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The map label for this gene is hpaF [H]

Identifier: 77748523

GI number: 77748523

Start: 462712

End: 464355

Strand: Reverse

Name: hpaF [H]

Synonym: XAC0393

Alternate gene names: 77748523

Gene position: 464355-462712 (Counterclockwise)

Preceding gene: 21241167

Following gene: 21241165

Centisome position: 8.97

GC content: 63.5

Gene sequence:

>1644_bases
ATGGCAGAGAGGGTTCGAACGGGCTACAACCTGCACGACGGGCAGAGAGATACGTCGCGGGAAGTACTGCAAAGCGTCGC
AGATGCAATCCGCCGTGCAGCGACTCGCCATAGCACCGAGCTTGTCCTCGACTACGGCCTGCCTGCCACGACGCTGCCTG
ACGCGATCGGCCGGCTCGACGCGCTACAGAAATTGACGCTGCTCCATACCGGGCTCCAATCGCTGCCAGACAGCCTGGGG
CAGCTGCACCAGCTCCGCCATTTGCAGATCGCTGGCGCGCTGGGCCTGAAAACGCTGCCACCCTCGTTGACGCGCCTGTC
CAATCTCAGAACCCTTCAATTGACGATGATCCCGTTGGACGAATTGCCCGTAGGCATTGGCCGCATGCAGGGTCTGCGCA
GCCTCACGCTAGGTGGCGGGCACTATGCGCGTCTGCCGGCCAGCATCGTTGAACTGAGCGGATTGACCGAGTTGCGCATG
CCGCACTCTTCGCATTTTCGCGAGTTACCTGAGAACATCGGCCTCATGCAGGGGCTCAGGTCGCTGGAGGTGGCATCGAA
TTCCGAGCTAGAGCAGCTTCCTGGCAGCCTCACCCAGCTGCATCGGCTGGAAAAACTCACCCTGTCGTCCAACCGCCGGC
TGGCGCATTTGCCTGAAGACATCGGCCAACTGCGCGGCTTGACGGAACTCTCGCTCAAAAATTGCGCTGCGCTGCGGCAG
CTGCCCGACAGCGTGGGGGATCTGGCCCAGCTGCAACTGCTGGACCTGCGCGGCACCGGCCTGCAGACCCTTCCACAGTC
GCTGGCACGACTGCCCGCTCAATGCGATATCAAGGTACCGGATCATCTGGCAGGCCAATTGCTGCAAATCCGCGACCCGG
AGCGCGCTGCGCGCGAGCCACAGCGCGCGGCACAGCGACTGGCCGAGAGAAGGCGGCGCGCGCCCGTGCCGGCGGCGCAG
CAGGCCGGGGCATCGTGGAACCGCATGCCCGAGTTCGCGCGCGTGCTGCGCACTGTCGATGCCGACCTGGGCGAGCGTTT
TGACAAGTGGACGCAAGGCTTGGCGCAAACTGCCAGGATCTCCGGCGCATCCATCACGCCGGCCGACATGCCCCTGCTGG
ACCAGGTGGTGACCGAGGCCATTCGCTCACCCGAATTCCGCAGCAGCTTCGGCCAATTTTTGAGCGACCACACCCTCAAG
ACGCTCAACATGGATGGCATGACGCAGGTGGGCGGTTTCGGGCCCGCCGTGCGAGGAGACGTCAAAACCGCGTTTGCCGA
GATGCTCAAGCACAAGCTCATGCACACGCAGGACCACCAGACTGCACTGGGCCTGCTGCAGGACGCCCTGCAAAATCCAG
ACTTGGGGCTTTCCAGGGAGATGCTGCTGCGCAGCAGGAATGAACTCACCGGGCGTGTGGAGATGTGGCCGCCATTGAAG
GCCTATATTTCCATGCACGATGTGGAGGGACAAGCGGCGCAGGATGCGGCGATCACGTGGACGATGGCGCAGTTCGAAGA
AGCGCAGCAGGGTGGCATCGGGGACGCAGAGGCCAAGCAGGAGTCCGAACGTGCGCAGGCCAACGCGAACCGCTTCATCG
AGCAGCGGGCCCGTGTACTGCTCAGGGAATGGGACATCCGTTAG

Upstream 100 bases:

>100_bases
GCGTGCGTCGGGCCAGCCGGCTGCACTCGCGGGAGCCTCTTCTGCGCCACCGCGCAGCATCGAGCACGACATCGACGATT
GGCTTGCGCAAAGCCTACCG

Downstream 100 bases:

>100_bases
GCCCTGGAGACCGGTGATATCGCGCCCGGCACTTTAAACGGCAGGCATGCTGGCGATGTTGATCGCAGAGCTCGGCGGGT
GTTTGCCCGCCGAGCCCATG

Product: HpaF protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MAERVRTGYNLHDGQRDTSREVLQSVADAIRRAATRHSTELVLDYGLPATTLPDAIGRLDALQKLTLLHTGLQSLPDSLG
QLHQLRHLQIAGALGLKTLPPSLTRLSNLRTLQLTMIPLDELPVGIGRMQGLRSLTLGGGHYARLPASIVELSGLTELRM
PHSSHFRELPENIGLMQGLRSLEVASNSELEQLPGSLTQLHRLEKLTLSSNRRLAHLPEDIGQLRGLTELSLKNCAALRQ
LPDSVGDLAQLQLLDLRGTGLQTLPQSLARLPAQCDIKVPDHLAGQLLQIRDPERAAREPQRAAQRLAERRRRAPVPAAQ
QAGASWNRMPEFARVLRTVDADLGERFDKWTQGLAQTARISGASITPADMPLLDQVVTEAIRSPEFRSSFGQFLSDHTLK
TLNMDGMTQVGGFGPAVRGDVKTAFAEMLKHKLMHTQDHQTALGLLQDALQNPDLGLSREMLLRSRNELTGRVEMWPPLK
AYISMHDVEGQAAQDAAITWTMAQFEEAQQGGIGDAEAKQESERAQANANRFIEQRARVLLREWDIR

Sequences:

>Translated_547_residues
MAERVRTGYNLHDGQRDTSREVLQSVADAIRRAATRHSTELVLDYGLPATTLPDAIGRLDALQKLTLLHTGLQSLPDSLG
QLHQLRHLQIAGALGLKTLPPSLTRLSNLRTLQLTMIPLDELPVGIGRMQGLRSLTLGGGHYARLPASIVELSGLTELRM
PHSSHFRELPENIGLMQGLRSLEVASNSELEQLPGSLTQLHRLEKLTLSSNRRLAHLPEDIGQLRGLTELSLKNCAALRQ
LPDSVGDLAQLQLLDLRGTGLQTLPQSLARLPAQCDIKVPDHLAGQLLQIRDPERAAREPQRAAQRLAERRRRAPVPAAQ
QAGASWNRMPEFARVLRTVDADLGERFDKWTQGLAQTARISGASITPADMPLLDQVVTEAIRSPEFRSSFGQFLSDHTLK
TLNMDGMTQVGGFGPAVRGDVKTAFAEMLKHKLMHTQDHQTALGLLQDALQNPDLGLSREMLLRSRNELTGRVEMWPPLK
AYISMHDVEGQAAQDAAITWTMAQFEEAQQGGIGDAEAKQESERAQANANRFIEQRARVLLREWDIR
>Mature_546_residues
AERVRTGYNLHDGQRDTSREVLQSVADAIRRAATRHSTELVLDYGLPATTLPDAIGRLDALQKLTLLHTGLQSLPDSLGQ
LHQLRHLQIAGALGLKTLPPSLTRLSNLRTLQLTMIPLDELPVGIGRMQGLRSLTLGGGHYARLPASIVELSGLTELRMP
HSSHFRELPENIGLMQGLRSLEVASNSELEQLPGSLTQLHRLEKLTLSSNRRLAHLPEDIGQLRGLTELSLKNCAALRQL
PDSVGDLAQLQLLDLRGTGLQTLPQSLARLPAQCDIKVPDHLAGQLLQIRDPERAAREPQRAAQRLAERRRRAPVPAAQQ
AGASWNRMPEFARVLRTVDADLGERFDKWTQGLAQTARISGASITPADMPLLDQVVTEAIRSPEFRSSFGQFLSDHTLKT
LNMDGMTQVGGFGPAVRGDVKTAFAEMLKHKLMHTQDHQTALGLLQDALQNPDLGLSREMLLRSRNELTGRVEMWPPLKA
YISMHDVEGQAAQDAAITWTMAQFEEAQQGGIGDAEAKQESERAQANANRFIEQRARVLLREWDIR

Specific function: Probably involved in host-pathogen interactions. May interact with plant target proteins; may modulate a plant signal transduction pathway [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 22 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI95113664, Length=233, Percent_Identity=35.1931330472103, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI16904383, Length=299, Percent_Identity=28.7625418060201, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI55770895, Length=245, Percent_Identity=31.4285714285714, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI8923909, Length=245, Percent_Identity=31.4285714285714, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI110825984, Length=258, Percent_Identity=34.4961240310078, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI122937315, Length=261, Percent_Identity=28.735632183908, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI21361633, Length=243, Percent_Identity=30.4526748971193, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI41281398, Length=210, Percent_Identity=31.4285714285714, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI187829877, Length=221, Percent_Identity=27.1493212669683, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI62241040, Length=221, Percent_Identity=27.1493212669683, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI187829871, Length=221, Percent_Identity=27.1493212669683, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI45827731, Length=228, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI45827729, Length=228, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI238908508, Length=222, Percent_Identity=26.5765765765766, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI194394161, Length=201, Percent_Identity=31.8407960199005, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI61742784, Length=154, Percent_Identity=38.3116883116883, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI61742786, Length=154, Percent_Identity=38.3116883116883, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI21389431, Length=265, Percent_Identity=24.5283018867925, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI33859670, Length=136, Percent_Identity=34.5588235294118, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI256017174, Length=136, Percent_Identity=34.5588235294118, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI190014581, Length=249, Percent_Identity=27.710843373494, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI256017180, Length=136, Percent_Identity=34.5588235294118, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI197333706, Length=239, Percent_Identity=27.6150627615063, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI34222199, Length=239, Percent_Identity=27.6150627615063, Blast_Score=67, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71991525, Length=226, Percent_Identity=34.5132743362832, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71991531, Length=226, Percent_Identity=34.5132743362832, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71993778, Length=269, Percent_Identity=33.0855018587361, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71993783, Length=245, Percent_Identity=33.0612244897959, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71981160, Length=221, Percent_Identity=31.2217194570136, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71981152, Length=221, Percent_Identity=31.2217194570136, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19922294, Length=277, Percent_Identity=32.4909747292419, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI281362653, Length=278, Percent_Identity=30.9352517985612, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI116007092, Length=277, Percent_Identity=30.3249097472924, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281362657, Length=278, Percent_Identity=30.9352517985612, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI281362651, Length=278, Percent_Identity=30.9352517985612, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24650334, Length=277, Percent_Identity=30.3249097472924, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24650332, Length=277, Percent_Identity=30.3249097472924, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24650336, Length=277, Percent_Identity=30.3249097472924, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24650330, Length=278, Percent_Identity=30.9352517985612, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281362655, Length=278, Percent_Identity=30.9352517985612, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI62472958, Length=277, Percent_Identity=30.3249097472924, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17933612, Length=246, Percent_Identity=30.0813008130081, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221379725, Length=246, Percent_Identity=26.8292682926829, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221379722, Length=246, Percent_Identity=26.8292682926829, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161078260, Length=225, Percent_Identity=30.2222222222222, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161078262, Length=225, Percent_Identity=30.2222222222222, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551891, Length=225, Percent_Identity=30.2222222222222, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161078264, Length=225, Percent_Identity=30.2222222222222, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21358045, Length=233, Percent_Identity=29.6137339055794, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001611 [H]

Pfam domain/function: PF00560 LRR_1 [H]

EC number: NA

Molecular weight: Translated: 60479; Mature: 60348

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERVRTGYNLHDGQRDTSREVLQSVADAIRRAATRHSTELVLDYGLPATTLPDAIGRLD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHH
ALQKLTLLHTGLQSLPDSLGQLHQLRHLQIAGALGLKTLPPSLTRLSNLRTLQLTMIPLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEEEEHH
ELPVGIGRMQGLRSLTLGGGHYARLPASIVELSGLTELRMPHSSHFRELPENIGLMQGLR
HCCCCHHHHHHHHHEECCCCCHHHCCHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHH
SLEVASNSELEQLPGSLTQLHRLEKLTLSSNRRLAHLPEDIGQLRGLTELSLKNCAALRQ
HHHHCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
LPDSVGDLAQLQLLDLRGTGLQTLPQSLARLPAQCDIKVPDHLAGQLLQIRDPERAAREP
CHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHCCH
QRAAQRLAERRRRAPVPAAQQAGASWNRMPEFARVLRTVDADLGERFDKWTQGLAQTARI
HHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGASITPADMPLLDQVVTEAIRSPEFRSSFGQFLSDHTLKTLNMDGMTQVGGFGPAVRGD
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEECCCCCHHCCCCCCCHHHH
VKTAFAEMLKHKLMHTQDHQTALGLLQDALQNPDLGLSREMLLRSRNELTGRVEMWPPLK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEECCCCHH
AYISMHDVEGQAAQDAAITWTMAQFEEAQQGGIGDAEAKQESERAQANANRFIEQRARVL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LREWDIR
HHHHCCC
>Mature Secondary Structure 
AERVRTGYNLHDGQRDTSREVLQSVADAIRRAATRHSTELVLDYGLPATTLPDAIGRLD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHH
ALQKLTLLHTGLQSLPDSLGQLHQLRHLQIAGALGLKTLPPSLTRLSNLRTLQLTMIPLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEEEEHH
ELPVGIGRMQGLRSLTLGGGHYARLPASIVELSGLTELRMPHSSHFRELPENIGLMQGLR
HCCCCHHHHHHHHHEECCCCCHHHCCHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHH
SLEVASNSELEQLPGSLTQLHRLEKLTLSSNRRLAHLPEDIGQLRGLTELSLKNCAALRQ
HHHHCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
LPDSVGDLAQLQLLDLRGTGLQTLPQSLARLPAQCDIKVPDHLAGQLLQIRDPERAAREP
CHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHCCH
QRAAQRLAERRRRAPVPAAQQAGASWNRMPEFARVLRTVDADLGERFDKWTQGLAQTARI
HHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGASITPADMPLLDQVVTEAIRSPEFRSSFGQFLSDHTLKTLNMDGMTQVGGFGPAVRGD
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEECCCCCHHCCCCCCCHHHH
VKTAFAEMLKHKLMHTQDHQTALGLLQDALQNPDLGLSREMLLRSRNELTGRVEMWPPLK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEECCCCHH
AYISMHDVEGQAAQDAAITWTMAQFEEAQQGGIGDAEAKQESERAQANANRFIEQRARVL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LREWDIR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10792715; 11823852 [H]