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The map label for this gene is cobB1 [H]

Identifier: 78043061

GI number: 78043061

Start: 678134

End: 679468

Strand: Direct

Name: cobB1 [H]

Synonym: CHY_0771

Alternate gene names: 78043061

Gene position: 678134-679468 (Clockwise)

Preceding gene: 78043696

Following gene: 78044196

Centisome position: 28.24

GC content: 42.32

Gene sequence:

>1335_bases
ATGAAAGGGTTTATTATAAGTGGTACTACTACAGGAGCTGGCAAAAGTACCTTAACCGTTGGTATCTTAGCAGCTTTAAA
ACACTTGGGCTTAAAGGTGCAGGCCTTTAAGGCTGGGCCTGATTACCTGGATCCTACCTACCACCGTTTAGCGCTTGCTA
AACCTACCTATAACCTCGATGAGATCCTGACTTCTCCGGGATTGGTGCGCCGTCTTTTTTACGAAAAAGCTAAAGCAGCG
GACGTGGCGGTAGTGGAGGGGGTAATGGGCTTATTTGATGGCCGGGACGAAAAGTTTACCGGAAGTACCTATCGCTTAGC
CAGGTTTTTAAATCTTCCGGTAATTTTAGTGGTCGACGCCCAGAATCTTGGTACCACCGTAGCAGCTCAAGTTTACGGTT
ATCTTAAATTTAAAAAAGATATCAAAATTGCCGGGATTATTTTAAACAAAGTTTCGGGGAAAAACCATGCGGAACACCTC
TTATCTGCCTTGAAACCGTTAGGGGTTAAGGTTTTTGGGGTGTTTTACCAAAACGAACTTCCCAGACTTAAATCCAGGCA
TTTAGGTCTTATCCCGGCCACCGAAGAGCAGAATATCCTGGAAATTATTAAAGAAATAAAAGATAAAGTGCTGGCAAAAA
TTAATTTTGCTGACTTGCTGGCAACTTTACCGGAGTTAACTGTTCCAAAAAAGCTTCCGGCAATTAAATACCCCGATTTA
AAAGGAAAGCGCGTAGCTTACGCCTTTGATAAAGCTTTTAATTTTTATTACCAGGAGGCAATTGAGTATTTGAGAAGATC
TAACGCCGAAGTCTTTGCGGTAAGTCCCTTAAACGATTCCGATTTTCCTCCCGTAGACTTACTTTTTTTGGGGGGTGGTT
ATCCCGAGCTTTTTGCCAGGGACTTATTTTTAAACCAAAAATTTATCCAGAATTTAAAAAAGAAAATCCAGGGTGGTCTT
AGAGTTTATGCGGAATGCGGCGGTTTTATTTATTTAACTTCCGGCGTTAAGGTTAAGGAGCAAACTTATCCTTTGACCGG
TATATTACCCGGGGAAATGGAATTAACCGATAAACTTCAGGGCCTTGGTTATTATCGGGGAAAGCCGGTTGGAGGCTACC
TCGGGAAAAATTTTCAAAAGGAAATCTGGGGGCATAAATTTCATTACTCCACTTATACAGGGCCGCAGGACAATCCTGCG
TATCTCTTGCAGAAAAACGGACGGGAAGCCTTTGATGGGGTGGCGAGAGATAATATTTTTGCCTCGTTTTTACATCTTAA
TTTCTACGGTAAGGCCGATTTAGTAAAGACCCTTGTAGGTGGAAGAAAAGGATGA

Upstream 100 bases:

>100_bases
TAACTCCGGAGGTAATAGATAAAGCTTTAAAGCTTTTCTGGTTTACAGTATTTTTAATGGTTTTGCTTTTTGGCGGTTTC
TCTACGGTAGGAGGGGTATG

Downstream 100 bases:

>100_bases
AAATAAAAGCGTATGTTTGCGGTACGGCGGGAGAACTGGTTCAGGGAAGTATTGGAGGAAAAGATTTTTTATTAACTGCC
CCGGTTAACATAGGGAATAT

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKGFIISGTTTGAGKSTLTVGILAALKHLGLKVQAFKAGPDYLDPTYHRLALAKPTYNLDEILTSPGLVRRLFYEKAKAA
DVAVVEGVMGLFDGRDEKFTGSTYRLARFLNLPVILVVDAQNLGTTVAAQVYGYLKFKKDIKIAGIILNKVSGKNHAEHL
LSALKPLGVKVFGVFYQNELPRLKSRHLGLIPATEEQNILEIIKEIKDKVLAKINFADLLATLPELTVPKKLPAIKYPDL
KGKRVAYAFDKAFNFYYQEAIEYLRRSNAEVFAVSPLNDSDFPPVDLLFLGGGYPELFARDLFLNQKFIQNLKKKIQGGL
RVYAECGGFIYLTSGVKVKEQTYPLTGILPGEMELTDKLQGLGYYRGKPVGGYLGKNFQKEIWGHKFHYSTYTGPQDNPA
YLLQKNGREAFDGVARDNIFASFLHLNFYGKADLVKTLVGGRKG

Sequences:

>Translated_444_residues
MKGFIISGTTTGAGKSTLTVGILAALKHLGLKVQAFKAGPDYLDPTYHRLALAKPTYNLDEILTSPGLVRRLFYEKAKAA
DVAVVEGVMGLFDGRDEKFTGSTYRLARFLNLPVILVVDAQNLGTTVAAQVYGYLKFKKDIKIAGIILNKVSGKNHAEHL
LSALKPLGVKVFGVFYQNELPRLKSRHLGLIPATEEQNILEIIKEIKDKVLAKINFADLLATLPELTVPKKLPAIKYPDL
KGKRVAYAFDKAFNFYYQEAIEYLRRSNAEVFAVSPLNDSDFPPVDLLFLGGGYPELFARDLFLNQKFIQNLKKKIQGGL
RVYAECGGFIYLTSGVKVKEQTYPLTGILPGEMELTDKLQGLGYYRGKPVGGYLGKNFQKEIWGHKFHYSTYTGPQDNPA
YLLQKNGREAFDGVARDNIFASFLHLNFYGKADLVKTLVGGRKG
>Mature_444_residues
MKGFIISGTTTGAGKSTLTVGILAALKHLGLKVQAFKAGPDYLDPTYHRLALAKPTYNLDEILTSPGLVRRLFYEKAKAA
DVAVVEGVMGLFDGRDEKFTGSTYRLARFLNLPVILVVDAQNLGTTVAAQVYGYLKFKKDIKIAGIILNKVSGKNHAEHL
LSALKPLGVKVFGVFYQNELPRLKSRHLGLIPATEEQNILEIIKEIKDKVLAKINFADLLATLPELTVPKKLPAIKYPDL
KGKRVAYAFDKAFNFYYQEAIEYLRRSNAEVFAVSPLNDSDFPPVDLLFLGGGYPELFARDLFLNQKFIQNLKKKIQGGL
RVYAECGGFIYLTSGVKVKEQTYPLTGILPGEMELTDKLQGLGYYRGKPVGGYLGKNFQKEIWGHKFHYSTYTGPQDNPA
YLLQKNGREAFDGVARDNIFASFLHLNFYGKADLVKTLVGGRKG

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 49303; Mature: 49303

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGFIISGTTTGAGKSTLTVGILAALKHLGLKVQAFKAGPDYLDPTYHRLALAKPTYNLD
CCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHEEECCCCCCHH
EILTSPGLVRRLFYEKAKAADVAVVEGVMGLFDGRDEKFTGSTYRLARFLNLPVILVVDA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEEC
QNLGTTVAAQVYGYLKFKKDIKIAGIILNKVSGKNHAEHLLSALKPLGVKVFGVFYQNEL
CCCCHHHHHHHHHHHEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEHHCCC
PRLKSRHLGLIPATEEQNILEIIKEIKDKVLAKINFADLLATLPELTVPKKLPAIKYPDL
CHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCC
KGKRVAYAFDKAFNFYYQEAIEYLRRSNAEVFAVSPLNDSDFPPVDLLFLGGGYPELFAR
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHH
DLFLNQKFIQNLKKKIQGGLRVYAECGGFIYLTSGVKVKEQTYPLTGILPGEMELTDKLQ
HHHHCHHHHHHHHHHHHCCEEEEEECCCEEEEECCEEEECCCCCEEEECCCCHHHHHHHH
GLGYYRGKPVGGYLGKNFQKEIWGHKFHYSTYTGPQDNPAYLLQKNGREAFDGVARDNIF
CCCCCCCCCCCCHHCCCHHHHHCCCEEEECCCCCCCCCCEEEEECCCCHHHHCHHHHHHH
ASFLHLNFYGKADLVKTLVGGRKG
HHHHEEEECCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKGFIISGTTTGAGKSTLTVGILAALKHLGLKVQAFKAGPDYLDPTYHRLALAKPTYNLD
CCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHEEECCCCCCHH
EILTSPGLVRRLFYEKAKAADVAVVEGVMGLFDGRDEKFTGSTYRLARFLNLPVILVVDA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEEC
QNLGTTVAAQVYGYLKFKKDIKIAGIILNKVSGKNHAEHLLSALKPLGVKVFGVFYQNEL
CCCCHHHHHHHHHHHEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEHHCCC
PRLKSRHLGLIPATEEQNILEIIKEIKDKVLAKINFADLLATLPELTVPKKLPAIKYPDL
CHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCC
KGKRVAYAFDKAFNFYYQEAIEYLRRSNAEVFAVSPLNDSDFPPVDLLFLGGGYPELFAR
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHH
DLFLNQKFIQNLKKKIQGGLRVYAECGGFIYLTSGVKVKEQTYPLTGILPGEMELTDKLQ
HHHHCHHHHHHHHHHHHCCEEEEEECCCEEEEECCEEEECCCCCEEEECCCCHHHHHHHH
GLGYYRGKPVGGYLGKNFQKEIWGHKFHYSTYTGPQDNPAYLLQKNGREAFDGVARDNIF
CCCCCCCCCCCCHHCCCHHHHHCCCEEEECCCCCCCCCCEEEEECCCCHHHHCHHHHHHH
ASFLHLNFYGKADLVKTLVGGRKG
HHHHEEEECCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA