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The map label for this gene is rbtR [H]

Identifier: 77465708

GI number: 77465708

Start: 821068

End: 822081

Strand: Reverse

Name: rbtR [H]

Synonym: RSP_3700

Alternate gene names: 77465708

Gene position: 822081-821068 (Counterclockwise)

Preceding gene: 77465714

Following gene: 77465703

Centisome position: 87.18

GC content: 70.02

Gene sequence:

>1014_bases
GTGGTCGAGAAGGGCAAGCCGGAACCGGGATCGCGGAATGCGGCCCGCCGCACAACGATTTACGATCTGGCGGCACTGGC
CGAGACCTCGGCCAGCGCGGTCTCGGCGGTGCTGAACGGGACATGGAAGAAGCGGCGGATCAGCGAGCGGCTGGCCGAGC
GCATCCTGCGAGTCGCCGAAGAGCAGGGCTATTCGGTCAATCTGCAGGCCAGCGTCCTGCGGCGCGAGAAGTCGAACATC
GTGGGCATGATCATGCCGAAATACGACAACCGATATTTCGGCGCCATCGCCGAGCGGTTCGAGGCGCGGGCCCGGGCGCA
GGGGCTGTTTCCGGTCATCACCTGCACCCAGCGCGACCCGGAGCTGGAGTTCGAGGCCGCGCGCGAGATGATCTCCTATC
AGGTGGAATGCCTGATCGCGACGGGCGCCACCGATCCCGACCGGATCAGCGACTTCTGCGCGGCGGCAGGGGTGCAGGCG
ATCAACCTCGACCTGCCGGGCGGGCGGGCGCCTTCGGTCGTGTCGGACAATTTCGGCGGCGCGCGCGATCTCGCGCATCT
GCTTCTCGAGCGCGCCCCGCACGAGGCCCTGCTCTTCATCGGCGGGCGTCCGTCGGATCACAACACGGCCGAGCGGATCC
GGGGCTTCCGCGCAGCCCACGCCGACCGCGGCATCCCGCTGCCCGAGAGCGCGATCCTCGCCTGCGGCTATGCGGCCGAG
AAGGCCGAGGCCGCGCTCGAGGCGCGGGCGGGCGACCTGCCGCGCGGCCTCTTCGTCAATTCCACCATCACGCTCGAAGG
GGTGGTCCGCTGGCTGCGCCGCCAGTCGCCGCCGGCACCGGTCGAGATCGGCACCTTCGACTGGGACCCGTTCGCGGCGC
TGCTGCCCGACTGCGTGGGCATGGTCGAGCAGGATGTGGCGGGGATGCTGGAGGAGGTCTTCCGCCTGATCGGCCATGCG
CCGGACGCGGGGCTGCGGATCGAGGTGCCGACGATCCTGCGCCGCCACCTCTGA

Upstream 100 bases:

>100_bases
CAGGCTGGCGCTATCGATTGCGCAACCATGCTCAATCGATGTAGCATGATTGTTACGAGGCACGGGCGATGTCAAGATGC
TCTCTAGGGGAGGAGCGGGA

Downstream 100 bases:

>100_bases
CCGCCGGGCTGCCCTTGCTCCGGGCCGAGTGACCGATCCACGCGCCCTCCGCGTCAGGGGGCAGGGCAGTTGCCGGCTGT
CCCGAGGCCTCAGCCGCGCC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Rbt operon repressor [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MVEKGKPEPGSRNAARRTTIYDLAALAETSASAVSAVLNGTWKKRRISERLAERILRVAEEQGYSVNLQASVLRREKSNI
VGMIMPKYDNRYFGAIAERFEARARAQGLFPVITCTQRDPELEFEAAREMISYQVECLIATGATDPDRISDFCAAAGVQA
INLDLPGGRAPSVVSDNFGGARDLAHLLLERAPHEALLFIGGRPSDHNTAERIRGFRAAHADRGIPLPESAILACGYAAE
KAEAALEARAGDLPRGLFVNSTITLEGVVRWLRRQSPPAPVEIGTFDWDPFAALLPDCVGMVEQDVAGMLEEVFRLIGHA
PDAGLRIEVPTILRRHL

Sequences:

>Translated_337_residues
MVEKGKPEPGSRNAARRTTIYDLAALAETSASAVSAVLNGTWKKRRISERLAERILRVAEEQGYSVNLQASVLRREKSNI
VGMIMPKYDNRYFGAIAERFEARARAQGLFPVITCTQRDPELEFEAAREMISYQVECLIATGATDPDRISDFCAAAGVQA
INLDLPGGRAPSVVSDNFGGARDLAHLLLERAPHEALLFIGGRPSDHNTAERIRGFRAAHADRGIPLPESAILACGYAAE
KAEAALEARAGDLPRGLFVNSTITLEGVVRWLRRQSPPAPVEIGTFDWDPFAALLPDCVGMVEQDVAGMLEEVFRLIGHA
PDAGLRIEVPTILRRHL
>Mature_337_residues
MVEKGKPEPGSRNAARRTTIYDLAALAETSASAVSAVLNGTWKKRRISERLAERILRVAEEQGYSVNLQASVLRREKSNI
VGMIMPKYDNRYFGAIAERFEARARAQGLFPVITCTQRDPELEFEAAREMISYQVECLIATGATDPDRISDFCAAAGVQA
INLDLPGGRAPSVVSDNFGGARDLAHLLLERAPHEALLFIGGRPSDHNTAERIRGFRAAHADRGIPLPESAILACGYAAE
KAEAALEARAGDLPRGLFVNSTITLEGVVRWLRRQSPPAPVEIGTFDWDPFAALLPDCVGMVEQDVAGMLEEVFRLIGHA
PDAGLRIEVPTILRRHL

Specific function: Repressor for the genes of the ribitol operon. Binds D- ribulose as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786268, Length=306, Percent_Identity=27.7777777777778, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787906, Length=240, Percent_Identity=28.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787580, Length=322, Percent_Identity=24.8447204968944, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788474, Length=329, Percent_Identity=25.2279635258359, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994940, Length=222, Percent_Identity=24.7747747747748, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36790; Mature: 36790

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEKGKPEPGSRNAARRTTIYDLAALAETSASAVSAVLNGTWKKRRISERLAERILRVAE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EQGYSVNLQASVLRREKSNIVGMIMPKYDNRYFGAIAERFEARARAQGLFPVITCTQRDP
HCCCEEEHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
ELEFEAAREMISYQVECLIATGATDPDRISDFCAAAGVQAINLDLPGGRAPSVVSDNFGG
CCHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCC
ARDLAHLLLERAPHEALLFIGGRPSDHNTAERIRGFRAAHADRGIPLPESAILACGYAAE
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHH
KAEAALEARAGDLPRGLFVNSTITLEGVVRWLRRQSPPAPVEIGTFDWDPFAALLPDCVG
HHHHHHHHHCCCCCCCEEECCEEEHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHH
MVEQDVAGMLEEVFRLIGHAPDAGLRIEVPTILRRHL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHCC
>Mature Secondary Structure
MVEKGKPEPGSRNAARRTTIYDLAALAETSASAVSAVLNGTWKKRRISERLAERILRVAE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EQGYSVNLQASVLRREKSNIVGMIMPKYDNRYFGAIAERFEARARAQGLFPVITCTQRDP
HCCCEEEHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
ELEFEAAREMISYQVECLIATGATDPDRISDFCAAAGVQAINLDLPGGRAPSVVSDNFGG
CCHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCC
ARDLAHLLLERAPHEALLFIGGRPSDHNTAERIRGFRAAHADRGIPLPESAILACGYAAE
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHH
KAEAALEARAGDLPRGLFVNSTITLEGVVRWLRRQSPPAPVEIGTFDWDPFAALLPDCVG
HHHHHHHHHCCCCCCCEEECCEEEHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHH
MVEQDVAGMLEEVFRLIGHAPDAGLRIEVPTILRRHL
HHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3891331 [H]