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The map label for this gene is moeA [H]

Identifier: 78044011

GI number: 78044011

Start: 768486

End: 769745

Strand: Direct

Name: moeA [H]

Synonym: CHY_0867

Alternate gene names: 78044011

Gene position: 768486-769745 (Clockwise)

Preceding gene: 78043234

Following gene: 78044599

Centisome position: 32.0

GC content: 43.89

Gene sequence:

>1260_bases
ATGGAGACCAATGTAGCTTTAGAAAAAGCTTTAAATATGCTTTTGGCTTATGTTCCTAAACCCGGAACGGAGATTGTCGA
AATTTTAAAAAGTCAGAACCGGGTGCTGGCAGAAGACGTTTTAGCCGACATTATGGTACCTCCTTTTTCCCGTTCGCCCT
TGGATGGATTTGCTTTTAGAAGCAGTGATTCCCCGCGGGAAAAAGGGCAAAAGGTTCGGCTTAAAATTGTTGACTACCTT
CCCGCGGGAGTGCCGGCTACAAGGCCGGTAAACTCCGGTGAAGCGGTAAAACTTATGACCGGGGCCATGATTCCCGAAGG
AGCCGATGCGGTAGTCAAATTTGAAGATGTGGTGGAAGAAGACGGCTATGTAATTATCGATTTTCCGGTAAAGCCAGAGA
CAAATATCGTTAAAAAAGGGGAAGACTTTTTACCAGGTGACGTCATCATTGAAAAAGACCGGGTAATTAATGCCAATGCC
ATTTCTCTATTAGCGTTAGCCGGAAAAAAGAAAGTGTTGGTTTATAAAATACCTAAAGTTTATATTATTTGTACGGGCAG
TGAACTGGTGGATATTGAACAAATTCCCGGTCCGGGGAAAATTCGCAATACCAATTTATACAGTATCGGGGCATTGGTGG
CAAGGTCCGGAGGAGAGCCTGTTTTAGGCCGAATTGTGAACGATGATTTAAATTTAATTGCCCAAGAAATAAAACGAGGA
CTGGAAGTGGCCGATTTAGTGCTGACCACCGGGGGAGCGTCGGTGGGGGAATATGACTTGATAATTAAGGCTTTAGAAAG
TATCGGTGCCGAAATTTTATTCTGGAAAACCGATTTTAAACCCGGTACACCGGTGATTGGGGCAGTAGCTAATGGGAAAA
TAGTTATTGGTTTATCAGGAAATCCCCAGGCAGCTATGACTTCTTTCGAGCTAATTGCTTACCCCGTGATCAGAAAATTA
ACCGGTCGGCAAAATATTTACCATGCCCGGGTAAAAGCATTTTTGGACCACCCCTTTGATAAAACCCGGGGGCAACGGCG
TTTTGCCCGGGGCTATTGTTATTTAAAAGAAGGGGAGTTTAGGGTAAAAATCTTACCCTGGCTTTCCCCGGGCTCGTTAA
AAGGGGTTTTAAACTCCAACGCTTTGGTGGAAATCCCCAAAAATTGTCCGCCCTTAAAAACCAATGATCCCGTTAATATT
GTTTTAATTGAAGGAGGAAGCTTAAGTGCCTTTGATACTCCAGATAGTGGGCTATTCTAA

Upstream 100 bases:

>100_bases
CTTCCCGAGAATTTGCAGCGGGAAGAATTTCTTTTAAACGTTAATACCCCGGCGGATTATGAAAAACTGTTAAAAATATT
CAGTTTAAAGGAGTAGTTCA

Downstream 100 bases:

>100_bases
TTCTGGCAAGACCACCGTAGCAGAAAAATTAGTGCAGCTCTTTACCCGGCATGGGTTTAAAGTAGGGGTTGTAAAACACG
ATGTTCACGGCTTTGAAGTG

Product: putative molybdopterin biosynthesis protein MoeA

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
METNVALEKALNMLLAYVPKPGTEIVEILKSQNRVLAEDVLADIMVPPFSRSPLDGFAFRSSDSPREKGQKVRLKIVDYL
PAGVPATRPVNSGEAVKLMTGAMIPEGADAVVKFEDVVEEDGYVIIDFPVKPETNIVKKGEDFLPGDVIIEKDRVINANA
ISLLALAGKKKVLVYKIPKVYIICTGSELVDIEQIPGPGKIRNTNLYSIGALVARSGGEPVLGRIVNDDLNLIAQEIKRG
LEVADLVLTTGGASVGEYDLIIKALESIGAEILFWKTDFKPGTPVIGAVANGKIVIGLSGNPQAAMTSFELIAYPVIRKL
TGRQNIYHARVKAFLDHPFDKTRGQRRFARGYCYLKEGEFRVKILPWLSPGSLKGVLNSNALVEIPKNCPPLKTNDPVNI
VLIEGGSLSAFDTPDSGLF

Sequences:

>Translated_419_residues
METNVALEKALNMLLAYVPKPGTEIVEILKSQNRVLAEDVLADIMVPPFSRSPLDGFAFRSSDSPREKGQKVRLKIVDYL
PAGVPATRPVNSGEAVKLMTGAMIPEGADAVVKFEDVVEEDGYVIIDFPVKPETNIVKKGEDFLPGDVIIEKDRVINANA
ISLLALAGKKKVLVYKIPKVYIICTGSELVDIEQIPGPGKIRNTNLYSIGALVARSGGEPVLGRIVNDDLNLIAQEIKRG
LEVADLVLTTGGASVGEYDLIIKALESIGAEILFWKTDFKPGTPVIGAVANGKIVIGLSGNPQAAMTSFELIAYPVIRKL
TGRQNIYHARVKAFLDHPFDKTRGQRRFARGYCYLKEGEFRVKILPWLSPGSLKGVLNSNALVEIPKNCPPLKTNDPVNI
VLIEGGSLSAFDTPDSGLF
>Mature_419_residues
METNVALEKALNMLLAYVPKPGTEIVEILKSQNRVLAEDVLADIMVPPFSRSPLDGFAFRSSDSPREKGQKVRLKIVDYL
PAGVPATRPVNSGEAVKLMTGAMIPEGADAVVKFEDVVEEDGYVIIDFPVKPETNIVKKGEDFLPGDVIIEKDRVINANA
ISLLALAGKKKVLVYKIPKVYIICTGSELVDIEQIPGPGKIRNTNLYSIGALVARSGGEPVLGRIVNDDLNLIAQEIKRG
LEVADLVLTTGGASVGEYDLIIKALESIGAEILFWKTDFKPGTPVIGAVANGKIVIGLSGNPQAAMTSFELIAYPVIRKL
TGRQNIYHARVKAFLDHPFDKTRGQRRFARGYCYLKEGEFRVKILPWLSPGSLKGVLNSNALVEIPKNCPPLKTNDPVNI
VLIEGGSLSAFDTPDSGLF

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=346, Percent_Identity=33.2369942196532, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI10880983, Length=346, Percent_Identity=33.2369942196532, Blast_Score=158, Evalue=1e-38,
Organism=Escherichia coli, GI1787049, Length=349, Percent_Identity=31.8051575931232, Blast_Score=147, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI25147659, Length=338, Percent_Identity=32.2485207100592, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17562606, Length=388, Percent_Identity=23.1958762886598, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17136978, Length=366, Percent_Identity=28.1420765027322, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24638841, Length=366, Percent_Identity=28.1420765027322, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 45414; Mature: 45414

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METNVALEKALNMLLAYVPKPGTEIVEILKSQNRVLAEDVLADIMVPPFSRSPLDGFAFR
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEEC
SSDSPREKGQKVRLKIVDYLPAGVPATRPVNSGEAVKLMTGAMIPEGADAVVKFEDVVEE
CCCCHHHCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEHHHHCC
DGYVIIDFPVKPETNIVKKGEDFLPGDVIIEKDRVINANAISLLALAGKKKVLVYKIPKV
CCEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCEECCCCEEEEEECCCCEEEEEECCEE
YIICTGSELVDIEQIPGPGKIRNTNLYSIGALVARSGGEPVLGRIVNDDLNLIAQEIKRG
EEEECCCCEEEHCCCCCCCCEECCCEEEEHHHEECCCCCCEEEEEECCHHHHHHHHHHCC
LEVADLVLTTGGASVGEYDLIIKALESIGAEILFWKTDFKPGTPVIGAVANGKIVIGLSG
CCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCEEEEEECC
NPQAAMTSFELIAYPVIRKLTGRQNIYHARVKAFLDHPFDKTRGQRRFARGYCYLKEGEF
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCEEEEECCCE
RVKILPWLSPGSLKGVLNSNALVEIPKNCPPLKTNDPVNIVLIEGGSLSAFDTPDSGLF
EEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCC
>Mature Secondary Structure
METNVALEKALNMLLAYVPKPGTEIVEILKSQNRVLAEDVLADIMVPPFSRSPLDGFAFR
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEEC
SSDSPREKGQKVRLKIVDYLPAGVPATRPVNSGEAVKLMTGAMIPEGADAVVKFEDVVEE
CCCCHHHCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEHHHHCC
DGYVIIDFPVKPETNIVKKGEDFLPGDVIIEKDRVINANAISLLALAGKKKVLVYKIPKV
CCEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCEECCCCEEEEEECCCCEEEEEECCEE
YIICTGSELVDIEQIPGPGKIRNTNLYSIGALVARSGGEPVLGRIVNDDLNLIAQEIKRG
EEEECCCCEEEHCCCCCCCCEECCCEEEEHHHEECCCCCCEEEEEECCHHHHHHHHHHCC
LEVADLVLTTGGASVGEYDLIIKALESIGAEILFWKTDFKPGTPVIGAVANGKIVIGLSG
CCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCEEEEEECC
NPQAAMTSFELIAYPVIRKLTGRQNIYHARVKAFLDHPFDKTRGQRRFARGYCYLKEGEF
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCEEEEECCCE
RVKILPWLSPGSLKGVLNSNALVEIPKNCPPLKTNDPVNIVLIEGGSLSAFDTPDSGLF
EEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCEEEEEECCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA