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The map label for this gene is hyuA [H]

Identifier: 78043863

GI number: 78043863

Start: 1196487

End: 1198037

Strand: Direct

Name: hyuA [H]

Synonym: CHY_1337

Alternate gene names: 78043863

Gene position: 1196487-1198037 (Clockwise)

Preceding gene: 78044454

Following gene: 78042937

Centisome position: 49.82

GC content: 44.36

Gene sequence:

>1551_bases
ATGGAATATCGGATAGGCATTGATGTTGGGGGTACCAATACGGACGCGGTACTGGTTGATGAAAATATGAATTTAGTTGA
AAGCATCAAAGTACCAACTACAAAAGATGTTTCCACCGGCATATATGAAGCGTTGCATCGGGTTTTAGAAAAAAGTAAAG
TTGACCGGAAAAATATTAAATATGCTATGCTCGGTACTACCCATGCTACTAATGCGATTGTGGAACGCAAACGCCTTTGC
AAAACTGCAATTATTCGTATTGGCCGTCCGGCAACGGAAGCGATTGTCCCCTTAGTGGCATGGCCAAAGGATTTAGTTGA
GGCGGTAGGAAATCATTACTATTTAATTGCCGGTGGTCATGAATTTGATGGCCGGGAAATCAGTCCCCTGGATGAAGAAG
AATTAAGAAAAATTGCCCGGGAAATAAAGGGCAAAGTGGAAAGCGTTGCGGTGGTTTCGGTTTTTTCACCGGTAAACAAC
CAGCATGAACTAAGGGCCCGGGAAATACTGCAAGAAGTGCTTGGCGATATTCCAATTTCGCTATCTCATGAAATTGGTTC
AATTGGTCTTTTAGAAAGGGAAAATGCTACTGTTTTAAATGCTGCTTTGGTTGAAGTCGCTCGGACTACAGCCAGTGGAT
TTAAAGAAGCATTAGCGCGGGAAGGAGTTACCGATGCCAAAGTATTTCTTTGCCAGAACGATGGTACTTTAATGTCAATT
GATTATGCGATGCGGTATCCCATTTTAACCATTGCCTGCGGACCTACCAACAGTATCCGGGGTGCTGCCTTTTTAAGTAA
CTTAGAAAATGCTTTGGTGCTTGATGTGGGTGGGACTACCAGTGATATCGGTATCATCGCTCAAGGCTTTCCCAGGGAAT
CTTCAATTGCAGTAGAAATTGGAGGAGTAAGAACAAACTTCAGGATGCCCGACCTGATTTCCATTGGCCTTGGGGGTGGC
ACGATTATTCGGGAAGAAAACGGTGAGGTGAAAATTGGACCCGATAGCGTTGGCTACCGGATAACCGAAGAAGCAGTAGT
TTTCGGCGGTAAGACCGTTACAGCTACCGATATAGCCGTGCGCCTGGGATTGGCAGAGGTTGGTGATAAAGAAAAAGTAA
AGGATTTACCGTTAGAATTTGCTCAAAAAGCCTACCAGAAAATGCAGGAATTGGTTGAAGAAGCGATTGATAAAATAAAA
ACCAGCAAAGATCCTCAACCGCTCATTCTTGTAGGGGGAGGCAGCATAATTGTAAGCGATAAAATTAACGGCGTAAGTCA
GGTTGTGCGTCCGCAAAATTTTGGTGTAGCCAATGCCCTGGGGGCAGCTATTGCTCAGGTTAGCGGTGAAGTGGACCGGA
TTTATTCATTAAGCGAAATGAGCAGGGATGAGGCTTTAAATAATGCTAAACAGCTGGCAATAAATGAGGCTATTAAAGCT
GGAGCTAATCCGGATTCCGTGAACATTGTTCATGTAGAAGATATTCCGCTTGCCTATCTGCCCGGAAATGCGGTGAGAAT
CCGGGTAAAGGCTGCCGGGAATTTACTTTAA

Upstream 100 bases:

>100_bases
TGAAAAGGGTATTGCAACCGTTGGACCTCGCTACTTTGGCTACGATGTTGATTATGTACCTGTTGAAGAGCTCATTAAAG
GTTAAAGGAGGTCGGAAAAA

Downstream 100 bases:

>100_bases
ATTAATATAAACGGGGGGATTTTTAATGAAAATTAAGGTAATAATGCCGATTACTTCAGATGTTTTTAATGAGGAAATCA
GGGAAGAGTTTAAACATTAT

Product: hydantoinase/oxoprolinase family protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MEYRIGIDVGGTNTDAVLVDENMNLVESIKVPTTKDVSTGIYEALHRVLEKSKVDRKNIKYAMLGTTHATNAIVERKRLC
KTAIIRIGRPATEAIVPLVAWPKDLVEAVGNHYYLIAGGHEFDGREISPLDEEELRKIAREIKGKVESVAVVSVFSPVNN
QHELRAREILQEVLGDIPISLSHEIGSIGLLERENATVLNAALVEVARTTASGFKEALAREGVTDAKVFLCQNDGTLMSI
DYAMRYPILTIACGPTNSIRGAAFLSNLENALVLDVGGTTSDIGIIAQGFPRESSIAVEIGGVRTNFRMPDLISIGLGGG
TIIREENGEVKIGPDSVGYRITEEAVVFGGKTVTATDIAVRLGLAEVGDKEKVKDLPLEFAQKAYQKMQELVEEAIDKIK
TSKDPQPLILVGGGSIIVSDKINGVSQVVRPQNFGVANALGAAIAQVSGEVDRIYSLSEMSRDEALNNAKQLAINEAIKA
GANPDSVNIVHVEDIPLAYLPGNAVRIRVKAAGNLL

Sequences:

>Translated_516_residues
MEYRIGIDVGGTNTDAVLVDENMNLVESIKVPTTKDVSTGIYEALHRVLEKSKVDRKNIKYAMLGTTHATNAIVERKRLC
KTAIIRIGRPATEAIVPLVAWPKDLVEAVGNHYYLIAGGHEFDGREISPLDEEELRKIAREIKGKVESVAVVSVFSPVNN
QHELRAREILQEVLGDIPISLSHEIGSIGLLERENATVLNAALVEVARTTASGFKEALAREGVTDAKVFLCQNDGTLMSI
DYAMRYPILTIACGPTNSIRGAAFLSNLENALVLDVGGTTSDIGIIAQGFPRESSIAVEIGGVRTNFRMPDLISIGLGGG
TIIREENGEVKIGPDSVGYRITEEAVVFGGKTVTATDIAVRLGLAEVGDKEKVKDLPLEFAQKAYQKMQELVEEAIDKIK
TSKDPQPLILVGGGSIIVSDKINGVSQVVRPQNFGVANALGAAIAQVSGEVDRIYSLSEMSRDEALNNAKQLAINEAIKA
GANPDSVNIVHVEDIPLAYLPGNAVRIRVKAAGNLL
>Mature_516_residues
MEYRIGIDVGGTNTDAVLVDENMNLVESIKVPTTKDVSTGIYEALHRVLEKSKVDRKNIKYAMLGTTHATNAIVERKRLC
KTAIIRIGRPATEAIVPLVAWPKDLVEAVGNHYYLIAGGHEFDGREISPLDEEELRKIAREIKGKVESVAVVSVFSPVNN
QHELRAREILQEVLGDIPISLSHEIGSIGLLERENATVLNAALVEVARTTASGFKEALAREGVTDAKVFLCQNDGTLMSI
DYAMRYPILTIACGPTNSIRGAAFLSNLENALVLDVGGTTSDIGIIAQGFPRESSIAVEIGGVRTNFRMPDLISIGLGGG
TIIREENGEVKIGPDSVGYRITEEAVVFGGKTVTATDIAVRLGLAEVGDKEKVKDLPLEFAQKAYQKMQELVEEAIDKIK
TSKDPQPLILVGGGSIIVSDKINGVSQVVRPQNFGVANALGAAIAQVSGEVDRIYSLSEMSRDEALNNAKQLAINEAIKA
GANPDSVNIVHVEDIPLAYLPGNAVRIRVKAAGNLL

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Drosophila melanogaster, GI45550492, Length=456, Percent_Identity=26.9736842105263, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 55429; Mature: 55429

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRIGIDVGGTNTDAVLVDENMNLVESIKVPTTKDVSTGIYEALHRVLEKSKVDRKNIK
CCEEEEEEECCCCCCEEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCE
YAMLGTTHATNAIVERKRLCKTAIIRIGRPATEAIVPLVAWPKDLVEAVGNHYYLIAGGH
EEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHCCCCEEEEECCC
EFDGREISPLDEEELRKIAREIKGKVESVAVVSVFSPVNNQHELRAREILQEVLGDIPIS
CCCCCCCCCCCHHHHHHHHHHHCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEE
LSHEIGSIGLLERENATVLNAALVEVARTTASGFKEALAREGVTDAKVFLCQNDGTLMSI
ECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEE
DYAMRYPILTIACGPTNSIRGAAFLSNLENALVLDVGGTTSDIGIIAQGFPRESSIAVEI
EHEECCCEEEEEECCCCCCCHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCEEEEE
GGVRTNFRMPDLISIGLGGGTIIREENGEVKIGPDSVGYRITEEAVVFGGKTVTATDIAV
CCEEECCCCCCEEEEECCCCEEEEECCCCEEECCCCCCCEEECCEEEECCCEEEEEHHHE
RLGLAEVGDKEKVKDLPLEFAQKAYQKMQELVEEAIDKIKTSKDPQPLILVGGGSIIVSD
EECHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEC
KINGVSQVVRPQNFGVANALGAAIAQVSGEVDRIYSLSEMSRDEALNNAKQLAINEAIKA
CCCCHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GANPDSVNIVHVEDIPLAYLPGNAVRIRVKAAGNLL
CCCCCCEEEEEEECCCEEEECCCEEEEEEEECCCCC
>Mature Secondary Structure
MEYRIGIDVGGTNTDAVLVDENMNLVESIKVPTTKDVSTGIYEALHRVLEKSKVDRKNIK
CCEEEEEEECCCCCCEEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCE
YAMLGTTHATNAIVERKRLCKTAIIRIGRPATEAIVPLVAWPKDLVEAVGNHYYLIAGGH
EEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHCCCCEEEEECCC
EFDGREISPLDEEELRKIAREIKGKVESVAVVSVFSPVNNQHELRAREILQEVLGDIPIS
CCCCCCCCCCCHHHHHHHHHHHCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEE
LSHEIGSIGLLERENATVLNAALVEVARTTASGFKEALAREGVTDAKVFLCQNDGTLMSI
ECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEE
DYAMRYPILTIACGPTNSIRGAAFLSNLENALVLDVGGTTSDIGIIAQGFPRESSIAVEI
EHEECCCEEEEEECCCCCCCHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCEEEEE
GGVRTNFRMPDLISIGLGGGTIIREENGEVKIGPDSVGYRITEEAVVFGGKTVTATDIAV
CCEEECCCCCCEEEEECCCCEEEEECCCCEEECCCCCCCEEECCEEEECCCEEEEEHHHE
RLGLAEVGDKEKVKDLPLEFAQKAYQKMQELVEEAIDKIKTSKDPQPLILVGGGSIIVSD
EECHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEC
KINGVSQVVRPQNFGVANALGAAIAQVSGEVDRIYSLSEMSRDEALNNAKQLAINEAIKA
CCCCHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GANPDSVNIVHVEDIPLAYLPGNAVRIRVKAAGNLL
CCCCCCEEEEEEECCCEEEECCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]