Click here to switch to the map view.

The map label for this gene is cirA [H]

Identifier: 77761134

GI number: 77761134

Start: 1346941

End: 1349328

Strand: Reverse

Name: cirA [H]

Synonym: XC_1113

Alternate gene names: 77761134

Gene position: 1349328-1346941 (Counterclockwise)

Preceding gene: 66767442

Following gene: 77761133

Centisome position: 26.21

GC content: 64.15

Gene sequence:

>2388_bases
ATGAATTGCAAGACCAGTCCACTCGCTGTTGCCGTTGTTCTTGCACTCTCGTTTTCCGCTTCAACTGCTGTCGCACAGTC
GCAGGCGCCTACCCAGAAGACCCTCGATACGCTGATCGTGACCGGTACGCGCGTGGCCGATCGCACCGTGGCCGAATCGG
CCTCGCCGATCGACATCATTTCGCCGCAGGCACTGGAATCCACCGGCACCACCGAGCTGGCCACCGCGCTGTCGCGCGCG
ATCCCCTCGCTGAATTTCCCCCGCCCGGCCATCTCCGATGGCTCGGATGCGGTGCGCCCTGCGCAGTTGCGCGGCCTGTC
GCCCGATCAGGTGCTGGTGCTGGTCAACGGCAAGCGCTATCACAGCACCGCGCTGATCAACCTCAACGACACCCAGGGCC
GCGGCTCCTCGCCCGCCGACCTCAACACCATTCCGATCGCCGCCGTGGAGCGCATCGAAGTACTGCGCGATGGCGCATCG
GCGCAATACGGCTCGGACGCGATTGCCGGCGTGATCAACATCGTGCTCAAGGGCAGCGGCGAAGGCGGCAGCGTCAATGG
CCGCTACGGCAAGTACAGCGCCGGCGACGGCGAGCAGTATCAGTTGTCCGGCGATGCAGGCTTCAGCTTTGCCGGTACCG
GCAAGGTGCACCTGGCCGCGCAGGCCGGGCATTCGGATCAGACCAACCGCGCGCTGCCGTTCCAGGGCCGCGTGGAGCAG
CGCTACGGCGATCCCGAAATCGATCAGGGCGCGGTGTCGTTCAACGGCGAATACAGCCCCACCGATTACCTGACCTTCTA
TTCGTTCGGCATGGTCAGCCGGCGCGAAGTGCTCTCCAACGGCTACTTCCGCTTTGCCGGCGACAACCGCAACCGTCCGG
AAATCTACCCGGACGGTTTCCTGCCGCAGATCTACAACGTCAGCAAGGACGTCTCCTGGGTGGGCGGTTTGAAGACCTCC
ACCGAAGGCGGCCTGAACATCGATCTGAGCTACAACTACGGCCAGAACAACCTCACCTTCGATGTGCGCAACAGCTTGAA
CAACAGCTTAGGGCTGGCCAGCCCCACCGACTTCCATGCCGGTACGCTGGAGGTCACCCAGAACGTGCTCAATGCCGACT
TCACCAAGACGCTCGACTGGGGTTTGGCCTACCCGGTTGCCTTGGCATTCGGCGCGGAATGGCGCGGCGAAAAGTTCAAC
CAATCGCCCGGTGATGCGGCGTCCTCGGCCAATGGCGGCATTCCCTCGGCCAACGGCGCGCTGATTCCTGGTGCGCAGGT
GTTCCCGGGCTTCAAGCTCTCCGATGCCGGCTACTACAACCGCAACAGCCACTCGGCCTATGTGGACCTGGAAGCGGATC
TCACCGAAAAGCTGTCGGCCGGCTTGGCCGGGCGCTACGAGAAGTACAGCGACTTCGGCGACACCGCCACCGGCAAGCTG
TCGCTGCGCTACGCGTTAACCGACAAGGTGGCGCTGCGTGCCACCGCCTCCACCGGTTTCCGCGCACCGTCGCTGCAGCA
GCAGAACTTCCAGTCGATTGCCACGCAGTTCCTCAACGTGGCGCAGCCCAATGGCGGCGTGTCGGCGATTCCGTTCGAGA
TCGGCACCTTCCGTACCGACAACCCGGCCGCCATCGCGCTCGGTGCCGAACCGCTCAAGGCCGAAGAGTCCAAGAACTAC
GGCCTGGGCGTGGTGTTGCAGCCGGTGGAGAATCTCTATATCACCGTCGATGCGTACCGCATCGATATCGATGACCGCAT
CGTGCTGTCGGAGAACCTCACCTCCATCGCGGCGCGTAACTACCTGCAGGCCAATGGCTTCCCGGGGATCGGCGGCGGGC
GCTACTTCACCAATGCGGTGGACACCAAGACCCAGGGCGTGGACGGGGTCGGCACCTATCGCTGGAACCTGGACAGCGGC
AGCGTGGAGCTGACCACCGGCTACAACTACAACAAGACCGAGGTCGAACAGATCGCGGCCAATCCGCCCGCGCTGGAAGC
CATCGATCCGGGCGCGGTGCGTATCGGCCGTGCAGAGCTCGGCCGCATCACCGAAGGCACGCCGCGCGACAAGTTCTTCC
TGGGCGGCACCTGGTCGCCGGGCAACTGGTCGTTCACCGGCACCGCTACGCGCTGGGGCGAATTCACCACCTTCGGCACC
AACGCCGGCAGCGACCAGACCTATGCCGCGAAATGGACGCTGGACCTGGCCGCCTCCTACAAGCTGGGCAGCTGGAACTT
CACCGTCGGTGGCGACAACGTGCTCAACGAATATCCGGACCGTCAGGAAGCCGGCCTGGGCACGCGGACCTACCTGCCCT
ACAGCAGCGCCTCGCCGTTCGGTTTCAACGGCGCCTTGGTGTACGCCAACGTGAACTACAAGTGGTAA

Upstream 100 bases:

>100_bases
GTGGTTAATGGTTGGGAACGCACCGCAGCTGCCGCAACGGACGCGGCCCGGGAAGGGGGCCCCTGCGATGCATCCGTTCC
CCACTCGGAGTTGTCACCGC

Downstream 100 bases:

>100_bases
GTCACTAGGACAGCCGGCAACGCCTCCTCGCGGTGGCGTTGCCGGTGCTCCATCGCGGCATCCACCCCGGCGCCTCGGGC
AACGACGCGCCGGGGTGACT

Product: ferric enterobactin receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 795; Mature: 795

Protein sequence:

>795_residues
MNCKTSPLAVAVVLALSFSASTAVAQSQAPTQKTLDTLIVTGTRVADRTVAESASPIDIISPQALESTGTTELATALSRA
IPSLNFPRPAISDGSDAVRPAQLRGLSPDQVLVLVNGKRYHSTALINLNDTQGRGSSPADLNTIPIAAVERIEVLRDGAS
AQYGSDAIAGVINIVLKGSGEGGSVNGRYGKYSAGDGEQYQLSGDAGFSFAGTGKVHLAAQAGHSDQTNRALPFQGRVEQ
RYGDPEIDQGAVSFNGEYSPTDYLTFYSFGMVSRREVLSNGYFRFAGDNRNRPEIYPDGFLPQIYNVSKDVSWVGGLKTS
TEGGLNIDLSYNYGQNNLTFDVRNSLNNSLGLASPTDFHAGTLEVTQNVLNADFTKTLDWGLAYPVALAFGAEWRGEKFN
QSPGDAASSANGGIPSANGALIPGAQVFPGFKLSDAGYYNRNSHSAYVDLEADLTEKLSAGLAGRYEKYSDFGDTATGKL
SLRYALTDKVALRATASTGFRAPSLQQQNFQSIATQFLNVAQPNGGVSAIPFEIGTFRTDNPAAIALGAEPLKAEESKNY
GLGVVLQPVENLYITVDAYRIDIDDRIVLSENLTSIAARNYLQANGFPGIGGGRYFTNAVDTKTQGVDGVGTYRWNLDSG
SVELTTGYNYNKTEVEQIAANPPALEAIDPGAVRIGRAELGRITEGTPRDKFFLGGTWSPGNWSFTGTATRWGEFTTFGT
NAGSDQTYAAKWTLDLAASYKLGSWNFTVGGDNVLNEYPDRQEAGLGTRTYLPYSSASPFGFNGALVYANVNYKW

Sequences:

>Translated_795_residues
MNCKTSPLAVAVVLALSFSASTAVAQSQAPTQKTLDTLIVTGTRVADRTVAESASPIDIISPQALESTGTTELATALSRA
IPSLNFPRPAISDGSDAVRPAQLRGLSPDQVLVLVNGKRYHSTALINLNDTQGRGSSPADLNTIPIAAVERIEVLRDGAS
AQYGSDAIAGVINIVLKGSGEGGSVNGRYGKYSAGDGEQYQLSGDAGFSFAGTGKVHLAAQAGHSDQTNRALPFQGRVEQ
RYGDPEIDQGAVSFNGEYSPTDYLTFYSFGMVSRREVLSNGYFRFAGDNRNRPEIYPDGFLPQIYNVSKDVSWVGGLKTS
TEGGLNIDLSYNYGQNNLTFDVRNSLNNSLGLASPTDFHAGTLEVTQNVLNADFTKTLDWGLAYPVALAFGAEWRGEKFN
QSPGDAASSANGGIPSANGALIPGAQVFPGFKLSDAGYYNRNSHSAYVDLEADLTEKLSAGLAGRYEKYSDFGDTATGKL
SLRYALTDKVALRATASTGFRAPSLQQQNFQSIATQFLNVAQPNGGVSAIPFEIGTFRTDNPAAIALGAEPLKAEESKNY
GLGVVLQPVENLYITVDAYRIDIDDRIVLSENLTSIAARNYLQANGFPGIGGGRYFTNAVDTKTQGVDGVGTYRWNLDSG
SVELTTGYNYNKTEVEQIAANPPALEAIDPGAVRIGRAELGRITEGTPRDKFFLGGTWSPGNWSFTGTATRWGEFTTFGT
NAGSDQTYAAKWTLDLAASYKLGSWNFTVGGDNVLNEYPDRQEAGLGTRTYLPYSSASPFGFNGALVYANVNYKW
>Mature_795_residues
MNCKTSPLAVAVVLALSFSASTAVAQSQAPTQKTLDTLIVTGTRVADRTVAESASPIDIISPQALESTGTTELATALSRA
IPSLNFPRPAISDGSDAVRPAQLRGLSPDQVLVLVNGKRYHSTALINLNDTQGRGSSPADLNTIPIAAVERIEVLRDGAS
AQYGSDAIAGVINIVLKGSGEGGSVNGRYGKYSAGDGEQYQLSGDAGFSFAGTGKVHLAAQAGHSDQTNRALPFQGRVEQ
RYGDPEIDQGAVSFNGEYSPTDYLTFYSFGMVSRREVLSNGYFRFAGDNRNRPEIYPDGFLPQIYNVSKDVSWVGGLKTS
TEGGLNIDLSYNYGQNNLTFDVRNSLNNSLGLASPTDFHAGTLEVTQNVLNADFTKTLDWGLAYPVALAFGAEWRGEKFN
QSPGDAASSANGGIPSANGALIPGAQVFPGFKLSDAGYYNRNSHSAYVDLEADLTEKLSAGLAGRYEKYSDFGDTATGKL
SLRYALTDKVALRATASTGFRAPSLQQQNFQSIATQFLNVAQPNGGVSAIPFEIGTFRTDNPAAIALGAEPLKAEESKNY
GLGVVLQPVENLYITVDAYRIDIDDRIVLSENLTSIAARNYLQANGFPGIGGGRYFTNAVDTKTQGVDGVGTYRWNLDSG
SVELTTGYNYNKTEVEQIAANPPALEAIDPGAVRIGRAELGRITEGTPRDKFFLGGTWSPGNWSFTGTATRWGEFTTFGT
NAGSDQTYAAKWTLDLAASYKLGSWNFTVGGDNVLNEYPDRQEAGLGTRTYLPYSSASPFGFNGALVYANVNYKW

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=610, Percent_Identity=23.7704918032787, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786798, Length=548, Percent_Identity=24.4525547445255, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790405, Length=298, Percent_Identity=27.5167785234899, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 84787; Mature: 84787

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCKTSPLAVAVVLALSFSASTAVAQSQAPTQKTLDTLIVTGTRVADRTVAESASPIDII
CCCCCCHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHEEEEECCCHHHHHHHCCCCCCEEE
SPQALESTGTTELATALSRAIPSLNFPRPAISDGSDAVRPAQLRGLSPDQVLVLVNGKRY
CCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCEE
HSTALINLNDTQGRGSSPADLNTIPIAAVERIEVLRDGASAQYGSDAIAGVINIVLKGSG
EEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHEEEEEEEECCC
EGGSVNGRYGKYSAGDGEQYQLSGDAGFSFAGTGKVHLAAQAGHSDQTNRALPFQGRVEQ
CCCCCCCCCCCCCCCCCCEEEECCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCHHH
RYGDPEIDQGAVSFNGEYSPTDYLTFYSFGMVSRREVLSNGYFRFAGDNRNRPEIYPDGF
HCCCCCCCCCEEEECCCCCCCCEEEEEHHCCHHHHHHHHCCCEEEECCCCCCCCCCCCCC
LPQIYNVSKDVSWVGGLKTSTEGGLNIDLSYNYGQNNLTFDVRNSLNNSLGLASPTDFHA
CHHHHCCCCCCHHHCCCCCCCCCCEEEEEEEECCCCCEEEEEHHCCCCCCCCCCCCCCCC
GTLEVTQNVLNADFTKTLDWGLAYPVALAFGAEWRGEKFNQSPGDAASSANGGIPSANGA
CHHHHHHHHHCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LIPGAQVFPGFKLSDAGYYNRNSHSAYVDLEADLTEKLSAGLAGRYEKYSDFGDTATGKL
CCCCHHHCCCEEECCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCHHHHCCCCCCCCEE
SLRYALTDKVALRATASTGFRAPSLQQQNFQSIATQFLNVAQPNGGVSAIPFEIGTFRTD
EEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECEEECC
NPAAIALGAEPLKAEESKNYGLGVVLQPVENLYITVDAYRIDIDDRIVLSENLTSIAARN
CCCEEEECCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEEECCCCEEEECCCHHHHHHHH
YLQANGFPGIGGGRYFTNAVDTKTQGVDGVGTYRWNLDSGSVELTTGYNYNKTEVEQIAA
HHCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHC
NPPALEAIDPGAVRIGRAELGRITEGTPRDKFFLGGTWSPGNWSFTGTATRWGEFTTFGT
CCCCCCCCCCCCEEECHHHHCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCEEEECC
NAGSDQTYAAKWTLDLAASYKLGSWNFTVGGDNVLNEYPDRQEAGLGTRTYLPYSSASPF
CCCCCCEEEEEEEEEEEEEEEECCEEEEECCCHHHHCCCCHHHCCCCCEEECCCCCCCCC
GFNGALVYANVNYKW
CCCCEEEEEEECCCC
>Mature Secondary Structure
MNCKTSPLAVAVVLALSFSASTAVAQSQAPTQKTLDTLIVTGTRVADRTVAESASPIDII
CCCCCCHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHEEEEECCCHHHHHHHCCCCCCEEE
SPQALESTGTTELATALSRAIPSLNFPRPAISDGSDAVRPAQLRGLSPDQVLVLVNGKRY
CCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCEE
HSTALINLNDTQGRGSSPADLNTIPIAAVERIEVLRDGASAQYGSDAIAGVINIVLKGSG
EEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHEEEEEEEECCC
EGGSVNGRYGKYSAGDGEQYQLSGDAGFSFAGTGKVHLAAQAGHSDQTNRALPFQGRVEQ
CCCCCCCCCCCCCCCCCCEEEECCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCHHH
RYGDPEIDQGAVSFNGEYSPTDYLTFYSFGMVSRREVLSNGYFRFAGDNRNRPEIYPDGF
HCCCCCCCCCEEEECCCCCCCCEEEEEHHCCHHHHHHHHCCCEEEECCCCCCCCCCCCCC
LPQIYNVSKDVSWVGGLKTSTEGGLNIDLSYNYGQNNLTFDVRNSLNNSLGLASPTDFHA
CHHHHCCCCCCHHHCCCCCCCCCCEEEEEEEECCCCCEEEEEHHCCCCCCCCCCCCCCCC
GTLEVTQNVLNADFTKTLDWGLAYPVALAFGAEWRGEKFNQSPGDAASSANGGIPSANGA
CHHHHHHHHHCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LIPGAQVFPGFKLSDAGYYNRNSHSAYVDLEADLTEKLSAGLAGRYEKYSDFGDTATGKL
CCCCHHHCCCEEECCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCHHHHCCCCCCCCEE
SLRYALTDKVALRATASTGFRAPSLQQQNFQSIATQFLNVAQPNGGVSAIPFEIGTFRTD
EEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECEEECC
NPAAIALGAEPLKAEESKNYGLGVVLQPVENLYITVDAYRIDIDDRIVLSENLTSIAARN
CCCEEEECCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEEECCCCEEEECCCHHHHHHHH
YLQANGFPGIGGGRYFTNAVDTKTQGVDGVGTYRWNLDSGSVELTTGYNYNKTEVEQIAA
HHCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHC
NPPALEAIDPGAVRIGRAELGRITEGTPRDKFFLGGTWSPGNWSFTGTATRWGEFTTFGT
CCCCCCCCCCCCEEECHHHHCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCEEEECC
NAGSDQTYAAKWTLDLAASYKLGSWNFTVGGDNVLNEYPDRQEAGLGTRTYLPYSSASPF
CCCCCCEEEEEEEEEEEEEEEECCEEEEECCCHHHHCCCCHHHCCCCCEEECCCCCCCCC
GFNGALVYANVNYKW
CCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]