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The map label for this gene is mcpJ [H]

Identifier: 77465716

GI number: 77465716

Start: 830552

End: 832213

Strand: Reverse

Name: mcpJ [H]

Synonym: RSP_3708

Alternate gene names: 77465716

Gene position: 832213-830552 (Counterclockwise)

Preceding gene: 77465717

Following gene: 77465714

Centisome position: 88.25

GC content: 68.89

Gene sequence:

>1662_bases
ATGACGATCAAGCTCAAGCTCGCCGCGACGTTCCTTGCGGTCTTTCTTCTCTCAGGCATCGCCGGGCTGGTGGCGGTGCG
GGATTTCAATCACATCGACGCACAGCTCACCGAGATGATCGAGAACCAGGTCCAGAACACGGTCAAGGTCCAGGAGCTGA
ACTCCGCGCAGCTTCGGCTGAAGGCGGCGATCCGCGAACATCTCATCACCCGCAACGAGGGGGCCATGCGCCGGCTCGAG
GACGAGATGGTCGAGGCGCGGGCGCAGCAGAAGGACGCCATGGACGCGCTCGAGGCGGCGAAACTGGACCCAGAGGGCCG
CGCCCTGCTCGACGAATACACGGCCCTGCGGAAGGGCATCTCCGAGATCAACAACAAGGCGATCGAATTCTCGAAGAAGA
ACGATCTGGAAGGCGCGTCGAACCTCCTGCTCGACCCGGACTATCTGGCGACCCAGAAGAAGCGCGAGGAGCTGGCCGCC
GCCATCGTCGCCCAGCAGCTCGAGGCGCTTGACGCGGCCGAGAGCGATGTCCAGGCGATCATGGACGAGGCGAAGAAGAT
GCTGATCGGCCTCCTGGCGCTTGCGGGCGTGGTGGGGATTGCGGCTGCCGTCTGGATCACCATGAGCATTGCCGGGGGCC
TGCGCCGGGCGCTCGATCTGTCGAAACGCGTGGCGGCCGGCGACCTGAGCGCCCAGGCGGATGCCCGCGGCCGCGACGAG
ATCGCCGAACTTCTCAAGTCGAACAACCTCATGGTGGAGAAGCTGCGCGAAGTGGTGGGCGGCGTCTCGTCGGTGGCCCG
TCAGGTCTCCTCGGGCAGCGGTGAGATGGCCGCGACCTCCGAACAGCTGAGCCAGGGCGCGAGCGAGCAGGCTTCGGCCA
CCGAAGAAGCCTCGGCCTCGGTCGAGCAGATGGCCGCGAACATCAAGCAGGCCGCCGACAACGCGATGCAGACCGAACGC
ATCGCCTCGAAGGCGGCAGAGGATGCCCGCGCCTCGGGGGCTGCCGTGGAAGAGGCGGTGGGCGCCATGCGGTCGATCGC
CGACAAGATCATGATGGTGCAGGAAATCGCGCGCCAGACCGACCTTCTCGCCCTCAATGCGGCCGTCGAGGCGGCGCGGG
CGGGCGAGCACGGGCGGGGCTTCGCGGTCGTGGCCTCCGAAGTGCGCAAGCTGGCCGAACGCAGCCAGGCCGCCGCGGCC
GAGATCTCGCAGCTCTCGGCGGGCACCGTCCGGGCGGCGACCGGCGCCGGCGAGATGCTGAACCAGCTCGTGCCCGACAT
CGAGAACACCTCGCGGCTCGTGACCGACATCTCGGTGGCCTCGCGGGAACTGGCAGCCGGGGCGCAGCAGGTGGCGACGG
CGATCCAGCAGCTCGACAAGGTGACCCAGCAGAACAGCTCGGCCTCCCAGCAGCTGGCCGGCGGCGCCAACGAACTGTCG
GGCCAGGCGGAGCAGCTCGAGACGACCGTGTCCTTCTTCCGCCTCTCCGAGGCCGCCCCGGCCCCTGCCGCGCCGCAGCT
CCGCATCGTCGAGGGCGGGCGGAAGACCCCCGCCGCCGCGGCGGCTCCGAGCCCCGCGAAGGTGACCCCGGGCGGGTTCA
GCTTCAGCCTCGACGGGTCGGACGACGATCTCGACCGGGCCTTCCAGCGTCAGGGCCGCTGA

Upstream 100 bases:

>100_bases
CTTCCGCCAGATTGTTCCGTCCATACCGGTGGAGCGCTCGACCTGCAGGGCCTTTGAGCGCATCTCGTATGCAGGTTCAT
TACGAGGATAGAGGCCCATC

Downstream 100 bases:

>100_bases
TCCTGCGACCGGCCGTCCCCTGCGGGGCGGCCGGTCAGTCCTTCTCCGTCGGCACCGGCTTGGGGGCCGCCTGACCGTCC
GTCTCGCCGAGCGGCGGCCA

Product: methyl accepting chemotaxis protein

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTIKLKLAATFLAVFLLSGIAGLVAVRDFNHIDAQLTEMIENQVQNTVKVQELNSAQLRLKAAIREHLITRNEGAMRRLE
DEMVEARAQQKDAMDALEAAKLDPEGRALLDEYTALRKGISEINNKAIEFSKKNDLEGASNLLLDPDYLATQKKREELAA
AIVAQQLEALDAAESDVQAIMDEAKKMLIGLLALAGVVGIAAAVWITMSIAGGLRRALDLSKRVAAGDLSAQADARGRDE
IAELLKSNNLMVEKLREVVGGVSSVARQVSSGSGEMAATSEQLSQGASEQASATEEASASVEQMAANIKQAADNAMQTER
IASKAAEDARASGAAVEEAVGAMRSIADKIMMVQEIARQTDLLALNAAVEAARAGEHGRGFAVVASEVRKLAERSQAAAA
EISQLSAGTVRAATGAGEMLNQLVPDIENTSRLVTDISVASRELAAGAQQVATAIQQLDKVTQQNSSASQQLAGGANELS
GQAEQLETTVSFFRLSEAAPAPAAPQLRIVEGGRKTPAAAAAPSPAKVTPGGFSFSLDGSDDDLDRAFQRQGR

Sequences:

>Translated_553_residues
MTIKLKLAATFLAVFLLSGIAGLVAVRDFNHIDAQLTEMIENQVQNTVKVQELNSAQLRLKAAIREHLITRNEGAMRRLE
DEMVEARAQQKDAMDALEAAKLDPEGRALLDEYTALRKGISEINNKAIEFSKKNDLEGASNLLLDPDYLATQKKREELAA
AIVAQQLEALDAAESDVQAIMDEAKKMLIGLLALAGVVGIAAAVWITMSIAGGLRRALDLSKRVAAGDLSAQADARGRDE
IAELLKSNNLMVEKLREVVGGVSSVARQVSSGSGEMAATSEQLSQGASEQASATEEASASVEQMAANIKQAADNAMQTER
IASKAAEDARASGAAVEEAVGAMRSIADKIMMVQEIARQTDLLALNAAVEAARAGEHGRGFAVVASEVRKLAERSQAAAA
EISQLSAGTVRAATGAGEMLNQLVPDIENTSRLVTDISVASRELAAGAQQVATAIQQLDKVTQQNSSASQQLAGGANELS
GQAEQLETTVSFFRLSEAAPAPAAPQLRIVEGGRKTPAAAAAPSPAKVTPGGFSFSLDGSDDDLDRAFQRQGR
>Mature_552_residues
TIKLKLAATFLAVFLLSGIAGLVAVRDFNHIDAQLTEMIENQVQNTVKVQELNSAQLRLKAAIREHLITRNEGAMRRLED
EMVEARAQQKDAMDALEAAKLDPEGRALLDEYTALRKGISEINNKAIEFSKKNDLEGASNLLLDPDYLATQKKREELAAA
IVAQQLEALDAAESDVQAIMDEAKKMLIGLLALAGVVGIAAAVWITMSIAGGLRRALDLSKRVAAGDLSAQADARGRDEI
AELLKSNNLMVEKLREVVGGVSSVARQVSSGSGEMAATSEQLSQGASEQASATEEASASVEQMAANIKQAADNAMQTERI
ASKAAEDARASGAAVEEAVGAMRSIADKIMMVQEIARQTDLLALNAAVEAARAGEHGRGFAVVASEVRKLAERSQAAAAE
ISQLSAGTVRAATGAGEMLNQLVPDIENTSRLVTDISVASRELAAGAQQVATAIQQLDKVTQQNSSASQQLAGGANELSG
QAEQLETTVSFFRLSEAAPAPAAPQLRIVEGGRKTPAAAAAPSPAKVTPGGFSFSLDGSDDDLDRAFQRQGR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=394, Percent_Identity=36.2944162436548, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1788195, Length=335, Percent_Identity=40.8955223880597, Blast_Score=172, Evalue=7e-44,
Organism=Escherichia coli, GI1787690, Length=326, Percent_Identity=37.7300613496933, Blast_Score=172, Evalue=7e-44,
Organism=Escherichia coli, GI1788194, Length=394, Percent_Identity=34.5177664974619, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789453, Length=286, Percent_Identity=31.4685314685315, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 58189; Mature: 58058

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKLKLAATFLAVFLLSGIAGLVAVRDFNHIDAQLTEMIENQVQNTVKVQELNSAQLRL
CEEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
KAAIREHLITRNEGAMRRLEDEMVEARAQQKDAMDALEAAKLDPEGRALLDEYTALRKGI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SEINNKAIEFSKKNDLEGASNLLLDPDYLATQKKREELAAAIVAQQLEALDAAESDVQAI
HHHHHHHEECCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDEAKKMLIGLLALAGVVGIAAAVWITMSIAGGLRRALDLSKRVAAGDLSAQADARGRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
IAELLKSNNLMVEKLREVVGGVSSVARQVSSGSGEMAATSEQLSQGASEQASATEEASAS
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
VEQMAANIKQAADNAMQTERIASKAAEDARASGAAVEEAVGAMRSIADKIMMVQEIARQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLALNAAVEAARAGEHGRGFAVVASEVRKLAERSQAAAAEISQLSAGTVRAATGAGEML
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHH
NQLVPDIENTSRLVTDISVASRELAAGAQQVATAIQQLDKVTQQNSSASQQLAGGANELS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHC
GQAEQLETTVSFFRLSEAAPAPAAPQLRIVEGGRKTPAAAAAPSPAKVTPGGFSFSLDGS
CHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCC
DDDLDRAFQRQGR
CCHHHHHHHHCCC
>Mature Secondary Structure 
TIKLKLAATFLAVFLLSGIAGLVAVRDFNHIDAQLTEMIENQVQNTVKVQELNSAQLRL
EEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
KAAIREHLITRNEGAMRRLEDEMVEARAQQKDAMDALEAAKLDPEGRALLDEYTALRKGI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SEINNKAIEFSKKNDLEGASNLLLDPDYLATQKKREELAAAIVAQQLEALDAAESDVQAI
HHHHHHHEECCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDEAKKMLIGLLALAGVVGIAAAVWITMSIAGGLRRALDLSKRVAAGDLSAQADARGRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
IAELLKSNNLMVEKLREVVGGVSSVARQVSSGSGEMAATSEQLSQGASEQASATEEASAS
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
VEQMAANIKQAADNAMQTERIASKAAEDARASGAAVEEAVGAMRSIADKIMMVQEIARQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLALNAAVEAARAGEHGRGFAVVASEVRKLAERSQAAAAEISQLSAGTVRAATGAGEML
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHH
NQLVPDIENTSRLVTDISVASRELAAGAQQVATAIQQLDKVTQQNSSASQQLAGGANELS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHC
GQAEQLETTVSFFRLSEAAPAPAAPQLRIVEGGRKTPAAAAAPSPAKVTPGGFSFSLDGS
CHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCC
DDDLDRAFQRQGR
CCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]