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The map label for this gene is ubiE [C]

Identifier: 78043614

GI number: 78043614

Start: 479998

End: 480576

Strand: Direct

Name: ubiE [C]

Synonym: CHY_0552

Alternate gene names: 78043614

Gene position: 479998-480576 (Clockwise)

Preceding gene: 78042690

Following gene: 78042898

Centisome position: 19.99

GC content: 44.21

Gene sequence:

>579_bases
ATGGGTCATGTTTTTGATCCGCAAAATCGGCATAGGTTAAAAAACGAAAAACGAAAAAAAATCCTGCCCCCCGAGGAGAC
GGTGGCCAAACTGCCGCTAAATCCCGGGGAGGTTATTTTAGACTACGGTGCGGGGATTGGTTATTTTACCGTACCTCTTG
CTAAAAGAACCGGGAGCTCGGGGGTGGTTTATGCCGTTGATATTTCCCCCGAGATTATAAAAGACCTGGAAGAAGAAGTG
TTAAAAGAGGGACTTACAAATGTTAAAACAGCTTTAGTTCCCGGGGATGGGAGTCTACCGGAAGAGTTTCCGGAGTTTGA
TGTAATTTTTTTAGCAACGGTGTTGCACGAGCTTTCGGAAAAAGAAGCGGTTTTATCCGCATTGACCCAAAAACTGAAAA
AACAGGGTAAGCTAATTATCATTGACTGGGAAAAGAAAGAAACCGAATTTGGCCCTCCGGTAGCCCACAGGGTTTCTGTG
GAGGAGGCGGTTTCTTATCTTGAAAAAGCTGGTTTAAAGCTACTGCAGAAGATGAACGTAAGTGCAGCTCACTGGGGTAT
AATAGGGATAAAAGAATAA

Upstream 100 bases:

>100_bases
GCGCTGGCCGGCTCATTCGGTGAAGCCGGAAATGATTATCGAAAAAGAAGAACTGGAAGACGAAATAGCTGAGCTCAAAA
AGGCTATTGCGGAAGAAAAG

Downstream 100 bases:

>100_bases
AAGGAGGAGGTCTTTATGGTTTTAAAGTTTACCGATGCCAATTTTGAAGATGAAGTAATTAATTCCGATATGCCGGTATT
AGTAGATTTTTGGGCGGAGT

Product: hypothetical protein

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: SAM-Dependent Methyltransferase; Methyltransferase; Methyltransferase UbiE/COQ5 Family; Methyltransferase Domain Protein; UbiE/COQ5 Family Methlytransferase; Methylase Involved In Ubiquinone/Menaquinone Biosynthesis; Ubiquinone/Menaquinone Biosynthesis Methyltransferase; RRNA-Methyltransferase; UbiE/COQ5 Methyltransferase

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MGHVFDPQNRHRLKNEKRKKILPPEETVAKLPLNPGEVILDYGAGIGYFTVPLAKRTGSSGVVYAVDISPEIIKDLEEEV
LKEGLTNVKTALVPGDGSLPEEFPEFDVIFLATVLHELSEKEAVLSALTQKLKKQGKLIIIDWEKKETEFGPPVAHRVSV
EEAVSYLEKAGLKLLQKMNVSAAHWGIIGIKE

Sequences:

>Translated_192_residues
MGHVFDPQNRHRLKNEKRKKILPPEETVAKLPLNPGEVILDYGAGIGYFTVPLAKRTGSSGVVYAVDISPEIIKDLEEEV
LKEGLTNVKTALVPGDGSLPEEFPEFDVIFLATVLHELSEKEAVLSALTQKLKKQGKLIIIDWEKKETEFGPPVAHRVSV
EEAVSYLEKAGLKLLQKMNVSAAHWGIIGIKE
>Mature_191_residues
GHVFDPQNRHRLKNEKRKKILPPEETVAKLPLNPGEVILDYGAGIGYFTVPLAKRTGSSGVVYAVDISPEIIKDLEEEVL
KEGLTNVKTALVPGDGSLPEEFPEFDVIFLATVLHELSEKEAVLSALTQKLKKQGKLIIIDWEKKETEFGPPVAHRVSVE
EAVSYLEKAGLKLLQKMNVSAAHWGIIGIKE

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 21231; Mature: 21100

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHVFDPQNRHRLKNEKRKKILPPEETVAKLPLNPGEVILDYGAGIGYFTVPLAKRTGSS
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEECCCCCCEEEEEHHHCCCCC
GVVYAVDISPEIIKDLEEEVLKEGLTNVKTALVPGDGSLPEEFPEFDVIFLATVLHELSE
CEEEEEECCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
KEAVLSALTQKLKKQGKLIIIDWEKKETEFGPPVAHRVSVEEAVSYLEKAGLKLLQKMNV
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCC
SAAHWGIIGIKE
CHHHCCEEEECC
>Mature Secondary Structure 
GHVFDPQNRHRLKNEKRKKILPPEETVAKLPLNPGEVILDYGAGIGYFTVPLAKRTGSS
CCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEECCCCCCEEEEEHHHCCCCC
GVVYAVDISPEIIKDLEEEVLKEGLTNVKTALVPGDGSLPEEFPEFDVIFLATVLHELSE
CEEEEEECCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
KEAVLSALTQKLKKQGKLIIIDWEKKETEFGPPVAHRVSVEEAVSYLEKAGLKLLQKMNV
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCC
SAAHWGIIGIKE
CHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA