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The map label for this gene is fba [H]

Identifier: 78043057

GI number: 78043057

Start: 111121

End: 111975

Strand: Direct

Name: fba [H]

Synonym: CHY_0128

Alternate gene names: 78043057

Gene position: 111121-111975 (Clockwise)

Preceding gene: 78044361

Following gene: 78043547

Centisome position: 4.63

GC content: 48.77

Gene sequence:

>855_bases
TTGGCTTTAGTTACGGTTGCGGAACTTTTAACCAAAGCTTACCGGGAAGGGTATGCGGTTGGTGCTTTTAACTGCAACAA
TATGGAAATTGTGCAAGCGATCGTAGCTGCTGCGGAAGCGGAAAACAGCCCTGTTATTATTCAGGCCAGTCAGGGAGCTA
TAAAATATGCGGGTATTGATTATATTGCCGCTTTAAGCCATCAGGCGGCCAAAAATGCCAAAGTACCGGTGGCCCTTCAT
TTAGACCATGGAACCAGTTTAGAACAGGTTATGGCCTGCATCCGGCACGGGTTTACTTCGGTGATGATTGACGGCTCCAA
GTATCCTTTTGCGGAAAACGTGGCCATTACCAAGAAAGTAGTGGAGCTGGCCCATGCGGTAGGAGTTTCGGTAGAGGCGG
AGCTTGGTAAAATTGGCGGGACCGAGGACGATATTTCGGTGGACGAGCGGGACGCTTTCTTTACCGACCCGGAGGAAGCC
CGGGAGTTTGTTGCGCAGACTGGAGTGGATTCTTTGGCGGTAGCTATTGGTACCGCCCATGGCCGCTATAAGGGAGTGCC
AAAACTTGATTTTGAAAGATTGGCAAAAATCCGGGAACTTGTACATATTCCTTTGGTGCTTCACGGTTCGTCCGGTGTCC
CCGATGAGGATATCAAAAAAGCCATTTCCCTGGGTGTGGCCAAAGTAAATATCGATACCAACATCCGGGAGGCGTTTGTG
GGAAAGATGCGGGAAGTTTTAGAGAAAAATCCCGATGAGATTGACCCGCGGAAAATCTTAGGTCCGGCAAGAGAAGCAGC
TATTGAAATTATCCGGGAGAAAATCAGGGTATTTGGTTCTTCCAATAAAGCCTAA

Upstream 100 bases:

>100_bases
TTTGGGCAACTCAGGAAGAAGATGTGCTAAAATTAGGACAGAAGGCTATACTATTAACAACGGTTCCAAAAAAAGAAAAA
TAATTAAAGGGGGAGATATC

Downstream 100 bases:

>100_bases
GAGGTGTTGTTATGGAAATTTTCTTAGACACCGCCAATATTGAGGAGATAAAAAAGGGAGCAAGTCTGGGAATTATCTCC
GGAGTTACTACCAACCCTTC

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MALVTVAELLTKAYREGYAVGAFNCNNMEIVQAIVAAAEAENSPVIIQASQGAIKYAGIDYIAALSHQAAKNAKVPVALH
LDHGTSLEQVMACIRHGFTSVMIDGSKYPFAENVAITKKVVELAHAVGVSVEAELGKIGGTEDDISVDERDAFFTDPEEA
REFVAQTGVDSLAVAIGTAHGRYKGVPKLDFERLAKIRELVHIPLVLHGSSGVPDEDIKKAISLGVAKVNIDTNIREAFV
GKMREVLEKNPDEIDPRKILGPAREAAIEIIREKIRVFGSSNKA

Sequences:

>Translated_284_residues
MALVTVAELLTKAYREGYAVGAFNCNNMEIVQAIVAAAEAENSPVIIQASQGAIKYAGIDYIAALSHQAAKNAKVPVALH
LDHGTSLEQVMACIRHGFTSVMIDGSKYPFAENVAITKKVVELAHAVGVSVEAELGKIGGTEDDISVDERDAFFTDPEEA
REFVAQTGVDSLAVAIGTAHGRYKGVPKLDFERLAKIRELVHIPLVLHGSSGVPDEDIKKAISLGVAKVNIDTNIREAFV
GKMREVLEKNPDEIDPRKILGPAREAAIEIIREKIRVFGSSNKA
>Mature_283_residues
ALVTVAELLTKAYREGYAVGAFNCNNMEIVQAIVAAAEAENSPVIIQASQGAIKYAGIDYIAALSHQAAKNAKVPVALHL
DHGTSLEQVMACIRHGFTSVMIDGSKYPFAENVAITKKVVELAHAVGVSVEAELGKIGGTEDDISVDERDAFFTDPEEAR
EFVAQTGVDSLAVAIGTAHGRYKGVPKLDFERLAKIRELVHIPLVLHGSSGVPDEDIKKAISLGVAKVNIDTNIREAFVG
KMREVLEKNPDEIDPRKILGPAREAAIEIIREKIRVFGSSNKA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=283, Percent_Identity=48.7632508833922, Blast_Score=280, Evalue=8e-77,
Organism=Escherichia coli, GI87082041, Length=284, Percent_Identity=44.7183098591549, Blast_Score=263, Evalue=7e-72,
Organism=Escherichia coli, GI1788072, Length=274, Percent_Identity=40.5109489051095, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI1789293, Length=278, Percent_Identity=29.136690647482, Blast_Score=98, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6322790, Length=293, Percent_Identity=28.6689419795222, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30523; Mature: 30392

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVTVAELLTKAYREGYAVGAFNCNNMEIVQAIVAAAEAENSPVIIQASQGAIKYAGID
CHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEECCHH
YIAALSHQAAKNAKVPVALHLDHGTSLEQVMACIRHGFTSVMIDGSKYPFAENVAITKKV
HHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHH
VELAHAVGVSVEAELGKIGGTEDDISVDERDAFFTDPEEAREFVAQTGVDSLAVAIGTAH
HHHHHHHCCCEEHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCC
GRYKGVPKLDFERLAKIRELVHIPLVLHGSSGVPDEDIKKAISLGVAKVNIDTNIREAFV
CCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCEEEEECCCHHHHHHH
GKMREVLEKNPDEIDPRKILGPAREAAIEIIREKIRVFGSSNKA
HHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALVTVAELLTKAYREGYAVGAFNCNNMEIVQAIVAAAEAENSPVIIQASQGAIKYAGID
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEECCHH
YIAALSHQAAKNAKVPVALHLDHGTSLEQVMACIRHGFTSVMIDGSKYPFAENVAITKKV
HHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHH
VELAHAVGVSVEAELGKIGGTEDDISVDERDAFFTDPEEAREFVAQTGVDSLAVAIGTAH
HHHHHHHCCCEEHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCC
GRYKGVPKLDFERLAKIRELVHIPLVLHGSSGVPDEDIKKAISLGVAKVNIDTNIREAFV
CCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCEEEEECCCHHHHHHH
GKMREVLEKNPDEIDPRKILGPAREAAIEIIREKIRVFGSSNKA
HHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA