Click here to switch to the map view.

The map label for this gene is clpX [H]

Identifier: 78043800

GI number: 78043800

Start: 281050

End: 282306

Strand: Direct

Name: clpX [H]

Synonym: CHY_0326

Alternate gene names: 78043800

Gene position: 281050-282306 (Clockwise)

Preceding gene: 78043074

Following gene: 78044193

Centisome position: 11.7

GC content: 42.48

Gene sequence:

>1257_bases
ATGTTTGATAAAAATCAGCTAAAGTGTTCCTTTTGCGGTAAGCATCAGGACCAGGTGCGAAAGCTCGTGGCTGGACCAGG
AGTTTATATATGTGATGAATGTATAGAACTGTGTAACGAAATTATTGAAGAAGAGTTAGCTGACGACCTGGAACTTTCCC
TTGAAGAACTTCCCAAACCCCAGGAGATTAAGGCTTATCTTGACCAGTATGTTATTGGTCAGGAGGAAGCTAAGAAAGTA
CTGGCGGTAGCAGTTTACAATCACTACAAACGGATTAACCTCGGTGGCAAAATTGATGATGTGGAGTTGTCCAAAAGCAA
CATCCTCATGCTGGGACCGACCGGTTCCGGGAAAACATTATTGGCCCAAACTTTAGCCAGATTTTTAAATGTACCTTTTG
CTATTGCTGATGCTACTGCCTTAACGGAAGCCGGTTATGTGGGAGAAGATGTGGAAAATATTCTTTTAAAACTTATTCAG
AACGCCGACTATGATATTGAGCGGGCTGAAAAGGGAATTGTTTATATTGACGAGATCGATAAGATAGCCCGGAAGTCGGA
GAATCCTTCTATTACCCGGGACGTATCCGGAGAGGGGGTCCAGCAAGCCCTTTTAAAAATCTTGGAAGGGACCATTGCTT
CCGTGCCGCCCCAGGGAGGGCGGAAGCACCCGCATCAGGAGTTTATTCAAATTGATACTACCAACATCCTCTTTATCGTT
GGTGGAGCTTTTGAAGGGATAGAGAAAATAATCCAAAACCGAATCGGGAAGAAAGGCCTGGGGTTTGGTGCGGAAATTAA
ACCCAAGAGAGAGCAAAATGTCGGCGAAATTTTAAAACATATTATGCCGGAAGATTTACTGAAATTTGGCTTAATCCCCG
AATTTGTTGGCCGTCTGCCAATTATTGTAACTTTGGATGCCCTGGATGAAGATGCTCTGGTCAGAATCCTTACCGAGCCC
AAGAATGCTTTAATAAAGCAGTATCAGAAACTGTTTGAATTAGATGGGGTAACTTTAGAATTTGAAGAAGATGCTTTAAG
GGCTATTGCCCAGAAAGCTATTAAAAGAAATACCGGGGCGCGGGGTCTTAGAGCTATTTTAGAAGAAGTTATGCTCGATG
TTATGTACGAAATACCATCCCGCAAAGACATTATTAAATGCATAGTAACGCGGGATGTTATTGAAAATAAAGCAAAACCC
ATTTTAGTAGGGACTGCAGAAAAGCGGAAAAAAGGTAAAAAAGAAGAGACGGCCTAA

Upstream 100 bases:

>100_bases
GATACCGAGCGCGACTTCTTTATGTCGGCTGCCGAAGCTAAAGAATACGGAATCATCGATGAGGTGATTACCGTTCGCAA
ATAATTTTTGAGGTGATGAA

Downstream 100 bases:

>100_bases
TTGGAGATTGGAGATTAGAGTTTGGAAGCTGGAAGATAATTTAAAGACAGAAGAAGTGGTTCTTTAAAAAAAGGACCACT
TCTTTTTTTATTGTTTAGAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MFDKNQLKCSFCGKHQDQVRKLVAGPGVYICDECIELCNEIIEEELADDLELSLEELPKPQEIKAYLDQYVIGQEEAKKV
LAVAVYNHYKRINLGGKIDDVELSKSNILMLGPTGSGKTLLAQTLARFLNVPFAIADATALTEAGYVGEDVENILLKLIQ
NADYDIERAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNILFIV
GGAFEGIEKIIQNRIGKKGLGFGAEIKPKREQNVGEILKHIMPEDLLKFGLIPEFVGRLPIIVTLDALDEDALVRILTEP
KNALIKQYQKLFELDGVTLEFEEDALRAIAQKAIKRNTGARGLRAILEEVMLDVMYEIPSRKDIIKCIVTRDVIENKAKP
ILVGTAEKRKKGKKEETA

Sequences:

>Translated_418_residues
MFDKNQLKCSFCGKHQDQVRKLVAGPGVYICDECIELCNEIIEEELADDLELSLEELPKPQEIKAYLDQYVIGQEEAKKV
LAVAVYNHYKRINLGGKIDDVELSKSNILMLGPTGSGKTLLAQTLARFLNVPFAIADATALTEAGYVGEDVENILLKLIQ
NADYDIERAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNILFIV
GGAFEGIEKIIQNRIGKKGLGFGAEIKPKREQNVGEILKHIMPEDLLKFGLIPEFVGRLPIIVTLDALDEDALVRILTEP
KNALIKQYQKLFELDGVTLEFEEDALRAIAQKAIKRNTGARGLRAILEEVMLDVMYEIPSRKDIIKCIVTRDVIENKAKP
ILVGTAEKRKKGKKEETA
>Mature_418_residues
MFDKNQLKCSFCGKHQDQVRKLVAGPGVYICDECIELCNEIIEEELADDLELSLEELPKPQEIKAYLDQYVIGQEEAKKV
LAVAVYNHYKRINLGGKIDDVELSKSNILMLGPTGSGKTLLAQTLARFLNVPFAIADATALTEAGYVGEDVENILLKLIQ
NADYDIERAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNILFIV
GGAFEGIEKIIQNRIGKKGLGFGAEIKPKREQNVGEILKHIMPEDLLKFGLIPEFVGRLPIIVTLDALDEDALVRILTEP
KNALIKQYQKLFELDGVTLEFEEDALRAIAQKAIKRNTGARGLRAILEEVMLDVMYEIPSRKDIIKCIVTRDVIENKAKP
ILVGTAEKRKKGKKEETA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=326, Percent_Identity=51.840490797546, Blast_Score=325, Evalue=4e-89,
Organism=Escherichia coli, GI1786642, Length=402, Percent_Identity=64.6766169154229, Blast_Score=542, Evalue=1e-155,
Organism=Escherichia coli, GI1790366, Length=213, Percent_Identity=35.6807511737089, Blast_Score=98, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=315, Percent_Identity=46.3492063492063, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=315, Percent_Identity=46.3492063492063, Blast_Score=275, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=417, Percent_Identity=38.6091127098321, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=40.2390438247012, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=412, Percent_Identity=41.2621359223301, Blast_Score=280, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=49.3710691823899, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=49.3710691823899, Blast_Score=309, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46539; Mature: 46539

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDKNQLKCSFCGKHQDQVRKLVAGPGVYICDECIELCNEIIEEELADDLELSLEELPKP
CCCCCCEEHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QEIKAYLDQYVIGQEEAKKVLAVAVYNHYKRINLGGKIDDVELSKSNILMLGPTGSGKTL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCEEEECCCCCCHHH
LAQTLARFLNVPFAIADATALTEAGYVGEDVENILLKLIQNADYDIERAEKGIVYIDEID
HHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCCCEEEHHHHH
KIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNILFIV
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEEECCEEEEEE
GGAFEGIEKIIQNRIGKKGLGFGAEIKPKREQNVGEILKHIMPEDLLKFGLIPEFVGRLP
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHCHHHHHHHCCCHHHHCCCC
IIVTLDALDEDALVRILTEPKNALIKQYQKLFELDGVTLEFEEDALRAIAQKAIKRNTGA
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCH
RGLRAILEEVMLDVMYEIPSRKDIIKCIVTRDVIENKAKPILVGTAEKRKKGKKEETA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCCCC
>Mature Secondary Structure
MFDKNQLKCSFCGKHQDQVRKLVAGPGVYICDECIELCNEIIEEELADDLELSLEELPKP
CCCCCCEEHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QEIKAYLDQYVIGQEEAKKVLAVAVYNHYKRINLGGKIDDVELSKSNILMLGPTGSGKTL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCEEEECCCCCCHHH
LAQTLARFLNVPFAIADATALTEAGYVGEDVENILLKLIQNADYDIERAEKGIVYIDEID
HHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCCCEEEHHHHH
KIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNILFIV
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEEECCEEEEEE
GGAFEGIEKIIQNRIGKKGLGFGAEIKPKREQNVGEILKHIMPEDLLKFGLIPEFVGRLP
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHCHHHHHHHCCCHHHHCCCC
IIVTLDALDEDALVRILTEPKNALIKQYQKLFELDGVTLEFEEDALRAIAQKAIKRNTGA
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCH
RGLRAILEEVMLDVMYEIPSRKDIIKCIVTRDVIENKAKPILVGTAEKRKKGKKEETA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA