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The map label for this gene is lytS [H]

Identifier: 77748739

GI number: 77748739

Start: 4396134

End: 4396931

Strand: Reverse

Name: lytS [H]

Synonym: XAC3720

Alternate gene names: 77748739

Gene position: 4396931-4396134 (Counterclockwise)

Preceding gene: 21244446

Following gene: 21244444

Centisome position: 84.96

GC content: 66.29

Gene sequence:

>798_bases
GTGGATCTGTTCGCGGTGGACGAAGGCAGCAATTACGAAAACGCCGAGGCGATCAATCGCGCGGTGGTGCGCCGGGTCGG
CGAGCAGCGTCGCGACGAACAGGCCGCCGCCGAGCAATCGGTCATGGAAAAGGAACTGGCCGTGGCGCGCCTGAATCTGC
TGCATGCGCAGGTCGAGCCGCACTTTCTCTACAACACCCTGGCCAGCGCACAGGTGCTGGCGCGCACCGACCCGCCGCGC
GCCGAGATCATGATCGGCCATCTGATCCAGTACCTGCGCAGCTCGCTGCCCAGCGCCGACGGCGCCATCGCAACCCTGGG
CGAAGAACTCGAACGCACCCAGGCCTACCTGGAGATCCTGCGCATCCGCATGGGCACGCGGCTGGCCTTGCAGGTGGAAG
TTCCCTACGAACTACGTGCGCTGCCGCTGCCGTCGATGATGTTGCAGACATTGGTGGAAAACGCGATCAAGCACGGGCTG
GAAGCCAAGCCCGGTGGTGGCACCGTCTGGATCCTTGCGCGTCGCCACGATGACCATGTCACGCTCACCGTGGCCGACGA
CGGCCAGGGCTTCAACACGCACAGCCACGGCACCGGCATCGGCTTGAAGAACCTGCGCGAGCGCTTGCAGCTGATCTATG
CCGGCAAGGCGAGCTTTGCCATCGTGTCCAACTTCCCCAGCGGTGTGGCGGCTACCCTGAGCCTGCCGCTGCCGACGCAG
TTTGGTGCCGCGCCATCGCCGCCACCGTTGCCCACTGCGGGCGCACAGGCCGCACACGCCGCCCAGGTGCGGGCATGA

Upstream 100 bases:

>100_bases
GCGCTTTGCCATCACCCACAACCAGATCCTGGCGACGATCGCGCCGGGGCAGGGCACCAGCAGCGTCACCGTGTTGTGCG
AGCCTGACGCTGGCGCCTGG

Downstream 100 bases:

>100_bases
GCGCGCTGCGCGCCGTGGTTGCCGAAGACGAGGCCTTGCTGCGGCAGTCGTTGCTGACGCTGCTGGCCGAGGTGTGCCCG
CAGCTGCAGATCGTGGGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: Autolysin sensor kinase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MDLFAVDEGSNYENAEAINRAVVRRVGEQRRDEQAAAEQSVMEKELAVARLNLLHAQVEPHFLYNTLASAQVLARTDPPR
AEIMIGHLIQYLRSSLPSADGAIATLGEELERTQAYLEILRIRMGTRLALQVEVPYELRALPLPSMMLQTLVENAIKHGL
EAKPGGGTVWILARRHDDHVTLTVADDGQGFNTHSHGTGIGLKNLRERLQLIYAGKASFAIVSNFPSGVAATLSLPLPTQ
FGAAPSPPPLPTAGAQAAHAAQVRA

Sequences:

>Translated_265_residues
MDLFAVDEGSNYENAEAINRAVVRRVGEQRRDEQAAAEQSVMEKELAVARLNLLHAQVEPHFLYNTLASAQVLARTDPPR
AEIMIGHLIQYLRSSLPSADGAIATLGEELERTQAYLEILRIRMGTRLALQVEVPYELRALPLPSMMLQTLVENAIKHGL
EAKPGGGTVWILARRHDDHVTLTVADDGQGFNTHSHGTGIGLKNLRERLQLIYAGKASFAIVSNFPSGVAATLSLPLPTQ
FGAAPSPPPLPTAGAQAAHAAQVRA
>Mature_265_residues
MDLFAVDEGSNYENAEAINRAVVRRVGEQRRDEQAAAEQSVMEKELAVARLNLLHAQVEPHFLYNTLASAQVLARTDPPR
AEIMIGHLIQYLRSSLPSADGAIATLGEELERTQAYLEILRIRMGTRLALQVEVPYELRALPLPSMMLQTLVENAIKHGL
EAKPGGGTVWILARRHDDHVTLTVADDGQGFNTHSHGTGIGLKNLRERLQLIYAGKASFAIVSNFPSGVAATLSLPLPTQ
FGAAPSPPPLPTAGAQAAHAAQVRA

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=231, Percent_Identity=32.4675324675325, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788723, Length=175, Percent_Identity=30.8571428571429, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 28670; Mature: 28670

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFAVDEGSNYENAEAINRAVVRRVGEQRRDEQAAAEQSVMEKELAVARLNLLHAQVEP
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HFLYNTLASAQVLARTDPPRAEIMIGHLIQYLRSSLPSADGAIATLGEELERTQAYLEIL
HHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RIRMGTRLALQVEVPYELRALPLPSMMLQTLVENAIKHGLEAKPGGGTVWILARRHDDHV
HHHHCCEEEEEEECCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEE
TLTVADDGQGFNTHSHGTGIGLKNLRERLQLIYAGKASFAIVSNFPSGVAATLSLPLPTQ
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCC
FGAAPSPPPLPTAGAQAAHAAQVRA
CCCCCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MDLFAVDEGSNYENAEAINRAVVRRVGEQRRDEQAAAEQSVMEKELAVARLNLLHAQVEP
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HFLYNTLASAQVLARTDPPRAEIMIGHLIQYLRSSLPSADGAIATLGEELERTQAYLEIL
HHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RIRMGTRLALQVEVPYELRALPLPSMMLQTLVENAIKHGLEAKPGGGTVWILARRHDDHV
HHHHCCEEEEEEECCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEE
TLTVADDGQGFNTHSHGTGIGLKNLRERLQLIYAGKASFAIVSNFPSGVAATLSLPLPTQ
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCC
FGAAPSPPPLPTAGAQAAHAAQVRA
CCCCCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA