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The map label for this gene is yebQ [H]

Identifier: 78042654

GI number: 78042654

Start: 505851

End: 507269

Strand: Direct

Name: yebQ [H]

Synonym: CHY_0588

Alternate gene names: 78042654

Gene position: 505851-507269 (Clockwise)

Preceding gene: 78044507

Following gene: 78044847

Centisome position: 21.06

GC content: 42.78

Gene sequence:

>1419_bases
ATGGAGTACCGGTGGAGAGTAATGTGGGTAGTGGCTCTTGGGACTTTTATGGCGCCACTGGATGCCAGCGTTGTGAATAT
TGCCCTTCTTTCAATAATTAAAGATTTTAAGGCAAGTTTAGCGACCGGAGAATGGGTAATTTTAATTTACCTTCTTTTCA
TCAGCACTCTTTTGCTGACTTATGGACGCCTGGGGGATTTGTACGGTAAAAAATTGGTTTACGTTACGGGCTTTGTAGTT
TTCACTGTTGGTTCTTTGTTATGCGGTCTTTCCCCGACCCTTGGTTTTTTAATAGGAGCGCGGGTTATCCAATCCCTTGG
CGCAGGGATGATGATGGCCATGGCGCCGGCAATTGTTACCGAAGTTTTTCCATCGCAGGAACGGGGAAAGGCTTTGGGGA
TTAATGGCATGATGGTGGCTGCAGCTCTGGCTTTTGGGCCTTCTGCCGGGGGATTTTTAACTCACTTTTTCGGGTGGCGT
TCCGTGTTTTTTATTAATCTCCCTATTGGATTAATTGGGAGTATTTTGGCCTTTAAAATAATTAAGAACGATTTCACGCG
GGAAAAACATTCCTTTGATTTTCTCGGGGCTTTTTTAAGCTTTCTTGGTCTTGGAAGCCTTTTAATCCTTCTTACCTTTT
TTGAAAAATACGGCTTTACCCATCCCTTAATGATTGGTGCCTTGGTTATTTCAATCCTGGCTTTTCTTTTGTTTTTATAC
ACCGAAAAAAAGGTTTCTGAACCAATGGTGGATTTGGGCTTATTTAAAAATCGTGATTTTTCGTTTAGTAACTTAAGTGC
TTTTTTAAGCTATGTTGCCTTGTATCAAGTGGTGTTTTTAATGCCGATTTATCTGCAACAGTTGCGACATTTTACTCCCG
AAAAAGCAGGAATGGTAATGTCGGTGCATCCGTTACTAACAATGATTGTAGCTCCTTTAAGCGGAAGCCTTTCCGACAAA
ATCGGTTCGAAGGTTTTAGCCCCTTTGGGAATGACGGTTATGGCTTTAGGGTTATTTGCCCTTTCCCGTTTAAATAGCGA
GACAACAGTTGGCATAATTATCTTATCTTTAATGTTAATCGGGCTTGGCAGTGCCATTTTTCAGTCGCCCAACAACAGCA
CTATAATGGGGAGTGTGCCGAAAAATCGCCTGGGAACCGCTTCCGGGTTTCTGGCGACAATGCGCAATGTCGGAATGGTA
ATGGGAGTAGCCGTTGCCGGGGCCGTGTTTACCGGCCGGCGTACTTATTATTTAACTTATTATTTGCAAAATCACTATAC
TAAAGAACTTGCAACCGTAAAAGCCTTTGTTTTAGCTTTTAGGGAAGCATTTTTAGTGGGCGCTTTTATTGCCCTGTTGT
CGGCTGCAGCTTCACTGGTAAGATCCCGGGGGCGAAAAGAAAAGCTTTTACAAAAATAA

Upstream 100 bases:

>100_bases
AGGGAAAGATTTCCCGAAGACACGGTGCTAAGATTTACCCAGTTAGTGGAACGTTTTGAACATTTACTGGATATAAAGAA
AAATTAACCTGGAGGTTTTT

Downstream 100 bases:

>100_bases
TTCTGGAGTGTTTACTATGGCCTTAAAAGAACTGGCGAAAAACTTCTGGCGGAAAAACTTTAATTTAAAACCCTTTGAAA
AAGTAATAATTGTTTTTGAT

Product: EmrB/QacA family protein drug resistance transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MEYRWRVMWVVALGTFMAPLDASVVNIALLSIIKDFKASLATGEWVILIYLLFISTLLLTYGRLGDLYGKKLVYVTGFVV
FTVGSLLCGLSPTLGFLIGARVIQSLGAGMMMAMAPAIVTEVFPSQERGKALGINGMMVAAALAFGPSAGGFLTHFFGWR
SVFFINLPIGLIGSILAFKIIKNDFTREKHSFDFLGAFLSFLGLGSLLILLTFFEKYGFTHPLMIGALVISILAFLLFLY
TEKKVSEPMVDLGLFKNRDFSFSNLSAFLSYVALYQVVFLMPIYLQQLRHFTPEKAGMVMSVHPLLTMIVAPLSGSLSDK
IGSKVLAPLGMTVMALGLFALSRLNSETTVGIIILSLMLIGLGSAIFQSPNNSTIMGSVPKNRLGTASGFLATMRNVGMV
MGVAVAGAVFTGRRTYYLTYYLQNHYTKELATVKAFVLAFREAFLVGAFIALLSAAASLVRSRGRKEKLLQK

Sequences:

>Translated_472_residues
MEYRWRVMWVVALGTFMAPLDASVVNIALLSIIKDFKASLATGEWVILIYLLFISTLLLTYGRLGDLYGKKLVYVTGFVV
FTVGSLLCGLSPTLGFLIGARVIQSLGAGMMMAMAPAIVTEVFPSQERGKALGINGMMVAAALAFGPSAGGFLTHFFGWR
SVFFINLPIGLIGSILAFKIIKNDFTREKHSFDFLGAFLSFLGLGSLLILLTFFEKYGFTHPLMIGALVISILAFLLFLY
TEKKVSEPMVDLGLFKNRDFSFSNLSAFLSYVALYQVVFLMPIYLQQLRHFTPEKAGMVMSVHPLLTMIVAPLSGSLSDK
IGSKVLAPLGMTVMALGLFALSRLNSETTVGIIILSLMLIGLGSAIFQSPNNSTIMGSVPKNRLGTASGFLATMRNVGMV
MGVAVAGAVFTGRRTYYLTYYLQNHYTKELATVKAFVLAFREAFLVGAFIALLSAAASLVRSRGRKEKLLQK
>Mature_472_residues
MEYRWRVMWVVALGTFMAPLDASVVNIALLSIIKDFKASLATGEWVILIYLLFISTLLLTYGRLGDLYGKKLVYVTGFVV
FTVGSLLCGLSPTLGFLIGARVIQSLGAGMMMAMAPAIVTEVFPSQERGKALGINGMMVAAALAFGPSAGGFLTHFFGWR
SVFFINLPIGLIGSILAFKIIKNDFTREKHSFDFLGAFLSFLGLGSLLILLTFFEKYGFTHPLMIGALVISILAFLLFLY
TEKKVSEPMVDLGLFKNRDFSFSNLSAFLSYVALYQVVFLMPIYLQQLRHFTPEKAGMVMSVHPLLTMIVAPLSGSLSDK
IGSKVLAPLGMTVMALGLFALSRLNSETTVGIIILSLMLIGLGSAIFQSPNNSTIMGSVPKNRLGTASGFLATMRNVGMV
MGVAVAGAVFTGRRTYYLTYYLQNHYTKELATVKAFVLAFREAFLVGAFIALLSAAASLVRSRGRKEKLLQK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=406, Percent_Identity=33.0049261083744, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI1789042, Length=410, Percent_Identity=25.609756097561, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790195, Length=427, Percent_Identity=29.2740046838407, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1788710, Length=443, Percent_Identity=26.410835214447, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788392, Length=407, Percent_Identity=28.2555282555283, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87082231, Length=197, Percent_Identity=30.9644670050761, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319770, Length=390, Percent_Identity=26.6666666666667, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323735, Length=471, Percent_Identity=22.5053078556263, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6325455, Length=426, Percent_Identity=24.1784037558685, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324264, Length=161, Percent_Identity=24.8447204968944, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321663, Length=150, Percent_Identity=30, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322958, Length=454, Percent_Identity=25.3303964757709, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51435; Mature: 51435

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRWRVMWVVALGTFMAPLDASVVNIALLSIIKDFKASLATGEWVILIYLLFISTLLLT
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YGRLGDLYGKKLVYVTGFVVFTVGSLLCGLSPTLGFLIGARVIQSLGAGMMMAMAPAIVT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EVFPSQERGKALGINGMMVAAALAFGPSAGGFLTHFFGWRSVFFINLPIGLIGSILAFKI
HHCCCHHCCCEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEECCHHHHHHHHHHHH
IKNDFTREKHSFDFLGAFLSFLGLGSLLILLTFFEKYGFTHPLMIGALVISILAFLLFLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TEKKVSEPMVDLGLFKNRDFSFSNLSAFLSYVALYQVVFLMPIYLQQLRHFTPEKAGMVM
HHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
SVHPLLTMIVAPLSGSLSDKIGSKVLAPLGMTVMALGLFALSRLNSETTVGIIILSLMLI
EHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GLGSAIFQSPNNSTIMGSVPKNRLGTASGFLATMRNVGMVMGVAVAGAVFTGRRTYYLTY
HHCHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
YLQNHYTKELATVKAFVLAFREAFLVGAFIALLSAAASLVRSRGRKEKLLQK
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
>Mature Secondary Structure
MEYRWRVMWVVALGTFMAPLDASVVNIALLSIIKDFKASLATGEWVILIYLLFISTLLLT
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YGRLGDLYGKKLVYVTGFVVFTVGSLLCGLSPTLGFLIGARVIQSLGAGMMMAMAPAIVT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EVFPSQERGKALGINGMMVAAALAFGPSAGGFLTHFFGWRSVFFINLPIGLIGSILAFKI
HHCCCHHCCCEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEECCHHHHHHHHHHHH
IKNDFTREKHSFDFLGAFLSFLGLGSLLILLTFFEKYGFTHPLMIGALVISILAFLLFLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TEKKVSEPMVDLGLFKNRDFSFSNLSAFLSYVALYQVVFLMPIYLQQLRHFTPEKAGMVM
HHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
SVHPLLTMIVAPLSGSLSDKIGSKVLAPLGMTVMALGLFALSRLNSETTVGIIILSLMLI
EHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GLGSAIFQSPNNSTIMGSVPKNRLGTASGFLATMRNVGMVMGVAVAGAVFTGRRTYYLTY
HHCHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
YLQNHYTKELATVKAFVLAFREAFLVGAFIALLSAAASLVRSRGRKEKLLQK
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]