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The map label for this gene is yiaY [H]

Identifier: 78043360

GI number: 78043360

Start: 816099

End: 817250

Strand: Direct

Name: yiaY [H]

Synonym: CHY_0925

Alternate gene names: 78043360

Gene position: 816099-817250 (Clockwise)

Preceding gene: 78043182

Following gene: 78044153

Centisome position: 33.98

GC content: 42.27

Gene sequence:

>1152_bases
ATGAAGACGTACCGTTTTTACATGCCGCCGGTTAGCCTAATGGGTATTGGCTGCCTGAAAGAGGCCGGCGAGGAAATTAA
AAAGCTCGGTTTTAAAAAAGCTCTTATTGTAACCGATAAGGTACTGGTTAAGATTGGTCTTGTTAATAAGTTAACCGAAA
TCCTGGACAACGAAGGAATCGAGTACGTTATTTTTGATGAAACTAAACCAAATCCTACGGTTAAAAATGTTGAAGATGGT
CTTAAAATGTTAAAAGAGAACAACTGTGATTTTTTAATTTCCTTTGGTGGAGGTTCGCCTCATGACTGTGCCAAAGGCAT
TGGGCTGGTGGCAACTAATGGTGGCTCCATCAAGGATTATGAAGGGGTAAATAAGTCGGCTAAACCCATGTTACCTCTGG
TGGCGGTAAACACTACTGCTGGTACCGCAAGTGAAATGACGAGATTTTCAATAATAACCGACGAGGATAGACACGTAAAG
ATGGCCATTGTCGACTGGCATGTAACTCCGATAATGGCTGTTAACGATCCCGAATTAATGGTAGAGATGCCAAAAGCTTT
AACTGCCGCAACGGGTATGGATGCCTTAACCCATGCTATTGAAGCTTACGTATCTATTGATGCAACTCCGGTTACCGACG
CGGCAGCTTTAAAGGCAATCGAGCTTATTTTTAAATACCTGAAACGGGCAGTAGAAAATGGAAAGGATATTGAGGCAAGG
GATAAAATGGCTTATGCGGAGTATTTAGCCGGGGTAGCCTTTAACAATGCAGGCTTAGGATATGTACACGCGATGGCCCA
CCAGCTGGGAGGGTTTTACGATCTTCCTCATGGTGTGTGTAATGCTGTATTGCTACCTCATGTGCAGGCCTATAATCTGC
AGGTTGTACCCGAAAGGTTTATTGATATAGCTAAGGCAATGGGAATAAATGTAGAAAACTTAACGGCAAAAGAAGCTGGA
GAAAAGGTACTTGAAGCAATTAAAAATCTTTCGCGGGAAATTGGCATACCATCGGGTCTTAAGGAATTAGGAGTTAAGGA
AGAGGATCTTAAGACTTTAGCCGAAAATGCCCTGAAAGATGCTTGCGGATTTACCAATCCAAAGCAGGCGAGCTTAGATG
ATATTATACGGATATTTAAAGAAGCAATGTAA

Upstream 100 bases:

>100_bases
ATTTTGGGTTATTTTTTGCAAAAACGGGTTAGATTCGGCGTTTTTTGCTTGTTATAATTTTATCAAACTTTAAAAATAAA
ATGAATAGGAGGTTATAAAA

Downstream 100 bases:

>100_bases
TTTTAACTGCATCGATAGACTTTTTGCCGTTTAATATTCGCCAATACTTCGGGTATTGGCGAATTTCTTTGCCTCTGGCA
TTTACCCGTTGAATCCTAAT

Product: putative lactaldehyde reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKTYRFYMPPVSLMGIGCLKEAGEEIKKLGFKKALIVTDKVLVKIGLVNKLTEILDNEGIEYVIFDETKPNPTVKNVEDG
LKMLKENNCDFLISFGGGSPHDCAKGIGLVATNGGSIKDYEGVNKSAKPMLPLVAVNTTAGTASEMTRFSIITDEDRHVK
MAIVDWHVTPIMAVNDPELMVEMPKALTAATGMDALTHAIEAYVSIDATPVTDAAALKAIELIFKYLKRAVENGKDIEAR
DKMAYAEYLAGVAFNNAGLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNLQVVPERFIDIAKAMGINVENLTAKEAG
EKVLEAIKNLSREIGIPSGLKELGVKEEDLKTLAENALKDACGFTNPKQASLDDIIRIFKEAM

Sequences:

>Translated_383_residues
MKTYRFYMPPVSLMGIGCLKEAGEEIKKLGFKKALIVTDKVLVKIGLVNKLTEILDNEGIEYVIFDETKPNPTVKNVEDG
LKMLKENNCDFLISFGGGSPHDCAKGIGLVATNGGSIKDYEGVNKSAKPMLPLVAVNTTAGTASEMTRFSIITDEDRHVK
MAIVDWHVTPIMAVNDPELMVEMPKALTAATGMDALTHAIEAYVSIDATPVTDAAALKAIELIFKYLKRAVENGKDIEAR
DKMAYAEYLAGVAFNNAGLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNLQVVPERFIDIAKAMGINVENLTAKEAG
EKVLEAIKNLSREIGIPSGLKELGVKEEDLKTLAENALKDACGFTNPKQASLDDIIRIFKEAM
>Mature_383_residues
MKTYRFYMPPVSLMGIGCLKEAGEEIKKLGFKKALIVTDKVLVKIGLVNKLTEILDNEGIEYVIFDETKPNPTVKNVEDG
LKMLKENNCDFLISFGGGSPHDCAKGIGLVATNGGSIKDYEGVNKSAKPMLPLVAVNTTAGTASEMTRFSIITDEDRHVK
MAIVDWHVTPIMAVNDPELMVEMPKALTAATGMDALTHAIEAYVSIDATPVTDAAALKAIELIFKYLKRAVENGKDIEAR
DKMAYAEYLAGVAFNNAGLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNLQVVPERFIDIAKAMGINVENLTAKEAG
EKVLEAIKNLSREIGIPSGLKELGVKEEDLKTLAENALKDACGFTNPKQASLDDIIRIFKEAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=408, Percent_Identity=27.9411764705882, Blast_Score=160, Evalue=1e-39,
Organism=Escherichia coli, GI48994951, Length=383, Percent_Identity=61.3577023498694, Blast_Score=500, Evalue=1e-143,
Organism=Escherichia coli, GI1789163, Length=385, Percent_Identity=43.8961038961039, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI87082107, Length=377, Percent_Identity=37.9310344827586, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI1787493, Length=398, Percent_Identity=33.9195979899498, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1789386, Length=365, Percent_Identity=23.8356164383562, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17537053, Length=423, Percent_Identity=28.1323877068558, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6321181, Length=379, Percent_Identity=55.6728232189974, Blast_Score=421, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24657991, Length=421, Percent_Identity=27.3159144893112, Blast_Score=155, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 41601; Mature: 41601

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYRFYMPPVSLMGIGCLKEAGEEIKKLGFKKALIVTDKVLVKIGLVNKLTEILDNEGI
CCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EYVIFDETKPNPTVKNVEDGLKMLKENNCDFLISFGGGSPHDCAKGIGLVATNGGSIKDY
EEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCEEEEECCCCCCCC
EGVNKSAKPMLPLVAVNTTAGTASEMTRFSIITDEDRHVKMAIVDWHVTPIMAVNDPELM
CCCCCCCCCCCEEEEEECCCCCHHHHHEEEEEECCCCEEEEEEEEEECCEEEEECCHHHH
VEMPKALTAATGMDALTHAIEAYVSIDATPVTDAAALKAIELIFKYLKRAVENGKDIEAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DKMAYAEYLAGVAFNNAGLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNLQVVPERF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCEEECHHHH
IDIAKAMGINVENLTAKEAGEKVLEAIKNLSREIGIPSGLKELGVKEEDLKTLAENALKD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHH
ACGFTNPKQASLDDIIRIFKEAM
HHCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKTYRFYMPPVSLMGIGCLKEAGEEIKKLGFKKALIVTDKVLVKIGLVNKLTEILDNEGI
CCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EYVIFDETKPNPTVKNVEDGLKMLKENNCDFLISFGGGSPHDCAKGIGLVATNGGSIKDY
EEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCEEEEECCCCCCCC
EGVNKSAKPMLPLVAVNTTAGTASEMTRFSIITDEDRHVKMAIVDWHVTPIMAVNDPELM
CCCCCCCCCCCEEEEEECCCCCHHHHHEEEEEECCCCEEEEEEEEEECCEEEEECCHHHH
VEMPKALTAATGMDALTHAIEAYVSIDATPVTDAAALKAIELIFKYLKRAVENGKDIEAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DKMAYAEYLAGVAFNNAGLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNLQVVPERF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCEEECHHHH
IDIAKAMGINVENLTAKEAGEKVLEAIKNLSREIGIPSGLKELGVKEEDLKTLAENALKD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHH
ACGFTNPKQASLDDIIRIFKEAM
HHCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]