCTAAATATTCGACCGGGTCTAATTATTATGGATATGCGCA
TGCCCTATAAAAGCGGTGATGAAGCCATTGCGGAAATTCACTCTTTTCTTCCGCAGACAGATTTTATTGTAATGACTGCT
TATACAGCTCCCGAAGTGTTGGAAAGGATTGATAGAAAAAAAGTTTTTGAGGTTGTTGCCAAACCTTTTGATGTTGAGGA
GTTTAAGATGATACTTAATAAATACCTCAAAGAAAAATTTCCCTGGAAATATTCTTTTGTGTAG

Upstream 100 bases:

>100_bases
GAAAACGACAAGTTTTTTACCAGAGGAAAAGGATTTTTTATATCTTTGACGAAAAAAGTATATGGTAATAAATGGGGATG
GGGGGAAACCCGTGGATATC

Downstream 100 bases:

>100_bases
AAATCTTTCTAAATTTAATTTAAAATGAAGGAACAGGGGGAGTGGTGTTATGGGAGATATTAAATGCGCGAACTGTGAGC
TTTGCGGTCGGGAGGTACCA

Product: response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MQVLVADDQPGIRMLLKIILEQMGFGVHEAKNGQEAVEKALNIRPGLIIMDMRMPYKSGDEAIAEIHSFLPQTDFIVMTA
YTAPEVLERIDRKKVFEVVAKPFDVEEFKMILNKYLKEKFPWKYSFV

Sequences:

>Translated_127_residues
MQVLVADDQPGIRMLLKIILEQMGFGVHEAKNGQEAVEKALNIRPGLIIMDMRMPYKSGDEAIAEIHSFLPQTDFIVMTA
YTAPEVLERIDRKKVFEVVAKPFDVEEFKMILNKYLKEKFPWKYSFV
>Mature_127_residues
MQVLVADDQPGIRMLLKIILEQMGFGVHEAKNGQEAVEKALNIRPGLIIMDMRMPYKSGDEAIAEIHSFLPQTDFIVMTA
YTAPEVLERIDRKKVFEVVAKPFDVEEFKMILNKYLKEKFPWKYSFV

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=34.4827586206897, Blast_Score=80, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 14709; Mature: 14709

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVLVADDQPGIRMLLKIILEQMGFGVHEAKNGQEAVEKALNIRPGLIIMDMRMPYKSGD
CEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCH
EAIAEIHSFLPQTDFIVMTAYTAPEVLERIDRKKVFEVVAKPFDVEEFKMILNKYLKEKF
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
PWKYSFV
CCCCCCC
>Mature Secondary Structure
MQVLVADDQPGIRMLLKIILEQMGFGVHEAKNGQEAVEKALNIRPGLIIMDMRMPYKSGD
CEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCH
EAIAEIHSFLPQTDFIVMTAYTAPEVLERIDRKKVFEVVAKPFDVEEFKMILNKYLKEKF
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
PWKYSFV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]