Click here to switch to the map view.

The map label for this gene is thiN [H]

Identifier: 78044035

GI number: 78044035

Start: 198722

End: 199333

Strand: Direct

Name: thiN [H]

Synonym: CHY_0231

Alternate gene names: 78044035

Gene position: 198722-199333 (Clockwise)

Preceding gene: 78043984

Following gene: 78043552

Centisome position: 8.27

GC content: 46.08

Gene sequence:

>612_bases
ATGCGGGTTATAATTTTTGCCGGGGGTGAGGCCCCCGGCTTTTTACCGGATTTAACACCGGAGGATTACTTAATAGTGGC
CGATGGTGGGGCAAGGCATTTGCCCCCGGAGGTCATACCCGATCTTTTACTGGGGGATATGGACTCGCTTCCGAAAAACT
TGCAGGAAGAGTTTAAAAGAAAAGGGGTAAAGCTTAAAATTTATCCTGCCGAAAAAGATTTTACCGATTTAGAAGCAGCT
GTACAAACAGCGCAGGACCTGGATGCTTCCGAGGTTGTAGTGGTAGGAGGAACCGGGGGACGGAGCGACCACTTTTTTGC
AAATTTGCTACTTCTTGCTAAATGTAGCTGCCCGGTAACCTGGATTGGTCACGATTTTACCGGTTATCTAAATAAAAACC
CTCTTATTCTAAAAGGGAAACCCGGGCAGTTATTTTCGGTTATTCCCCTTACCGGAGAAGTTACCGGCCTTACTATCGAA
GGAGCTAAATACCCCCTTGTTGGGGCTAATTTATCCTGGGGGACTACTTTGGGGCTGTCAAATGAGTTTATAGCCGATAC
GGTCAGAATTTCCTGGGTGACCGGTAAATTAATACTACTGCAAATTTTTTGA

Upstream 100 bases:

>100_bases
GGCAATTTATAACGGTAGTTACCTGCTGCCGGAATTAATTTTAACCCTGGGGGCAGTTTACTTGCTGAAAATCTTTGAAC
GCTTGCGGAAGGTGACGTAA

Downstream 100 bases:

>100_bases
TTTGGGCATTTTTTTGGAACCTTACCGGAGTAACGGTAAGGTTTAATTATATCGAGGTAGCTAATAAATTTTTTCTAAAA
ATATTTCTGCTAAAAATAGC

Product: thiamine pyrophosphokinase

Products: NA

Alternate protein names: TPK; Thiamine diphosphokinase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MRVIIFAGGEAPGFLPDLTPEDYLIVADGGARHLPPEVIPDLLLGDMDSLPKNLQEEFKRKGVKLKIYPAEKDFTDLEAA
VQTAQDLDASEVVVVGGTGGRSDHFFANLLLLAKCSCPVTWIGHDFTGYLNKNPLILKGKPGQLFSVIPLTGEVTGLTIE
GAKYPLVGANLSWGTTLGLSNEFIADTVRISWVTGKLILLQIF

Sequences:

>Translated_203_residues
MRVIIFAGGEAPGFLPDLTPEDYLIVADGGARHLPPEVIPDLLLGDMDSLPKNLQEEFKRKGVKLKIYPAEKDFTDLEAA
VQTAQDLDASEVVVVGGTGGRSDHFFANLLLLAKCSCPVTWIGHDFTGYLNKNPLILKGKPGQLFSVIPLTGEVTGLTIE
GAKYPLVGANLSWGTTLGLSNEFIADTVRISWVTGKLILLQIF
>Mature_203_residues
MRVIIFAGGEAPGFLPDLTPEDYLIVADGGARHLPPEVIPDLLLGDMDSLPKNLQEEFKRKGVKLKIYPAEKDFTDLEAA
VQTAQDLDASEVVVVGGTGGRSDHFFANLLLLAKCSCPVTWIGHDFTGYLNKNPLILKGKPGQLFSVIPLTGEVTGLTIE
GAKYPLVGANLSWGTTLGLSNEFIADTVRISWVTGKLILLQIF

Specific function: Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate [H]

COG id: COG1564

COG function: function code H; Thiamine pyrophosphokinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine pyrophosphokinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006282
- InterPro:   IPR007373
- InterPro:   IPR007371 [H]

Pfam domain/function: PF04263 TPK_catalytic [H]

EC number: =2.7.6.2 [H]

Molecular weight: Translated: 21906; Mature: 21906

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIIFAGGEAPGFLPDLTPEDYLIVADGGARHLPPEVIPDLLLGDMDSLPKNLQEEFKR
CEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
KGVKLKIYPAEKDFTDLEAAVQTAQDLDASEVVVVGGTGGRSDHFFANLLLLAKCSCPVT
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEE
WIGHDFTGYLNKNPLILKGKPGQLFSVIPLTGEVTGLTIEGAKYPLVGANLSWGTTLGLS
EECCCEEEEECCCCEEEECCCCCEEEEEECCCCEEEEEECCCCCCEEECCCCCCEEECCC
NEFIADTVRISWVTGKLILLQIF
CCCEEEEEEEEEEECEEEEEEEC
>Mature Secondary Structure
MRVIIFAGGEAPGFLPDLTPEDYLIVADGGARHLPPEVIPDLLLGDMDSLPKNLQEEFKR
CEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
KGVKLKIYPAEKDFTDLEAAVQTAQDLDASEVVVVGGTGGRSDHFFANLLLLAKCSCPVT
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEE
WIGHDFTGYLNKNPLILKGKPGQLFSVIPLTGEVTGLTIEGAKYPLVGANLSWGTTLGLS
EECCCEEEEECCCCEEEECCCCCEEEEEECCCCEEEEEECCCCCCEEECCCCCCEEECCC
NEFIADTVRISWVTGKLILLQIF
CCCEEEEEEEEEEECEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]