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The map label for this gene is lldD [H]

Identifier: 78042702

GI number: 78042702

Start: 235597

End: 236619

Strand: Direct

Name: lldD [H]

Synonym: CHY_0269

Alternate gene names: 78042702

Gene position: 235597-236619 (Clockwise)

Preceding gene: 78043283

Following gene: 78043126

Centisome position: 9.81

GC content: 48.0

Gene sequence:

>1023_bases
ATGGACTTAAAAGAAATTAGGGCAACAGCCAGAGAAAAACTCAAAGGATTTTGCCGGGTTTGCCCGGTGTGTGACGGTCG
GGCATGCGCCGGAGAAGTACCGGGAATGGGAGGAGTAGGTACCGGAAAAGCTTTTCAGGAAAATTTACGGGCTCTTTCCC
GGTATAAGTTAAATTTAAGAACGATTCACGGAGTAAAAGAACCGGATTTAACCTTTGAACTTTTTGGGGTTAAGGTAAGC
ATGCCGGTTTTTGCTGCTCCGATTACCGGAACCACTTACAACATGGGCGGAGCGTTAACCGAAGAAGAGTATACTTTAGC
GGTGGCCGAAGGTAGCCTTTTAGCTGGGACCTTAGCTTTTACCGGAGATGGAGCCGATCCCACCATGTACGGTTCGGGGT
TAAAAGCGATTAAAAAAGTGGAGGGTAAAGGTATTCCCATTATTAAACCAAGAGCGCAAGAGGAGATAATTAAAAGGATT
AGAGAAGCGGAAGAAACGGGAGCTATTGCTGTAGGGGTGGATATTGATGGAGCCGGATTACTAACGATGGCTTTAAAGGG
GCAGCCGGTCAGTCCGAAAACCCTGGAAGAAGTAATGGAAATTGTTAATTCCACCAGGCTTCCGTTTATTTTAAAGGGTA
TCATGACCCCTGATGAGGCCGAATTAGCGGTTAGAGCCGGGGCGAAAGCCATTGTGGTTTCCAACCACGGAGGAAGGGTT
TTGGATGAAACTCCCGGGGCTGCCGATGTCCTGCCGGAAATTGCTGCCAGAGTAAAAGGGAAAATCACCATCCTGGCCGA
TGGAGGAGTAAGATCCGGTGTCGATGTTTTAAAACTTTTGGCGCTGGGAGCGGATGGAGTATTAATAGGGCGGCCGATAA
TTGTGGCAGCTTTTGGCGGTGGTGCCGAAGGAGTTAAAATTTACCTTGAGAAAATTAAAAAGGAACTAAGGGAAGCGATG
CTTTTAACCGGAGTTGCGCGGGTGACCGAAGTCCCGGGAACAATTATCCGGAAGGAGCAGTAA

Upstream 100 bases:

>100_bases
ACGCCGGGCTGACTTGGTGGTACCGGCTAATGATGAGGATGGAATTGCTTATTTAATAAATGAAATTATTTTAAAAAATT
AAAAGAAGGGAGAGGTTTTT

Downstream 100 bases:

>100_bases
GATGGGAAATTATGTTGTGGGGATAGACCTGGGAGGTACGAAAATTTATACTGCCCTGGCTAACTTAAATGGTGAAATAG
TGGCGGAAGAAATTGAGCCG

Product: FMN-dependent family dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MDLKEIRATAREKLKGFCRVCPVCDGRACAGEVPGMGGVGTGKAFQENLRALSRYKLNLRTIHGVKEPDLTFELFGVKVS
MPVFAAPITGTTYNMGGALTEEEYTLAVAEGSLLAGTLAFTGDGADPTMYGSGLKAIKKVEGKGIPIIKPRAQEEIIKRI
REAEETGAIAVGVDIDGAGLLTMALKGQPVSPKTLEEVMEIVNSTRLPFILKGIMTPDEAELAVRAGAKAIVVSNHGGRV
LDETPGAADVLPEIAARVKGKITILADGGVRSGVDVLKLLALGADGVLIGRPIIVAAFGGGAEGVKIYLEKIKKELREAM
LLTGVARVTEVPGTIIRKEQ

Sequences:

>Translated_340_residues
MDLKEIRATAREKLKGFCRVCPVCDGRACAGEVPGMGGVGTGKAFQENLRALSRYKLNLRTIHGVKEPDLTFELFGVKVS
MPVFAAPITGTTYNMGGALTEEEYTLAVAEGSLLAGTLAFTGDGADPTMYGSGLKAIKKVEGKGIPIIKPRAQEEIIKRI
REAEETGAIAVGVDIDGAGLLTMALKGQPVSPKTLEEVMEIVNSTRLPFILKGIMTPDEAELAVRAGAKAIVVSNHGGRV
LDETPGAADVLPEIAARVKGKITILADGGVRSGVDVLKLLALGADGVLIGRPIIVAAFGGGAEGVKIYLEKIKKELREAM
LLTGVARVTEVPGTIIRKEQ
>Mature_340_residues
MDLKEIRATAREKLKGFCRVCPVCDGRACAGEVPGMGGVGTGKAFQENLRALSRYKLNLRTIHGVKEPDLTFELFGVKVS
MPVFAAPITGTTYNMGGALTEEEYTLAVAEGSLLAGTLAFTGDGADPTMYGSGLKAIKKVEGKGIPIIKPRAQEEIIKRI
REAEETGAIAVGVDIDGAGLLTMALKGQPVSPKTLEEVMEIVNSTRLPFILKGIMTPDEAELAVRAGAKAIVVSNHGGRV
LDETPGAADVLPEIAARVKGKITILADGGVRSGVDVLKLLALGADGVLIGRPIIVAAFGGGAEGVKIYLEKIKKELREAM
LLTGVARVTEVPGTIIRKEQ

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=345, Percent_Identity=32.463768115942, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI54234014, Length=329, Percent_Identity=31.0030395136778, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI7705393, Length=329, Percent_Identity=31.0030395136778, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI1790033, Length=142, Percent_Identity=47.1830985915493, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193208036, Length=131, Percent_Identity=42.7480916030534, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323587, Length=143, Percent_Identity=37.0629370629371, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281363140, Length=147, Percent_Identity=32.6530612244898, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI78707190, Length=147, Percent_Identity=32.6530612244898, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI78707188, Length=146, Percent_Identity=32.8767123287671, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 35711; Mature: 35711

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKEIRATAREKLKGFCRVCPVCDGRACAGEVPGMGGVGTGKAFQENLRALSRYKLNLR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEE
TIHGVKEPDLTFELFGVKVSMPVFAAPITGTTYNMGGALTEEEYTLAVAEGSLLAGTLAF
EECCCCCCCCEEEEEEEEEECCEEECCCCCCEECCCCCCCCCCEEEEEECCCEEEEEEEE
TGDGADPTMYGSGLKAIKKVEGKGIPIIKPRAQEEIIKRIREAEETGAIAVGVDIDGAGL
ECCCCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCCE
LTMALKGQPVSPKTLEEVMEIVNSTRLPFILKGIMTPDEAELAVRAGAKAIVVSNHGGRV
EEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHCCCEEEEEECCCCEE
LDETPGAADVLPEIAARVKGKITILADGGVRSGVDVLKLLALGADGVLIGRPIIVAAFGG
ECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCEEEEEECC
GAEGVKIYLEKIKKELREAMLLTGVARVTEVPGTIIRKEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
>Mature Secondary Structure
MDLKEIRATAREKLKGFCRVCPVCDGRACAGEVPGMGGVGTGKAFQENLRALSRYKLNLR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEE
TIHGVKEPDLTFELFGVKVSMPVFAAPITGTTYNMGGALTEEEYTLAVAEGSLLAGTLAF
EECCCCCCCCEEEEEEEEEECCEEECCCCCCEECCCCCCCCCCEEEEEECCCEEEEEEEE
TGDGADPTMYGSGLKAIKKVEGKGIPIIKPRAQEEIIKRIREAEETGAIAVGVDIDGAGL
ECCCCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCCE
LTMALKGQPVSPKTLEEVMEIVNSTRLPFILKGIMTPDEAELAVRAGAKAIVVSNHGGRV
EEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHCCCEEEEEECCCCEE
LDETPGAADVLPEIAARVKGKITILADGGVRSGVDVLKLLALGADGVLIGRPIIVAAFGG
ECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCEEEEEECC
GAEGVKIYLEKIKKELREAMLLTGVARVTEVPGTIIRKEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA