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The map label for this gene is obgE

Identifier: 78042851

GI number: 78042851

Start: 316942

End: 318231

Strand: Direct

Name: obgE

Synonym: CHY_0370

Alternate gene names: 78042851

Gene position: 316942-318231 (Clockwise)

Preceding gene: 78043224

Following gene: 78043508

Centisome position: 13.2

GC content: 48.14

Gene sequence:

>1290_bases
ATGTTTTATGATACGGCAAAAATTTATGTTAAAGCTGGAGATGGGGGTAATGGTTGTGTATCTTTCCGGCGGGAAAAGTA
TGTGCCCAATGGCGGTCCCGATGGAGGCGATGGCGGCCGCGGTGGCAGTGTTATTTTAGTTGGGGATGAAGGTTTAAATA
CGCTTTTGGATTTTCGCTATAAAAGGCATTATAAAGCGCCCAGGGGTGAGCATGGCAAAGGGAGTAACCGTCATGGTAAA
GCCGGCGAAAATCTCTATATTCGGGTGCCGGTAGGAACGGTGGTTAAAGATGAAGCAACCGGCGAAATTTTGGCCGATAT
CACCGAGCACGGTCAGGAAGTAGTGGTAGCAAGAGGCGGAAGGGGGGGCAGGGGCAATGCCCATTTTGCCAGCCCCACCC
ACCAGGCACCAAAGTTTGCGGAACTGGGGGAGCCGGGGGAAGAACGCTGGCTTCTTCTGGAACTAAAGCTTTTAGCCGAT
GTGGGTTTGGTAGGCTATCCCAATGCTGGAAAGTCAACGTTAATTTCCCGGGTAAGTGCGGCCCGCCCCAAAATTGCCGA
TTACCCTTTTACCACCCTTACTCCCAACCTGGGAGTGGTTGAAGTGGGCGAAGGACAGAGTTTCGTCATGGCCGATATTC
CCGGGTTAATTGAGGGTGCTCATGCGGGAGTAGGGTTGGGACACCAGTTTTTACGACATGTAGAACGTACCCGGGTTTTA
TTAATGGTTTTAGACATGAGCGGTTTTGAAGGACGCGATCCGGTAGACGACTTTGAAGTGCTTCTAAAAGAGCTTAAGCT
GTACAACGAACAGCTTTTAACCAAACCCCTCGTAATTGCTGCCAATAAAATGGATACGGCCAATGCGCAGGAAAACTTAG
AAAAATTAAAACAGCATATTGCCGGAAAGTACGAAATCTATCCCATTTCGGCCCTTACCGGTGAAGGACTTAAACCGCTT
ATTTATCGCCTCTGGGAAATTATTTCTACTTTGCCGCGGGAGAGTTTGGAGGTAAAACCACAGAAAGTAATAAAAGAGCA
GCCGGAAGAAGGTTTTGTGGTGGAAAAAGTTGATGGAATATTTGTAGTTAAAGGGAAAAAGATTGAACGGTTGGTGGCTA
TGACCAACTTGGATAACGAGGAAGCGGTTGACCGTTTGCAGCGGACCTTTACCCGAATGGGTTTAGAAGAACAGTTAAAA
CGTGCCGGGGTAAAACCGGGAGACTTGGTGCGGATCGGCAAGTTTGAATTTTATTTTGTCGATGAAACCGAGGGGCTGGA
GGAAGAATAA

Upstream 100 bases:

>100_bases
AAAAAAGAGGTAAAAATTATTTTAGATCATTTTCCCAGGATAGAACTAATAGTTAACGACCAGAAAAGCCAGGAACAGTT
GTTATAGGGAGGTAAAAAAT

Downstream 100 bases:

>100_bases
AAAATCTTAATTGCCGTTGAGACAATTTTATCCACTTTTTTAGCCGGTATAAGCGAATGCGGGATATTTTTAAGTTTTTC
TGTGCGGCCATAATTGAAAA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MFYDTAKIYVKAGDGGNGCVSFRREKYVPNGGPDGGDGGRGGSVILVGDEGLNTLLDFRYKRHYKAPRGEHGKGSNRHGK
AGENLYIRVPVGTVVKDEATGEILADITEHGQEVVVARGGRGGRGNAHFASPTHQAPKFAELGEPGEERWLLLELKLLAD
VGLVGYPNAGKSTLISRVSAARPKIADYPFTTLTPNLGVVEVGEGQSFVMADIPGLIEGAHAGVGLGHQFLRHVERTRVL
LMVLDMSGFEGRDPVDDFEVLLKELKLYNEQLLTKPLVIAANKMDTANAQENLEKLKQHIAGKYEIYPISALTGEGLKPL
IYRLWEIISTLPRESLEVKPQKVIKEQPEEGFVVEKVDGIFVVKGKKIERLVAMTNLDNEEAVDRLQRTFTRMGLEEQLK
RAGVKPGDLVRIGKFEFYFVDETEGLEEE

Sequences:

>Translated_429_residues
MFYDTAKIYVKAGDGGNGCVSFRREKYVPNGGPDGGDGGRGGSVILVGDEGLNTLLDFRYKRHYKAPRGEHGKGSNRHGK
AGENLYIRVPVGTVVKDEATGEILADITEHGQEVVVARGGRGGRGNAHFASPTHQAPKFAELGEPGEERWLLLELKLLAD
VGLVGYPNAGKSTLISRVSAARPKIADYPFTTLTPNLGVVEVGEGQSFVMADIPGLIEGAHAGVGLGHQFLRHVERTRVL
LMVLDMSGFEGRDPVDDFEVLLKELKLYNEQLLTKPLVIAANKMDTANAQENLEKLKQHIAGKYEIYPISALTGEGLKPL
IYRLWEIISTLPRESLEVKPQKVIKEQPEEGFVVEKVDGIFVVKGKKIERLVAMTNLDNEEAVDRLQRTFTRMGLEEQLK
RAGVKPGDLVRIGKFEFYFVDETEGLEEE
>Mature_429_residues
MFYDTAKIYVKAGDGGNGCVSFRREKYVPNGGPDGGDGGRGGSVILVGDEGLNTLLDFRYKRHYKAPRGEHGKGSNRHGK
AGENLYIRVPVGTVVKDEATGEILADITEHGQEVVVARGGRGGRGNAHFASPTHQAPKFAELGEPGEERWLLLELKLLAD
VGLVGYPNAGKSTLISRVSAARPKIADYPFTTLTPNLGVVEVGEGQSFVMADIPGLIEGAHAGVGLGHQFLRHVERTRVL
LMVLDMSGFEGRDPVDDFEVLLKELKLYNEQLLTKPLVIAANKMDTANAQENLEKLKQHIAGKYEIYPISALTGEGLKPL
IYRLWEIISTLPRESLEVKPQKVIKEQPEEGFVVEKVDGIFVVKGKKIERLVAMTNLDNEEAVDRLQRTFTRMGLEEQLK
RAGVKPGDLVRIGKFEFYFVDETEGLEEE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=323, Percent_Identity=45.2012383900929, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI111955139, Length=344, Percent_Identity=37.7906976744186, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI111955063, Length=246, Percent_Identity=39.4308943089431, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4557537, Length=166, Percent_Identity=32.5301204819277, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=30.8823529411765, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=35.4330708661417, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789574, Length=347, Percent_Identity=50.4322766570605, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1787454, Length=284, Percent_Identity=27.8169014084507, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790615, Length=188, Percent_Identity=30.8510638297872, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=328, Percent_Identity=39.3292682926829, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17552324, Length=354, Percent_Identity=30.225988700565, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17509631, Length=140, Percent_Identity=32.1428571428571, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=87, Percent_Identity=41.3793103448276, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=88, Percent_Identity=40.9090909090909, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=193, Percent_Identity=41.4507772020725, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321612, Length=92, Percent_Identity=40.2173913043478, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6321649, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319281, Length=109, Percent_Identity=35.7798165137615, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24585318, Length=304, Percent_Identity=41.7763157894737, Blast_Score=198, Evalue=7e-51,
Organism=Drosophila melanogaster, GI20129375, Length=338, Percent_Identity=40.8284023668639, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24640873, Length=140, Percent_Identity=33.5714285714286, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24640877, Length=140, Percent_Identity=33.5714285714286, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24640875, Length=140, Percent_Identity=33.5714285714286, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356473, Length=89, Percent_Identity=40.4494382022472, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17981711, Length=88, Percent_Identity=40.9090909090909, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_CARHZ (Q3AF51)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359233.1
- HSSP:   Q5SJ29
- ProteinModelPortal:   Q3AF51
- SMR:   Q3AF51
- STRING:   Q3AF51
- GeneID:   3727105
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0370
- NMPDR:   fig|246194.3.peg.529
- TIGR:   CHY_0370
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12297
- BioCyc:   CHYD246194:CHY_0370-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 47187; Mature: 47187

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYDTAKIYVKAGDGGNGCVSFRREKYVPNGGPDGGDGGRGGSVILVGDEGLNTLLDFRY
CCCCEEEEEEEECCCCCCEEHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
KRHYKAPRGEHGKGSNRHGKAGENLYIRVPVGTVVKDEATGEILADITEHGQEVVVARGG
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCHHHHHHHHHCCCEEEEEECC
RGGRGNAHFASPTHQAPKFAELGEPGEERWLLLELKLLADVGLVGYPNAGKSTLISRVSA
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
ARPKIADYPFTTLTPNLGVVEVGEGQSFVMADIPGLIEGAHAGVGLGHQFLRHVERTRVL
CCCCCCCCCCCEECCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
LMVLDMSGFEGRDPVDDFEVLLKELKLYNEQLLTKPLVIAANKMDTANAQENLEKLKQHI
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHH
AGKYEIYPISALTGEGLKPLIYRLWEIISTLPRESLEVKPQKVIKEQPEEGFVVEKVDGI
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEEEECCCE
FVVKGKKIERLVAMTNLDNEEAVDRLQRTFTRMGLEEQLKRAGVKPGDLVRIGKFEFYFV
EEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEECCEEEEEE
DETEGLEEE
ECCCCCCCC
>Mature Secondary Structure
MFYDTAKIYVKAGDGGNGCVSFRREKYVPNGGPDGGDGGRGGSVILVGDEGLNTLLDFRY
CCCCEEEEEEEECCCCCCEEHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHH
KRHYKAPRGEHGKGSNRHGKAGENLYIRVPVGTVVKDEATGEILADITEHGQEVVVARGG
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCHHHHHHHHHCCCEEEEEECC
RGGRGNAHFASPTHQAPKFAELGEPGEERWLLLELKLLADVGLVGYPNAGKSTLISRVSA
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
ARPKIADYPFTTLTPNLGVVEVGEGQSFVMADIPGLIEGAHAGVGLGHQFLRHVERTRVL
CCCCCCCCCCCEECCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
LMVLDMSGFEGRDPVDDFEVLLKELKLYNEQLLTKPLVIAANKMDTANAQENLEKLKQHI
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHH
AGKYEIYPISALTGEGLKPLIYRLWEIISTLPRESLEVKPQKVIKEQPEEGFVVEKVDGI
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEEEECCCE
FVVKGKKIERLVAMTNLDNEEAVDRLQRTFTRMGLEEQLKRAGVKPGDLVRIGKFEFYFV
EEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEECCEEEEEE
DETEGLEEE
ECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA