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The map label for this gene is fadR [H]

Identifier: 78043066

GI number: 78043066

Start: 444428

End: 444994

Strand: Direct

Name: fadR [H]

Synonym: CHY_0512

Alternate gene names: 78043066

Gene position: 444428-444994 (Clockwise)

Preceding gene: 78044348

Following gene: 78043608

Centisome position: 18.51

GC content: 35.8

Gene sequence:

>567_bases
ATGAATCCAAAGATTCGGGCGATTTTAAAAGCTGCGGCTAAAGTGATGGCCCAAAAGGGCTTTGAAAAAGCTACCATGGA
TGAAATTGCTAAAATTAGTAAGGTAGCCAAGGGGACTTTATATTACTATTTCAAAAGTAAAGAGGAACTTTTTTTAAAGC
TTACCCTTTCTATTCTTGAAGAATTAGAGGAAAGAACTAAAAAGGTTTTAGAGTTAAAAGTTTCGGCGGCGGAGAAACTT
AGAGCTTTAATAAAGGTCCAGGTGGAATTTTTCTTAGAGTTTCACGAGGAGGTAGTATTAGTTTTAGGGGATTTCTTTGG
AAGTACCCTTCCCCGGGAAAGTTTTCGGGTAAAGATTAATGATTATTACCGGCTTATAAACCAACTAATAGCGGAAGGGA
TAAAAGCCAACGAATTTCGGGAAGTTAACCTGGAAATTTTTGTTCCGGCTTTTTTTGGAATGACTTCCTTTGCTACTATT
CGCGGTATTTTAAGAGAGAAAGGGTTTTTAAAAGAGCAGCTTATCAATAATTTAACGGAGATAGTTTTAAACGGTTTAAA
AAAATAA

Upstream 100 bases:

>100_bases
ATTGCCTTAATACTAAATTATTTTGTCACGCCAAGGCATGTAAGGCTTTCCGATTTATCGCCTAACGAAGGTAACGTAAT
TTAGCTGTTTGGAGGATAAG

Downstream 100 bases:

>100_bases
CCGGGTTATCCCGGTTATTTTTTTGTAAAGGTTTTGAGAAAAAAGAGAAAAATTTTTGCACCTTGTATACATTTTGTTAT
TTTATTGACAAAAGCGGTTG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MNPKIRAILKAAAKVMAQKGFEKATMDEIAKISKVAKGTLYYYFKSKEELFLKLTLSILEELEERTKKVLELKVSAAEKL
RALIKVQVEFFLEFHEEVVLVLGDFFGSTLPRESFRVKINDYYRLINQLIAEGIKANEFREVNLEIFVPAFFGMTSFATI
RGILREKGFLKEQLINNLTEIVLNGLKK

Sequences:

>Translated_188_residues
MNPKIRAILKAAAKVMAQKGFEKATMDEIAKISKVAKGTLYYYFKSKEELFLKLTLSILEELEERTKKVLELKVSAAEKL
RALIKVQVEFFLEFHEEVVLVLGDFFGSTLPRESFRVKINDYYRLINQLIAEGIKANEFREVNLEIFVPAFFGMTSFATI
RGILREKGFLKEQLINNLTEIVLNGLKK
>Mature_188_residues
MNPKIRAILKAAAKVMAQKGFEKATMDEIAKISKVAKGTLYYYFKSKEELFLKLTLSILEELEERTKKVLELKVSAAEKL
RALIKVQVEFFLEFHEEVVLVLGDFFGSTLPRESFRVKINDYYRLINQLIAEGIKANEFREVNLEIFVPAFFGMTSFATI
RGILREKGFLKEQLINNLTEIVLNGLKK

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21645; Mature: 21645

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPKIRAILKAAAKVMAQKGFEKATMDEIAKISKVAKGTLYYYFKSKEELFLKLTLSILE
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHH
ELEERTKKVLELKVSAAEKLRALIKVQVEFFLEFHEEVVLVLGDFFGSTLPRESFRVKIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEHH
DYYRLINQLIAEGIKANEFREVNLEIFVPAFFGMTSFATIRGILREKGFLKEQLINNLTE
HHHHHHHHHHHCCCCCCCCEECHHEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IVLNGLKK
HHHHHCCC
>Mature Secondary Structure
MNPKIRAILKAAAKVMAQKGFEKATMDEIAKISKVAKGTLYYYFKSKEELFLKLTLSILE
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHH
ELEERTKKVLELKVSAAEKLRALIKVQVEFFLEFHEEVVLVLGDFFGSTLPRESFRVKIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEHH
DYYRLINQLIAEGIKANEFREVNLEIFVPAFFGMTSFATIRGILREKGFLKEQLINNLTE
HHHHHHHHHHHCCCCCCCCEECHHEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IVLNGLKK
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]