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The map label for this gene is pcp [H]

Identifier: 77748661

GI number: 77748661

Start: 2989011

End: 2990582

Strand: Direct

Name: pcp [H]

Synonym: XAC2537

Alternate gene names: 77748661

Gene position: 2989011-2990582 (Clockwise)

Preceding gene: 21243262

Following gene: 21243271

Centisome position: 57.75

GC content: 65.97

Gene sequence:

>1572_bases
ATGCACACGATCCTGGCCGGCAGTGAGCGCCGTACCGCTCCCTCCACCATCGAGGCCGGACAACCGCCGCAGGACGAACG
CCTGCGCGTCCTGCTCGCGGTGCGGATGCCGGCATTGAATGCCGCTGCCGATGCGCTGCTGCAATTGCAGCCCAATACGC
TGCCGGTTGCGTTCACGCGTGCGGAGTTCAGCGAACGCTTCGCCGCCGGTGCGGCAGATCTGCAGGCCGTTGCCGACTTT
GCTGCCAGTTATGGCTTGAGGATCGAGCACGCGCACGCAGACAGCGGCAGCGTGATCCTGGAGGGCACCGTGCAGCAGTG
CGAGGCCGCATTCCAGGTCAGCTTGCGCGACTATATCGATGGTGCGATGCGCTATCGCGGACGCACCGGCCCGGTATCGA
TTCCACAGGCCCTGGGCGGCATCGTCACCGCCGTGCTCGGGCTGGACGCCCGCCCGCAGGCTCAGACCCTGCCCAGCGCG
CCCGAGGCGAGCGCATCCTTGCCGCCTGCGATACAGCCCACTGCACCGGCCGACAGTCGGGATGGTCCGATCATGCAATA
CACGCCGCCGCAGCTGGCGCAGCTCTACGGCTTTCCCGAGCATGACGGGCACGGTCAATGCATCGGCATCATCGTGCTGG
GCGGCGGCTATGCACGCGACCAGATGACCGCCTATTTTGCGCAGCTACGCGTCCCCATGCCGACACTGGTCGATGTGCTG
TTGCCCGGGGCAACCAACGCCGTCAGCCGCGGCAATGCAGATGCCGATGTCGAAGCGCAGATGGATATCCAGATCGCCGG
GGCAATCGCGCCGGGCGCGAAACTGGTGATGTATTTCGCGCCCAACACCGACAACGGTTTTCTGGAAGCGATCAATGCCG
CCATCCACGATGCAGAGCACTCACCTGGCATCATCGCCATCAGCTGGGGTTTCACCGAATCGCAATGGACGCCGCAATCG
CGCCAGGCCTACGACTGTGCGTTTCGGGCCGCTGCGTTGATGGGCATCACCGTGTGCATTGCCGCTGGCGACGATGGCGC
CAGTGACGGGCAGCCAGGATTGAATGTCTGCTTTCCCGCATCCAGTCCGTTCGTGCTCGCCTGCGGCGGCACTCGGCTCC
AGGTAACGGCGGACAGCGCCAACGAACAGGCCTGGGCGAGCGGCGGCGGCGGAGAAAGCAGGTTCTTTGCACGTCCTGCC
TGGCAGAACAATCTGCGCCTCACCGATGCACAGCACCAGTCACGCCAACTGCGCATGCGCGGCGTCCCCGATGTGGCGGC
CAACGCCGATGCGCAGACCGGCTACTACCTGTCGATCAACGGGCAGCCCGCCGTGATGGGCGGCACCAGCGCTGCCGCAC
CGTTATGGGCGGCCTTGCTGGCACGCATCTACGGCGCAAACCGCATGCAACCCCACTTCGTGTTGCCGCGCCTGTACGGC
CACCCGGAGGCATTCCGCGACATCGTTGCCGGCGATAACGCTGGCTTCCGCGCAGCCACCGGCTGGGACGCCAATACCGG
GTTGGGCGTGCCCGACGGTGCGCGCTTGGCTGAGGCATTGCGGCACAACTGA

Upstream 100 bases:

>100_bases
AGCCGTGCGTATCGCGGTGGGTCGCGCAGCACGCGACGGCTGGATTTGGATCTGTACCAACCCACTTTGACTCACCCACT
TCGATGGAGTTCTCCCCAGC

Downstream 100 bases:

>100_bases
GCAGAGCGCCCGGTGCGAGCGTCCGTCGCGACACGTTGGACGACTTGGAAACCGATGTGCAAGCCGGTAGGGCGCTACTC
CATTGCACGCTCGCTTGGCA

Product: peptidase

Products: NA

Alternate protein names: Pepstatin-insensitive carboxyl proteinase; Pseudomonapepsin [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MHTILAGSERRTAPSTIEAGQPPQDERLRVLLAVRMPALNAAADALLQLQPNTLPVAFTRAEFSERFAAGAADLQAVADF
AASYGLRIEHAHADSGSVILEGTVQQCEAAFQVSLRDYIDGAMRYRGRTGPVSIPQALGGIVTAVLGLDARPQAQTLPSA
PEASASLPPAIQPTAPADSRDGPIMQYTPPQLAQLYGFPEHDGHGQCIGIIVLGGGYARDQMTAYFAQLRVPMPTLVDVL
LPGATNAVSRGNADADVEAQMDIQIAGAIAPGAKLVMYFAPNTDNGFLEAINAAIHDAEHSPGIIAISWGFTESQWTPQS
RQAYDCAFRAAALMGITVCIAAGDDGASDGQPGLNVCFPASSPFVLACGGTRLQVTADSANEQAWASGGGGESRFFARPA
WQNNLRLTDAQHQSRQLRMRGVPDVAANADAQTGYYLSINGQPAVMGGTSAAAPLWAALLARIYGANRMQPHFVLPRLYG
HPEAFRDIVAGDNAGFRAATGWDANTGLGVPDGARLAEALRHN

Sequences:

>Translated_523_residues
MHTILAGSERRTAPSTIEAGQPPQDERLRVLLAVRMPALNAAADALLQLQPNTLPVAFTRAEFSERFAAGAADLQAVADF
AASYGLRIEHAHADSGSVILEGTVQQCEAAFQVSLRDYIDGAMRYRGRTGPVSIPQALGGIVTAVLGLDARPQAQTLPSA
PEASASLPPAIQPTAPADSRDGPIMQYTPPQLAQLYGFPEHDGHGQCIGIIVLGGGYARDQMTAYFAQLRVPMPTLVDVL
LPGATNAVSRGNADADVEAQMDIQIAGAIAPGAKLVMYFAPNTDNGFLEAINAAIHDAEHSPGIIAISWGFTESQWTPQS
RQAYDCAFRAAALMGITVCIAAGDDGASDGQPGLNVCFPASSPFVLACGGTRLQVTADSANEQAWASGGGGESRFFARPA
WQNNLRLTDAQHQSRQLRMRGVPDVAANADAQTGYYLSINGQPAVMGGTSAAAPLWAALLARIYGANRMQPHFVLPRLYG
HPEAFRDIVAGDNAGFRAATGWDANTGLGVPDGARLAEALRHN
>Mature_523_residues
MHTILAGSERRTAPSTIEAGQPPQDERLRVLLAVRMPALNAAADALLQLQPNTLPVAFTRAEFSERFAAGAADLQAVADF
AASYGLRIEHAHADSGSVILEGTVQQCEAAFQVSLRDYIDGAMRYRGRTGPVSIPQALGGIVTAVLGLDARPQAQTLPSA
PEASASLPPAIQPTAPADSRDGPIMQYTPPQLAQLYGFPEHDGHGQCIGIIVLGGGYARDQMTAYFAQLRVPMPTLVDVL
LPGATNAVSRGNADADVEAQMDIQIAGAIAPGAKLVMYFAPNTDNGFLEAINAAIHDAEHSPGIIAISWGFTESQWTPQS
RQAYDCAFRAAALMGITVCIAAGDDGASDGQPGLNVCFPASSPFVLACGGTRLQVTADSANEQAWASGGGGESRFFARPA
WQNNLRLTDAQHQSRQLRMRGVPDVAANADAQTGYYLSINGQPAVMGGTSAAAPLWAALLARIYGANRMQPHFVLPRLYG
HPEAFRDIVAGDNAGFRAATGWDANTGLGVPDGARLAEALRHN

Specific function: Unknown

COG id: COG4934

COG function: function code O; Predicted protease

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S53 family [H]

Homologues:

Organism=Homo sapiens, GI5729770, Length=301, Percent_Identity=28.2392026578073, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015366
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF09286 Pro-kuma_activ [H]

EC number: =3.4.21.100 [H]

Molecular weight: Translated: 54969; Mature: 54969

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTILAGSERRTAPSTIEAGQPPQDERLRVLLAVRMPALNAAADALLQLQPNTLPVAFTR
CCCEECCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCHHHHHHHHEEECCCCCEEEEEH
AEFSERFAAGAADLQAVADFAASYGLRIEHAHADSGSVILEGTVQQCEAAFQVSLRDYID
HHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHH
GAMRYRGRTGPVSIPQALGGIVTAVLGLDARPQAQTLPSAPEASASLPPAIQPTAPADSR
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGPIMQYTPPQLAQLYGFPEHDGHGQCIGIIVLGGGYARDQMTAYFAQLRVPMPTLVDVL
CCCEEEECCHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHH
LPGATNAVSRGNADADVEAQMDIQIAGAIAPGAKLVMYFAPNTDNGFLEAINAAIHDAEH
CCCCCCHHHCCCCCCCEEEEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCC
SPGIIAISWGFTESQWTPQSRQAYDCAFRAAALMGITVCIAAGDDGASDGQPGLNVCFPA
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCEEEECC
SSPFVLACGGTRLQVTADSANEQAWASGGGGESRFFARPAWQNNLRLTDAQHQSRQLRMR
CCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCEEECCHHHHHHHHHC
GVPDVAANADAQTGYYLSINGQPAVMGGTSAAAPLWAALLARIYGANRMQPHFVLPRLYG
CCCCHHCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEECCHHCC
HPEAFRDIVAGDNAGFRAATGWDANTGLGVPDGARLAEALRHN
CHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MHTILAGSERRTAPSTIEAGQPPQDERLRVLLAVRMPALNAAADALLQLQPNTLPVAFTR
CCCEECCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCHHHHHHHHEEECCCCCEEEEEH
AEFSERFAAGAADLQAVADFAASYGLRIEHAHADSGSVILEGTVQQCEAAFQVSLRDYID
HHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHH
GAMRYRGRTGPVSIPQALGGIVTAVLGLDARPQAQTLPSAPEASASLPPAIQPTAPADSR
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGPIMQYTPPQLAQLYGFPEHDGHGQCIGIIVLGGGYARDQMTAYFAQLRVPMPTLVDVL
CCCEEEECCHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHH
LPGATNAVSRGNADADVEAQMDIQIAGAIAPGAKLVMYFAPNTDNGFLEAINAAIHDAEH
CCCCCCHHHCCCCCCCEEEEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHCCCC
SPGIIAISWGFTESQWTPQSRQAYDCAFRAAALMGITVCIAAGDDGASDGQPGLNVCFPA
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCEEEECC
SSPFVLACGGTRLQVTADSANEQAWASGGGGESRFFARPAWQNNLRLTDAQHQSRQLRMR
CCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCEEECCHHHHHHHHHC
GVPDVAANADAQTGYYLSINGQPAVMGGTSAAAPLWAALLARIYGANRMQPHFVLPRLYG
CCCCHHCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEECCHHCC
HPEAFRDIVAGDNAGFRAATGWDANTGLGVPDGARLAEALRHN
CHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7929375; 8576087; 10488127; 11747435; 11323721 [H]