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The map label for this gene is iscR [H]

Identifier: 78043306

GI number: 78043306

Start: 343401

End: 343829

Strand: Direct

Name: iscR [H]

Synonym: CHY_0401

Alternate gene names: 78043306

Gene position: 343401-343829 (Clockwise)

Preceding gene: 78044257

Following gene: 78044921

Centisome position: 14.3

GC content: 43.12

Gene sequence:

>429_bases
ATGCAGCTTACAAAACAGGGGGAATATGCTTTAATTGCCTTGATGGATCTGGCAAAACTGCCTAAAGGCCAGGTAGTACC
GGTAAAAACCCTGGCGGAAAGGCTGATGTTGCCGGAGGCTTTTTTAGCAAAAATCGTGCAGTCTTTGGTTAAAGCAGGCC
TTGTCTATACAGTAAAAGGACCGCAGGGGGGTGTTGCCCTCCTGAAAGATCCGGAAAAGATTACTGTTTTGGAAGTAGTT
GAAGCGGTGGAGGGACCGATAGTTTTAAGTCAGTGTATTAACCATCCGGATATTTGTGAGAAAGTGGAAATTTGCCCGTT
ACATAAGATTTGGCATAAAGTTCAGCAAAAATTAATTGAGGAGTTTTCCTCTCATAATCTTTTAACGCTTTCCAAAGAAG
GCCAGTTAAGTGGCTTTTTAGCGGAGTAG

Upstream 100 bases:

>100_bases
GAAAATACGACAATTTTCGACAAATTTTATTTATATTGAAAAAATATAAAATATATTGTAAAATACCTTAGAAAGCTTGA
TTTTTTCAGGGGGAAAATTC

Downstream 100 bases:

>100_bases
CTTATGAATCCCTTTGATGACCGTTCCAAGCTTTCTTTATATGGAATTATTTTTTTACTTTTAGCCTTGGTTTGCTATTT
ATGGTGGACCGGGCCGGAAT

Product: rrf2 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MQLTKQGEYALIALMDLAKLPKGQVVPVKTLAERLMLPEAFLAKIVQSLVKAGLVYTVKGPQGGVALLKDPEKITVLEVV
EAVEGPIVLSQCINHPDICEKVEICPLHKIWHKVQQKLIEEFSSHNLLTLSKEGQLSGFLAE

Sequences:

>Translated_142_residues
MQLTKQGEYALIALMDLAKLPKGQVVPVKTLAERLMLPEAFLAKIVQSLVKAGLVYTVKGPQGGVALLKDPEKITVLEVV
EAVEGPIVLSQCINHPDICEKVEICPLHKIWHKVQQKLIEEFSSHNLLTLSKEGQLSGFLAE
>Mature_142_residues
MQLTKQGEYALIALMDLAKLPKGQVVPVKTLAERLMLPEAFLAKIVQSLVKAGLVYTVKGPQGGVALLKDPEKITVLEVV
EAVEGPIVLSQCINHPDICEKVEICPLHKIWHKVQQKLIEEFSSHNLLTLSKEGQLSGFLAE

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790621, Length=135, Percent_Identity=30.3703703703704, Blast_Score=69, Evalue=9e-14,
Organism=Escherichia coli, GI1788880, Length=118, Percent_Identity=33.0508474576271, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15604; Mature: 15604

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTKQGEYALIALMDLAKLPKGQVVPVKTLAERLMLPEAFLAKIVQSLVKAGLVYTVKG
CCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEC
PQGGVALLKDPEKITVLEVVEAVEGPIVLSQCINHPDICEKVEICPLHKIWHKVQQKLIE
CCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHH
EFSSHNLLTLSKEGQLSGFLAE
HHCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MQLTKQGEYALIALMDLAKLPKGQVVPVKTLAERLMLPEAFLAKIVQSLVKAGLVYTVKG
CCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEC
PQGGVALLKDPEKITVLEVVEAVEGPIVLSQCINHPDICEKVEICPLHKIWHKVQQKLIE
CCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHH
EFSSHNLLTLSKEGQLSGFLAE
HHCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA