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The map label for this gene is macB [H]

Identifier: 78042731

GI number: 78042731

Start: 76742

End: 77944

Strand: Direct

Name: macB [H]

Synonym: CHY_0090

Alternate gene names: 78042731

Gene position: 76742-77944 (Clockwise)

Preceding gene: 78043038

Following gene: 78043258

Centisome position: 3.2

GC content: 43.06

Gene sequence:

>1203_bases
ATGATTTATGAAAGCCTGAAAATGGCGTTGGAAAGTATTTTAGCCAATAAACTTCGCACTTTTCTTACTATGCTTGGGAT
TATTATTGGTATAAGCTCGGTTATTGCTATTGTTTCCCTGGGGCAGGGCGGGCAAAATGCTATTACCGGAGAGTTCGAAA
AAATCGGGGTAGCAAGTGTTAACATTAAAGTTGATAGTTCTAAAGCCAGTGCCGGTGACTATTTTACTTTGGATGACGTG
GAAAAAATCAAAGAAAAAGTAGAAACGGTTAAATATGCGGCTATTGAGGTTCAGAAACAAGGGGTGGCAATAACTGACCA
GAAAAACAAGCGGGCTGTAATTTTTGGAGGAACGCTGGATTCGTTTTATACTGATAACGTGGAAATCCTTTACGGAAGGT
TTTTTAACGAACGGGAATTTAACGAAGGAATGGCAGTAGCAATAATTGACAGAAATGCCGCCAAGGCTCTTTTTGGCTAT
GAAGATGCGGTAGGCAACACTTTAAAAATTGGTCCCGCTACTAACCCTAAAAAGGTCACAATTATTGGAGTTTCCAAGGG
CTTCACCGGGCCTTTTGGCGGCGGCGACAACATGCCGGTTTTTGTAACGGTGCCGGTAACCTTTTTTCAGGGGCTGTTTT
CCGGCGAGGTAGTCTTTGATAGTATGACTATTATGGCTACTTCCAAGGATGCTGTCGAGGATGCCGGAAATGCGGCTATT
CGCCTTTTAGAGGCCCGGCACAACAATGGGGGTAACGAAATTTATACGGCGCAAAATGTGATGCAGCAGTTAGAACAGAT
AAATAATGTTTTAGGCATCTTTACGGCATTTATCGGAGCGGTAGCGGCTATTTCCCTCTTGGTTGGCGGTATTGGGGTTA
TGAATATCATGCTGGTGTCGGTTACCGAAAGGACGCGAGAAATAGGGATAAGAAAAGCCATAGGTGCGACTACCACCGAT
ATTTTAATCCAGTTTTTAATGGAATCAATCATTATTTCGTTGATTGGTGGCTTAATTGGCATGTTTGTCGGCATTGTGGG
GGCAAATATTGTGGGAAGTATGATAGGAGTAGTACCGGCTTTGTCGCTAACGGCGGTTTTAGGAGCAATTGTTTTTTCTT
CGGCGGTGGGAATCTTCTTTGGGATATATCCGGCAAGAAAAGCAGCTAAGTTAGATCCGATTGAATCCTTAAGGTATGAG
TAA

Upstream 100 bases:

>100_bases
GATATCGCCCAGCATACTAAGAGGATAATACGTTTTCGTGATGGCCAAATAATATCCGACGAACCGGTGGTAAACCGGAT
TGTATTATAGGGGGGCTACT

Downstream 100 bases:

>100_bases
AGGAGGTGCGGCCGGTGTCTTTAAAGTTTCGGCTTATTCTGTCTTACTTGGCAATGTTAGTGATACCTATTTTATTATCG
GCGGTAGCCAGCTTTTTAGT

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MIYESLKMALESILANKLRTFLTMLGIIIGISSVIAIVSLGQGGQNAITGEFEKIGVASVNIKVDSSKASAGDYFTLDDV
EKIKEKVETVKYAAIEVQKQGVAITDQKNKRAVIFGGTLDSFYTDNVEILYGRFFNEREFNEGMAVAIIDRNAAKALFGY
EDAVGNTLKIGPATNPKKVTIIGVSKGFTGPFGGGDNMPVFVTVPVTFFQGLFSGEVVFDSMTIMATSKDAVEDAGNAAI
RLLEARHNNGGNEIYTAQNVMQQLEQINNVLGIFTAFIGAVAAISLLVGGIGVMNIMLVSVTERTREIGIRKAIGATTTD
ILIQFLMESIIISLIGGLIGMFVGIVGANIVGSMIGVVPALSLTAVLGAIVFSSAVGIFFGIYPARKAAKLDPIESLRYE

Sequences:

>Translated_400_residues
MIYESLKMALESILANKLRTFLTMLGIIIGISSVIAIVSLGQGGQNAITGEFEKIGVASVNIKVDSSKASAGDYFTLDDV
EKIKEKVETVKYAAIEVQKQGVAITDQKNKRAVIFGGTLDSFYTDNVEILYGRFFNEREFNEGMAVAIIDRNAAKALFGY
EDAVGNTLKIGPATNPKKVTIIGVSKGFTGPFGGGDNMPVFVTVPVTFFQGLFSGEVVFDSMTIMATSKDAVEDAGNAAI
RLLEARHNNGGNEIYTAQNVMQQLEQINNVLGIFTAFIGAVAAISLLVGGIGVMNIMLVSVTERTREIGIRKAIGATTTD
ILIQFLMESIIISLIGGLIGMFVGIVGANIVGSMIGVVPALSLTAVLGAIVFSSAVGIFFGIYPARKAAKLDPIESLRYE
>Mature_400_residues
MIYESLKMALESILANKLRTFLTMLGIIIGISSVIAIVSLGQGGQNAITGEFEKIGVASVNIKVDSSKASAGDYFTLDDV
EKIKEKVETVKYAAIEVQKQGVAITDQKNKRAVIFGGTLDSFYTDNVEILYGRFFNEREFNEGMAVAIIDRNAAKALFGY
EDAVGNTLKIGPATNPKKVTIIGVSKGFTGPFGGGDNMPVFVTVPVTFFQGLFSGEVVFDSMTIMATSKDAVEDAGNAAI
RLLEARHNNGGNEIYTAQNVMQQLEQINNVLGIFTAFIGAVAAISLLVGGIGVMNIMLVSVTERTREIGIRKAIGATTTD
ILIQFLMESIIISLIGGLIGMFVGIVGANIVGSMIGVVPALSLTAVLGAIVFSSAVGIFFGIYPARKAAKLDPIESLRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=417, Percent_Identity=34.2925659472422, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42524; Mature: 42524

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYESLKMALESILANKLRTFLTMLGIIIGISSVIAIVSLGQGGQNAITGEFEKIGVASV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCEEEE
NIKVDSSKASAGDYFTLDDVEKIKEKVETVKYAAIEVQKQGVAITDQKNKRAVIFGGTLD
EEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCEEEEECCCHH
SFYTDNVEILYGRFFNEREFNEGMAVAIIDRNAAKALFGYEDAVGNTLKIGPATNPKKVT
HHCCCCEEEEEEHHCCCCCCCCCCEEEEEECCHHHHHHCCHHHCCCEEEECCCCCCCEEE
IIGVSKGFTGPFGGGDNMPVFVTVPVTFFQGLFSGEVVFDSMTIMATSKDAVEDAGNAAI
EEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCEEEECEEEEECCCHHHHHCCHHHE
RLLEARHNNGGNEIYTAQNVMQQLEQINNVLGIFTAFIGAVAAISLLVGGIGVMNIMLVS
EHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTERTREIGIRKAIGATTTDILIQFLMESIIISLIGGLIGMFVGIVGANIVGSMIGVVPA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLTAVLGAIVFSSAVGIFFGIYPARKAAKLDPIESLRYE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MIYESLKMALESILANKLRTFLTMLGIIIGISSVIAIVSLGQGGQNAITGEFEKIGVASV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCEEEE
NIKVDSSKASAGDYFTLDDVEKIKEKVETVKYAAIEVQKQGVAITDQKNKRAVIFGGTLD
EEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHEEEECCCEEEECCCCCEEEEECCCHH
SFYTDNVEILYGRFFNEREFNEGMAVAIIDRNAAKALFGYEDAVGNTLKIGPATNPKKVT
HHCCCCEEEEEEHHCCCCCCCCCCEEEEEECCHHHHHHCCHHHCCCEEEECCCCCCCEEE
IIGVSKGFTGPFGGGDNMPVFVTVPVTFFQGLFSGEVVFDSMTIMATSKDAVEDAGNAAI
EEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCEEEECEEEEECCCHHHHHCCHHHE
RLLEARHNNGGNEIYTAQNVMQQLEQINNVLGIFTAFIGAVAAISLLVGGIGVMNIMLVS
EHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTERTREIGIRKAIGATTTDILIQFLMESIIISLIGGLIGMFVGIVGANIVGSMIGVVPA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLTAVLGAIVFSSAVGIFFGIYPARKAAKLDPIESLRYE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA