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The map label for this gene is ade1

Identifier: 78042715

GI number: 78042715

Start: 601563

End: 603374

Strand: Direct

Name: ade1

Synonym: CHY_0689

Alternate gene names: 78042715

Gene position: 601563-603374 (Clockwise)

Preceding gene: 78045187

Following gene: 78043119

Centisome position: 25.05

GC content: 47.19

Gene sequence:

>1812_bases
ATGGATGCCCAAACCTTTAAGACCGCAATTGTCCGGCGTCGCTTAGTTGATGTTTTAATGAATCCGGAATTAAAAGCGAC
GTTGGTCTTAAAAAACGGTCTGGTAATCAATGTTGTAACTCGGGAGATCTATCCGGCAGACGTGGCAGTTTACGATGAAT
ACATTTTAAAAGTGGGAGATGCTTCCGACCTAATTGGCCCGGAAACGGAAGTGGTGGATTTACAGGGAAAATATTACGTA
TCTCCAGGATTTATCGACTCCCACATGCATTTTGAAAGCAGTATGCTAACCATTTCCGAGTTTAGCCGGTTGTCTATTCC
TTCGGGAACCACTACTTTAGTGGCGGACCCCCACGAAATTGGCAACGCGCTGGGACCTGTTGGTATTAAAGCTATGGCCG
AAGAAACAAAGGTAGTTCCCAACAGGGTATATTTGGTAGTGCCGGCTTTAACTCCCGACTGTCCGGGATTAGAAACCGCG
GGCTATGATATTACTTCCAGGGATATGCCGGAAATACTAAATTACCCCAATGTCATCGGCATCGGGGAACTTCAGGGCTT
TTCCAATGCTAAGTATGTTTATAAATACACCCCGGAAATTATTACCGACTTAATTGCCTCAACAACCTATGCCAAGTCCA
TTGGCAAAATAGTGGATGGTAACGCTCCGGAGCTTTTTGGCAGCGAATTAGCTGCTCATTTAATTGCTGCCGGAACCGAG
GCTTCCTGTCACGAGACCACCACCAAAGAAGAATGTGTGGAAAAACTTCGCTACGGTATGTATGTTTTCATGCGGGAAGG
TTCTACCCAGAAAAACATGGCCGAATGTATCCGGGCGGTTACCGAGGAAGGTCTGGATTCCCGGCGGTTAATTGGGGCTA
CCGATGATATGGTGGCCGAGGATTTAGCCAAAAATGGCCACATGAACTGGGTAGTAGCCCGGATCATTAAACAAGGGATT
GATCCGGTGGAAGCAATCCAAATGGTAACCATTAACCCGGCTACCTACTTTGGCTTAAAACACGTTGGGGTTTTAGCTCC
GGGGAAGATGGCCGATATCGTGGTTATTTCCGACTTAATGGACATGAAAGTGGAAAAAGTTTATATCGGCGGAAAATTAG
TGGCCGAAAAGGGCAAAATGGTAGTTAACATCCCGAAATACACCTACCCCGAAGAGGTAAAACATTCGGTTAAGTGTAAA
CCGGTAACAGCTGAAGCCCTGGAAATCAAAGCTACTGGTAGTAATGCGGTAGTGCGCACCATTGGGTTGATTCCCGACCA
GAACCTTACCGAGTCCTTTGAATTTACCGTTCCGGTTAGTGGGGGTGTGGCACAACCGGATTTAACCCAGGACGTACTAC
CGATTGCGGTGGTGGAAAGATACGGACGAAATGGCAGTATTGGACGGGCTTTTGTTAGAGGTTTTGGGTTAAAGGGCGGT
GCGTTTGCGGAAAGTGTCAGCCACGATGCTCACAACATCATTGTGGTTGGAACCAGTTACCAGGATATGGCGTTAGCGGT
TAACCGGGTTATTGAAATGGGCGGTGGCGTGGCGGTGGTGAAAAACGGCAGGGTTTTAGGCGACCTTCGCCTGCCGGTAG
GAGGTTTAATTACCGACGAGTTAGATGGCTATGAATTATCTCGGAAGATTGCCGAACTCCATCGTTTAACTGCCGTGGAG
CTTGGTTGTACCGTTCATGCACCGTTTATGCATCTGTCGTTTTTAGCTTTGACCACCAGTCCCAAGTGGAAAATTACCGA
CCAGGGTTTAATTGATGTTAATAGTTTTGCCATCATTCCGCCGGTTAAGTAA

Upstream 100 bases:

>100_bases
CTCCCTTTGCGGTACGCCGGGGGGAGGTACCTATCGATGCGGCGATTATCGGTATTGTGGATAAGCTTGAATGGCAACGA
AGTTAAAGAGGAGGTTTTTT

Downstream 100 bases:

>100_bases
GGAGGGGCACTTATATGCAAAAGGTTGATTATTTTCGACCCGAAACCATAGAGGAAGCCCTGGAGCTTTTAGCCGCTGGT
CGGGAAGAGTATAAAATTCT

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase 1; Adenine aminase 1

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MDAQTFKTAIVRRRLVDVLMNPELKATLVLKNGLVINVVTREIYPADVAVYDEYILKVGDASDLIGPETEVVDLQGKYYV
SPGFIDSHMHFESSMLTISEFSRLSIPSGTTTLVADPHEIGNALGPVGIKAMAEETKVVPNRVYLVVPALTPDCPGLETA
GYDITSRDMPEILNYPNVIGIGELQGFSNAKYVYKYTPEIITDLIASTTYAKSIGKIVDGNAPELFGSELAAHLIAAGTE
ASCHETTTKEECVEKLRYGMYVFMREGSTQKNMAECIRAVTEEGLDSRRLIGATDDMVAEDLAKNGHMNWVVARIIKQGI
DPVEAIQMVTINPATYFGLKHVGVLAPGKMADIVVISDLMDMKVEKVYIGGKLVAEKGKMVVNIPKYTYPEEVKHSVKCK
PVTAEALEIKATGSNAVVRTIGLIPDQNLTESFEFTVPVSGGVAQPDLTQDVLPIAVVERYGRNGSIGRAFVRGFGLKGG
AFAESVSHDAHNIIVVGTSYQDMALAVNRVIEMGGGVAVVKNGRVLGDLRLPVGGLITDELDGYELSRKIAELHRLTAVE
LGCTVHAPFMHLSFLALTTSPKWKITDQGLIDVNSFAIIPPVK

Sequences:

>Translated_603_residues
MDAQTFKTAIVRRRLVDVLMNPELKATLVLKNGLVINVVTREIYPADVAVYDEYILKVGDASDLIGPETEVVDLQGKYYV
SPGFIDSHMHFESSMLTISEFSRLSIPSGTTTLVADPHEIGNALGPVGIKAMAEETKVVPNRVYLVVPALTPDCPGLETA
GYDITSRDMPEILNYPNVIGIGELQGFSNAKYVYKYTPEIITDLIASTTYAKSIGKIVDGNAPELFGSELAAHLIAAGTE
ASCHETTTKEECVEKLRYGMYVFMREGSTQKNMAECIRAVTEEGLDSRRLIGATDDMVAEDLAKNGHMNWVVARIIKQGI
DPVEAIQMVTINPATYFGLKHVGVLAPGKMADIVVISDLMDMKVEKVYIGGKLVAEKGKMVVNIPKYTYPEEVKHSVKCK
PVTAEALEIKATGSNAVVRTIGLIPDQNLTESFEFTVPVSGGVAQPDLTQDVLPIAVVERYGRNGSIGRAFVRGFGLKGG
AFAESVSHDAHNIIVVGTSYQDMALAVNRVIEMGGGVAVVKNGRVLGDLRLPVGGLITDELDGYELSRKIAELHRLTAVE
LGCTVHAPFMHLSFLALTTSPKWKITDQGLIDVNSFAIIPPVK
>Mature_603_residues
MDAQTFKTAIVRRRLVDVLMNPELKATLVLKNGLVINVVTREIYPADVAVYDEYILKVGDASDLIGPETEVVDLQGKYYV
SPGFIDSHMHFESSMLTISEFSRLSIPSGTTTLVADPHEIGNALGPVGIKAMAEETKVVPNRVYLVVPALTPDCPGLETA
GYDITSRDMPEILNYPNVIGIGELQGFSNAKYVYKYTPEIITDLIASTTYAKSIGKIVDGNAPELFGSELAAHLIAAGTE
ASCHETTTKEECVEKLRYGMYVFMREGSTQKNMAECIRAVTEEGLDSRRLIGATDDMVAEDLAKNGHMNWVVARIIKQGI
DPVEAIQMVTINPATYFGLKHVGVLAPGKMADIVVISDLMDMKVEKVYIGGKLVAEKGKMVVNIPKYTYPEEVKHSVKCK
PVTAEALEIKATGSNAVVRTIGLIPDQNLTESFEFTVPVSGGVAQPDLTQDVLPIAVVERYGRNGSIGRAFVRGFGLKGG
AFAESVSHDAHNIIVVGTSYQDMALAVNRVIEMGGGVAVVKNGRVLGDLRLPVGGLITDELDGYELSRKIAELHRLTAVE
LGCTVHAPFMHLSFLALTTSPKWKITDQGLIDVNSFAIIPPVK

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=582, Percent_Identity=32.8178694158076, Blast_Score=281, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC1_CARHZ (Q3AE90)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359544.1
- ProteinModelPortal:   Q3AE90
- SMR:   Q3AE90
- STRING:   Q3AE90
- GeneID:   3726965
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0689
- NMPDR:   fig|246194.3.peg.549
- TIGR:   CHY_0689
- eggNOG:   COG1001
- HOGENOM:   HBG725357
- OMA:   TTKEECV
- ProtClustDB:   CLSK941129
- BioCyc:   CHYD246194:CHY_0689-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 65312; Mature: 65312

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAQTFKTAIVRRRLVDVLMNPELKATLVLKNGLVINVVTREIYPADVAVYDEYILKVGD
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEEEEECCCCHHHHHHHHHHEECC
ASDLIGPETEVVDLQGKYYVSPGFIDSHMHFESSMLTISEFSRLSIPSGTTTLVADPHEI
CCCCCCCCCEEEEECCCEEECCCCCCCCCCCCCCEEEHHHHHHCCCCCCCEEEEECHHHH
GNALGPVGIKAMAEETKVVPNRVYLVVPALTPDCPGLETAGYDITSRDMPEILNYPNVIG
HHHCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEE
IGELQGFSNAKYVYKYTPEIITDLIASTTYAKSIGKIVDGNAPELFGSELAAHLIAAGTE
ECCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
ASCHETTTKEECVEKLRYGMYVFMREGSTQKNMAECIRAVTEEGLDSRRLIGATDDMVAE
CCCCCCCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHH
DLAKNGHMNWVVARIIKQGIDPVEAIQMVTINPATYFGLKHVGVLAPGKMADIVVISDLM
HHHHCCCCHHHHHHHHHHCCCHHHEEEEEEECCHHHHCHHHCCEECCCCCEEEEEEHHHH
DMKVEKVYIGGKLVAEKGKMVVNIPKYTYPEEVKHSVKCKPVTAEALEIKATGSNAVVRT
HCEEEEEEECCEEEECCCCEEEECCCCCCHHHHHHCCCCCCEECCEEEEEECCCCEEEEE
IGLIPDQNLTESFEFTVPVSGGVAQPDLTQDVLPIAVVERYGRNGSIGRAFVRGFGLKGG
EECCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
AFAESVSHDAHNIIVVGTSYQDMALAVNRVIEMGGGVAVVKNGRVLGDLRLPVGGLITDE
HHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCEEECC
LDGYELSRKIAELHRLTAVELGCTVHAPFMHLSFLALTTSPKWKITDQGLIDVNSFAIIP
CCCHHHHHHHHHHHHHHHEEECCEEECHHHHEEEEEEECCCCEEECCCCEEEECCEEECC
PVK
CCC
>Mature Secondary Structure
MDAQTFKTAIVRRRLVDVLMNPELKATLVLKNGLVINVVTREIYPADVAVYDEYILKVGD
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEEEEECCCCHHHHHHHHHHEECC
ASDLIGPETEVVDLQGKYYVSPGFIDSHMHFESSMLTISEFSRLSIPSGTTTLVADPHEI
CCCCCCCCCEEEEECCCEEECCCCCCCCCCCCCCEEEHHHHHHCCCCCCCEEEEECHHHH
GNALGPVGIKAMAEETKVVPNRVYLVVPALTPDCPGLETAGYDITSRDMPEILNYPNVIG
HHHCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEE
IGELQGFSNAKYVYKYTPEIITDLIASTTYAKSIGKIVDGNAPELFGSELAAHLIAAGTE
ECCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
ASCHETTTKEECVEKLRYGMYVFMREGSTQKNMAECIRAVTEEGLDSRRLIGATDDMVAE
CCCCCCCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHH
DLAKNGHMNWVVARIIKQGIDPVEAIQMVTINPATYFGLKHVGVLAPGKMADIVVISDLM
HHHHCCCCHHHHHHHHHHCCCHHHEEEEEEECCHHHHCHHHCCEECCCCCEEEEEEHHHH
DMKVEKVYIGGKLVAEKGKMVVNIPKYTYPEEVKHSVKCKPVTAEALEIKATGSNAVVRT
HCEEEEEEECCEEEECCCCEEEECCCCCCHHHHHHCCCCCCEECCEEEEEECCCCEEEEE
IGLIPDQNLTESFEFTVPVSGGVAQPDLTQDVLPIAVVERYGRNGSIGRAFVRGFGLKGG
EECCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
AFAESVSHDAHNIIVVGTSYQDMALAVNRVIEMGGGVAVVKNGRVLGDLRLPVGGLITDE
HHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCEEECC
LDGYELSRKIAELHRLTAVELGCTVHAPFMHLSFLALTTSPKWKITDQGLIDVNSFAIIP
CCCHHHHHHHHHHHHHHHEEECCEEECHHHHEEEEEEECCCCEEECCCCEEEECCEEECC
PVK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA