BacMap

Definition	Carboxydothermus hydrogenoformans Z-2901 chromosome, complete genome.
Accession	NC_007503
Length	2,401,520

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The map label for this gene is crt1 [H]

Identifier: 78043648

GI number: 78043648

Start: 1150993

End: 1151766

Strand: Direct

Name: crt1 [H]

Synonym: CHY_1293

Alternate gene names: 78043648

Gene position: 1150993-1151766 (Clockwise)

Preceding gene: 78044398

Following gene: 78043044

Centisome position: 47.93

GC content: 39.92

Gene sequence:

>774_bases
ATGAGCGTAATTGAAATGGTAAGGGAAGAAGGAATTGCTATACTTACCATCAATAGGGCAAATGTTTTAAATGCTTTAAA
TACCGAAGTGCTTTTAGAATTAAAAAAGGTTTTATCTCAAATCAAAGAAGATACAAGTATTAAGGTTGTTATAATTACCG
GGGCCGGAGAGAAAGCCTTTGTTGCAGGTGCTGATATAAGTGAAATGGTAAAGCAAAGCGTAGATGAAGGGTATAGATAT
TCCCGTTTAGGGCAGGAGGTACTTGCACTTATCGAGAATCTTCCCCAACCGGTAATAGCAGCAGTAAATGGTTATGCTCT
GGGCGGTGGCTGCGAATTAGCTATGGCCTGTGACATGAGGATTGCTTCGGAGAAAGCAAAGTTTGGTCTGCCAGAAATTA
ATTTGGGTATTATTCCAGGGTTTGGAGGCACGAAAAGGCTAACAGAACTGGTAGGTAAAGCTAAAGCAATGGAGTTAATA
TTAACCGGAGAGATGATTGATGCTGCCCAAGCTGAGCGTTTAGGATTAGTTAACCAGGTAGTAAAAGCAGATAAGTTATT
GGAGACAGCAAAGACGCTGGCTCAAAAAATTGCATCTAAAAGTCAAATTGCTGTTCGGGCAGCTAAACTGGCAGTAAATA
AGAGTTTGTACACTGATATTGAAACTGCAAATGCTTGTGAAGCAGGGCTTTTTGGAGTCTGTTTTGCTTCAGAGGATAGA
AAAGAAGGGATGATGGCTTTTTTAGAGAAGCGTCCTGCAAAATTTAAAAATTAG

Upstream 100 bases:

>100_bases
AAAAATTTTTTCTTTTGGCAGTACCTCTTCCGTAAGTTGGGGGCAGGTACTGCCAATACGTGTTTATTCATGAGATATAA
AATTTTGAGGAGGGTTAATG

Downstream 100 bases:

>100_bases
GTAAGAGAATAAGTCTTAATTTGCAAATGTTTTTTTTAACCTGTTCTTATTTACTCAAACATGATTATGTTTTGCTGCAT
TTTAATAAATAAAAGCTATA

Product: 3-hydroxybutyryl-CoA dehydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSVIEMVREEGIAILTINRANVLNALNTEVLLELKKVLSQIKEDTSIKVVIITGAGEKAFVAGADISEMVKQSVDEGYRY
SRLGQEVLALIENLPQPVIAAVNGYALGGGCELAMACDMRIASEKAKFGLPEINLGIIPGFGGTKRLTELVGKAKAMELI
LTGEMIDAAQAERLGLVNQVVKADKLLETAKTLAQKIASKSQIAVRAAKLAVNKSLYTDIETANACEAGLFGVCFASEDR
KEGMMAFLEKRPAKFKN

Sequences:

>Translated_257_residues
MSVIEMVREEGIAILTINRANVLNALNTEVLLELKKVLSQIKEDTSIKVVIITGAGEKAFVAGADISEMVKQSVDEGYRY
SRLGQEVLALIENLPQPVIAAVNGYALGGGCELAMACDMRIASEKAKFGLPEINLGIIPGFGGTKRLTELVGKAKAMELI
LTGEMIDAAQAERLGLVNQVVKADKLLETAKTLAQKIASKSQIAVRAAKLAVNKSLYTDIETANACEAGLFGVCFASEDR
KEGMMAFLEKRPAKFKN
>Mature_256_residues
SVIEMVREEGIAILTINRANVLNALNTEVLLELKKVLSQIKEDTSIKVVIITGAGEKAFVAGADISEMVKQSVDEGYRYS
RLGQEVLALIENLPQPVIAAVNGYALGGGCELAMACDMRIASEKAKFGLPEINLGIIPGFGGTKRLTELVGKAKAMELIL
TGEMIDAAQAERLGLVNQVVKADKLLETAKTLAQKIASKSQIAVRAAKLAVNKSLYTDIETANACEAGLFGVCFASEDRK
EGMMAFLEKRPAKFKN

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=246, Percent_Identity=46.3414634146341, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI4502327, Length=251, Percent_Identity=39.0438247011952, Blast_Score=150, Evalue=9e-37,
Organism=Homo sapiens, GI20127408, Length=175, Percent_Identity=36, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI31542718, Length=243, Percent_Identity=32.9218106995885, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI150378541, Length=255, Percent_Identity=32.9411764705882, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI68989263, Length=188, Percent_Identity=38.2978723404255, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI70995211, Length=216, Percent_Identity=33.7962962962963, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI213417737, Length=241, Percent_Identity=30.2904564315353, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI157694516, Length=241, Percent_Identity=30.2904564315353, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI221136756, Length=253, Percent_Identity=26.8774703557312, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI221136753, Length=253, Percent_Identity=26.8774703557312, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI37594469, Length=200, Percent_Identity=31.5, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI37594471, Length=198, Percent_Identity=31.8181818181818, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI221307494, Length=253, Percent_Identity=26.8774703557312, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI62530384, Length=244, Percent_Identity=29.0983606557377, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI25453481, Length=258, Percent_Identity=28.2945736434109, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI51538573, Length=258, Percent_Identity=28.2945736434109, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI157694520, Length=212, Percent_Identity=28.7735849056604, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI4757968, Length=256, Percent_Identity=27.734375, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI49355787, Length=256, Percent_Identity=27.734375, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI260274832, Length=247, Percent_Identity=26.7206477732794, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI45643119, Length=247, Percent_Identity=26.7206477732794, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI260275230, Length=247, Percent_Identity=26.7206477732794, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI116235487, Length=249, Percent_Identity=25.3012048192771, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4757966, Length=248, Percent_Identity=28.6290322580645, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI51538581, Length=248, Percent_Identity=28.6290322580645, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI261878539, Length=96, Percent_Identity=42.7083333333333, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI295842266, Length=242, Percent_Identity=26.0330578512397, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI1787659, Length=256, Percent_Identity=44.921875, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI221142681, Length=257, Percent_Identity=35.7976653696498, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1788682, Length=210, Percent_Identity=40.4761904761905, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790281, Length=191, Percent_Identity=38.2198952879581, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787660, Length=251, Percent_Identity=35.4581673306773, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1788597, Length=255, Percent_Identity=34.1176470588235, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082183, Length=248, Percent_Identity=29.8387096774194, Blast_Score=113, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17554946, Length=255, Percent_Identity=43.5294117647059, Blast_Score=199, Evalue=9e-52,
Organism=Caenorhabditis elegans, GI25145438, Length=246, Percent_Identity=42.6829268292683, Blast_Score=193, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17540714, Length=224, Percent_Identity=43.3035714285714, Blast_Score=180, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17558304, Length=216, Percent_Identity=34.2592592592593, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17560910, Length=263, Percent_Identity=32.319391634981, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17508953, Length=224, Percent_Identity=36.6071428571429, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25144276, Length=224, Percent_Identity=36.6071428571429, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17508951, Length=224, Percent_Identity=36.6071428571429, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17536985, Length=276, Percent_Identity=28.9855072463768, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17534483, Length=251, Percent_Identity=28.6852589641434, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI25144157, Length=188, Percent_Identity=31.9148936170213, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144160, Length=188, Percent_Identity=31.9148936170213, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17540306, Length=245, Percent_Identity=29.7959183673469, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=237, Percent_Identity=27.4261603375527, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI25141363, Length=204, Percent_Identity=24.5098039215686, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17535521, Length=260, Percent_Identity=25.7692307692308, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=183, Percent_Identity=30.0546448087432, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI20129971, Length=246, Percent_Identity=49.5934959349593, Blast_Score=228, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24653477, Length=246, Percent_Identity=49.5934959349593, Blast_Score=228, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24653139, Length=251, Percent_Identity=39.0438247011952, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI19922422, Length=255, Percent_Identity=27.843137254902, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19920382, Length=222, Percent_Identity=31.5315315315315, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24650670, Length=253, Percent_Identity=28.8537549407115, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI28571730, Length=181, Percent_Identity=34.2541436464088, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571729, Length=181, Percent_Identity=34.2541436464088, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357171, Length=249, Percent_Identity=29.718875502008, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19921000, Length=175, Percent_Identity=36.5714285714286, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24583077, Length=175, Percent_Identity=36.5714285714286, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24583079, Length=175, Percent_Identity=36.5714285714286, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI19921018, Length=183, Percent_Identity=31.6939890710383, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24654903, Length=184, Percent_Identity=28.2608695652174, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24583165, Length=180, Percent_Identity=30, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45550169, Length=137, Percent_Identity=30.6569343065693, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27561; Mature: 27429

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIEMVREEGIAILTINRANVLNALNTEVLLELKKVLSQIKEDTSIKVVIITGAGEKAF
CHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
VAGADISEMVKQSVDEGYRYSRLGQEVLALIENLPQPVIAAVNGYALGGGCELAMACDMR
EECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCEEECCCCEEEHHHCHH
IASEKAKFGLPEINLGIIPGFGGTKRLTELVGKAKAMELILTGEMIDAAQAERLGLVNQV
HHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHH
VKADKLLETAKTLAQKIASKSQIAVRAAKLAVNKSLYTDIETANACEAGLFGVCFASEDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCEEEEECCCCH
KEGMMAFLEKRPAKFKN
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVIEMVREEGIAILTINRANVLNALNTEVLLELKKVLSQIKEDTSIKVVIITGAGEKAF
HHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
VAGADISEMVKQSVDEGYRYSRLGQEVLALIENLPQPVIAAVNGYALGGGCELAMACDMR
EECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCEEECCCCEEEHHHCHH
IASEKAKFGLPEINLGIIPGFGGTKRLTELVGKAKAMELILTGEMIDAAQAERLGLVNQV
HHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHH
VKADKLLETAKTLAQKIASKSQIAVRAAKLAVNKSLYTDIETANACEAGLFGVCFASEDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCEEEEECCCCH
KEGMMAFLEKRPAKFKN
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]