Click here to switch to the map view.

The map label for this gene is gcp

Identifier: 78043782

GI number: 78043782

Start: 638031

End: 639032

Strand: Direct

Name: gcp

Synonym: CHY_0725

Alternate gene names: 78043782

Gene position: 638031-639032 (Clockwise)

Preceding gene: 78044332

Following gene: 78044212

Centisome position: 26.57

GC content: 45.71

Gene sequence:

>1002_bases
TTGGGTAAGGTTATCTTAGGCATTGAAACATCCTGCGATGAGACGGCAGTTTCCTTAGTGGAAGATGGTAGAAAGGTGTT
AATTTCTTTACTTTCTTCTCAGGTTGATCTTCACCGGCTGTACGGTGGTGTAGTACCCGAAATAGCATCCCGCAGGCATT
TAGAACTGATTTTTCCCCTGTTAGATGAAGCCTTTCGGAAATTCCCCAGGGAAAAGATAGCTGCGGTAGCGGTTACGTAC
GGTCCCGGGCTTGTAGGAGCTTTACTGGTTGGCCTTTCGGTAGCCAAAAGTTTAAGCTATGCCTTAAACGTTCCGTTAAT
TGGAGTTAATCACATGGAAGGGCATATTTTTGCCAATTTTCTTGAAGATGCAAATCCGGTTTTTCCGGCACTGGTGCTGG
TGGTTTCGGGGGGACATACCGATTTAATTTTCATGCGGGGCTTCGGGGATTACGAGCTTTTGGGGGAAACCATTGACGAT
GCTGCCGGGGAGTGTTTTGATAAAGTGGGCCGGGTATTAAACTTACCCTATCCCGCGGGGCCGGTTATTGACCGGTTGAG
TAAAAAGGGAAAACCCATTTATAAGTTTCCGGTAGCTCGTTTAAAAGAGGAAGGATATAACTTTAGCTTTAGCGGTTTAA
AAACTGCGGTAAGAGTTTTCCGGGAAAAAAATCCCGAGGCTAAAGTTGAAGACATTGCCGCGTCTTTTCAGGAAGCTCTG
GTCAGAGCTTTGGTGGAAAATACCGAAAAAGCTTTAAAAGAATGCATGCCGGCTAAGCTTTACTTAGCCGGTGGCGTTGC
GGCTAACTCAAGGTTGAGAGAAGAGTTTTTAAATCTTGGTAAAACCTATAATGTTCCGGTACATTTTCCTTCCCTTCAGT
ACTGTACCGATAATGCGGCAATGATTGCTGCCGCCGGTTATCACCGCTATCTTTCGGGGAAGTATGCACCGCTTAATTTA
AACGCCTACCCTTCGCTGATGCTCGGGGAGGAAAGATATTAA

Upstream 100 bases:

>100_bases
GAAGTTCGGTTTTAAACCAATAGGAATTAGAAAAAAATATTATTCCCGTCCTGAAGAAGATGCCATTGTAATGAGCCTTG
AGTTAAAGGAGGATTATTAA

Downstream 100 bases:

>100_bases
TCCTGTGGAAAACTACCTGTGGATAATGTGGATAACTTTGTTGATAACTTGAGATTAAAGGGTTTGTCCTGTTGATAACT
TTTAAAAATTTGTCAAAGTA

Product: O-sialoglycoprotein endopeptidase

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MGKVILGIETSCDETAVSLVEDGRKVLISLLSSQVDLHRLYGGVVPEIASRRHLELIFPLLDEAFRKFPREKIAAVAVTY
GPGLVGALLVGLSVAKSLSYALNVPLIGVNHMEGHIFANFLEDANPVFPALVLVVSGGHTDLIFMRGFGDYELLGETIDD
AAGECFDKVGRVLNLPYPAGPVIDRLSKKGKPIYKFPVARLKEEGYNFSFSGLKTAVRVFREKNPEAKVEDIAASFQEAL
VRALVENTEKALKECMPAKLYLAGGVAANSRLREEFLNLGKTYNVPVHFPSLQYCTDNAAMIAAAGYHRYLSGKYAPLNL
NAYPSLMLGEERY

Sequences:

>Translated_333_residues
MGKVILGIETSCDETAVSLVEDGRKVLISLLSSQVDLHRLYGGVVPEIASRRHLELIFPLLDEAFRKFPREKIAAVAVTY
GPGLVGALLVGLSVAKSLSYALNVPLIGVNHMEGHIFANFLEDANPVFPALVLVVSGGHTDLIFMRGFGDYELLGETIDD
AAGECFDKVGRVLNLPYPAGPVIDRLSKKGKPIYKFPVARLKEEGYNFSFSGLKTAVRVFREKNPEAKVEDIAASFQEAL
VRALVENTEKALKECMPAKLYLAGGVAANSRLREEFLNLGKTYNVPVHFPSLQYCTDNAAMIAAAGYHRYLSGKYAPLNL
NAYPSLMLGEERY
>Mature_332_residues
GKVILGIETSCDETAVSLVEDGRKVLISLLSSQVDLHRLYGGVVPEIASRRHLELIFPLLDEAFRKFPREKIAAVAVTYG
PGLVGALLVGLSVAKSLSYALNVPLIGVNHMEGHIFANFLEDANPVFPALVLVVSGGHTDLIFMRGFGDYELLGETIDDA
AGECFDKVGRVLNLPYPAGPVIDRLSKKGKPIYKFPVARLKEEGYNFSFSGLKTAVRVFREKNPEAKVEDIAASFQEALV
RALVENTEKALKECMPAKLYLAGGVAANSRLREEFLNLGKTYNVPVHFPSLQYCTDNAAMIAAAGYHRYLSGKYAPLNLN
AYPSLMLGEERY

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=344, Percent_Identity=34.3023255813954, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI8923380, Length=330, Percent_Identity=33.9393939393939, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1789445, Length=331, Percent_Identity=45.9214501510574, Blast_Score=280, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI71995670, Length=321, Percent_Identity=33.6448598130841, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17557464, Length=323, Percent_Identity=30.6501547987616, Blast_Score=134, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6320099, Length=351, Percent_Identity=33.6182336182336, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6322891, Length=297, Percent_Identity=32.996632996633, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI20129063, Length=345, Percent_Identity=34.4927536231884, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21357207, Length=339, Percent_Identity=32.1533923303835, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_CARHZ (Q3AE55)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359579.1
- STRING:   Q3AE55
- MEROPS:   M22.001
- GeneID:   3726638
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0725
- NMPDR:   fig|246194.3.peg.701
- TIGR:   CHY_0725
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- BioCyc:   CHYD246194:CHY_0725-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36441; Mature: 36309

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVILGIETSCDETAVSLVEDGRKVLISLLSSQVDLHRLYGGVVPEIASRRHLELIFPL
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHH
LDEAFRKFPREKIAAVAVTYGPGLVGALLVGLSVAKSLSYALNVPLIGVNHMEGHIFANF
HHHHHHHCCHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
LEDANPVFPALVLVVSGGHTDLIFMRGFGDYELLGETIDDAAGECFDKVGRVLNLPYPAG
HHCCCHHHHHHHHEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
PVIDRLSKKGKPIYKFPVARLKEEGYNFSFSGLKTAVRVFREKNPEAKVEDIAASFQEAL
HHHHHHHHCCCCEEECHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VRALVENTEKALKECMPAKLYLAGGVAANSRLREEFLNLGKTYNVPVHFPSLQYCTDNAA
HHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCEECCCEECCCHHEECCCCC
MIAAAGYHRYLSGKYAPLNLNAYPSLMLGEERY
EEEHHHHHHHHCCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
GKVILGIETSCDETAVSLVEDGRKVLISLLSSQVDLHRLYGGVVPEIASRRHLELIFPL
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHH
LDEAFRKFPREKIAAVAVTYGPGLVGALLVGLSVAKSLSYALNVPLIGVNHMEGHIFANF
HHHHHHHCCHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
LEDANPVFPALVLVVSGGHTDLIFMRGFGDYELLGETIDDAAGECFDKVGRVLNLPYPAG
HHCCCHHHHHHHHEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
PVIDRLSKKGKPIYKFPVARLKEEGYNFSFSGLKTAVRVFREKNPEAKVEDIAASFQEAL
HHHHHHHHCCCCEEECHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VRALVENTEKALKECMPAKLYLAGGVAANSRLREEFLNLGKTYNVPVHFPSLQYCTDNAA
HHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCEECCCEECCCHHEECCCCC
MIAAAGYHRYLSGKYAPLNLNAYPSLMLGEERY
EEEHHHHHHHHCCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA