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The map label for this gene is tldD [H]

Identifier: 78043221

GI number: 78043221

Start: 554833

End: 556221

Strand: Direct

Name: tldD [H]

Synonym: CHY_0642

Alternate gene names: 78043221

Gene position: 554833-556221 (Clockwise)

Preceding gene: 78044661

Following gene: 78044390

Centisome position: 23.1

GC content: 50.18

Gene sequence:

>1389_bases
ATGGATAACTTCACAATAAACGAAGTGTTACGGGAAGCGGCCCGCCGGGGAGCGCCCTTTGCGGAAATATATTTTGAAGA
AAAAAATAACTTTGGCCTTGTTTTAGAAGACGGAAAAATTGAAAAAGTAACTCAGGGTTACGAAGCTGGTGCCGGTATCC
GGGTGATAGATGATAACGGAAGAACAACTTACGCCTATACCAATGATTTATCTTTGGAAGCTCTTTTAAAGGCCGTTCGG
GTAGCTACTCTGGGTTTAAATGGGTTAAAGGACAGTGTGAGCCTGGAAAATCCCGAAGTCACCTCCGGTAACGTGCAGAT
TAAGCCGGGAGAAGTGGCAGCGGAAGAAAAACTAAACCTTTTAAAAGTTGCCGATGAAGAGATCAGAAGACTCGGTCCTG
AAATTCGCCAGGTGCAGGCGAGTTACGGGGAGTTGGAAGCCAAAGTAGTTATTGCCAATACCGAAGGCACTTATGTTGAG
ATGAACAAAACCCGGGTGCGGTTTGCGGTCCAGGCGGTAGCGGAAAAAGATGGGGTTATTCAGACCGGCTACGATGCCAT
AGGTACTACCAAAGGTTTTGAGACTTTTAAGGAGCAGCAGGTGGATGTTGCGGCCCGGGCAGCGGGAGAACGGGCCATTA
AAATGCTTTCGGCCGAGCCCGCCCCTTCGGGGGAAATGCCGGTGGTGATGGCCGGTGAAGCCGGCGGCACCATGATTCAC
GAAGCTTCGGGGCACGGCCTGGAGGCGGACATAGTCCAAAAGCGAATGAGCGTTTATGCCGGAAAAAAGGGTCAGAAGGT
GGCCTCGCCATTGATTACTGTGGTGGATGATGGCACAATCCCCGGAAAATACGGGACCGTACCGTACGATGATGAAGGAA
ACAAAACGAAGAAAAATGTTCTCATTGACCGGGGGATTTTAACCGGTTATATGTATGACCGGCTAACTGCTAAAAAAGAT
AACGTTGAGCCTACCGGAAATGGAAGAAGGGAGTCGTATCAGCATAAACCGATTCCCCGGATGACTAACACGTATATAGC
TCCCGGTGAAGACGACCCGGAAAAGATTATTCGGGAGGTAAAAGAGGGTTTACTGGTTAAAAAAATGGGTGGTGGACAGG
TGGACACCAATACCGGCGATTTTGTTTTTGAGGTATCCGAAGGGTACCTGATTGAAGACGGCCAGGTTACCGTTCCGGTA
AGAGGAGCTACTTTAACCGGCAACGGCCCCAAAGTTTTAAACAATGTGCTGGCCGTAGGTAAAGACCTGGGCTGGTCTAT
CGGTACCTGCGGTAAAGACGGCCAGGGCGTTCCCGTTTCCGACGCCCAGCCTACTCTCTTAATTGGTAACCTGGTGGTAG
GTGGCACCGGCCGCATCCGCCGCAAATAG

Upstream 100 bases:

>100_bases
CGCCTTACTGCGGGGTTTTTATTTTATTTCTTGGAAAAAAAGGATATAATGTTAGTTAAGGAGAATTTCTCAGCATTAGA
GATAATGAGGGGGAAAGCCA

Downstream 100 bases:

>100_bases
CAAAAAGAGGTATAATTTTAGGGACTGTCCCCAAATTTATACTTGAGGAGGGTGTAGTGTATGCCGGCGTATGATTTTCG
CTGTAACGATTGTGGCGAAC

Product: tldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MDNFTINEVLREAARRGAPFAEIYFEEKNNFGLVLEDGKIEKVTQGYEAGAGIRVIDDNGRTTYAYTNDLSLEALLKAVR
VATLGLNGLKDSVSLENPEVTSGNVQIKPGEVAAEEKLNLLKVADEEIRRLGPEIRQVQASYGELEAKVVIANTEGTYVE
MNKTRVRFAVQAVAEKDGVIQTGYDAIGTTKGFETFKEQQVDVAARAAGERAIKMLSAEPAPSGEMPVVMAGEAGGTMIH
EASGHGLEADIVQKRMSVYAGKKGQKVASPLITVVDDGTIPGKYGTVPYDDEGNKTKKNVLIDRGILTGYMYDRLTAKKD
NVEPTGNGRRESYQHKPIPRMTNTYIAPGEDDPEKIIREVKEGLLVKKMGGGQVDTNTGDFVFEVSEGYLIEDGQVTVPV
RGATLTGNGPKVLNNVLAVGKDLGWSIGTCGKDGQGVPVSDAQPTLLIGNLVVGGTGRIRRK

Sequences:

>Translated_462_residues
MDNFTINEVLREAARRGAPFAEIYFEEKNNFGLVLEDGKIEKVTQGYEAGAGIRVIDDNGRTTYAYTNDLSLEALLKAVR
VATLGLNGLKDSVSLENPEVTSGNVQIKPGEVAAEEKLNLLKVADEEIRRLGPEIRQVQASYGELEAKVVIANTEGTYVE
MNKTRVRFAVQAVAEKDGVIQTGYDAIGTTKGFETFKEQQVDVAARAAGERAIKMLSAEPAPSGEMPVVMAGEAGGTMIH
EASGHGLEADIVQKRMSVYAGKKGQKVASPLITVVDDGTIPGKYGTVPYDDEGNKTKKNVLIDRGILTGYMYDRLTAKKD
NVEPTGNGRRESYQHKPIPRMTNTYIAPGEDDPEKIIREVKEGLLVKKMGGGQVDTNTGDFVFEVSEGYLIEDGQVTVPV
RGATLTGNGPKVLNNVLAVGKDLGWSIGTCGKDGQGVPVSDAQPTLLIGNLVVGGTGRIRRK
>Mature_462_residues
MDNFTINEVLREAARRGAPFAEIYFEEKNNFGLVLEDGKIEKVTQGYEAGAGIRVIDDNGRTTYAYTNDLSLEALLKAVR
VATLGLNGLKDSVSLENPEVTSGNVQIKPGEVAAEEKLNLLKVADEEIRRLGPEIRQVQASYGELEAKVVIANTEGTYVE
MNKTRVRFAVQAVAEKDGVIQTGYDAIGTTKGFETFKEQQVDVAARAAGERAIKMLSAEPAPSGEMPVVMAGEAGGTMIH
EASGHGLEADIVQKRMSVYAGKKGQKVASPLITVVDDGTIPGKYGTVPYDDEGNKTKKNVLIDRGILTGYMYDRLTAKKD
NVEPTGNGRRESYQHKPIPRMTNTYIAPGEDDPEKIIREVKEGLLVKKMGGGQVDTNTGDFVFEVSEGYLIEDGQVTVPV
RGATLTGNGPKVLNNVLAVGKDLGWSIGTCGKDGQGVPVSDAQPTLLIGNLVVGGTGRIRRK

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=458, Percent_Identity=40.3930131004367, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI1790682, Length=417, Percent_Identity=21.5827338129496, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49690; Mature: 49690

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNFTINEVLREAARRGAPFAEIYFEEKNNFGLVLEDGKIEKVTQGYEAGAGIRVIDDNG
CCCCCHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCCCHHHHCCCCCCCCEEEEECCC
RTTYAYTNDLSLEALLKAVRVATLGLNGLKDSVSLENPEVTSGNVQIKPGEVAAEEKLNL
CEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHH
LKVADEEIRRLGPEIRQVQASYGELEAKVVIANTEGTYVEMNKTRVRFAVQAVAEKDGVI
HHHHHHHHHHHCHHHHHHHHHCCCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHCCCCE
QTGYDAIGTTKGFETFKEQQVDVAARAAGERAIKMLSAEPAPSGEMPVVMAGEAGGTMIH
EECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEE
EASGHGLEADIVQKRMSVYAGKKGQKVASPLITVVDDGTIPGKYGTVPYDDEGNKTKKNV
ECCCCCCHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHE
LIDRGILTGYMYDRLTAKKDNVEPTGNGRRESYQHKPIPRMTNTYIAPGEDDPEKIIREV
EEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHH
KEGLLVKKMGGGQVDTNTGDFVFEVSEGYLIEDGQVTVPVRGATLTGNGPKVLNNVLAVG
HCCEEEEECCCCEEECCCCCEEEEECCCEEEECCEEEEEEECEEEECCCHHHHHHHHHHH
KDLGWSIGTCGKDGQGVPVSDAQPTLLIGNLVVGGTGRIRRK
HCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MDNFTINEVLREAARRGAPFAEIYFEEKNNFGLVLEDGKIEKVTQGYEAGAGIRVIDDNG
CCCCCHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCCCHHHHCCCCCCCCEEEEECCC
RTTYAYTNDLSLEALLKAVRVATLGLNGLKDSVSLENPEVTSGNVQIKPGEVAAEEKLNL
CEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHH
LKVADEEIRRLGPEIRQVQASYGELEAKVVIANTEGTYVEMNKTRVRFAVQAVAEKDGVI
HHHHHHHHHHHCHHHHHHHHHCCCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHCCCCE
QTGYDAIGTTKGFETFKEQQVDVAARAAGERAIKMLSAEPAPSGEMPVVMAGEAGGTMIH
EECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEE
EASGHGLEADIVQKRMSVYAGKKGQKVASPLITVVDDGTIPGKYGTVPYDDEGNKTKKNV
ECCCCCCHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHE
LIDRGILTGYMYDRLTAKKDNVEPTGNGRRESYQHKPIPRMTNTYIAPGEDDPEKIIREV
EEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHH
KEGLLVKKMGGGQVDTNTGDFVFEVSEGYLIEDGQVTVPVRGATLTGNGPKVLNNVLAVG
HCCEEEEECCCCEEECCCCCEEEEECCCEEEECCEEEEEEECEEEECCCHHHHHHHHHHH
KDLGWSIGTCGKDGQGVPVSDAQPTLLIGNLVVGGTGRIRRK
HCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]